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The map label for this gene is argB

Identifier: 82702245

GI number: 82702245

Start: 1287109

End: 1287990

Strand: Direct

Name: argB

Synonym: Nmul_A1116

Alternate gene names: 82702245

Gene position: 1287109-1287990 (Clockwise)

Preceding gene: 82702244

Following gene: 82702246

Centisome position: 40.42

GC content: 53.17

Gene sequence:

>882_bases
ATGCCATCTCAACCTTCTTCACAAGACAAAGCAAAAATTCTGGCTGAGGCACTACCTTATATCCAGCGCTTTCACGGGAA
AACCATCGTCATCAAGTATGGTGGCAACGCCATGACGGAAGAGAATCTCAAAAAGTGTTTCGCTCATGACGTAGCGCTGC
TGAAAGTGGTTGGCATGAACCCGGTAATCGTGCACGGGGGAGGTCCCCAGATCAACGATATGTTGAAGCGGGTCGGCAAG
CAGGGTGCCTTCATTCAGGGCATGCGTGTTACCGATGCCGAAACCATGGATGTCGTCGAGATGGTGCTGGGGCTGATCAA
CAAGGAAATCGTCAATCTCATCAATCAGCATGGGGGGCGTGCAGTCGGCCTGACAGGCAAGGATGGCAGCTTTATCCGCG
CAAAAAAAATGCTGGTGCGTGACAAGGAGAGAGGGCAAGAATGGGTTGATCTCGGCCAGGTCGGAGAAATCGAGGGCATC
GATCCCGCTCTGATCGAGTTGCTCGAGACCCGCGATTTCATCCCGGTAATCGCCCCGGTCGGGGTGGGCAGCCGCGGCGA
ATCCTATAATATCAATGCTGACCTAGTCGCCGGGGGACTGGCGCTGGTTTTGAACGCGGAAAAACTGATACTTCTTACCA
ACACACCGGGGGTGCTGAACAAGGATGGCAGTTTACTGACAGGGTTGACTGCACAGGAAGTGGATGAGCTAATTGCCGAT
GGCACCATTTCAGGGGGAATGATTCCCAAGATCAGTTCTGCCCTGGACGCAGTCAAGAGTGGTGTCAAAACATGCCACAT
CATCGATGGACGCGTCGAACACGGATTATTGCTCGAAGTGCTGACGGATGAGGGAGTTGGAACACTCATAAAGGCGAACT
GA

Upstream 100 bases:

>100_bases
CCTCCTATGTCATGTTAATGCCGTCGAGAGTATCGAATTTTTGAAACCCGGCAGCGCGCTACTCAAGGTAAAATAGCGCA
GAAAATTTCCTCAATAAGAC

Downstream 100 bases:

>100_bases
TTTACTGCTTCATGGCAAATCCGGGAGGCAAACTGTTACCCCTGGCAAATATTTCGTCCAGATCCTTATGGATTCCCTTT
GAGGAGGGAGTTGCCGGACG

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MPSQPSSQDKAKILAEALPYIQRFHGKTIVIKYGGNAMTEENLKKCFAHDVALLKVVGMNPVIVHGGGPQINDMLKRVGK
QGAFIQGMRVTDAETMDVVEMVLGLINKEIVNLINQHGGRAVGLTGKDGSFIRAKKMLVRDKERGQEWVDLGQVGEIEGI
DPALIELLETRDFIPVIAPVGVGSRGESYNINADLVAGGLALVLNAEKLILLTNTPGVLNKDGSLLTGLTAQEVDELIAD
GTISGGMIPKISSALDAVKSGVKTCHIIDGRVEHGLLLEVLTDEGVGTLIKAN

Sequences:

