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The map label for this gene is nuoC

Identifier: 82702222

GI number: 82702222

Start: 1258768

End: 1259385

Strand: Direct

Name: nuoC

Synonym: Nmul_A1093

Alternate gene names: 82702222

Gene position: 1258768-1259385 (Clockwise)

Preceding gene: 82702221

Following gene: 82702223

Centisome position: 39.53

GC content: 54.37

Gene sequence:

>618_bases
ATGTCGTCCACTCGTCTGGAAACGCTCGCCCTTTGCCTTCAGAATGTGTTGGCGGATAAACTTGCCAACGTCGATCAGCA
ACTGGACCAGCTCATCATTACGGTGTCTCCGGTTAACCTGTTGCCGGTGATGAGCGTCTTGCGCGACCATCCCGAACTGG
GTTTCGAGATGCTCATCGACCTGTGTGGAGTGGATTACTCCATCTATGGAGTAGAGCCCACTTCGGAGCAGGGACGTGAG
GGCAAACGCTTCGCTGTCGTTTATCACCTGCTTTCGATCCGGCATAACCGCAGAGTGCGTGTAAAGGCATTCCCCGAGGA
TGACGAATTTCCGGTTGTGGTCTCGGTAATAGATATATGGCCTTCCGCCAACTGGTTTGAACGCGAAGCATTCGATCTTT
ATGGCATCGTGTTCACCGGTCACCCCGACCTGCGCCGTATCCTCACGGATTACGGATTTATCGGTAACCCATTCCGCAAG
GATTTTCCGCTCAGTGGCAATGTGGAGATGCGCTACGATCCCGACCAACAGCGGGTCGTCTATCAGCCGGTCACCATAGA
ACCGCGCCAGATCACGCCGCGCGTTATCCGGGAAGAGCATTATGGGGACTCTGAATGA

Upstream 100 bases:

>100_bases
TTCCCGGTTGCCCGCCTACCGCAGAAGCCCTGCTGTACGGCATTATCCAGCTCCAGAACAAGATCCATCGCACCAATACC
ATCGCTCGTTAGGCTCATCT

Downstream 100 bases:

>100_bases
GATTTTTGTGGGCTGTTAACGATGGCTGAGATACGTAATTACACGATGAACTTCGGCCCGCAGCATCCGGCCGCCCACGG
TGTCTTGCGACTGGTGCTGG

Product: NADH dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C

Number of amino acids: Translated: 205; Mature: 204

Protein sequence:

>205_residues
MSSTRLETLALCLQNVLADKLANVDQQLDQLIITVSPVNLLPVMSVLRDHPELGFEMLIDLCGVDYSIYGVEPTSEQGRE
GKRFAVVYHLLSIRHNRRVRVKAFPEDDEFPVVVSVIDIWPSANWFEREAFDLYGIVFTGHPDLRRILTDYGFIGNPFRK
DFPLSGNVEMRYDPDQQRVVYQPVTIEPRQITPRVIREEHYGDSE

Sequences:

>Translated_205_residues
MSSTRLETLALCLQNVLADKLANVDQQLDQLIITVSPVNLLPVMSVLRDHPELGFEMLIDLCGVDYSIYGVEPTSEQGRE
GKRFAVVYHLLSIRHNRRVRVKAFPEDDEFPVVVSVIDIWPSANWFEREAFDLYGIVFTGHPDLRRILTDYGFIGNPFRK
DFPLSGNVEMRYDPDQQRVVYQPVTIEPRQITPRVIREEHYGDSE
>Mature_204_residues
SSTRLETLALCLQNVLADKLANVDQQLDQLIITVSPVNLLPVMSVLRDHPELGFEMLIDLCGVDYSIYGVEPTSEQGREG
KRFAVVYHLLSIRHNRRVRVKAFPEDDEFPVVVSVIDIWPSANWFEREAFDLYGIVFTGHPDLRRILTDYGFIGNPFRKD
FPLSGNVEMRYDPDQQRVVYQPVTIEPRQITPRVIREEHYGDSE

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family

Homologues:

Organism=Homo sapiens, GI4758788, Length=159, Percent_Identity=47.1698113207547, Blast_Score=152, Evalue=2e-37,
Organism=Escherichia coli, GI145693162, Length=133, Percent_Identity=39.0977443609023, Blast_Score=90, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71990788, Length=155, Percent_Identity=45.1612903225806, Blast_Score=137, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI32563621, Length=155, Percent_Identity=45.1612903225806, Blast_Score=137, Evalue=5e-33,
Organism=Drosophila melanogaster, GI24656494, Length=158, Percent_Identity=45.5696202531646, Blast_Score=148, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOC_NITMU (Q2YA25)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_411788.1
- ProteinModelPortal:   Q2YA25
- SMR:   Q2YA25
- STRING:   Q2YA25
- GeneID:   3784708
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A1093
- eggNOG:   COG0852
- HOGENOM:   HBG727675
- OMA:   VFAPDDD
- ProtClustDB:   PRK06074
- BioCyc:   NMUL323848:NMUL_A1093-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01357
- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581
- TIGRFAMs:   TIGR01961

Pfam domain/function: PF00329 Complex1_30kDa

EC number: =1.6.99.5

Molecular weight: Translated: 23649; Mature: 23518

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSTRLETLALCLQNVLADKLANVDQQLDQLIITVSPVNLLPVMSVLRDHPELGFEMLID
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHCCCCHHHHHHHH
LCGVDYSIYGVEPTSEQGREGKRFAVVYHLLSIRHNRRVRVKAFPEDDEFPVVVSVIDIW
HHCCCEEEEECCCCHHCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEEEECC
PSANWFEREAFDLYGIVFTGHPDLRRILTDYGFIGNPFRKDFPLSGNVEMRYDPDQQRVV
CCCCCCHHCCEEEEEEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCEEE
YQPVTIEPRQITPRVIREEHYGDSE
ECCCCCCCHHCCHHHHHHCCCCCCC
>Mature Secondary Structure 
SSTRLETLALCLQNVLADKLANVDQQLDQLIITVSPVNLLPVMSVLRDHPELGFEMLID
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHCCCCHHHHHHHH
LCGVDYSIYGVEPTSEQGREGKRFAVVYHLLSIRHNRRVRVKAFPEDDEFPVVVSVIDIW
HHCCCEEEEECCCCHHCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEEEECC
PSANWFEREAFDLYGIVFTGHPDLRRILTDYGFIGNPFRKDFPLSGNVEMRYDPDQQRVV
CCCCCCHHCCEEEEEEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCEEE
YQPVTIEPRQITPRVIREEHYGDSE
ECCCCCCCHHCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA