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The map label for this gene is htpG

Identifier: 82702238

GI number: 82702238

Start: 1277558

End: 1279477

Strand: Direct

Name: htpG

Synonym: Nmul_A1109

Alternate gene names: 82702238

Gene position: 1277558-1279477 (Clockwise)

Preceding gene: 82702233

Following gene: 82702240

Centisome position: 40.12

GC content: 52.6

Gene sequence:

>1920_bases
ATGGAAGCAACGGCTACAAAAGAACATTTGAATTTTCAGACCGAGGTCAAGCAACTCCTCAAGCTGATGATCCATTCCCT
GTATAGTAACAAGGAAATTTTCTTGCGCGAACTGATTTCCAACGCGTCGGATGCTGCCGACAAGCTGCGGTTCGAAGCCT
TGACCGACGGGGCGCTGTACGAATCTGATTCGGATCTGAAAATACGTGTAAGTTACGATAAGGAGGCACGCACCATTACT
GTTGCCGATAATGGCATCGGCATGTCGCGGCAGGAGGTGATAGACCATATCGGTACTATTGCCAAATCCGGCACACGAGA
ATTCTTCGACGCACTAACCGGCGACCAGGCCAAGGATGCGCACCTGATCGGCCAGTTCGGGGTGGGTTTTTATTCCGCAT
TCATTGTTGCTGACAAAGTGACGCTTACCACACGGCGCGCGGGCCTGACGCACGAACACGGGGTTCGCTGGGAATCGGGC
GGTGAGGGAGATTACACCCTTGAGACAATCGATAAACCTGGCCGTGGCACTGAGGTAACCTTGCATTTGCGCGAAGGAGA
GGATGAACTGCTCAATGGATGGCGGCTCCGCTCCATCATCCGCAAGTACTCGGACCATATCACCCTTCCCATCGTGATGA
AAAAAGAGGAATGGTCCCAGGAAAAAAATGAAAACACCGTTACGGAAGAAGACGAAACCATCAACCAGGCAAGTGCCTTG
TGGGCGCGGCCGAAAAACGAGATCAGCGAAGAGCAGTACAACGAATTCTACAAGCATGTCGCGCATGATTTCGAACCTCC
GCTGGCGTATGTGCATGCCAGGGTAGAGGGCAAGCAGGAATATACACAACTGCTCTACGTTCCTTCCCGCGCCCCGTTCG
ATCTGTATGACCGCGAATCCCGCCACGGCATCAAACTGTATGTCAGAAGAGTATTCATCATGGATGATGCCAAACAGTTG
CTGCCCAATTACCTGCGTTTCGTACGAGGAATAATAGATTCGAATGATCTGCCACTGAATGTTTCCCGCGAGATATTGCA
GGAATCGAAGGACATTGAAGCCATGCGGGCCGGCTCGGTGAAAAAGGTGCTGGGATTACTCGACGACCTGGCGCAAAGCG
AAACCGACGAAGGGAAGGCCAAATTCAAGACCTTCTGGAAGGAATTCGGACAGGTGATGAAAGAGGGGGTAGCGGAAGAC
TATGCCAACCGCGAGCGCATTGCCAAGCTGCTGCGCTTTGTTTCTACCCATTCCGATTCGGAAGAGCAGGACGTCTCCCT
GAGCGATTATGTGGGGCGCATGAAGGACGGGCAGGAGAAGATCTACTATGTCACCGCCGACAGTCTCACGGCGGCTAAAA
GCAGTCCACACCTCGAAATTTTCCGCAAGAAAGACATTGAAGTCATTCTACTGTTCGATCGCGTGGATGAGTGGCTGGTG
GCAAATCTGCCTGAGTTCGAGGGTAAACACCTGCAGTCCGTAGCAAAGGGCAGTCTCGATCTGGGTAAACTGGAGGACGA
GGCGGAGAAAAAGGAACAGGAAAAAGAAGCGGGTGAATACAAGGAACTCACCGAGAAAATAAAAGAAGTGCTCGGCGAGC
AGGTAAAGGATGTGCGGATCACCTTGCGTCTGACCGAGTCCCCCGCCTGCCTGGTGACGGAAACCCATGACATGAGCGGA
AATCTGGAGCGGCTGCTTAAGTCTGCCGGGCAGAAGGTCACGCATACCAAACCTATCCTGGAAATCAATCCGTACCATCC
CATGGTAGAGCGCCTGAAATCGGAGGAGACTCATTTCGCCGACTGGAGCCACATTTTGTTCGACCAAGCGCTGTTGGCCG
AGGGCGGGCAACTGGAGGATCCTGCCAGTTTTGTCAAACGTATCAATCAGTTGTTCCTGAGCACGGGGAGCAAGGAATAA

