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The map label for this gene is czcC [H]

Identifier: 82702240

GI number: 82702240

Start: 1280908

End: 1282386

Strand: Direct

Name: czcC [H]

Synonym: Nmul_A1111

Alternate gene names: 82702240

Gene position: 1280908-1282386 (Clockwise)

Preceding gene: 82702238

Following gene: 82702241

Centisome position: 40.23

GC content: 61.46

Gene sequence:

>1479_bases
ATGCATATATCACGTCTTTGCCGTATTTTGTCGACCCTGATTCTTGTTTCGCCACTCCCGCCGGCCTTGGCTCTGGAGCC
TTCGACGATTCCTGCCATTACCCCGCCTCCGGCGCTTCCGCCAGCTATGGCGCCCGCCCCCGCGCCCCCTGTCATGCCTG
CACCCCGGTCGCCGGCGCTGCCGCCGGCCACTGCACCCGGTCCAACCGTGCCCGGACCGGCAACGGGACGGGTACCCGGC
TTGCTGGCTCCTGCCGCACCGGGTCCGACCATGCCAACGCCAACGACGCCACCTTCCCAAGTTCTCACCATTGAGGAGTT
GCAGCGACTGGGATTGAGGGCCAATGGCCTGGTGCAGGCAGCCAATTTCCAAATAAAAGCTGCGGAAGCGGGTGTGGTGG
GTGCTTCGGCTTACCCCAACCCGCAACTCACCTTCATGGCAGGCCCCCAGCATGCGCGGGTCGTGCCGCAGGCCTTGCCT
GCAAACAGCCACCGTCAATTTACTATATCTCAGACGATCGAGAATCCGTTCCTGCGGAGCGCGCGCATCGACTCGGCAGA
AGCAGGAGTGGATGCCAGTCATGCAGGCCTGGAGCAGGTGAGGGCCGATTTGGCGGCGCAACTGCGGGTTGCCGCCTATG
AACTGATCCTGCGTCAGGAAGTGGCGCGAGTGGAGGCAAGCGTTTCCGATTTGATGGAGGAAATACGTCGCCGCGTCAGG
ATGCGTGTCGATGTGGGGGAGGCGCCGCGCTTCGAACTGATCAGGGCCGAAACGGAAGTTCTGGCCGCAGCTTCGCGTAA
GGAAGCGGCGCAGTTGAATGCGCAGAGGGCTCGCATAGCCCTGATTCAGCTTACCGCTGGTGCTTTGCAGCCTGATTTCC
AGGTAACGGGGTCGCTGACAGAGTCCGTAAACCTTCCTCCTCTCGAAGAACTGCGCGAAACTGTGCCTGCAGTCAATCCC
GAGGTGACGCGCCTGGAGGCCGAATGGAAGCGGGCCCGGCGGCGAATCGACCAGGAACGTGCGGCGGTGCTGCCATCGTT
AACGGTATTGCTCAGCAATTTTCAGGAGGCGCAATACACCTCGAACCTGGCAGGCGTAAACGTAACCATCCCTTTGTTTT
ATCGGCGGCGTGGGGAGATCAACGCCGCTGTAGCGGATTCCGAGCGGGCGCGCGGGATACTGGAGTTTCGGCGCTTCGAA
ATAGGGCAGTTGCTTGAATCCGCCTGGCAGGCCAAGCAGATCGCCCAGCGCAGAGTGGACATGTTCGAAGGCGGATTGGT
GAAGGAAGCGGAAAACGCTCTGGAAATTGCGCAGGCAGCCTATCGGTTTGGCGAACGGGGCCTGATCGAAGTGCTCGATA
CGCAGCGCGTGCTGCGCGGCGTGCTTTCGGATCTCCTGCAGGCGCGCTTCGATTTGCAGGCTGCGGTTACAGAGATCGAT
CGCCTGCGAGCCTATTATCCCAAGGAAGACCTCGAATGA

Upstream 100 bases:

>100_bases
TGGCGTTCTTGTTCCGGTTGTTGAAACCCTCTTTCCCGCAGCCTCAACGTATGCAGTGCGATCGTTCAGGCGTCGCCTCG
AAGAATTCAACGGGTAGTAC

Downstream 100 bases:

>100_bases
AAATCACCCTGCCGTTAATCGGCATCATGCTTGTATTGCTTATTGCTGGTTGCGGGGGCGGGAAGCCTGCAGACAAGGAG
GAGACTGTCAAAGAAGAGCC

Product: Outer membrane efflux protein

Products: NA

Alternate protein names: Cation efflux system protein CzcC [H]

Number of amino acids: Translated: 492; Mature: 492

Protein sequence:

>492_residues
MHISRLCRILSTLILVSPLPPALALEPSTIPAITPPPALPPAMAPAPAPPVMPAPRSPALPPATAPGPTVPGPATGRVPG
LLAPAAPGPTMPTPTTPPSQVLTIEELQRLGLRANGLVQAANFQIKAAEAGVVGASAYPNPQLTFMAGPQHARVVPQALP
ANSHRQFTISQTIENPFLRSARIDSAEAGVDASHAGLEQVRADLAAQLRVAAYELILRQEVARVEASVSDLMEEIRRRVR
MRVDVGEAPRFELIRAETEVLAAASRKEAAQLNAQRARIALIQLTAGALQPDFQVTGSLTESVNLPPLEELRETVPAVNP
EVTRLEAEWKRARRRIDQERAAVLPSLTVLLSNFQEAQYTSNLAGVNVTIPLFYRRRGEINAAVADSERARGILEFRRFE
IGQLLESAWQAKQIAQRRVDMFEGGLVKEAENALEIAQAAYRFGERGLIEVLDTQRVLRGVLSDLLQARFDLQAAVTEID
RLRAYYPKEDLE

