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The map label for this gene is tldD [H]

Identifier: 82702184

GI number: 82702184

Start: 1214655

End: 1216115

Strand: Reverse

Name: tldD [H]

Synonym: Nmul_A1055

Alternate gene names: 82702184

Gene position: 1216115-1214655 (Counterclockwise)

Preceding gene: 82702185

Following gene: 82702179

Centisome position: 38.19

GC content: 55.44

Gene sequence:

>1461_bases
ATGATTACAGAACAGACTATCCAGGTTAACGATCTTTTCGCGACGGCCAACAATTGTCTGCTTGCACCTCATGAACTGGA
TGCAACCGGGTTACAGAACGTGTTCGGCCAGCTGCTTGCGCACCGCATCGATTATGCCGACCTGTATTTTCAGTATAGCC
GAGCCGAGGGCTGGGCTCTGGAAGAAGGCATAGTCAAATCCGGCAGCTTTAATATCGATCAAGGCGTGGGTGTACGCGCA
GTCAGCGGAGATAAGACCGCCTTTGCGTATTCGGACGACATCAGCATGCCTGCGCTGGTGTCTGCCGCACAGGCTACGCG
AGCCATCGCTCGCCATGGCGTCACGCAATCGGTGCAAGTTGTCAAACGCAGCAAGGGGCGGGAGCTTTATCTGCCTGAAG
ACCCGATTGCCAGCCTCAAGGATACGGACAAGGTGGCTTTGCTCGAAAAGCTCGAAAGTTATGCGCGGGCGCTGGACAAA
CGTGTTATCCAAGTCATGGCTTCCCTCTCAGGGGAATACGAAGTGGTTCTCGTTGCCCGCAGTGATGGTCTTCTGGCAGC
CGATGTGCGCCCGCTTGTGCGTCTCTCATTGCAGGTTATTGCCGAGGAAAACGGCAACCGTGAGCAAGGAGTTGCAGGAG
GAGGAGGACGCTTCGACTATGCATACTTCACGGATGACGTGCTGCGCGACTATGCTGCAAAAGCGGTTCACCAAGCGGTT
GTCAACCTGCATGCAAAACCGGCGCCTGCCGGAACCATGACTGTGGTGCTCGGTTCGGGTTGGCCGGGAATACTGTTGCA
TGAGGCCATTGGCCACGGGTTGGAAGGAGACTTCAACCGCAAAGGGAGTTCCGCATTTGCGGGTCGAATCGGCGAACGCG
TGGCTGCACCGGGAGTGACGGTGGTGGATGATGGCACTATTGCACGCCGGCGGGGCTCGCTCAACGTCGATGACGAAGGG
AACCCCACCCAGTGCACAATGCTGATCGAAAACGGAATACTCAAGGGTTATTTGCAGGACAGCCTGAATGCACGGCTGAT
GAACGTTCCCGTCACAGGAAATGCAAGACGCGAATCATTTGCGCACATTCCCATGCCGCGCATGACGAATACTTATATGC
TGAATGGGGACAAAACTCCGGAAGAAATCATCGCTTCCGTGAAGCACGGATTATATGCGGTCAATTTCGGCGGGGGACAG
GTAGATATCACCAGCGGAAAATTCGTATTTTCGGCTGCGGAAGCCTACATGATCGAAAATGGAAAAATTTCGTATCCGGT
GAAGGGCGCCACTCTCATTGGCAATGGTCCTGATATACTCACCCGCGTTTCGATGATCGGCAACGATCTGTCGCTTGATC
CCGGGGTCGGGACGTGTGGCAAGGAAGGCCAGAGCGTGCCCGTAGGCGTGGGTCAACCCACCCTTCGCATAGATGGACTG
ACGGTGGGAGGAACAGCGTAG

Upstream 100 bases:

>100_bases
AGGCGAGCTTGCGCAGCAGCCTGCCCGCCTTGAATCACCGCACGCTGCGTTACTTTTGAATTCCGTTGAACCTTGTTCTC
CTTCTCCCCCACTAACTACC

Downstream 100 bases:

>100_bases
CCTCGGGCAGTATTCCCTATCAGCCATTGAAGCAGCCGATTTGAAGCGGGGGTTTCACGGCAAGATGACGAGCGCCCCCT
ATACGTTCCCGTCAGGTTTC

Product: peptidase U62, modulator of DNA gyrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 486; Mature: 486

Protein sequence:

>486_residues
MITEQTIQVNDLFATANNCLLAPHELDATGLQNVFGQLLAHRIDYADLYFQYSRAEGWALEEGIVKSGSFNIDQGVGVRA
VSGDKTAFAYSDDISMPALVSAAQATRAIARHGVTQSVQVVKRSKGRELYLPEDPIASLKDTDKVALLEKLESYARALDK
RVIQVMASLSGEYEVVLVARSDGLLAADVRPLVRLSLQVIAEENGNREQGVAGGGGRFDYAYFTDDVLRDYAAKAVHQAV
VNLHAKPAPAGTMTVVLGSGWPGILLHEAIGHGLEGDFNRKGSSAFAGRIGERVAAPGVTVVDDGTIARRRGSLNVDDEG
NPTQCTMLIENGILKGYLQDSLNARLMNVPVTGNARRESFAHIPMPRMTNTYMLNGDKTPEEIIASVKHGLYAVNFGGGQ
VDITSGKFVFSAAEAYMIENGKISYPVKGATLIGNGPDILTRVSMIGNDLSLDPGVGTCGKEGQSVPVGVGQPTLRIDGL
TVGGTA

Sequences:

>Translated_486_residues
MITEQTIQVNDLFATANNCLLAPHELDATGLQNVFGQLLAHRIDYADLYFQYSRAEGWALEEGIVKSGSFNIDQGVGVRA
VSGDKTAFAYSDDISMPALVSAAQATRAIARHGVTQSVQVVKRSKGRELYLPEDPIASLKDTDKVALLEKLESYARALDK
RVIQVMASLSGEYEVVLVARSDGLLAADVRPLVRLSLQVIAEENGNREQGVAGGGGRFDYAYFTDDVLRDYAAKAVHQAV
VNLHAKPAPAGTMTVVLGSGWPGILLHEAIGHGLEGDFNRKGSSAFAGRIGERVAAPGVTVVDDGTIARRRGSLNVDDEG
NPTQCTMLIENGILKGYLQDSLNARLMNVPVTGNARRESFAHIPMPRMTNTYMLNGDKTPEEIIASVKHGLYAVNFGGGQ
VDITSGKFVFSAAEAYMIENGKISYPVKGATLIGNGPDILTRVSMIGNDLSLDPGVGTCGKEGQSVPVGVGQPTLRIDGL
TVGGTA
>Mature_486_residues
MITEQTIQVNDLFATANNCLLAPHELDATGLQNVFGQLLAHRIDYADLYFQYSRAEGWALEEGIVKSGSFNIDQGVGVRA
VSGDKTAFAYSDDISMPALVSAAQATRAIARHGVTQSVQVVKRSKGRELYLPEDPIASLKDTDKVALLEKLESYARALDK
RVIQVMASLSGEYEVVLVARSDGLLAADVRPLVRLSLQVIAEENGNREQGVAGGGGRFDYAYFTDDVLRDYAAKAVHQAV
VNLHAKPAPAGTMTVVLGSGWPGILLHEAIGHGLEGDFNRKGSSAFAGRIGERVAAPGVTVVDDGTIARRRGSLNVDDEG
NPTQCTMLIENGILKGYLQDSLNARLMNVPVTGNARRESFAHIPMPRMTNTYMLNGDKTPEEIIASVKHGLYAVNFGGGQ
VDITSGKFVFSAAEAYMIENGKISYPVKGATLIGNGPDILTRVSMIGNDLSLDPGVGTCGKEGQSVPVGVGQPTLRIDGL
TVGGTA