Upstream 100 bases:

>100_bases
CAGAGAGATAGCGCGGAAAATGATCGGTATGAAGCTTTTCAACTTGAAAATCCCGGATTTGCCCTTATTTATTTTATTGC
ATTTTTTTTGGAGGAAAACA

Downstream 100 bases:

>100_bases
TTGGCAGGATATTTCCCCAAACGGGCAGGAGATCGGAAAGCGGTATGAAAACGGGTATTTGATCAACCAAGCCTGAAAAT
CCGTTTGTACCCTCGGCCCT

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G

Number of amino acids: Translated: 639; Mature: 639

Protein sequence:

>639_residues
MEATATKEHLNFQTEVKQLLKLMIHSLYSNKEIFLRELISNASDAADKLRFEALTDGALYESDSDLKIRVSYDKEARTIT
VADNGIGMSRQEVIDHIGTIAKSGTREFFDALTGDQAKDAHLIGQFGVGFYSAFIVADKVTLTTRRAGLTHEHGVRWESG
GEGDYTLETIDKPGRGTEVTLHLREGEDELLNGWRLRSIIRKYSDHITLPIVMKKEEWSQEKNENTVTEEDETINQASAL
WARPKNEISEEQYNEFYKHVAHDFEPPLAYVHARVEGKQEYTQLLYVPSRAPFDLYDRESRHGIKLYVRRVFIMDDAKQL
LPNYLRFVRGIIDSNDLPLNVSREILQESKDIEAMRAGSVKKVLGLLDDLAQSETDEGKAKFKTFWKEFGQVMKEGVAED
YANRERIAKLLRFVSTHSDSEEQDVSLSDYVGRMKDGQEKIYYVTADSLTAAKSSPHLEIFRKKDIEVILLFDRVDEWLV
ANLPEFEGKHLQSVAKGSLDLGKLEDEAEKKEQEKEAGEYKELTEKIKEVLGEQVKDVRITLRLTESPACLVTETHDMSG
NLERLLKSAGQKVTHTKPILEINPYHPMVERLKSEETHFADWSHILFDQALLAEGGQLEDPASFVKRINQLFLSTGSKE

Sequences:

>Translated_639_residues
MEATATKEHLNFQTEVKQLLKLMIHSLYSNKEIFLRELISNASDAADKLRFEALTDGALYESDSDLKIRVSYDKEARTIT
VADNGIGMSRQEVIDHIGTIAKSGTREFFDALTGDQAKDAHLIGQFGVGFYSAFIVADKVTLTTRRAGLTHEHGVRWESG
GEGDYTLETIDKPGRGTEVTLHLREGEDELLNGWRLRSIIRKYSDHITLPIVMKKEEWSQEKNENTVTEEDETINQASAL
WARPKNEISEEQYNEFYKHVAHDFEPPLAYVHARVEGKQEYTQLLYVPSRAPFDLYDRESRHGIKLYVRRVFIMDDAKQL
LPNYLRFVRGIIDSNDLPLNVSREILQESKDIEAMRAGSVKKVLGLLDDLAQSETDEGKAKFKTFWKEFGQVMKEGVAED
YANRERIAKLLRFVSTHSDSEEQDVSLSDYVGRMKDGQEKIYYVTADSLTAAKSSPHLEIFRKKDIEVILLFDRVDEWLV
ANLPEFEGKHLQSVAKGSLDLGKLEDEAEKKEQEKEAGEYKELTEKIKEVLGEQVKDVRITLRLTESPACLVTETHDMSG
NLERLLKSAGQKVTHTKPILEINPYHPMVERLKSEETHFADWSHILFDQALLAEGGQLEDPASFVKRINQLFLSTGSKE
>Mature_639_residues
MEATATKEHLNFQTEVKQLLKLMIHSLYSNKEIFLRELISNASDAADKLRFEALTDGALYESDSDLKIRVSYDKEARTIT
VADNGIGMSRQEVIDHIGTIAKSGTREFFDALTGDQAKDAHLIGQFGVGFYSAFIVADKVTLTTRRAGLTHEHGVRWESG
GEGDYTLETIDKPGRGTEVTLHLREGEDELLNGWRLRSIIRKYSDHITLPIVMKKEEWSQEKNENTVTEEDETINQASAL
WARPKNEISEEQYNEFYKHVAHDFEPPLAYVHARVEGKQEYTQLLYVPSRAPFDLYDRESRHGIKLYVRRVFIMDDAKQL
LPNYLRFVRGIIDSNDLPLNVSREILQESKDIEAMRAGSVKKVLGLLDDLAQSETDEGKAKFKTFWKEFGQVMKEGVAED
YANRERIAKLLRFVSTHSDSEEQDVSLSDYVGRMKDGQEKIYYVTADSLTAAKSSPHLEIFRKKDIEVILLFDRVDEWLV
ANLPEFEGKHLQSVAKGSLDLGKLEDEAEKKEQEKEAGEYKELTEKIKEVLGEQVKDVRITLRLTESPACLVTETHDMSG
NLERLLKSAGQKVTHTKPILEINPYHPMVERLKSEETHFADWSHILFDQALLAEGGQLEDPASFVKRINQLFLSTGSKE

Specific function: Molecular chaperone. Has ATPase activity

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family

Homologues:

Organism=Homo sapiens, GI20149594, Length=682, Percent_Identity=39.5894428152493, Blast_Score=451, Evalue=1e-126,
Organism=Homo sapiens, GI4507677, Length=692, Percent_Identity=38.4393063583815, Blast_Score=440, Evalue=1e-123,
Organism=Homo sapiens, GI155722983, Length=644, Percent_Identity=34.9378881987578, Blast_Score=365, Evalue=1e-101,
Organism=Homo sapiens, GI154146191, Length=414, Percent_Identity=40.8212560386473, Blast_Score=294, Evalue=2e-79,
Organism=Homo sapiens, GI153792590, Length=416, Percent_Identity=40.625, Blast_Score=291, Evalue=1e-78,
Organism=Escherichia coli, GI1786679, Length=630, Percent_Identity=60.7936507936508, Blast_Score=778, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559162, Length=672, Percent_Identity=38.8392857142857, Blast_Score=469, Evalue=1e-132,
Organism=Caenorhabditis elegans, GI17542208, Length=671, Percent_Identity=39.1952309985097, Blast_Score=424, Evalue=1e-119,
Organism=Caenorhabditis elegans, GI115535205, Length=644, Percent_Identity=33.5403726708075, Blast_Score=331, Evalue=6e-91,
Organism=Caenorhabditis elegans, GI115535167, Length=431, Percent_Identity=35.2668213457077, Blast_Score=259, Evalue=3e-69,
Organism=Saccharomyces cerevisiae, GI6323840, Length=679, Percent_Identity=38.7334315169367, Blast_Score=472, Evalue=1e-134,
Organism=Saccharomyces cerevisiae, GI6325016, Length=683, Percent_Identity=38.3601756954612, Blast_Score=467, Evalue=1e-132,
Organism=Drosophila melanogaster, GI17647529, Length=687, Percent_Identity=37.8457059679767, Blast_Score=467, Evalue=1e-132,
Organism=Drosophila melanogaster, GI21357739, Length=689, Percent_Identity=38.0261248185776, Blast_Score=411, Evalue=1e-115,
Organism=Drosophila melanogaster, GI24586016, Length=649, Percent_Identity=32.6656394453005, Blast_Score=350, Evalue=2e-96,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): HTPG_NITMU (Q2YA09)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_411804.1
- ProteinModelPortal:   Q2YA09
- SMR:   Q2YA09
- STRING:   Q2YA09
- GeneID:   3785689
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A1109
- eggNOG:   COG0326
- HOGENOM:   HBG631012
- OMA:   AIYYITA
- PhylomeDB:   Q2YA09
- ProtClustDB:   PRK05218
- BioCyc:   NMUL323848:NMUL_A1109-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00505
- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568
- Gene3D:   G3DSA:3.30.565.10
- PANTHER:   PTHR11528
- PIRSF:   PIRSF002583
- PRINTS:   PR00775
- SMART:   SM00387

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90; SSF55874 ATP_bd_ATPase; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: NA

Molecular weight: Translated: 72908; Mature: 72908

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEATATKEHLNFQTEVKQLLKLMIHSLYSNKEIFLRELISNASDAADKLRFEALTDGALY
CCCCCCHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCEE
ESDSDLKIRVSYDKEARTITVADNGIGMSRQEVIDHIGTIAKSGTREFFDALTGDQAKDA
CCCCCEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCH
HLIGQFGVGFYSAFIVADKVTLTTRRAGLTHEHGVRWESGGEGDYTLETIDKPGRGTEVT
HHHHHHHHHHHHHHHHHCCEEEEEHHCCCCHHCCCCCCCCCCCCEEEEECCCCCCCCEEE
LHLREGEDELLNGWRLRSIIRKYSDHITLPIVMKKEEWSQEKNENTVTEEDETINQASAL
EEEECCCHHHHHHHHHHHHHHHHHCCEEEEEEECCHHHHHHCCCCCCCCCHHHHHHHHHH
WARPKNEISEEQYNEFYKHVAHDFEPPLAYVHARVEGKQEYTQLLYVPSRAPFDLYDRES
HCCCHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHEEECCCCCCCCCCCCCC
RHGIKLYVRRVFIMDDAKQLLPNYLRFVRGIIDSNDLPLNVSREILQESKDIEAMRAGSV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCH
KKVLGLLDDLAQSETDEGKAKFKTFWKEFGQVMKEGVAEDYANRERIAKLLRFVSTHSDS
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCC
EEQDVSLSDYVGRMKDGQEKIYYVTADSLTAAKSSPHLEIFRKKDIEVILLFDRVDEWLV
CHHCCCHHHHHHHHCCCCCEEEEEEECCHHHCCCCCCEEEEECCCCEEEEEEHHHHHHHH
ANLPEFEGKHLQSVAKGSLDLGKLEDEAEKKEQEKEAGEYKELTEKIKEVLGEQVKDVRI
CCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEE
TLRLTESPACLVTETHDMSGNLERLLKSAGQKVTHTKPILEINPYHPMVERLKSEETHFA
EEEEECCCCEEEEECCCCCCCHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHCCCCCCC
DWSHILFDQALLAEGGQLEDPASFVKRINQLFLSTGSKE
CHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MEATATKEHLNFQTEVKQLLKLMIHSLYSNKEIFLRELISNASDAADKLRFEALTDGALY
CCCCCCHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCEE
ESDSDLKIRVSYDKEARTITVADNGIGMSRQEVIDHIGTIAKSGTREFFDALTGDQAKDA
CCCCCEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCH
HLIGQFGVGFYSAFIVADKVTLTTRRAGLTHEHGVRWESGGEGDYTLETIDKPGRGTEVT
HHHHHHHHHHHHHHHHHCCEEEEEHHCCCCHHCCCCCCCCCCCCEEEEECCCCCCCCEEE
LHLREGEDELLNGWRLRSIIRKYSDHITLPIVMKKEEWSQEKNENTVTEEDETINQASAL
EEEECCCHHHHHHHHHHHHHHHHHCCEEEEEEECCHHHHHHCCCCCCCCCHHHHHHHHHH
WARPKNEISEEQYNEFYKHVAHDFEPPLAYVHARVEGKQEYTQLLYVPSRAPFDLYDRES
HCCCHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHEEECCCCCCCCCCCCCC
RHGIKLYVRRVFIMDDAKQLLPNYLRFVRGIIDSNDLPLNVSREILQESKDIEAMRAGSV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCH
KKVLGLLDDLAQSETDEGKAKFKTFWKEFGQVMKEGVAEDYANRERIAKLLRFVSTHSDS
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCC
EEQDVSLSDYVGRMKDGQEKIYYVTADSLTAAKSSPHLEIFRKKDIEVILLFDRVDEWLV
CHHCCCHHHHHHHHCCCCCEEEEEEECCHHHCCCCCCEEEEECCCCEEEEEEHHHHHHHH
ANLPEFEGKHLQSVAKGSLDLGKLEDEAEKKEQEKEAGEYKELTEKIKEVLGEQVKDVRI
CCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEE
TLRLTESPACLVTETHDMSGNLERLLKSAGQKVTHTKPILEINPYHPMVERLKSEETHFA
EEEEECCCCEEEEECCCCCCCHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHCCCCCCC
DWSHILFDQALLAEGGQLEDPASFVKRINQLFLSTGSKE
CHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA