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The map label for this gene is nhaR [H]

Identifier: 82702239

GI number: 82702239

Start: 1279720

End: 1280628

Strand: Reverse

Name: nhaR [H]

Synonym: Nmul_A1110

Alternate gene names: 82702239

Gene position: 1280628-1279720 (Counterclockwise)

Preceding gene: 82702247

Following gene: 82702237

Centisome position: 40.22

GC content: 55.89

Gene sequence:

>909_bases
ATGCTTAATTACAAGCAATTGAATTATTTCTGGGCAGTGGCCAAGGCAGGCAGCATTGTCCGCGCAAGCGAACGCCTGAA
TCTCACGCCCCAGACTCTGAGCGGCCAGATCGGATTATTGGAAGACGCGCTGGGGGTGCCACTTTTTTTACGAGTGGGGA
GACGCCTTGAATTGACCGAAACAGGACGACTTGCCCTCTCGTATGCCGACGAAATCTTTCAGATTGGAAATGAACTGGAA
GAAGCATTGCGGGCCCGCCCGGAACGTCATGCGATTCCATTCCGGGTGGGTGTCGACGATGCCGTCCCCAAGTCCATCGC
CTACCGATTGTTAACGCCTGCCATGGGACTTGCTTCGCCTGTACGCATTGTCTGCCGCGAGGACAAACTGGCGCGTTTGC
TGGTGGAATTGGCGATCCAGCGAGTCGATCTGATACTTGCCGACCGCCCCATGCCGGATGAAGCGAATGTGAAAGGCTAC
AGCCATAAGCTGGGAAACTGCGGCATTACATTTTTTGCCGCGCCGTGTCTTGCAAAAACCTTCAAAAAAAAATGGCCTCA
TGTTCTTGATGCGGCCCCCTTGCTCATTCCCGGTAAAGACGCCGCCATACGGCTACCATTGATGCGATGGTTCGACGTGC
ACCAACTCCGCCCCCACATCGTGGGAGAGTTCGACGATAGCGCATTGATGCAGGCATTCGGACAGGCCGGCATCGGCATT
TTCATTGCACCATCCGTAATAGCTGACGAGGTGCAGCGTGAACATGGCGTTGTTGTTGTCGGCTGCACCGACGAGGTTAC
CGAACAGTTTTACGCCATCTCCCTGGAACGCCGTCTCACACACCCCGCCGTCGTCGCCATCAACGACACAGCCCACCGGG
AGCTATTCGCGACCCTGGCTGCCTCCTGA

Upstream 100 bases:

>100_bases
TCATCGGATTTAGTCTAGATGAGAAATTGCATCAAGGAAAGTAGTATCTTGCTGATGATATAATCGGTTTTAACGAAGTA
TTGTATTCGCTTGCATATCG

Downstream 100 bases:

>100_bases
CCCGGATATTTCACCCGGATCATGGGAGAGGGACAAGGTGTTCCGGGTGCAGATTTGCGCATCCCGCGCCGAACCAATAG
CCAGGACTATTGGCGCGAGG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Na(+)/H(+) antiporter regulatory protein [H]

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MLNYKQLNYFWAVAKAGSIVRASERLNLTPQTLSGQIGLLEDALGVPLFLRVGRRLELTETGRLALSYADEIFQIGNELE
EALRARPERHAIPFRVGVDDAVPKSIAYRLLTPAMGLASPVRIVCREDKLARLLVELAIQRVDLILADRPMPDEANVKGY
SHKLGNCGITFFAAPCLAKTFKKKWPHVLDAAPLLIPGKDAAIRLPLMRWFDVHQLRPHIVGEFDDSALMQAFGQAGIGI
FIAPSVIADEVQREHGVVVVGCTDEVTEQFYAISLERRLTHPAVVAINDTAHRELFATLAAS

Sequences:

>Translated_302_residues
MLNYKQLNYFWAVAKAGSIVRASERLNLTPQTLSGQIGLLEDALGVPLFLRVGRRLELTETGRLALSYADEIFQIGNELE
EALRARPERHAIPFRVGVDDAVPKSIAYRLLTPAMGLASPVRIVCREDKLARLLVELAIQRVDLILADRPMPDEANVKGY
SHKLGNCGITFFAAPCLAKTFKKKWPHVLDAAPLLIPGKDAAIRLPLMRWFDVHQLRPHIVGEFDDSALMQAFGQAGIGI
FIAPSVIADEVQREHGVVVVGCTDEVTEQFYAISLERRLTHPAVVAINDTAHRELFATLAAS
>Mature_302_residues
MLNYKQLNYFWAVAKAGSIVRASERLNLTPQTLSGQIGLLEDALGVPLFLRVGRRLELTETGRLALSYADEIFQIGNELE
EALRARPERHAIPFRVGVDDAVPKSIAYRLLTPAMGLASPVRIVCREDKLARLLVELAIQRVDLILADRPMPDEANVKGY
SHKLGNCGITFFAAPCLAKTFKKKWPHVLDAAPLLIPGKDAAIRLPLMRWFDVHQLRPHIVGEFDDSALMQAFGQAGIGI
FIAPSVIADEVQREHGVVVVGCTDEVTEQFYAISLERRLTHPAVVAINDTAHRELFATLAAS

Specific function: Plays a role in the positive regulation of nhaA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786202, Length=296, Percent_Identity=38.1756756756757, Blast_Score=204, Evalue=4e-54,
Organism=Escherichia coli, GI157672245, Length=70, Percent_Identity=45.7142857142857, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33377; Mature: 33377

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNYKQLNYFWAVAKAGSIVRASERLNLTPQTLSGQIGLLEDALGVPLFLRVGRRLELTE
CCCCHHHHHEEEEHHCCCEEEHHHHCCCCHHHHCCCCCHHHHHHCCHHHHHCCCEEEECC
TGRLALSYADEIFQIGNELEEALRARPERHAIPFRVGVDDAVPKSIAYRLLTPAMGLASP
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCC
VRIVCREDKLARLLVELAIQRVDLILADRPMPDEANVKGYSHKLGNCGITFFAAPCLAKT
HHEEECCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCHHCCCCCCCCHHHHHHHHHHH
FKKKWPHVLDAAPLLIPGKDAAIRLPLMRWFDVHQLRPHIVGEFDDSALMQAFGQAGIGI
HHHHCCHHHCCCCEEECCCCCEEEEHHHHHHHHHHCCCHHCCCCCHHHHHHHHHCCCCEE
FIAPSVIADEVQREHGVVVVGCTDEVTEQFYAISLERRLTHPAVVAINDTAHRELFATLA
EEEHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHH
AS
CC
>Mature Secondary Structure
MLNYKQLNYFWAVAKAGSIVRASERLNLTPQTLSGQIGLLEDALGVPLFLRVGRRLELTE
CCCCHHHHHEEEEHHCCCEEEHHHHCCCCHHHHCCCCCHHHHHHCCHHHHHCCCEEEECC
TGRLALSYADEIFQIGNELEEALRARPERHAIPFRVGVDDAVPKSIAYRLLTPAMGLASP
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCC
VRIVCREDKLARLLVELAIQRVDLILADRPMPDEANVKGYSHKLGNCGITFFAAPCLAKT
HHEEECCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCHHCCCCCCCCHHHHHHHHHHH
FKKKWPHVLDAAPLLIPGKDAAIRLPLMRWFDVHQLRPHIVGEFDDSALMQAFGQAGIGI
HHHHCCHHHCCCCEEECCCCCEEEEHHHHHHHHHHCCCHHCCCCCHHHHHHHHHCCCCEE
FIAPSVIADEVQREHGVVVVGCTDEVTEQFYAISLERRLTHPAVVAINDTAHRELFATLA
EEEHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHH
AS
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2429258; 1630901; 9278503; 3413113; 1316901; 8168494 [H]