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The map label for this gene is htpX [H]

Identifier: 82702163

GI number: 82702163

Start: 1195316

End: 1196197

Strand: Direct

Name: htpX [H]

Synonym: Nmul_A1034

Alternate gene names: 82702163

Gene position: 1195316-1196197 (Clockwise)

Preceding gene: 82702162

Following gene: 82702166

Centisome position: 37.54

GC content: 54.99

Gene sequence:

>882_bases
ATGAAGCGAATTTTTCTATTTGTAGTTACCAATCTGGCCATCTTGCTGGTGCTGAGCATCACATTGCGCTTGTTGGGTGT
TGATCGCATGCTTGACGAGCAGGGTGTGGGTATCAATTACAATTCACTGCTTGTCATGGCGGCAGTAATCGGTTTTGGCG
GTTCGCTGATTTCGCTGGCCATGTCCAAGTGGAGTGCGAAACGCATGACGGGTGCGGTCGTGATCGAGCAACCTTCCGAT
CCGACCGAGCGCTGGCTGGTGGAAACTGTCCGGCGGCAGGCTGAGCGCGTGGGTATCGGTATGCCGGAAGTGGCGATCTA
CGAGGCACCGGACATGAATGCCTTTGCAACCGGCATGAACCGCAACGAGGCATTGGTGGCGGTAAGTACCGGCTTGCTTC
AGGCTATGACAAAAGATGAAATCGAGGGAGTGCTGGCGCATGAAATAAGCCATGTTGCCAACGGCGATATGGTGACACTT
GCGCTGATTCAGGGTGTCGTCAATACCTTCGTGATTTTTTTATCGAGAGTCATCGGCCATTTCGTGGACAGGGTCATATT
CAAAACCGAGCGGGAGTACGGCCCCGCCTTCATGGTTACCACACTGATCGCCCAAATGGTACTTGGGATATTGGCGAGCA
TCATTGTAATGTGGTTCAGCCGCCAGCGTGAGTTTCGTGCGGATGCGGGTGGAGCGCAGCTGGCTGGACGCAACAAAATG
ATCGCAGCGCTTGAACGCCTGCAACGCCGGCACGAGCCCTCCCAGTTGCCGGAGCGGTTGGAAGCATTCGGTATTTCCGG
AGGGGAAGGGGGTCTCAGAACCCTGTTCATGTCTCATCCGCCTCTTGAAGTGCGTATTGCAGCGCTTCGCGCGATGACCT
GA

Upstream 100 bases:

>100_bases
TATTGCGAGGAGCAAGGTTCTGCCTGCAGCGTCTCCTTGAAAAATTGAACTCCCATCCCTATATATGATCCATCTCTGAT
ACAAGGAAACGGAACTGTCC

Downstream 100 bases:

>100_bases
TCGGCATGAAATAAAAAGGGCGGAAGCATAACATGCTTCCGCCCTTTTTTGCGCCCCGTCAGTTCTGACGGGTCAGGTTC
GACAGGCTTTTACTTTCTTG

Product: heat shock protein HtpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MKRIFLFVVTNLAILLVLSITLRLLGVDRMLDEQGVGINYNSLLVMAAVIGFGGSLISLAMSKWSAKRMTGAVVIEQPSD
PTERWLVETVRRQAERVGIGMPEVAIYEAPDMNAFATGMNRNEALVAVSTGLLQAMTKDEIEGVLAHEISHVANGDMVTL
ALIQGVVNTFVIFLSRVIGHFVDRVIFKTEREYGPAFMVTTLIAQMVLGILASIIVMWFSRQREFRADAGGAQLAGRNKM
IAALERLQRRHEPSQLPERLEAFGISGGEGGLRTLFMSHPPLEVRIAALRAMT

Sequences:

>Translated_293_residues
MKRIFLFVVTNLAILLVLSITLRLLGVDRMLDEQGVGINYNSLLVMAAVIGFGGSLISLAMSKWSAKRMTGAVVIEQPSD
PTERWLVETVRRQAERVGIGMPEVAIYEAPDMNAFATGMNRNEALVAVSTGLLQAMTKDEIEGVLAHEISHVANGDMVTL
ALIQGVVNTFVIFLSRVIGHFVDRVIFKTEREYGPAFMVTTLIAQMVLGILASIIVMWFSRQREFRADAGGAQLAGRNKM
IAALERLQRRHEPSQLPERLEAFGISGGEGGLRTLFMSHPPLEVRIAALRAMT
>Mature_293_residues
MKRIFLFVVTNLAILLVLSITLRLLGVDRMLDEQGVGINYNSLLVMAAVIGFGGSLISLAMSKWSAKRMTGAVVIEQPSD
PTERWLVETVRRQAERVGIGMPEVAIYEAPDMNAFATGMNRNEALVAVSTGLLQAMTKDEIEGVLAHEISHVANGDMVTL
ALIQGVVNTFVIFLSRVIGHFVDRVIFKTEREYGPAFMVTTLIAQMVLGILASIIVMWFSRQREFRADAGGAQLAGRNKM
IAALERLQRRHEPSQLPERLEAFGISGGEGGLRTLFMSHPPLEVRIAALRAMT

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=297, Percent_Identity=53.5353535353535, Blast_Score=295, Evalue=2e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 32192; Mature: 32192

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRIFLFVVTNLAILLVLSITLRLLGVDRMLDEQGVGINYNSLLVMAAVIGFGGSLISLA
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHH
MSKWSAKRMTGAVVIEQPSDPTERWLVETVRRQAERVGIGMPEVAIYEAPDMNAFATGMN
HHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHCCCC
RNEALVAVSTGLLQAMTKDEIEGVLAHEISHVANGDMVTLALIQGVVNTFVIFLSRVIGH
CCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FVDRVIFKTEREYGPAFMVTTLIAQMVLGILASIIVMWFSRQREFRADAGGAQLAGRNKM
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCHHH
IAALERLQRRHEPSQLPERLEAFGISGGEGGLRTLFMSHPPLEVRIAALRAMT
HHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHEECCCCHHHHHHHHHHCC
>Mature Secondary Structure
MKRIFLFVVTNLAILLVLSITLRLLGVDRMLDEQGVGINYNSLLVMAAVIGFGGSLISLA
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHH
MSKWSAKRMTGAVVIEQPSDPTERWLVETVRRQAERVGIGMPEVAIYEAPDMNAFATGMN
HHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHCCCC
RNEALVAVSTGLLQAMTKDEIEGVLAHEISHVANGDMVTLALIQGVVNTFVIFLSRVIGH
CCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FVDRVIFKTEREYGPAFMVTTLIAQMVLGILASIIVMWFSRQREFRADAGGAQLAGRNKM
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCHHH
IAALERLQRRHEPSQLPERLEAFGISGGEGGLRTLFMSHPPLEVRIAALRAMT
HHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHEECCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]