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The map label for this gene is puuP [H]

Identifier: 82702069

GI number: 82702069

Start: 1087828

End: 1089342

Strand: Direct

Name: puuP [H]

Synonym: Nmul_A0940

Alternate gene names: 82702069

Gene position: 1087828-1089342 (Clockwise)

Preceding gene: 82702068

Following gene: 82702070

Centisome position: 34.16

GC content: 57.49

Gene sequence:

>1515_bases
ATGCCTGTAGAGGAAAGCCGCGGCGCCGTCGTCCCTCCCGCTCCTCCTGCTTCTGCTCCTGGCGTTGTGCTCGTCACCGG
CGACAAGCTTCATCGCAGCATGAGCGTATGGAACAGCTTTACGCTCGGCTTCGCGGTTGTTTCCCCCGTGGTAGGGCTTT
ACGCCATCATCAGCGTTCAGACCACTGTGACAGGAGGCGGATGGTTTGGCGCGCTGGCTACCTGTCTCGTCATGCAGCTG
CTCGTGGCCACGGTCTACGCCGAGCTGTCTTCACAATTCCCCATTGCAGGGGGCGCATACAAATGGGCGCGCCAACTTGG
AGGGGTGACTACCGGGCAATTTGCCGGTGTCATCTACGTCAGTTCCACTATTGCCATGCTCACCACCACCGCCTATACGG
GTGGTGTCTGGCTTGCCCTGTTTTTTGGAGCCGAGAGCGAAACCGGCTCCGCATTCGTGATCTGGGGCGCAGTATTCCTC
CTCCTGTGTACCATTATCAATCTGGTTAACGTCAATATCTTCAAGCTGGTCATCACAATGGGAGTTTATGCGGAAGTTGT
CGGCTCCCTGGGCGTGGCGCTGCTACTGTTCCTGTTTTTCAGGCAGCATTCTTTTTCCGAACTGTTCCAGCATCTCGGCA
CGGGCACCGCGCCAGACCAGTTATCCGCGTTTCTTGCAGCGCTGGCGATCGCCGGATGGGCATTCATCGGTTTTGATGCC
TGCTCCACCATCGCGGAGGAAACGCACGAACCCAAGAGGATGGTGCCGCGCGCCGTCTTCTTCTCTTTATGCATGGTGGG
ATCGGTGGTGCTTTTCAACTCCGCCGCACTGACACTGGCGTTCGATCGCGAGGCACTGATTGCTGCGAGTGCCACTTCCG
ATCCGATTACGCCTGTGATTACCGGCAGTTTTGGCGAGTGGGCGGAAAAGCCATTCTTAGCGATCGTCATGGTCGCATTC
CTGGCTTGCGGCGCCTCGGTGGTGAAATATACCTCGCGTATCGTGTATTCCATGGCCCGCGAAGGCCATATGCCCGCTGT
TCTCAGCCGGCTGGGGCCCGACAAGACGCCCCGTAACGCCGTTATCTGTACCGTATCGCTGGCAGGATTGGGATTGCTGT
TCGGATTGAATGATGGCGCCGTGGCTACCGTGATTGCCTTCGGCACGGGGGGGCTTTACGCCATGTTTTCCATGACGACC
GGCGTGGGTTTATTCACGCGGCTTACCGGGCGCTGGAATCCGGCATTGGGTGAGTTGAAGCTTGGCGTCTGGGGGTTGCT
GATCAACACAGCCGCTTTTATCTGGTCTGTATTCGAACTTGTCAATATTGCCTGGCCGCGTCCCTATGCAGCGGCTCCCG
ATGCCCCGTGGTGGCAGCTTTGGGCGGTACCCCTGGTGCTGGGCAGCATTCTCGGCATTACGGCCCTGTATATCCTGATA
AACAAGATGCGTAAAAAATCCACTTCACACAGCATGCAGAGGGAAGCGAAAACACCGCATCGATCTACGAATTGA

Upstream 100 bases:

>100_bases
CGGCCGGTACTTCCGGGCATCCCGCCTTTAGCGCTTCGGGGAGGAGGCCGGCGCGTCACTGGCAGAACAAAATCTTCCCG
CTTGTTTAGAAAGGGTTATC

Downstream 100 bases:

>100_bases
GCTGATACACCTGAAAAACTATCGTGATGAGGAGAAAGAGAGATGAATCAACCGGATGCATATTTGTGGGAACAACATAT
TCCCGGGGGCTGCCACTGGT

Product: amino acid permease-associated protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 504; Mature: 503

Protein sequence:

>504_residues
MPVEESRGAVVPPAPPASAPGVVLVTGDKLHRSMSVWNSFTLGFAVVSPVVGLYAIISVQTTVTGGGWFGALATCLVMQL
LVATVYAELSSQFPIAGGAYKWARQLGGVTTGQFAGVIYVSSTIAMLTTTAYTGGVWLALFFGAESETGSAFVIWGAVFL
LLCTIINLVNVNIFKLVITMGVYAEVVGSLGVALLLFLFFRQHSFSELFQHLGTGTAPDQLSAFLAALAIAGWAFIGFDA
CSTIAEETHEPKRMVPRAVFFSLCMVGSVVLFNSAALTLAFDREALIAASATSDPITPVITGSFGEWAEKPFLAIVMVAF
LACGASVVKYTSRIVYSMAREGHMPAVLSRLGPDKTPRNAVICTVSLAGLGLLFGLNDGAVATVIAFGTGGLYAMFSMTT
GVGLFTRLTGRWNPALGELKLGVWGLLINTAAFIWSVFELVNIAWPRPYAAAPDAPWWQLWAVPLVLGSILGITALYILI
NKMRKKSTSHSMQREAKTPHRSTN

Sequences:

>Translated_504_residues
MPVEESRGAVVPPAPPASAPGVVLVTGDKLHRSMSVWNSFTLGFAVVSPVVGLYAIISVQTTVTGGGWFGALATCLVMQL
LVATVYAELSSQFPIAGGAYKWARQLGGVTTGQFAGVIYVSSTIAMLTTTAYTGGVWLALFFGAESETGSAFVIWGAVFL
LLCTIINLVNVNIFKLVITMGVYAEVVGSLGVALLLFLFFRQHSFSELFQHLGTGTAPDQLSAFLAALAIAGWAFIGFDA
CSTIAEETHEPKRMVPRAVFFSLCMVGSVVLFNSAALTLAFDREALIAASATSDPITPVITGSFGEWAEKPFLAIVMVAF
LACGASVVKYTSRIVYSMAREGHMPAVLSRLGPDKTPRNAVICTVSLAGLGLLFGLNDGAVATVIAFGTGGLYAMFSMTT
GVGLFTRLTGRWNPALGELKLGVWGLLINTAAFIWSVFELVNIAWPRPYAAAPDAPWWQLWAVPLVLGSILGITALYILI
NKMRKKSTSHSMQREAKTPHRSTN
>Mature_503_residues
PVEESRGAVVPPAPPASAPGVVLVTGDKLHRSMSVWNSFTLGFAVVSPVVGLYAIISVQTTVTGGGWFGALATCLVMQLL
VATVYAELSSQFPIAGGAYKWARQLGGVTTGQFAGVIYVSSTIAMLTTTAYTGGVWLALFFGAESETGSAFVIWGAVFLL
LCTIINLVNVNIFKLVITMGVYAEVVGSLGVALLLFLFFRQHSFSELFQHLGTGTAPDQLSAFLAALAIAGWAFIGFDAC
STIAEETHEPKRMVPRAVFFSLCMVGSVVLFNSAALTLAFDREALIAASATSDPITPVITGSFGEWAEKPFLAIVMVAFL
ACGASVVKYTSRIVYSMAREGHMPAVLSRLGPDKTPRNAVICTVSLAGLGLLFGLNDGAVATVIAFGTGGLYAMFSMTTG
VGLFTRLTGRWNPALGELKLGVWGLLINTAAFIWSVFELVNIAWPRPYAAAPDAPWWQLWAVPLVLGSILGITALYILIN
KMRKKSTSHSMQREAKTPHRSTN

Specific function: Imports putrescine [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI87081869, Length=379, Percent_Identity=23.2189973614776, Blast_Score=74, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17540018, Length=304, Percent_Identity=26.9736842105263, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6321361, Length=539, Percent_Identity=22.8200371057514, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21357367, Length=291, Percent_Identity=27.8350515463918, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 53544; Mature: 53413

Theoretical pI: Translated: 8.56; Mature: 8.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVEESRGAVVPPAPPASAPGVVLVTGDKLHRSMSVWNSFTLGFAVVSPVVGLYAIISVQ
CCCCCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
TTVTGGGWFGALATCLVMQLLVATVYAELSSQFPIAGGAYKWARQLGGVTTGQFAGVIYV
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCHHHEEEEH
SSTIAMLTTTAYTGGVWLALFFGAESETGSAFVIWGAVFLLLCTIINLVNVNIFKLVITM
HHHHHHHHHHHHCCCEEEEEEECCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVYAEVVGSLGVALLLFLFFRQHSFSELFQHLGTGTAPDQLSAFLAALAIAGWAFIGFDA
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
CSTIAEETHEPKRMVPRAVFFSLCMVGSVVLFNSAALTLAFDREALIAASATSDPITPVI
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHEEECCCCCCCCCEE
TGSFGEWAEKPFLAIVMVAFLACGASVVKYTSRIVYSMAREGHMPAVLSRLGPDKTPRNA
ECCCHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCE
VICTVSLAGLGLLFGLNDGAVATVIAFGTGGLYAMFSMTTGVGLFTRLTGRWNPALGELK
EEEEEEHHHHHHHEECCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
LGVWGLLINTAAFIWSVFELVNIAWPRPYAAAPDAPWWQLWAVPLVLGSILGITALYILI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
NKMRKKSTSHSMQREAKTPHRSTN
HHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
PVEESRGAVVPPAPPASAPGVVLVTGDKLHRSMSVWNSFTLGFAVVSPVVGLYAIISVQ
CCCCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
TTVTGGGWFGALATCLVMQLLVATVYAELSSQFPIAGGAYKWARQLGGVTTGQFAGVIYV
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCHHHEEEEH
SSTIAMLTTTAYTGGVWLALFFGAESETGSAFVIWGAVFLLLCTIINLVNVNIFKLVITM
HHHHHHHHHHHHCCCEEEEEEECCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVYAEVVGSLGVALLLFLFFRQHSFSELFQHLGTGTAPDQLSAFLAALAIAGWAFIGFDA
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
CSTIAEETHEPKRMVPRAVFFSLCMVGSVVLFNSAALTLAFDREALIAASATSDPITPVI
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHEEECCCCCCCCCEE
TGSFGEWAEKPFLAIVMVAFLACGASVVKYTSRIVYSMAREGHMPAVLSRLGPDKTPRNA
ECCCHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCE
VICTVSLAGLGLLFGLNDGAVATVIAFGTGGLYAMFSMTTGVGLFTRLTGRWNPALGELK
EEEEEEHHHHHHHEECCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
LGVWGLLINTAAFIWSVFELVNIAWPRPYAAAPDAPWWQLWAVPLVLGSILGITALYILI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
NKMRKKSTSHSMQREAKTPHRSTN
HHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]