>Translated_293_residues
MPSQPSSQDKAKILAEALPYIQRFHGKTIVIKYGGNAMTEENLKKCFAHDVALLKVVGMNPVIVHGGGPQINDMLKRVGK
QGAFIQGMRVTDAETMDVVEMVLGLINKEIVNLINQHGGRAVGLTGKDGSFIRAKKMLVRDKERGQEWVDLGQVGEIEGI
DPALIELLETRDFIPVIAPVGVGSRGESYNINADLVAGGLALVLNAEKLILLTNTPGVLNKDGSLLTGLTAQEVDELIAD
GTISGGMIPKISSALDAVKSGVKTCHIIDGRVEHGLLLEVLTDEGVGTLIKAN
>Mature_292_residues
PSQPSSQDKAKILAEALPYIQRFHGKTIVIKYGGNAMTEENLKKCFAHDVALLKVVGMNPVIVHGGGPQINDMLKRVGKQ
GAFIQGMRVTDAETMDVVEMVLGLINKEIVNLINQHGGRAVGLTGKDGSFIRAKKMLVRDKERGQEWVDLGQVGEIEGID
PALIELLETRDFIPVIAPVGVGSRGESYNINADLVAGGLALVLNAEKLILLTNTPGVLNKDGSLLTGLTAQEVDELIADG
TISGGMIPKISSALDAVKSGVKTCHIIDGRVEHGLLLEVLTDEGVGTLIKAN

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

Organism=Escherichia coli, GI1789181, Length=285, Percent_Identity=30.5263157894737, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI145693208, Length=245, Percent_Identity=33.0612244897959, Blast_Score=97, Evalue=8e-22,
Organism=Saccharomyces cerevisiae, GI6320913, Length=269, Percent_Identity=30.4832713754647, Blast_Score=93, Evalue=6e-20,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ARGB_NITMU (Q2YA02)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_411811.1
- HSSP:   Q9HTN2
- ProteinModelPortal:   Q2YA02
- SMR:   Q2YA02
- STRING:   Q2YA02
- GeneID:   3785696
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A1116
- eggNOG:   COG0548
- HOGENOM:   HBG497643
- OMA:   MDIVEMV
- PhylomeDB:   Q2YA02
- ProtClustDB:   PRK00942
- BioCyc:   NMUL323848:NMUL_A1116-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00082_B
- InterPro:   IPR004662
- InterPro:   IPR001048
- InterPro:   IPR001057
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- PRINTS:   PR00474
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 31170; Mature: 31039

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: NA

Important sites: BINDING 89-89 BINDING 190-190

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSQPSSQDKAKILAEALPYIQRFHGKTIVIKYGGNAMTEENLKKCFAHDVALLKVVGMN
CCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHEECCC
PVIVHGGGPQINDMLKRVGKQGAFIQGMRVTDAETMDVVEMVLGLINKEIVNLINQHGGR
EEEEECCCCCHHHHHHHHCCCCCEEECEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCE
AVGLTGKDGSFIRAKKMLVRDKERGQEWVDLGQVGEIEGIDPALIELLETRDFIPVIAPV
EEEECCCCCCHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCHHHHHHHHHCCCCEEEEEC
GVGSRGESYNINADLVAGGLALVLNAEKLILLTNTPGVLNKDGSLLTGLTAQEVDELIAD
CCCCCCCCCCCCHHHHHCCEEEEEECCEEEEEECCCCCCCCCCCEEECCCHHHHHHHHHC
GTISGGMIPKISSALDAVKSGVKTCHIIDGRVEHGLLLEVLTDEGVGTLIKAN
CCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEECCCCCCEEEECC
>Mature Secondary Structure 
PSQPSSQDKAKILAEALPYIQRFHGKTIVIKYGGNAMTEENLKKCFAHDVALLKVVGMN
CCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHEECCC
PVIVHGGGPQINDMLKRVGKQGAFIQGMRVTDAETMDVVEMVLGLINKEIVNLINQHGGR
EEEEECCCCCHHHHHHHHCCCCCEEECEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCE
AVGLTGKDGSFIRAKKMLVRDKERGQEWVDLGQVGEIEGIDPALIELLETRDFIPVIAPV
EEEECCCCCCHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCHHHHHHHHHCCCCEEEEEC
GVGSRGESYNINADLVAGGLALVLNAEKLILLTNTPGVLNKDGSLLTGLTAQEVDELIAD
CCCCCCCCCCCCHHHHHCCEEEEEECCEEEEEECCCCCCCCCCCEEECCCHHHHHHHHHC
GTISGGMIPKISSALDAVKSGVKTCHIIDGRVEHGLLLEVLTDEGVGTLIKAN
CCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEECCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA