Click here to switch to the map view.

The map label for this gene is nuoA

Identifier: 82702142

GI number: 82702142

Start: 1173215

End: 1173658

Strand: Direct

Name: nuoA

Synonym: Nmul_A1013

Alternate gene names: 82702142

Gene position: 1173215-1173658 (Clockwise)

Preceding gene: 82702140

Following gene: 82702143

Centisome position: 36.84

GC content: 54.5

Gene sequence:

>444_bases
TTGAATGCTTCCGCGACACAAGCAACAGAAATCTGGCCCCTGGTTGCATACTTTTTCCTCGTCGTCATGCTGGTGGTGGG
CGTCATGGCGCTTTCGTACATCATTGGCGAGCGTCATCGCTCCAAGGCTACGGATGAGCCGTTTGAAAGCGGCATTGTCA
CCGTCGGCCTTGCGCGCTTCCGCCTCTCTGCCAAATTCTATCTGATCGCAGTGTTCTTTGTGATCTTCGATGTAGAAGCC
GTATTCCTTTTTGCCTGGGCCGTTGCTTTTCGTGAATTGGGCTGGCCGGGTTATATCGAGGCCATCATCTTCATATCTAT
TCTCGGAGCGGCCCTCGCTTATTTGTGGCGACTGGGGGCGCTGGACTGGGGGCCGCCCAGGCATTCGGCTGGCAGGTTTG
CCAAAGACTCAAGGAGTCCAAATCATGCGGTGGTCTCTAAGTAA

Upstream 100 bases:

>100_bases
TCTCAGGAAGTCACCCCTCTCAGGACCCGCAGGTTTTTGGGTGGACCAGCCTGTTTAATCCTGGTGTCATCAAAGGACCA
AGCACAAAGGAGCCTAATCC

Downstream 100 bases:

>100_bases
GCCATCTGACAAACCATCCGGGCCAGCAACGCCCGGGTCTTCAATAATTCGCGATAACGGTTTTGAGGAAGACGGGCGCC
GCAGCGTGTTGCTGACGCGA

Product: NADH-ubiquinone/plastoquinone oxidoreductase, chain 3

Products: NA

Alternate protein names: NADH dehydrogenase I subunit A; NDH-1 subunit A; NUO1

Number of amino acids: Translated: 147; Mature: 147

Protein sequence:

>147_residues
MNASATQATEIWPLVAYFFLVVMLVVGVMALSYIIGERHRSKATDEPFESGIVTVGLARFRLSAKFYLIAVFFVIFDVEA
VFLFAWAVAFRELGWPGYIEAIIFISILGAALAYLWRLGALDWGPPRHSAGRFAKDSRSPNHAVVSK

Sequences:

>Translated_147_residues
MNASATQATEIWPLVAYFFLVVMLVVGVMALSYIIGERHRSKATDEPFESGIVTVGLARFRLSAKFYLIAVFFVIFDVEA
VFLFAWAVAFRELGWPGYIEAIIFISILGAALAYLWRLGALDWGPPRHSAGRFAKDSRSPNHAVVSK
>Mature_147_residues
MNASATQATEIWPLVAYFFLVVMLVVGVMALSYIIGERHRSKATDEPFESGIVTVGLARFRLSAKFYLIAVFFVIFDVEA
VFLFAWAVAFRELGWPGYIEAIIFISILGAALAYLWRLGALDWGPPRHSAGRFAKDSRSPNHAVVSK

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0838

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 3 (chain A)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 3 family

Homologues:

Organism=Escherichia coli, GI1788625, Length=140, Percent_Identity=46.4285714285714, Blast_Score=127, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOA_NITMU (Q2YAA5)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_411708.1
- STRING:   Q2YAA5
- GeneID:   3786538
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A1013
- eggNOG:   COG0838
- HOGENOM:   HBG605540
- OMA:   AWAVAFR
- PhylomeDB:   Q2YAA5
- ProtClustDB:   CLSK747150
- BioCyc:   NMUL323848:NMUL_A1013-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01394
- InterPro:   IPR023043
- InterPro:   IPR000440
- PANTHER:   PTHR11058

Pfam domain/function: PF00507 Oxidored_q4

EC number: =1.6.99.5

Molecular weight: Translated: 16359; Mature: 16359

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x103e0a90)-; HASH(0x12a7f3d8)-; HASH(0x12da3220)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNASATQATEIWPLVAYFFLVVMLVVGVMALSYIIGERHRSKATDEPFESGIVTVGLARF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCHHHHHHHHH
RLSAKFYLIAVFFVIFDVEAVFLFAWAVAFRELGWPGYIEAIIFISILGAALAYLWRLGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC
LDWGPPRHSAGRFAKDSRSPNHAVVSK
CCCCCCCCCCCCCHHCCCCCCCCCCCH
>Mature Secondary Structure
MNASATQATEIWPLVAYFFLVVMLVVGVMALSYIIGERHRSKATDEPFESGIVTVGLARF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCHHHHHHHHH
RLSAKFYLIAVFFVIFDVEAVFLFAWAVAFRELGWPGYIEAIIFISILGAALAYLWRLGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC
LDWGPPRHSAGRFAKDSRSPNHAVVSK
CCCCCCCCCCCCCHHCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA