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The map label for this gene is mdmC [H]

Identifier: 82702068

GI number: 82702068

Start: 1086595

End: 1087275

Strand: Direct

Name: mdmC [H]

Synonym: Nmul_A0939

Alternate gene names: 82702068

Gene position: 1086595-1087275 (Clockwise)

Preceding gene: 82702065

Following gene: 82702069

Centisome position: 34.12

GC content: 51.4

Gene sequence:

>681_bases
ATGCAATCTCCAACTATTGTAAATCCCTCTCAATTGGACCCGGTAAATCCGGCAATCGAAAAGTATATGCGCAGCCTCGT
GGGTCGGACTGATCATCCTGTGCTGACTGAAATGGAAGCGGTGGCTGCTAAAAACAATTTTCCCATCGTTGGCCGCCTGG
TCGGTGTTTTTCTGGAGACGCTGGCGAAAACGATCGATGCCAAACGTATTTTCGAGTTTGGCAGCGGCTACGGCTACTCG
GCTTACTGGTTCGCAAAAGCAGCCGGGGCGGATGGAAAGGTGATCTGTACCGATGGCGATCCTCAGAACAAGGAAAAGGC
CGAACAGTATCTCAAGTCTGCAGATCTGCTGGAGAGGATCGATTTTCGTACTGGCATCGCGCAGGAGATATTCGGGCAGA
CCGAAGGATTATTCGACATCTGCTACAACGATGCGGACAAGGGGGATTATCCGGAAATCTGGCGTATGGCAAAGGACAGG
ATTCGTCCGCATGGGCTATATATTGCCGATAACGTGCTTTGGCATGGAAGGGTGGCGGTGGAACGTTATGTTGATATTGT
TCCCGGATGGACCGAGGCCATTCTCGAGCACAACCGGTTGATTTTTGGCGATCCCGAATTTGACGCTTTCATAAATCCAA
CGCGGGATGGCGTCGTCGTGGCGCGAAGAAAGTCACAATGA

Upstream 100 bases:

>100_bases
CAGTGCCGCTCACCTTTGACCCCTCATCGTATTGAGCGTAGAGTCGAATAAGGAGCATACGACGAGCACATAATTTCTTG
TTTCTTGAGGAGCGGTGGCC

Downstream 100 bases:

>100_bases
CACGCTATTTTTAATCAGTCTCCAATGCCTAAGCCGCGAATCCTTGGAGAGAGCAGGGCTGCTGAAAAATATCCAAATAA
AATATCGAAGGCTCAAATCC

Product: O-methyltransferase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MQSPTIVNPSQLDPVNPAIEKYMRSLVGRTDHPVLTEMEAVAAKNNFPIVGRLVGVFLETLAKTIDAKRIFEFGSGYGYS
AYWFAKAAGADGKVICTDGDPQNKEKAEQYLKSADLLERIDFRTGIAQEIFGQTEGLFDICYNDADKGDYPEIWRMAKDR
IRPHGLYIADNVLWHGRVAVERYVDIVPGWTEAILEHNRLIFGDPEFDAFINPTRDGVVVARRKSQ

Sequences:

>Translated_226_residues
MQSPTIVNPSQLDPVNPAIEKYMRSLVGRTDHPVLTEMEAVAAKNNFPIVGRLVGVFLETLAKTIDAKRIFEFGSGYGYS
AYWFAKAAGADGKVICTDGDPQNKEKAEQYLKSADLLERIDFRTGIAQEIFGQTEGLFDICYNDADKGDYPEIWRMAKDR
IRPHGLYIADNVLWHGRVAVERYVDIVPGWTEAILEHNRLIFGDPEFDAFINPTRDGVVVARRKSQ
>Mature_226_residues
MQSPTIVNPSQLDPVNPAIEKYMRSLVGRTDHPVLTEMEAVAAKNNFPIVGRLVGVFLETLAKTIDAKRIFEFGSGYGYS
AYWFAKAAGADGKVICTDGDPQNKEKAEQYLKSADLLERIDFRTGIAQEIFGQTEGLFDICYNDADKGDYPEIWRMAKDR
IRPHGLYIADNVLWHGRVAVERYVDIVPGWTEAILEHNRLIFGDPEFDAFINPTRDGVVVARRKSQ

Specific function: 4-O-methyltransferase for the lactone ring of midecamycin and other macrolide antibiotics [H]

COG id: COG4122

COG function: function code R; Predicted O-methyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. Type 3 family [H]

Homologues:

Organism=Homo sapiens, GI31542747, Length=170, Percent_Identity=29.4117647058824, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002935 [H]

Pfam domain/function: PF01596 Methyltransf_3 [H]

EC number: NA

Molecular weight: Translated: 25442; Mature: 25442

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSPTIVNPSQLDPVNPAIEKYMRSLVGRTDHPVLTEMEAVAAKNNFPIVGRLVGVFLET
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHH
LAKTIDAKRIFEFGSGYGYSAYWFAKAAGADGKVICTDGDPQNKEKAEQYLKSADLLERI
HHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHH
DFRTGIAQEIFGQTEGLFDICYNDADKGDYPEIWRMAKDRIRPHGLYIADNVLWHGRVAV
HHHCCHHHHHHCCCCCHHHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEECCEEECCHHHH
ERYVDIVPGWTEAILEHNRLIFGDPEFDAFINPTRDGVVVARRKSQ
HHHHHHCCCHHHHHHHCCCEEECCCCCCCCCCCCCCCEEEEECCCC
>Mature Secondary Structure
MQSPTIVNPSQLDPVNPAIEKYMRSLVGRTDHPVLTEMEAVAAKNNFPIVGRLVGVFLET
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHH
LAKTIDAKRIFEFGSGYGYSAYWFAKAAGADGKVICTDGDPQNKEKAEQYLKSADLLERI
HHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHH
DFRTGIAQEIFGQTEGLFDICYNDADKGDYPEIWRMAKDRIRPHGLYIADNVLWHGRVAV
HHHCCHHHHHHCCCCCHHHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEECCEEECCHHHH
ERYVDIVPGWTEAILEHNRLIFGDPEFDAFINPTRDGVVVARRKSQ
HHHHHHCCCHHHHHHHCCCEEECCCCCCCCCCCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1629172 [H]