Sequences:

>Translated_492_residues
MHISRLCRILSTLILVSPLPPALALEPSTIPAITPPPALPPAMAPAPAPPVMPAPRSPALPPATAPGPTVPGPATGRVPG
LLAPAAPGPTMPTPTTPPSQVLTIEELQRLGLRANGLVQAANFQIKAAEAGVVGASAYPNPQLTFMAGPQHARVVPQALP
ANSHRQFTISQTIENPFLRSARIDSAEAGVDASHAGLEQVRADLAAQLRVAAYELILRQEVARVEASVSDLMEEIRRRVR
MRVDVGEAPRFELIRAETEVLAAASRKEAAQLNAQRARIALIQLTAGALQPDFQVTGSLTESVNLPPLEELRETVPAVNP
EVTRLEAEWKRARRRIDQERAAVLPSLTVLLSNFQEAQYTSNLAGVNVTIPLFYRRRGEINAAVADSERARGILEFRRFE
IGQLLESAWQAKQIAQRRVDMFEGGLVKEAENALEIAQAAYRFGERGLIEVLDTQRVLRGVLSDLLQARFDLQAAVTEID
RLRAYYPKEDLE
>Mature_492_residues
MHISRLCRILSTLILVSPLPPALALEPSTIPAITPPPALPPAMAPAPAPPVMPAPRSPALPPATAPGPTVPGPATGRVPG
LLAPAAPGPTMPTPTTPPSQVLTIEELQRLGLRANGLVQAANFQIKAAEAGVVGASAYPNPQLTFMAGPQHARVVPQALP
ANSHRQFTISQTIENPFLRSARIDSAEAGVDASHAGLEQVRADLAAQLRVAAYELILRQEVARVEASVSDLMEEIRRRVR
MRVDVGEAPRFELIRAETEVLAAASRKEAAQLNAQRARIALIQLTAGALQPDFQVTGSLTESVNLPPLEELRETVPAVNP
EVTRLEAEWKRARRRIDQERAAVLPSLTVLLSNFQEAQYTSNLAGVNVTIPLFYRRRGEINAAVADSERARGILEFRRFE
IGQLLESAWQAKQIAQRRVDMFEGGLVKEAENALEIAQAAYRFGERGLIEVLDTQRVLRGVLSDLLQARFDLQAAVTEID
RLRAYYPKEDLE

Specific function: CzcC protein appears to modify the specificity of the system, perhaps by acting on the CzcB protein. When the CzcC protein is added to CzcA and CzcB, the efflux system gains specificity for cadmium and cobalt [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 53424; Mature: 53424

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHISRLCRILSTLILVSPLPPALALEPSTIPAITPPPALPPAMAPAPAPPVMPAPRSPAL
CCHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PPATAPGPTVPGPATGRVPGLLAPAAPGPTMPTPTTPPSQVLTIEELQRLGLRANGLVQA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHEEEHHHHHHCCCCCCCEEEE
ANFQIKAAEAGVVGASAYPNPQLTFMAGPQHARVVPQALPANSHRQFTISQTIENPFLRS
CCEEEEECCCCEEECCCCCCCCEEEEECCCCHHHCHHHCCCCCCCEEEHHHHHCCHHHHH
ARIDSAEAGVDASHAGLEQVRADLAAQLRVAAYELILRQEVARVEASVSDLMEEIRRRVR
HCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MRVDVGEAPRFELIRAETEVLAAASRKEAAQLNAQRARIALIQLTAGALQPDFQVTGSLT
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCEECCCHH
ESVNLPPLEELRETVPAVNPEVTRLEAEWKRARRRIDQERAAVLPSLTVLLSNFQEAQYT
CCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SNLAGVNVTIPLFYRRRGEINAAVADSERARGILEFRRFEIGQLLESAWQAKQIAQRRVD
HCCCCCEEEEEEEEECCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MFEGGLVKEAENALEIAQAAYRFGERGLIEVLDTQRVLRGVLSDLLQARFDLQAAVTEID
HHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLRAYYPKEDLE
HHHHHCCCCCCC
>Mature Secondary Structure
MHISRLCRILSTLILVSPLPPALALEPSTIPAITPPPALPPAMAPAPAPPVMPAPRSPAL
CCHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PPATAPGPTVPGPATGRVPGLLAPAAPGPTMPTPTTPPSQVLTIEELQRLGLRANGLVQA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHEEEHHHHHHCCCCCCCEEEE
ANFQIKAAEAGVVGASAYPNPQLTFMAGPQHARVVPQALPANSHRQFTISQTIENPFLRS
CCEEEEECCCCEEECCCCCCCCEEEEECCCCHHHCHHHCCCCCCCEEEHHHHHCCHHHHH
ARIDSAEAGVDASHAGLEQVRADLAAQLRVAAYELILRQEVARVEASVSDLMEEIRRRVR
HCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MRVDVGEAPRFELIRAETEVLAAASRKEAAQLNAQRARIALIQLTAGALQPDFQVTGSLT
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCEECCCHH
ESVNLPPLEELRETVPAVNPEVTRLEAEWKRARRRIDQERAAVLPSLTVLLSNFQEAQYT
CCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SNLAGVNVTIPLFYRRRGEINAAVADSERARGILEFRRFEIGQLLESAWQAKQIAQRRVD
HCCCCCEEEEEEEEECCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MFEGGLVKEAENALEIAQAAYRFGERGLIEVLDTQRVLRGVLSDLLQARFDLQAAVTEID
HHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLRAYYPKEDLE
HHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2678100; 7766206 [H]