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The map label for this gene is nuoC

Identifier: 82702144

GI number: 82702144

Start: 1174301

End: 1176127

Strand: Direct

Name: nuoC

Synonym: Nmul_A1015

Alternate gene names: 82702144

Gene position: 1174301-1176127 (Clockwise)

Preceding gene: 82702143

Following gene: 82702145

Centisome position: 36.88

GC content: 56.87

Gene sequence:

>1827_bases
GTGAGCGCAGCCTCCAGCCTTGCCCCACAGCGGTATATGCAGGACATGGGCGGTGCATCGAACGCTTCAGATGTACTGGA
AGAACTGAAGAACCGCTTTGGCCCCCCTGGCACTGATAACCCAGGAGGGCCAATGGGTGTAGTGCAAAAAACCGGCGATG
ACCTTCCCACGCAATGGGTCTCCAGGAACAGGGTACATGAGGTTCTGCACTACCTGAAACTGAAAGCGGAGCGGCCTTAC
CGCATGCTGTACGACCTGACCGCGATTGACGAACGCACACGCGTACACCGGGAAGACCAGCCGGCAAGCCGGTTCACTGT
CATCTATCACCTGCTGTCGTTCGAGCGTAATGCGGACGTGTGCCTCAAGGTCGCGCTCACCGATACTGATCTTCGGATGC
CCACCATTACCGATATCTGGCCTGCGGCAAACTGGTACGAGCGTGAGATATGGGACATGTTCGGGATCGTCTTCGACGGA
CACCCGCACCTGCGTCGAATTTTGTTACCTCCCTGGTGGCAGGGTCACGCCCTGCGCAAGGATCATCCGGCTCGCGCGAC
GGAGATGGAACCATTCCATTTGTCCACGGAGAAGGAGGAGGCTGAGCAGGAGACACTGCGTTTTCATCCTGAAGAATGGG
GAATGCGGCGCACACATGACGGCACCGATTTCATGTTCCTCAACCTGGGGCCGAACCATCCAAGCGTGCATGGCGTATTT
CGCATTGTGCTGCAGCTCGACGGCGAGGAAATCATCGATGCTGTGCCAGAGATCGGCTTTCACCACCGGGGAGCAGAAAA
GATGGGTGAGCGCCAATCATGGCATACCTATATTCCCTACACCGACCGCATCGATTACCTGGGAGGGGTCATGAACAACC
TTCCCTATGTGCTGGCCGTGGAGAAACTGGCAGGCATTGAAGTGCCCGATCGGGTAAAGGTGATGCGCGTGATGATGGCA
GAATTTTTTCGCATTGCAAGCCATCTGGTGTTCTATGGGACTTTTACCCAGGATCTGGGCGCGCTTTCCCCGGTATTTTT
CATGTTCACCGACCGCGAACGGGTATTCGATGTCGTGGAAGCCATCTGCGGGGGGCGAATGCATCCGAGCTGGTATCGCA
TCGGCGGTGTGGCCCAGGACTTGCCTAATGGATGGGATAGGATGGTGCGGGATTTCCTGGATTATATGCCTGCAAGGCTG
GATGAGTATGACAAGATTGCTGTGGGCAACCGCATCCTGAAAGCCCGGACGCGTGGCGTCGGCGGTTATTCGATAGATGA
GGCGATCGAATGGGGCGTGACCGGCCCCAATCTGCGCGCCTGCGGCTTCGAATGGGATTTCCGCAAGGCGCGGCCCTATT
CGGGCTACGATCAGTTCGAGTTCGATGTGCCCACCGGCCAGCATGGCGATTGCTATGACCGCTGTGCCGTTCGTGTCCAG
GAAATCCGCCAGAGCCTGCGCATCATCGATCAGTGCCTGGAAAACATGCCCGCCGGGGCGCATAAAGCGGATCATCCGCT
CACCACGCCGCCCCTCAAGAAGCATACCTTGCATGACATCGAAACGCTCATCGATCATTTCCTGGGTGTGAGCTGGGGAC
CTGTCATTCCTCCGGGGGAAGCATTCGTAGGCATCGAGGCGACCAAGGGAAACAACGGCTATTACCTGATTAGCGACGGC
AATACCACGGCTTATCGGGTGCGTATCCGAACACCTTCCTTTCCGCACCTGCAAATGATTCCTTTGATCAGCCGTGGACT
GATGATTTCGGATTTGATCGCCATTCTGGGCAGCATCGATTTTGTCATGGCGGACGTGGATCGCTGA

Upstream 100 bases:

>100_bases
CGCAGGGGATCGAGCGACCGGCTGAGGAATCGCAGCGGGATCTCAAGCGTTCCGGCCGAATGTGCGCCACCACCCTGCGC
AGTCCCGACGAGGTACAAAA

Downstream 100 bases:

>100_bases
TGGATGGCTGAGGGGGATATTGAGAGGAAACAATGCTGAGCGAGCAGGAGAGGAAAGAAATAGAAGCACATGCGCGGCAC
TACCCGAATAATCGGGCGGT

Product: bifunctional NADH:ubiquinone oxidoreductase subunit C/D

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C/D; NDH-1 subunit C/D

Number of amino acids: Translated: 608; Mature: 607

Protein sequence:

>608_residues
MSAASSLAPQRYMQDMGGASNASDVLEELKNRFGPPGTDNPGGPMGVVQKTGDDLPTQWVSRNRVHEVLHYLKLKAERPY
RMLYDLTAIDERTRVHREDQPASRFTVIYHLLSFERNADVCLKVALTDTDLRMPTITDIWPAANWYEREIWDMFGIVFDG
HPHLRRILLPPWWQGHALRKDHPARATEMEPFHLSTEKEEAEQETLRFHPEEWGMRRTHDGTDFMFLNLGPNHPSVHGVF
RIVLQLDGEEIIDAVPEIGFHHRGAEKMGERQSWHTYIPYTDRIDYLGGVMNNLPYVLAVEKLAGIEVPDRVKVMRVMMA
EFFRIASHLVFYGTFTQDLGALSPVFFMFTDRERVFDVVEAICGGRMHPSWYRIGGVAQDLPNGWDRMVRDFLDYMPARL
DEYDKIAVGNRILKARTRGVGGYSIDEAIEWGVTGPNLRACGFEWDFRKARPYSGYDQFEFDVPTGQHGDCYDRCAVRVQ
EIRQSLRIIDQCLENMPAGAHKADHPLTTPPLKKHTLHDIETLIDHFLGVSWGPVIPPGEAFVGIEATKGNNGYYLISDG
NTTAYRVRIRTPSFPHLQMIPLISRGLMISDLIAILGSIDFVMADVDR

Sequences:

>Translated_608_residues
MSAASSLAPQRYMQDMGGASNASDVLEELKNRFGPPGTDNPGGPMGVVQKTGDDLPTQWVSRNRVHEVLHYLKLKAERPY
RMLYDLTAIDERTRVHREDQPASRFTVIYHLLSFERNADVCLKVALTDTDLRMPTITDIWPAANWYEREIWDMFGIVFDG
HPHLRRILLPPWWQGHALRKDHPARATEMEPFHLSTEKEEAEQETLRFHPEEWGMRRTHDGTDFMFLNLGPNHPSVHGVF
RIVLQLDGEEIIDAVPEIGFHHRGAEKMGERQSWHTYIPYTDRIDYLGGVMNNLPYVLAVEKLAGIEVPDRVKVMRVMMA
EFFRIASHLVFYGTFTQDLGALSPVFFMFTDRERVFDVVEAICGGRMHPSWYRIGGVAQDLPNGWDRMVRDFLDYMPARL
DEYDKIAVGNRILKARTRGVGGYSIDEAIEWGVTGPNLRACGFEWDFRKARPYSGYDQFEFDVPTGQHGDCYDRCAVRVQ
EIRQSLRIIDQCLENMPAGAHKADHPLTTPPLKKHTLHDIETLIDHFLGVSWGPVIPPGEAFVGIEATKGNNGYYLISDG
NTTAYRVRIRTPSFPHLQMIPLISRGLMISDLIAILGSIDFVMADVDR
>Mature_607_residues
SAASSLAPQRYMQDMGGASNASDVLEELKNRFGPPGTDNPGGPMGVVQKTGDDLPTQWVSRNRVHEVLHYLKLKAERPYR
MLYDLTAIDERTRVHREDQPASRFTVIYHLLSFERNADVCLKVALTDTDLRMPTITDIWPAANWYEREIWDMFGIVFDGH
PHLRRILLPPWWQGHALRKDHPARATEMEPFHLSTEKEEAEQETLRFHPEEWGMRRTHDGTDFMFLNLGPNHPSVHGVFR
IVLQLDGEEIIDAVPEIGFHHRGAEKMGERQSWHTYIPYTDRIDYLGGVMNNLPYVLAVEKLAGIEVPDRVKVMRVMMAE
FFRIASHLVFYGTFTQDLGALSPVFFMFTDRERVFDVVEAICGGRMHPSWYRIGGVAQDLPNGWDRMVRDFLDYMPARLD
EYDKIAVGNRILKARTRGVGGYSIDEAIEWGVTGPNLRACGFEWDFRKARPYSGYDQFEFDVPTGQHGDCYDRCAVRVQE
IRQSLRIIDQCLENMPAGAHKADHPLTTPPLKKHTLHDIETLIDHFLGVSWGPVIPPGEAFVGIEATKGNNGYYLISDGN
TTAYRVRIRTPSFPHLQMIPLISRGLMISDLIAILGSIDFVMADVDR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0649

COG function: function code C; NADH:ubiquinone oxidoreductase 49 kD subunit 7

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the complex I 49 kDa subunit family

Homologues:

Organism=Homo sapiens, GI4758786, Length=382, Percent_Identity=43.979057591623, Blast_Score=334, Evalue=2e-91,
Organism=Homo sapiens, GI260898743, Length=372, Percent_Identity=43.8172043010753, Blast_Score=325, Evalue=1e-88,
Organism=Homo sapiens, GI4758788, Length=116, Percent_Identity=42.2413793103448, Blast_Score=91, Evalue=3e-18,
Organism=Escherichia coli, GI145693162, Length=585, Percent_Identity=62.9059829059829, Blast_Score=783, Evalue=0.0,
Organism=Escherichia coli, GI1789076, Length=512, Percent_Identity=27.1484375, Blast_Score=173, Evalue=3e-44,
Organism=Escherichia coli, GI1788832, Length=601, Percent_Identity=27.4542429284526, Blast_Score=157, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI17555284, Length=393, Percent_Identity=43.2569974554707, Blast_Score=349, Evalue=2e-96,
Organism=Caenorhabditis elegans, GI17568379, Length=384, Percent_Identity=44.2708333333333, Blast_Score=348, Evalue=3e-96,
Organism=Caenorhabditis elegans, GI71990788, Length=116, Percent_Identity=37.0689655172414, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI32563621, Length=116, Percent_Identity=37.0689655172414, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24638644, Length=384, Percent_Identity=44.2708333333333, Blast_Score=355, Evalue=5e-98,
Organism=Drosophila melanogaster, GI221459469, Length=418, Percent_Identity=39.7129186602871, Blast_Score=349, Evalue=3e-96,
Organism=Drosophila melanogaster, GI24656494, Length=136, Percent_Identity=36.7647058823529, Blast_Score=84, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOCD_NITMU (Q2YAA3)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_411710.1
- HSSP:   Q56220
- ProteinModelPortal:   Q2YAA3
- STRING:   Q2YAA3
- GeneID:   3786540
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A1015
- eggNOG:   COG0649
- HOGENOM:   HBG459705
- OMA:   PHLQQIP
- PhylomeDB:   Q2YAA3
- ProtClustDB:   PRK11742
- BioCyc:   NMUL323848:NMUL_A1015-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01359
- InterPro:   IPR010219
- InterPro:   IPR010218
- InterPro:   IPR023062
- InterPro:   IPR001135
- InterPro:   IPR001268
- InterPro:   IPR014029
- InterPro:   IPR020396
- InterPro:   IPR022885
- ProDom:   PD001581
- TIGRFAMs:   TIGR01961
- TIGRFAMs:   TIGR01962