Specific function: Suppresses the inhibitory activity of the carbon storage regulator (CsrA) [H]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=472, Percent_Identity=61.4406779661017, Blast_Score=563, Evalue=1e-162,
Organism=Escherichia coli, GI1790682, Length=412, Percent_Identity=24.2718446601942, Blast_Score=88, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 51703; Mature: 51703

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITEQTIQVNDLFATANNCLLAPHELDATGLQNVFGQLLAHRIDYADLYFQYSRAEGWAL
CCCCCEEEEEEEEEECCCCEECCCCCCHHHHHHHHHHHHHHHCCHHHEEEEECCCCCCCH
EEGIVKSGSFNIDQGVGVRAVSGDKTAFAYSDDISMPALVSAAQATRAIARHGVTQSVQV
HHCCCCCCCCCCCCCCCEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHH
VKRSKGRELYLPEDPIASLKDTDKVALLEKLESYARALDKRVIQVMASLSGEYEVVLVAR
HHHCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEC
SDGLLAADVRPLVRLSLQVIAEENGNREQGVAGGGGRFDYAYFTDDVLRDYAAKAVHQAV
CCCEEEHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHH
VNLHAKPAPAGTMTVVLGSGWPGILLHEAIGHGLEGDFNRKGSSAFAGRIGERVAAPGVT
HHCCCCCCCCCEEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCE
VVDDGTIARRRGSLNVDDEGNPTQCTMLIENGILKGYLQDSLNARLMNVPVTGNARRESF
EEECCCEECCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHCCCCEEEEECCCCCCCCCCC
AHIPMPRMTNTYMLNGDKTPEEIIASVKHGLYAVNFGGGQVDITSGKFVFSAAEAYMIEN
CCCCCCCCCCEEEECCCCCHHHHHHHHHCCEEEEEECCCEEEEECCCEEEEECEEEEEEC
GKISYPVKGATLIGNGPDILTRVSMIGNDLSLDPGVGTCGKEGQSVPVGVGQPTLRIDGL
CEEECCCCCEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCE
TVGGTA
EECCCC
>Mature Secondary Structure
MITEQTIQVNDLFATANNCLLAPHELDATGLQNVFGQLLAHRIDYADLYFQYSRAEGWAL
CCCCCEEEEEEEEEECCCCEECCCCCCHHHHHHHHHHHHHHHCCHHHEEEEECCCCCCCH
EEGIVKSGSFNIDQGVGVRAVSGDKTAFAYSDDISMPALVSAAQATRAIARHGVTQSVQV
HHCCCCCCCCCCCCCCCEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHH
VKRSKGRELYLPEDPIASLKDTDKVALLEKLESYARALDKRVIQVMASLSGEYEVVLVAR
HHHCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEC
SDGLLAADVRPLVRLSLQVIAEENGNREQGVAGGGGRFDYAYFTDDVLRDYAAKAVHQAV
CCCEEEHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHH
VNLHAKPAPAGTMTVVLGSGWPGILLHEAIGHGLEGDFNRKGSSAFAGRIGERVAAPGVT
HHCCCCCCCCCEEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCE
VVDDGTIARRRGSLNVDDEGNPTQCTMLIENGILKGYLQDSLNARLMNVPVTGNARRESF
EEECCCEECCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHCCCCEEEEECCCCCCCCCCC
AHIPMPRMTNTYMLNGDKTPEEIIASVKHGLYAVNFGGGQVDITSGKFVFSAAEAYMIEN
CCCCCCCCCCEEEECCCCCHHHHHHHHHCCEEEEEECCCEEEEECCCEEEEECEEEEEEC
GKISYPVKGATLIGNGPDILTRVSMIGNDLSLDPGVGTCGKEGQSVPVGVGQPTLRIDGL
CEEECCCCCEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCE
TVGGTA
EECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]