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The map label for this gene is accC [H]

Identifier: 82702072

GI number: 82702072

Start: 1090857

End: 1094495

Strand: Direct

Name: accC [H]

Synonym: Nmul_A0943

Alternate gene names: 82702072

Gene position: 1090857-1094495 (Clockwise)

Preceding gene: 82702071

Following gene: 82702073

Centisome position: 34.26

GC content: 56.99

Gene sequence:

>3639_bases
ATGTTTGAAAAAGTATTGATAGCCAATCGCGGCGCCATTGCTTGTCGGATTATCCGCACTCTACGGCGTATGGGGGTAAA
GAGCGTTGCCATCTATACCGAAGCAGATGCGTTATCCCGGCATGTGATCGAAGCCGATGAAGCCTACTGCATAGGCAGTG
GAGTCGCCGCGGAAAGCTATCTGCGCGCCGAAAAGATCCTGGAGGTTGCGAGCCATGCGGGGGCAAATGCAATTCATCCA
GGATATGGCTTCCTCAGTGAGAAAGCTGAATTTGCCGAGCAATGCGCTGACCATGGTATTTCCTTCATTGGCCCCACTCC
CCATCAGATGCGCGCGTTCGGCTTGAAGCACACGGCGCGCAAACTGGCGCTGCAGAACCGGGTACCGCTGCTGCCGGGCA
CAGGCTTGCTCGAAGACCTGGATGAGGCCTTGCGCCAGGCAGCTCATATCGGTTACCCGGTCATGCTGAAAAGCACGGCG
GGAGGGGGCGGCATAGGCATACGTTTGTGCTGGAACAAGGAAGAGTTGAGTGCAAACTACGAATTGGTGAAATACCTCGC
GCAGAACAATTTCAAGGACGCCGGCCTGTTTCTCGAAAAATATGTGGAGAAGGCGCGCCATATCGAGGTGCAGATATTCG
GTGACGGCAAGGGTGGGGTGATCGCACTGGGGGAGCGCGACTGCTCGATGCAGCGGCGTAACCAAAAGGTGATCGAAGAA
ACCCCGGCCCCCGATCTGCCGCCACGCGTGCGCCAGGCGTTGCTGAATGCCGCGGTACGTTTGGGCAAGTCAGTCAATTA
CCAGTCTGCGGGTACGGTGGAGTATATTTTCGATGCCTCCGCTGCAGAATTTTATTTCCTGGAAGTGAATACGCGGCTGC
AGGTCGAGCACGGGGTAACTGAGGAAGTGACCGGTATCGACTTGGTGGAATGGATGGTTCGGCAAGCCGCCGGAGACTTG
CCCCCTCTCGATTCATTCGATATCCAGCCGCAGGGGGCCTCCCTCCAGGTACGCGTGTACGCCGAGAACGCGGTCAAAGA
TTTTCAACCTTCCTGCGGTATTCTCACCGCCGCAGAGTTTCCGCCTCCGTCCGCGGCACGCGTGGAAACCTGGGTGGAAC
GCGGCGTCGAGGTCTCGCCATTTTATGATCCTATGCTGGCAAAAATCATCGTGCATGCGCCGGACCGGGAGCAGGCCATT
GCGCGGCTGCTGCAAGCCCTGGACGTGACGGCATTGCACGGAGTGGAAACCAACGTCGGTTATCTCAGGCAGACTCTACG
CAGCGATGCGTTTCGAAGCGCCCAACACACGACCAGCTTTCTGAACACTTTTCGTTATGCCGCCCATACGATCGATGTTC
TCAGTCCGGGTGTACAGACTACGGTGCAGGATTATCCCGGGCGGACAGGATACTGGAGTATCGGCGTGCCGCCATCGGGA
CCGATGGATGGTCTGGCGTTCCGCCTGGCCAATCGTCTCGTCGATAACAGCGAGGATAAGGCGGGGTTGGAGATTACGCT
TTCCGGTCCGACGCTGCACTTCAACTGTGACAGCGTTATTGCGGTGTGCGGTGCGCCGATGGAGGTGCGCCTGGATGGTG
AGCCGCTTGCCTATTGGCGAGCGCATCGCGTCAAGGCCGGTTCGTTGTTGCAGTTCGGCAAACTCGTAAATCATGGGTGC
CGCGCTTATCTGGCGGTGCAAGGAGGAATTCGGGTTCCCGATTATCTGGGCAGCAAATCCACATTCACCCTCGGGCACTT
CGGGGGGCATGCAGGCCGCACGCTCCTCACCGGCGACGTGCTGCATATCTTTGAAGCCAGAAAAGACGGTAATGGCGGAT
TTGAGCAGGAACTGCCGGATGAATTGGTACCGCCCTACACCGACAGCTGGAAAATAGGGGTGTTGTACGGGCCGCACGGG
GCGCCGGATTTTTTCACGGAGCAGGATATCGAAACCTTCTTCGCCACGGATTGGGAAGTGCATTACAACTCCAATCGCAC
CGGCGTGCGGCTGATCGGCCCCAAGCCCCATTGGGCGCGCAGTGACGGCGGCGAAGCAGGACTGCATCCCTCCAATATCC
ACGACAACGCCTATGCCGTAGGTACCGTGGATTTTACGGGAGATATGCCTGTGATACTTGGTCCCGATGGCCCCAGCCTT
GGCGGCTTCGTGTGCCCGGTTACCATCATCCAGGCTGAATTTTGGAAGATGGGACAGCTCAAGCCGGGTGATCGCGTGCG
CTTCCACAGGATGTCGATGGAGCAGGCGCTGGGGCTGGAGTTGCAGCAGGATGCAAGGATAAAAGACCTCCGGGTCCCGC
AAAACGTTTCATCCGAGGGGGAGCAGGACGCAACCGACGCATCCATGCCTGTGCTCCACTTCATCCCGCAAAGCGACGGC
CATGTACAGGTGGTATATCGCCAGGCAGGCGATAAAAATCTGCTGGTCGAGTATGGTCCCCTCGAGCTCGATCTCAATTT
GCGCTTCCGTGCGCACGCCCTGATGGATTGGGTGCAGAAAACGTGCAATGACGGAGAACTGAAAGGCATTCTGGATCTGA
CACCCGGCATCCGTTCGCTGCAAGTGCATTTCGATTCCCGCGTACTCCCACGCGATAAGCTGCTGGAAATGCTGGTCAGC
GCGGAAAAGAAATTACCCGATATCGATGATATGGAGGTCCCGGCACGCGTCGTCCATCTTCCACTGTCATGGGACGATGG
TGCCACCCGCCTGGCGATAGAAAAGTACATGCAGTCGGTGCGCAGCGATGCACCCTGGTGCCCCAGCAATATCGAGTTCA
TCCGCCGGATCAACGGCCTCGACAGCATCGAGGAAGTGCAGCACATCCTGTTTTCTGCGAATTATCTTGTCATGGGACTG
GGTGACGTCTATCTCGGTGCGCCGGTTGCCACGCCCGTGGATCCGCGTCATCGGCTGGTGACCACGAAGTATAATCCTGC
GCGTACCTGGACGCCCGAGAATGCGGTTGGCATAGGGGGGGCCTATTTGTGCATATACGGGATGGAAGGTCCCGGAGGTT
ACCAGTTTGTGGGCCGCACGGTGCAGATGTGGAACCGGTACCTCCAGACAGCCGACTTCAAGGAAGGAAAACCCTGGCTG
CTGCGTTTCTTTGACCAGATTCGTTTCTATCCGGTTAGCGAAAGCGAACTGCTCAAGTTGCGCAAGGATTTCATTACCGG
ACACTTCAAGCTGAAGATCGAGGAGACAACATTCAGTTTGAAACAGTACAACGCTTTCCTGAAAGAAAATGCGGGATCCA
TCAGCGCTTTCAAAGCAAAGCAGCAGGCTGCGTTTGAAGCCGAGCGTGAACGCTGGAAGGCCCAAGGCAAGGCTGAGTAC
GTGAGCGAGGTTACACTCGAGGAAGCAGATGCGCAGAGCGAACTGGATTTGCCCGCTGATTCCCAGATTGTCAGTGCGCA
TGTAACCGGCACGGTATGGAAACTGCTCGTCAAGGAAGGGCAGCGTGTCGAAACGGGAGATCCAGTGGTAGTGGTGGAGT
CCATGAAAATGGAATTCTCTGTGGAGACACCGGTCAGCGGTAGGGTACGACAGCTATTCTGCAAGGAGGGGAGCCATATA
TCCGCCGGGCAGATGTTGCTTATCGTTCAGGAGGAATGA

Upstream 100 bases:

>100_bases
CACCCCCATTCGATTGCTGGTCTGGGACGACCCCAGTGAGATGAGCTTTACATAGTCCAGTTTCTATCCCGGCCGTTTTT
CACTCAACCGAGAATAAATC

Downstream 100 bases:

>100_bases
ATATGAACAAGCTCGATCTCCTGGGCGATATCCCGTCCCTGCTGCAACGTTATGTCACTGGGGAACTGACTCCTACCGGG
ATGGTAGAGGCGGTGCATGC

Product: allophanate hydrolase subunit 2

Products: NA

Alternate protein names: Acetyl-CoA carboxylase subunit A; ACC [H]

Number of amino acids: Translated: 1212; Mature: 1212

Protein sequence:

>1212_residues
MFEKVLIANRGAIACRIIRTLRRMGVKSVAIYTEADALSRHVIEADEAYCIGSGVAAESYLRAEKILEVASHAGANAIHP
GYGFLSEKAEFAEQCADHGISFIGPTPHQMRAFGLKHTARKLALQNRVPLLPGTGLLEDLDEALRQAAHIGYPVMLKSTA
GGGGIGIRLCWNKEELSANYELVKYLAQNNFKDAGLFLEKYVEKARHIEVQIFGDGKGGVIALGERDCSMQRRNQKVIEE
TPAPDLPPRVRQALLNAAVRLGKSVNYQSAGTVEYIFDASAAEFYFLEVNTRLQVEHGVTEEVTGIDLVEWMVRQAAGDL
PPLDSFDIQPQGASLQVRVYAENAVKDFQPSCGILTAAEFPPPSAARVETWVERGVEVSPFYDPMLAKIIVHAPDREQAI
ARLLQALDVTALHGVETNVGYLRQTLRSDAFRSAQHTTSFLNTFRYAAHTIDVLSPGVQTTVQDYPGRTGYWSIGVPPSG
PMDGLAFRLANRLVDNSEDKAGLEITLSGPTLHFNCDSVIAVCGAPMEVRLDGEPLAYWRAHRVKAGSLLQFGKLVNHGC
RAYLAVQGGIRVPDYLGSKSTFTLGHFGGHAGRTLLTGDVLHIFEARKDGNGGFEQELPDELVPPYTDSWKIGVLYGPHG
APDFFTEQDIETFFATDWEVHYNSNRTGVRLIGPKPHWARSDGGEAGLHPSNIHDNAYAVGTVDFTGDMPVILGPDGPSL
GGFVCPVTIIQAEFWKMGQLKPGDRVRFHRMSMEQALGLELQQDARIKDLRVPQNVSSEGEQDATDASMPVLHFIPQSDG
HVQVVYRQAGDKNLLVEYGPLELDLNLRFRAHALMDWVQKTCNDGELKGILDLTPGIRSLQVHFDSRVLPRDKLLEMLVS
AEKKLPDIDDMEVPARVVHLPLSWDDGATRLAIEKYMQSVRSDAPWCPSNIEFIRRINGLDSIEEVQHILFSANYLVMGL
GDVYLGAPVATPVDPRHRLVTTKYNPARTWTPENAVGIGGAYLCIYGMEGPGGYQFVGRTVQMWNRYLQTADFKEGKPWL
LRFFDQIRFYPVSESELLKLRKDFITGHFKLKIEETTFSLKQYNAFLKENAGSISAFKAKQQAAFEAERERWKAQGKAEY
VSEVTLEEADAQSELDLPADSQIVSAHVTGTVWKLLVKEGQRVETGDPVVVVESMKMEFSVETPVSGRVRQLFCKEGSHI
SAGQMLLIVQEE

Sequences:

>Translated_1212_residues
MFEKVLIANRGAIACRIIRTLRRMGVKSVAIYTEADALSRHVIEADEAYCIGSGVAAESYLRAEKILEVASHAGANAIHP
GYGFLSEKAEFAEQCADHGISFIGPTPHQMRAFGLKHTARKLALQNRVPLLPGTGLLEDLDEALRQAAHIGYPVMLKSTA
GGGGIGIRLCWNKEELSANYELVKYLAQNNFKDAGLFLEKYVEKARHIEVQIFGDGKGGVIALGERDCSMQRRNQKVIEE
TPAPDLPPRVRQALLNAAVRLGKSVNYQSAGTVEYIFDASAAEFYFLEVNTRLQVEHGVTEEVTGIDLVEWMVRQAAGDL
PPLDSFDIQPQGASLQVRVYAENAVKDFQPSCGILTAAEFPPPSAARVETWVERGVEVSPFYDPMLAKIIVHAPDREQAI
ARLLQALDVTALHGVETNVGYLRQTLRSDAFRSAQHTTSFLNTFRYAAHTIDVLSPGVQTTVQDYPGRTGYWSIGVPPSG
PMDGLAFRLANRLVDNSEDKAGLEITLSGPTLHFNCDSVIAVCGAPMEVRLDGEPLAYWRAHRVKAGSLLQFGKLVNHGC
RAYLAVQGGIRVPDYLGSKSTFTLGHFGGHAGRTLLTGDVLHIFEARKDGNGGFEQELPDELVPPYTDSWKIGVLYGPHG
APDFFTEQDIETFFATDWEVHYNSNRTGVRLIGPKPHWARSDGGEAGLHPSNIHDNAYAVGTVDFTGDMPVILGPDGPSL
GGFVCPVTIIQAEFWKMGQLKPGDRVRFHRMSMEQALGLELQQDARIKDLRVPQNVSSEGEQDATDASMPVLHFIPQSDG
HVQVVYRQAGDKNLLVEYGPLELDLNLRFRAHALMDWVQKTCNDGELKGILDLTPGIRSLQVHFDSRVLPRDKLLEMLVS
AEKKLPDIDDMEVPARVVHLPLSWDDGATRLAIEKYMQSVRSDAPWCPSNIEFIRRINGLDSIEEVQHILFSANYLVMGL
GDVYLGAPVATPVDPRHRLVTTKYNPARTWTPENAVGIGGAYLCIYGMEGPGGYQFVGRTVQMWNRYLQTADFKEGKPWL
LRFFDQIRFYPVSESELLKLRKDFITGHFKLKIEETTFSLKQYNAFLKENAGSISAFKAKQQAAFEAERERWKAQGKAEY
VSEVTLEEADAQSELDLPADSQIVSAHVTGTVWKLLVKEGQRVETGDPVVVVESMKMEFSVETPVSGRVRQLFCKEGSHI
SAGQMLLIVQEE
>Mature_1212_residues
MFEKVLIANRGAIACRIIRTLRRMGVKSVAIYTEADALSRHVIEADEAYCIGSGVAAESYLRAEKILEVASHAGANAIHP
GYGFLSEKAEFAEQCADHGISFIGPTPHQMRAFGLKHTARKLALQNRVPLLPGTGLLEDLDEALRQAAHIGYPVMLKSTA
GGGGIGIRLCWNKEELSANYELVKYLAQNNFKDAGLFLEKYVEKARHIEVQIFGDGKGGVIALGERDCSMQRRNQKVIEE
TPAPDLPPRVRQALLNAAVRLGKSVNYQSAGTVEYIFDASAAEFYFLEVNTRLQVEHGVTEEVTGIDLVEWMVRQAAGDL
PPLDSFDIQPQGASLQVRVYAENAVKDFQPSCGILTAAEFPPPSAARVETWVERGVEVSPFYDPMLAKIIVHAPDREQAI
ARLLQALDVTALHGVETNVGYLRQTLRSDAFRSAQHTTSFLNTFRYAAHTIDVLSPGVQTTVQDYPGRTGYWSIGVPPSG
PMDGLAFRLANRLVDNSEDKAGLEITLSGPTLHFNCDSVIAVCGAPMEVRLDGEPLAYWRAHRVKAGSLLQFGKLVNHGC
RAYLAVQGGIRVPDYLGSKSTFTLGHFGGHAGRTLLTGDVLHIFEARKDGNGGFEQELPDELVPPYTDSWKIGVLYGPHG
APDFFTEQDIETFFATDWEVHYNSNRTGVRLIGPKPHWARSDGGEAGLHPSNIHDNAYAVGTVDFTGDMPVILGPDGPSL
GGFVCPVTIIQAEFWKMGQLKPGDRVRFHRMSMEQALGLELQQDARIKDLRVPQNVSSEGEQDATDASMPVLHFIPQSDG
HVQVVYRQAGDKNLLVEYGPLELDLNLRFRAHALMDWVQKTCNDGELKGILDLTPGIRSLQVHFDSRVLPRDKLLEMLVS
AEKKLPDIDDMEVPARVVHLPLSWDDGATRLAIEKYMQSVRSDAPWCPSNIEFIRRINGLDSIEEVQHILFSANYLVMGL
GDVYLGAPVATPVDPRHRLVTTKYNPARTWTPENAVGIGGAYLCIYGMEGPGGYQFVGRTVQMWNRYLQTADFKEGKPWL
LRFFDQIRFYPVSESELLKLRKDFITGHFKLKIEETTFSLKQYNAFLKENAGSISAFKAKQQAAFEAERERWKAQGKAEY
VSEVTLEEADAQSELDLPADSQIVSAHVTGTVWKLLVKEGQRVETGDPVVVVESMKMEFSVETPVSGRVRQLFCKEGSHI
SAGQMLLIVQEE

Specific function: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA [H]

COG id: COG0439

COG function: function code I; Biotin carboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 biotin carboxylation domain [H]

Homologues:

Organism=Homo sapiens, GI116805327, Length=440, Percent_Identity=46.8181818181818, Blast_Score=395, Evalue=1e-109,
Organism=Homo sapiens, GI65506442, Length=444, Percent_Identity=44.8198198198198, Blast_Score=372, Evalue=1e-103,
Organism=Homo sapiens, GI189095269, Length=444, Percent_Identity=44.8198198198198, Blast_Score=372, Evalue=1e-102,
Organism=Homo sapiens, GI295821183, Length=444, Percent_Identity=44.8198198198198, Blast_Score=372, Evalue=1e-102,
Organism=Homo sapiens, GI106049528, Length=447, Percent_Identity=41.3870246085011, Blast_Score=331, Evalue=3e-90,
Organism=Homo sapiens, GI106049295, Length=447, Percent_Identity=41.3870246085011, Blast_Score=331, Evalue=3e-90,
Organism=Homo sapiens, GI106049292, Length=447, Percent_Identity=41.3870246085011, Blast_Score=331, Evalue=3e-90,
Organism=Homo sapiens, GI38679960, Length=504, Percent_Identity=30.952380952381, Blast_Score=211, Evalue=2e-54,
Organism=Homo sapiens, GI38679974, Length=504, Percent_Identity=30.952380952381, Blast_Score=211, Evalue=3e-54,
Organism=Homo sapiens, GI38679977, Length=504, Percent_Identity=30.952380952381, Blast_Score=211, Evalue=3e-54,
Organism=Homo sapiens, GI38679967, Length=504, Percent_Identity=30.952380952381, Blast_Score=211, Evalue=3e-54,
Organism=Homo sapiens, GI38679971, Length=504, Percent_Identity=30.952380952381, Blast_Score=211, Evalue=3e-54,
Organism=Homo sapiens, GI134142062, Length=505, Percent_Identity=29.9009900990099, Blast_Score=207, Evalue=4e-53,
Organism=Escherichia coli, GI1789654, Length=443, Percent_Identity=39.7291196388262, Blast_Score=318, Evalue=1e-87,
Organism=Escherichia coli, GI1786930, Length=314, Percent_Identity=34.0764331210191, Blast_Score=120, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI17567343, Length=443, Percent_Identity=44.2437923250564, Blast_Score=375, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI71987519, Length=442, Percent_Identity=45.9276018099548, Blast_Score=374, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI17562816, Length=447, Percent_Identity=43.6241610738255, Blast_Score=335, Evalue=8e-92,
Organism=Caenorhabditis elegans, GI133931226, Length=487, Percent_Identity=31.4168377823409, Blast_Score=209, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI71997168, Length=443, Percent_Identity=31.3769751693002, Blast_Score=188, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI71997163, Length=443, Percent_Identity=31.3769751693002, Blast_Score=188, Evalue=2e-47,
Organism=Saccharomyces cerevisiae, GI6319685, Length=1216, Percent_Identity=46.1348684210526, Blast_Score=1157, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319695, Length=447, Percent_Identity=38.7024608501119, Blast_Score=291, Evalue=4e-79,
Organism=Saccharomyces cerevisiae, GI6321376, Length=447, Percent_Identity=38.4787472035794, Blast_Score=286, Evalue=1e-77,
Organism=Saccharomyces cerevisiae, GI6324343, Length=510, Percent_Identity=30.5882352941176, Blast_Score=205, Evalue=4e-53,
Organism=Saccharomyces cerevisiae, GI6323863, Length=455, Percent_Identity=31.4285714285714, Blast_Score=197, Evalue=7e-51,
Organism=Drosophila melanogaster, GI24651757, Length=443, Percent_Identity=44.4695259593679, Blast_Score=383, Evalue=1e-106,
Organism=Drosophila melanogaster, GI24651759, Length=404, Percent_Identity=43.8118811881188, Blast_Score=337, Evalue=4e-92,
Organism=Drosophila melanogaster, GI281363050, Length=444, Percent_Identity=41.8918918918919, Blast_Score=331, Evalue=2e-90,
Organism=Drosophila melanogaster, GI24652224, Length=444, Percent_Identity=41.8918918918919, Blast_Score=331, Evalue=2e-90,
Organism=Drosophila melanogaster, GI24652222, Length=444, Percent_Identity=41.8918918918919, Blast_Score=331, Evalue=2e-90,
Organism=Drosophila melanogaster, GI24652220, Length=444, Percent_Identity=41.8918918918919, Blast_Score=331, Evalue=2e-90,
Organism=Drosophila melanogaster, GI24652218, Length=444, Percent_Identity=41.8918918918919, Blast_Score=331, Evalue=2e-90,
Organism=Drosophila melanogaster, GI24652212, Length=444, Percent_Identity=41.8918918918919, Blast_Score=331, Evalue=2e-90,
Organism=Drosophila melanogaster, GI24652210, Length=444, Percent_Identity=41.8918918918919, Blast_Score=331, Evalue=2e-90,
Organism=Drosophila melanogaster, GI24652214, Length=444, Percent_Identity=41.8918918918919, Blast_Score=331, Evalue=2e-90,
Organism=Drosophila melanogaster, GI19921944, Length=444, Percent_Identity=41.8918918918919, Blast_Score=331, Evalue=2e-90,
Organism=Drosophila melanogaster, GI24652216, Length=444, Percent_Identity=41.8918918918919, Blast_Score=331, Evalue=2e-90,
Organism=Drosophila melanogaster, GI161076409, Length=505, Percent_Identity=29.9009900990099, Blast_Score=193, Evalue=6e-49,
Organism=Drosophila melanogaster, GI161076407, Length=505, Percent_Identity=29.9009900990099, Blast_Score=193, Evalue=7e-49,
Organism=Drosophila melanogaster, GI24586460, Length=505, Percent_Identity=29.9009900990099, Blast_Score=193, Evalue=7e-49,
Organism=Drosophila melanogaster, GI24586458, Length=505, Percent_Identity=29.9009900990099, Blast_Score=193, Evalue=8e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR011054 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2 [H]

EC number: =6.3.4.14; =6.4.1.2 [H]

Molecular weight: Translated: 134153; Mature: 134153

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS50975 ATP_GRASP ; PS00866 CPSASE_1 ; PS00867 CPSASE_2 ; PS50979 BC ; PS50968 BIOTINYL_LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEKVLIANRGAIACRIIRTLRRMGVKSVAIYTEADALSRHVIEADEAYCIGSGVAAESY
CCCCEEEECCCHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHCCCCCEEECCCCHHHHH
LRAEKILEVASHAGANAIHPGYGFLSEKAEFAEQCADHGISFIGPTPHQMRAFGLKHTAR
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHH
KLALQNRVPLLPGTGLLEDLDEALRQAAHIGYPVMLKSTAGGGGIGIRLCWNKEELSANY
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEECHHHHCCCH
ELVKYLAQNNFKDAGLFLEKYVEKARHIEVQIFGDGKGGVIALGERDCSMQRRNQKVIEE
HHHHHHHHCCCCHHHHHHHHHHHHHHEEEEEEEECCCCCEEEECCCCCHHHHHHHHHHHC
TPAPDLPPRVRQALLNAAVRLGKSVNYQSAGTVEYIFDASAAEFYFLEVNTRLQVEHGVT
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCEEEEEEECCEEEECCCCC
EEVTGIDLVEWMVRQAAGDLPPLDSFDIQPQGASLQVRVYAENAVKDFQPSCGILTAAEF
HHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEECCCHHHCCCCCCEEEECCC
PPPSAARVETWVERGVEVSPFYDPMLAKIIVHAPDREQAIARLLQALDVTALHGVETNVG
CCCCHHHHHHHHHCCCCCCCCHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHCCCCCCHH
YLRQTLRSDAFRSAQHTTSFLNTFRYAAHTIDVLSPGVQTTVQDYPGRTGYWSIGVPPSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCEEEECCCCCC
PMDGLAFRLANRLVDNSEDKAGLEITLSGPTLHFNCDSVIAVCGAPMEVRLDGEPLAYWR
CHHHHHHHHHHHHHCCCCCCCCEEEEECCCEEEECCCHHHHHCCCCEEEEECCCCEEHHH
AHRVKAGSLLQFGKLVNHGCRAYLAVQGGIRVPDYLGSKSTFTLGHFGGHAGRTLLTGDV
HHHCCCCHHHHHHHHHHCCCEEEEEEECCCCCCHHCCCCCEEEEECCCCCCCCEEEECHH
LHIFEARKDGNGGFEQELPDELVPPYTDSWKIGVLYGPHGAPDFFTEQDIETFFATDWEV
HHHHHHCCCCCCCCCCCCCHHHCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHCCCEEE
HYNSNRTGVRLIGPKPHWARSDGGEAGLHPSNIHDNAYAVGTVDFTGDMPVILGPDGPSL
EECCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCEEECCCCCCC
GGFVCPVTIIQAEFWKMGQLKPGDRVRFHRMSMEQALGLELQQDARIKDLRVPQNVSSEG
CCEEHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHCCEECCCCCCEECCCCCCCCCCC
EQDATDASMPVLHFIPQSDGHVQVVYRQAGDKNLLVEYGPLELDLNLRFRAHALMDWVQK
CCCCCCCCCCEEEEECCCCCEEEEEEEECCCCEEEEEECCEEEEEEEEHHHHHHHHHHHH
TCNDGELKGILDLTPGIRSLQVHFDSRVLPRDKLLEMLVSAEKKLPDIDDMEVPARVVHL
HCCCCCCCEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEE
PLSWDDGATRLAIEKYMQSVRSDAPWCPSNIEFIRRINGLDSIEEVQHILFSANYLVMGL
EECCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCEEEEEC
GDVYLGAPVATPVDPRHRLVTTKYNPARTWTPENAVGIGGAYLCIYGMEGPGGYQFVGRT
CCHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHH
VQMWNRYLQTADFKEGKPWLLRFFDQIRFYPVSESELLKLRKDFITGHFKLKIEETTFSL
HHHHHHHHHCCCCCCCCHHHHHHHHHHEEECCCHHHHHHHHHHHCCCEEEEEEEHHHHHH
KQYNAFLKENAGSISAFKAKQQAAFEAERERWKAQGKAEYVSEVTLEEADAQSELDLPAD
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCC
SQIVSAHVTGTVWKLLVKEGQRVETGDPVVVVESMKMEFSVETPVSGRVRQLFCKEGSHI
CCEEEEHHHHHHHHHHHHCCCEECCCCCEEEEEECEEEEEECCCCCHHHHHHHHCCCCCC
SAGQMLLIVQEE
CCCCEEEEEECC
>Mature Secondary Structure
MFEKVLIANRGAIACRIIRTLRRMGVKSVAIYTEADALSRHVIEADEAYCIGSGVAAESY
CCCCEEEECCCHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHCCCCCEEECCCCHHHHH
LRAEKILEVASHAGANAIHPGYGFLSEKAEFAEQCADHGISFIGPTPHQMRAFGLKHTAR
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHH
KLALQNRVPLLPGTGLLEDLDEALRQAAHIGYPVMLKSTAGGGGIGIRLCWNKEELSANY
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEECHHHHCCCH
ELVKYLAQNNFKDAGLFLEKYVEKARHIEVQIFGDGKGGVIALGERDCSMQRRNQKVIEE
HHHHHHHHCCCCHHHHHHHHHHHHHHEEEEEEEECCCCCEEEECCCCCHHHHHHHHHHHC
TPAPDLPPRVRQALLNAAVRLGKSVNYQSAGTVEYIFDASAAEFYFLEVNTRLQVEHGVT
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCEEEEEEECCEEEECCCCC
EEVTGIDLVEWMVRQAAGDLPPLDSFDIQPQGASLQVRVYAENAVKDFQPSCGILTAAEF
HHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEECCCHHHCCCCCCEEEECCC
PPPSAARVETWVERGVEVSPFYDPMLAKIIVHAPDREQAIARLLQALDVTALHGVETNVG
CCCCHHHHHHHHHCCCCCCCCHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHCCCCCCHH
YLRQTLRSDAFRSAQHTTSFLNTFRYAAHTIDVLSPGVQTTVQDYPGRTGYWSIGVPPSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCEEEECCCCCC
PMDGLAFRLANRLVDNSEDKAGLEITLSGPTLHFNCDSVIAVCGAPMEVRLDGEPLAYWR
CHHHHHHHHHHHHHCCCCCCCCEEEEECCCEEEECCCHHHHHCCCCEEEEECCCCEEHHH
AHRVKAGSLLQFGKLVNHGCRAYLAVQGGIRVPDYLGSKSTFTLGHFGGHAGRTLLTGDV
HHHCCCCHHHHHHHHHHCCCEEEEEEECCCCCCHHCCCCCEEEEECCCCCCCCEEEECHH
LHIFEARKDGNGGFEQELPDELVPPYTDSWKIGVLYGPHGAPDFFTEQDIETFFATDWEV
HHHHHHCCCCCCCCCCCCCHHHCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHCCCEEE
HYNSNRTGVRLIGPKPHWARSDGGEAGLHPSNIHDNAYAVGTVDFTGDMPVILGPDGPSL
EECCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCEEECCCCCCC
GGFVCPVTIIQAEFWKMGQLKPGDRVRFHRMSMEQALGLELQQDARIKDLRVPQNVSSEG
CCEEHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHCCEECCCCCCEECCCCCCCCCCC
EQDATDASMPVLHFIPQSDGHVQVVYRQAGDKNLLVEYGPLELDLNLRFRAHALMDWVQK
CCCCCCCCCCEEEEECCCCCEEEEEEEECCCCEEEEEECCEEEEEEEEHHHHHHHHHHHH
TCNDGELKGILDLTPGIRSLQVHFDSRVLPRDKLLEMLVSAEKKLPDIDDMEVPARVVHL
HCCCCCCCEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEE
PLSWDDGATRLAIEKYMQSVRSDAPWCPSNIEFIRRINGLDSIEEVQHILFSANYLVMGL
EECCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCEEEEEC
GDVYLGAPVATPVDPRHRLVTTKYNPARTWTPENAVGIGGAYLCIYGMEGPGGYQFVGRT
CCHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHH
VQMWNRYLQTADFKEGKPWLLRFFDQIRFYPVSESELLKLRKDFITGHFKLKIEETTFSL
HHHHHHHHHCCCCCCCCHHHHHHHHHHEEECCCHHHHHHHHHHHCCCEEEEEEEHHHHHH
KQYNAFLKENAGSISAFKAKQQAAFEAERERWKAQGKAEYVSEVTLEEADAQSELDLPAD
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCC
SQIVSAHVTGTVWKLLVKEGQRVETGDPVVVVESMKMEFSVETPVSGRVRQLFCKEGSHI
CCEEEEHHHHHHHHHHHHCCCEECCCCCEEEEEECEEEEEECCCCCHHHHHHHHCCCCCC
SAGQMLLIVQEE
CCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]