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The map label for this gene is nuoE [H]

Identifier: 82702145

GI number: 82702145

Start: 1176160

End: 1176666

Strand: Direct

Name: nuoE [H]

Synonym: Nmul_A1016

Alternate gene names: 82702145

Gene position: 1176160-1176666 (Clockwise)

Preceding gene: 82702144

Following gene: 82702146

Centisome position: 36.94

GC content: 56.8

Gene sequence:

>507_bases
ATGCTGAGCGAGCAGGAGAGGAAAGAAATAGAAGCACATGCGCGGCACTACCCGAATAATCGGGCGGTATGCATCGAGGC
ACTCAAGATCGTGCAGCAGCATCGCGGCTGGGTATCGAATGAGGGGATTGCCGACGTGGCCGAGGCGTTGCAGATGAAGC
CGGCCGAACTGGAGAGCGTTGCAACCTTCTACAACATGATTTTCCGCAAGCCGGTAGGCAAGCACGTCATTTTGCTATGC
GACAGCGTCAGTTGCTGGATCATGGGTTATGAACGCTTGCGCCAGCACCTGGGAGACAGGTTGGGTATCAGGCCGGGCCA
GACCACCGCCGACGGGCGCTTCACGCTGTTGCCGAACGTGTGCCTGGGCGCCTGCGATCATGCTCCTGTCATGATGGTGG
ATGACGCGCATTACCAGGACCTGGATCCCGCCAGGATCGATCAGATTCTGGCAAGTTATCAACAGGAAGAAGAAAAATCG
ACCGATGGAAACACCGCTGACGCATAA

Upstream 100 bases:

>100_bases
TGATGATTTCGGATTTGATCGCCATTCTGGGCAGCATCGATTTTGTCATGGCGGACGTGGATCGCTGATGGATGGCTGAG
GGGGATATTGAGAGGAAACA

Downstream 100 bases:

>100_bases
CATTTCACCGGGCAGGGAACCTCCGGATCTTGCGCAGTACGAGAAGGCCGGAGGTTATGGCGCGCTGCGCAAGGCGCTCG
GTATGGCGCCGGCGGAAATT

Product: NADH-quinone oxidoreductase subunit E

Products: NA

Alternate protein names: NADH dehydrogenase I subunit E; NDH-1 subunit E [H]

Number of amino acids: Translated: 168; Mature: 168

Protein sequence:

>168_residues
MLSEQERKEIEAHARHYPNNRAVCIEALKIVQQHRGWVSNEGIADVAEALQMKPAELESVATFYNMIFRKPVGKHVILLC
DSVSCWIMGYERLRQHLGDRLGIRPGQTTADGRFTLLPNVCLGACDHAPVMMVDDAHYQDLDPARIDQILASYQQEEEKS
TDGNTADA

Sequences:

>Translated_168_residues
MLSEQERKEIEAHARHYPNNRAVCIEALKIVQQHRGWVSNEGIADVAEALQMKPAELESVATFYNMIFRKPVGKHVILLC
DSVSCWIMGYERLRQHLGDRLGIRPGQTTADGRFTLLPNVCLGACDHAPVMMVDDAHYQDLDPARIDQILASYQQEEEKS
TDGNTADA
>Mature_168_residues
MLSEQERKEIEAHARHYPNNRAVCIEALKIVQQHRGWVSNEGIADVAEALQMKPAELESVATFYNMIFRKPVGKHVILLC
DSVSCWIMGYERLRQHLGDRLGIRPGQTTADGRFTLLPNVCLGACDHAPVMMVDDAHYQDLDPARIDQILASYQQEEEKS
TDGNTADA

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG1905

COG function: function code C; NADH:ubiquinone oxidoreductase 24 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 24 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI222080062, Length=151, Percent_Identity=36.4238410596026, Blast_Score=112, Evalue=1e-25,
Organism=Escherichia coli, GI1788621, Length=153, Percent_Identity=50.9803921568627, Blast_Score=162, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17561328, Length=151, Percent_Identity=33.7748344370861, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI18859877, Length=151, Percent_Identity=35.7615894039735, Blast_Score=107, Evalue=4e-24,
Organism=Drosophila melanogaster, GI21355353, Length=158, Percent_Identity=34.1772151898734, Blast_Score=107, Evalue=5e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002023
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01257 Complex1_24kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 18905; Mature: 18905

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS01099 COMPLEX1_24K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSEQERKEIEAHARHYPNNRAVCIEALKIVQQHRGWVSNEGIADVAEALQMKPAELESV
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHH
ATFYNMIFRKPVGKHVILLCDSVSCWIMGYERLRQHLGDRLGIRPGQTTADGRFTLLPNV
HHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCHH
CLGACDHAPVMMVDDAHYQDLDPARIDQILASYQQEEEKSTDGNTADA
HHCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MLSEQERKEIEAHARHYPNNRAVCIEALKIVQQHRGWVSNEGIADVAEALQMKPAELESV
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHH
ATFYNMIFRKPVGKHVILLCDSVSCWIMGYERLRQHLGDRLGIRPGQTTADGRFTLLPNV
HHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCHH
CLGACDHAPVMMVDDAHYQDLDPARIDQILASYQQEEEKSTDGNTADA
HHCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12089438 [H]