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The map label for this gene is moeB [H]

Identifier: 82702247

GI number: 82702247

Start: 1289103

End: 1289855

Strand: Reverse

Name: moeB [H]

Synonym: Nmul_A1118

Alternate gene names: 82702247

Gene position: 1289855-1289103 (Counterclockwise)

Preceding gene: 82702248

Following gene: 82702239

Centisome position: 40.51

GC content: 54.58

Gene sequence:

>753_bases
ATGAATGACGATCAGTTGCTGCGTTACAGCCGTCACATCCTGTTGCCGGAGATAGGAATACAGGGGCAGGAAGCCTTGAT
CCGGTCGCATGTACTGGTAGTCGGGGCGGGAGGACTCGGCTCTCCTGCCAGCATGTACCTTGCCTCGAGCGGAGTCGGCA
CGCTCACTATCTGTGACAATGACAGGGTTGACCTGACCAACCTCCAGCGCCAGATCATTCACGGTACAGACGACATTGGC
GCACCAAAAACACACTCTGCCAGAAAAACTCTTGCGAAAATCAACCCTGAAGTCGAAGTGATCGAACTCGACGAGCGTAT
GGATGAAAAAAGATTGCTGCAACTGGTCGGAGACGCCGACGTGGTCGTGGACGCAAGCGATAACTTTTCCACCCGTTATG
CTATCAACCATTCTTGTGTCCTTCTCCGCAAGCCGCTCGTATCAGGTGCAGCCGTGCGTTTTGAGGGGCAAATCGCGGTA
TTCGATCTCAGGCACCCAGACAATCCATGCTATCACTGCTTGTTTCCAGCAGGCGGGGAAGATCAGGACATGCGCTGCGG
GGTGATGGGCGTGCTTGCACCGCTGGTAGGAATCATTGGCTGCATGCAGGCTGCAGAAACACTAAAAATTCTCACCAACG
CCGGCCAAACCTTGAACGGCCGCCTGCTTACGCTGGACGGTCTTGCCATGAAATGGAAATCATCCGAACTGAGAAAGGAT
CCAGGGTGCGAGGTTTGCGGAAACCCAGCGTAG

Upstream 100 bases:

>100_bases
TTGGTTGCCACGCATCCGCGATGTTCCCTATGCCCTTCTTCTGAAAAAGGACGATGTCCGTATCACTCTCACTCGCGGAC
TGCAGCGAAACATTTTCCAA

Downstream 100 bases:

>100_bases
CGCTTGCGTTCCGAGGGGGCCGAGGAACCCAGCGCATACCCCTCCCGGCGGTTTCACCAGGCACCCCTTTCGCACCGATT
TAAACAGTGCTGTGGGGCTT

Product: UBA/THIF-type NAD/FAD binding domain-containing protein

Products: NA

Alternate protein names: MoaD protein adenylase; Molybdopterin-converting factor subunit 1 adenylase [H]

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MNDDQLLRYSRHILLPEIGIQGQEALIRSHVLVVGAGGLGSPASMYLASSGVGTLTICDNDRVDLTNLQRQIIHGTDDIG
APKTHSARKTLAKINPEVEVIELDERMDEKRLLQLVGDADVVVDASDNFSTRYAINHSCVLLRKPLVSGAAVRFEGQIAV
FDLRHPDNPCYHCLFPAGGEDQDMRCGVMGVLAPLVGIIGCMQAAETLKILTNAGQTLNGRLLTLDGLAMKWKSSELRKD
PGCEVCGNPA

Sequences:

>Translated_250_residues
MNDDQLLRYSRHILLPEIGIQGQEALIRSHVLVVGAGGLGSPASMYLASSGVGTLTICDNDRVDLTNLQRQIIHGTDDIG
APKTHSARKTLAKINPEVEVIELDERMDEKRLLQLVGDADVVVDASDNFSTRYAINHSCVLLRKPLVSGAAVRFEGQIAV
FDLRHPDNPCYHCLFPAGGEDQDMRCGVMGVLAPLVGIIGCMQAAETLKILTNAGQTLNGRLLTLDGLAMKWKSSELRKD
PGCEVCGNPA
>Mature_250_residues
MNDDQLLRYSRHILLPEIGIQGQEALIRSHVLVVGAGGLGSPASMYLASSGVGTLTICDNDRVDLTNLQRQIIHGTDDIG
APKTHSARKTLAKINPEVEVIELDERMDEKRLLQLVGDADVVVDASDNFSTRYAINHSCVLLRKPLVSGAAVRFEGQIAV
FDLRHPDNPCYHCLFPAGGEDQDMRCGVMGVLAPLVGIIGCMQAAETLKILTNAGQTLNGRLLTLDGLAMKWKSSELRKD
PGCEVCGNPA

Specific function: Catalyzes the adenylation by ATP of the carboxyl group of the C-terminal glycine of sulfur carrier protein moaD [H]

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesA/moeB/thiF family [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=230, Percent_Identity=44.3478260869565, Blast_Score=177, Evalue=8e-45,
Organism=Homo sapiens, GI38045948, Length=164, Percent_Identity=31.7073170731707, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI4885649, Length=151, Percent_Identity=26.4900662251656, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1787048, Length=248, Percent_Identity=43.9516129032258, Blast_Score=222, Evalue=2e-59,
Organism=Escherichia coli, GI87082356, Length=248, Percent_Identity=43.9516129032258, Blast_Score=196, Evalue=1e-51,
Organism=Escherichia coli, GI1789177, Length=139, Percent_Identity=34.5323741007194, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17540406, Length=262, Percent_Identity=42.3664122137405, Blast_Score=203, Evalue=7e-53,
Organism=Caenorhabditis elegans, GI193203301, Length=155, Percent_Identity=26.4516129032258, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI86565433, Length=152, Percent_Identity=28.9473684210526, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI86565431, Length=152, Percent_Identity=28.9473684210526, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6321903, Length=250, Percent_Identity=32.4, Blast_Score=142, Evalue=7e-35,
Organism=Saccharomyces cerevisiae, GI6322639, Length=165, Percent_Identity=26.6666666666667, Blast_Score=68, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320598, Length=140, Percent_Identity=31.4285714285714, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24582879, Length=249, Percent_Identity=40.5622489959839, Blast_Score=198, Evalue=3e-51,
Organism=Drosophila melanogaster, GI24660640, Length=152, Percent_Identity=29.6052631578947, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI28573937, Length=161, Percent_Identity=29.8136645962733, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR012730
- InterPro:   IPR016040
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 26996; Mature: 26996

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDDQLLRYSRHILLPEIGIQGQEALIRSHVLVVGAGGLGSPASMYLASSGVGTLTICDN
CCCHHHHHHHCCEECCCCCCCCHHHHHHCEEEEEECCCCCCCHHEEEECCCCEEEEEECC
DRVDLTNLQRQIIHGTDDIGAPKTHSARKTLAKINPEVEVIELDERMDEKRLLQLVGDAD
CCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCEEEEECCHHCCHHHHHHHHCCCE
VVVDASDNFSTRYAINHSCVLLRKPLVSGAAVRFEGQIAVFDLRHPDNPCYHCLFPAGGE
EEEECCCCCCEEEEECCCEEEEECCCCCCEEEEEECCEEEEEECCCCCCCEEEEECCCCC
DQDMRCGVMGVLAPLVGIIGCMQAAETLKILTNAGQTLNGRLLTLDGLAMKWKSSELRKD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCEEEEECCCHHCCC
PGCEVCGNPA
CCCCCCCCCC
>Mature Secondary Structure
MNDDQLLRYSRHILLPEIGIQGQEALIRSHVLVVGAGGLGSPASMYLASSGVGTLTICDN
CCCHHHHHHHCCEECCCCCCCCHHHHHHCEEEEEECCCCCCCHHEEEECCCCEEEEEECC
DRVDLTNLQRQIIHGTDDIGAPKTHSARKTLAKINPEVEVIELDERMDEKRLLQLVGDAD
CCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCEEEEECCHHCCHHHHHHHHCCCE
VVVDASDNFSTRYAINHSCVLLRKPLVSGAAVRFEGQIAVFDLRHPDNPCYHCLFPAGGE
EEEECCCCCCEEEEECCCEEEEECCCCCCEEEEEECCEEEEEECCCCCCCEEEEECCCCC
DQDMRCGVMGVLAPLVGIIGCMQAAETLKILTNAGQTLNGRLLTLDGLAMKWKSSELRKD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCEEEEECCCHHCCC
PGCEVCGNPA
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3045084; 8905232; 9278503 [H]