Pfam domain/function: PF00329 Complex1_30kDa; PF00346 Complex1_49kDa

EC number: =1.6.99.5

Molecular weight: Translated: 69449; Mature: 69318

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS00542 COMPLEX1_30K; PS00535 COMPLEX1_49K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAASSLAPQRYMQDMGGASNASDVLEELKNRFGPPGTDNPGGPMGVVQKTGDDLPTQWV
CCCHHHCCHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCCCCCCHHHH
SRNRVHEVLHYLKLKAERPYRMLYDLTAIDERTRVHREDQPASRFTVIYHLLSFERNADV
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCE
CLKVALTDTDLRMPTITDIWPAANWYEREIWDMFGIVFDGHPHLRRILLPPWWQGHALRK
EEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHEECCCHHHHHEECCCCCCCCCCCC
DHPARATEMEPFHLSTEKEEAEQETLRFHPEEWGMRRTHDGTDFMFLNLGPNHPSVHGVF
CCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHCCCCCCCCCCEEEEEECCCCCHHHHHH
RIVLQLDGEEIIDAVPEIGFHHRGAEKMGERQSWHTYIPYTDRIDYLGGVMNNLPYVLAV
HHHHHCCCHHHHHHHHHCCCCCCCHHHHCCCCCCEEECCCCCHHHHHHHHHHCCCCEEEH
EKLAGIEVPDRVKVMRVMMAEFFRIASHLVFYGTFTQDLGALSPVFFMFTDRERVFDVVE
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHCCEEEEECCHHHHHHHHH
AICGGRMHPSWYRIGGVAQDLPNGWDRMVRDFLDYMPARLDEYDKIAVGNRILKARTRGV
HHHCCCCCCCHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCC
GGYSIDEAIEWGVTGPNLRACGFEWDFRKARPYSGYDQFEFDVPTGQHGDCYDRCAVRVQ
CCCCHHHHHHCCCCCCCCEECCCCCCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHH
EIRQSLRIIDQCLENMPAGAHKADHPLTTPPLKKHTLHDIETLIDHFLGVSWGPVIPPGE
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
AFVGIEATKGNNGYYLISDGNTTAYRVRIRTPSFPHLQMIPLISRGLMISDLIAILGSID
EEEEEEEEECCCCEEEEECCCCEEEEEEEECCCCCCEEEHHHHHCCHHHHHHHHHHCCHH
FVMADVDR
HHEECCCC
>Mature Secondary Structure 
SAASSLAPQRYMQDMGGASNASDVLEELKNRFGPPGTDNPGGPMGVVQKTGDDLPTQWV
CCHHHCCHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCCCCCCHHHH
SRNRVHEVLHYLKLKAERPYRMLYDLTAIDERTRVHREDQPASRFTVIYHLLSFERNADV
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCE
CLKVALTDTDLRMPTITDIWPAANWYEREIWDMFGIVFDGHPHLRRILLPPWWQGHALRK
EEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHEECCCHHHHHEECCCCCCCCCCCC
DHPARATEMEPFHLSTEKEEAEQETLRFHPEEWGMRRTHDGTDFMFLNLGPNHPSVHGVF
CCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHCCCCCCCCCCEEEEEECCCCCHHHHHH
RIVLQLDGEEIIDAVPEIGFHHRGAEKMGERQSWHTYIPYTDRIDYLGGVMNNLPYVLAV
HHHHHCCCHHHHHHHHHCCCCCCCHHHHCCCCCCEEECCCCCHHHHHHHHHHCCCCEEEH
EKLAGIEVPDRVKVMRVMMAEFFRIASHLVFYGTFTQDLGALSPVFFMFTDRERVFDVVE
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHCCEEEEECCHHHHHHHHH
AICGGRMHPSWYRIGGVAQDLPNGWDRMVRDFLDYMPARLDEYDKIAVGNRILKARTRGV
HHHCCCCCCCHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCC
GGYSIDEAIEWGVTGPNLRACGFEWDFRKARPYSGYDQFEFDVPTGQHGDCYDRCAVRVQ
CCCCHHHHHHCCCCCCCCEECCCCCCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHH
EIRQSLRIIDQCLENMPAGAHKADHPLTTPPLKKHTLHDIETLIDHFLGVSWGPVIPPGE
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
AFVGIEATKGNNGYYLISDGNTTAYRVRIRTPSFPHLQMIPLISRGLMISDLIAILGSID
EEEEEEEEECCCCEEEEECCCCEEEEEEEECCCCCCEEEHHHHHCCHHHHHHHHHHCCHH
FVMADVDR
HHEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA