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The map label for this gene is yusV [H]

Identifier: 82702012

GI number: 82702012

Start: 1003698

End: 1004495

Strand: Reverse

Name: yusV [H]

Synonym: Nmul_A0883

Alternate gene names: 82702012

Gene position: 1004495-1003698 (Counterclockwise)

Preceding gene: 82702013

Following gene: 82702011

Centisome position: 31.55

GC content: 60.28

Gene sequence:

>798_bases
ATGATTCTACAAACAAGAAATCTGACCCTGCAGCATCCTGGCACGATCCTGTGCCGCGACTTGAACCTGACCGTCAACCC
GGGGGAATGCTGGGCAATATTGGGCCGGAACGGCTGCGGCAAGACGACCTTGATACATGCCCTGGGGGGGCTGCACCCGC
CGAAGGGGGGACAGGATGCGGGGCAGGATCCGTCCGTAACCATGGCGGGGAAGGCGCTTGGGCAGTGGTCCCGGCGGGAG
CTTGCCCGCAATCTCGGCATTCTGTTGCAGGATGAGCCCGGCGAGTTCTGGGGTACCGTGCATGAATACGTGCTGCTCGG
CCGGCATCCTCATGCAGCCAGCCTGGTCGGCTGGCAGGCGGTCGACCTCGAGATGACAGCTCGCGCTATCGAGCAAATGG
AACTGGCCGGCCTTGCCGACCGTCTACTGGTCACGCTTTCCGGCGGCGAGCGCCAGCGCGCGCGTATCGCCCTGCTGCTT
GCCCAGTCGCCCAAATGCTATCTGCTGGATGAGCCCTTGCAACACCTCGATCTGCGCCATCAACTCGGGACCATGATCCT
GTTCAGCGAATTGGCGAAGCGAGGCAGTTCCATCGCAATGGTGCTGCACGATATAGGCTGGGCAGTGAAATTCTGCAACC
ACGCATTGCTGTTGTTCGACGACGGCCATGCCATGAGCGGCAGTATAGACGAGGTGCTCAAGCGCGATAATCTTGAAGCG
CTTTATCACTGTAATCTGGAGGAGTTCATCGCAGGCAGGCAGCACCATTTCTTCCCGCAAGCGGTGCCGAGTGTATAA

Upstream 100 bases:

>100_bases
GCCATCTCCATCGCTGGCTGGGAAGGAAAAGCGAATACCTGAGGGCATAAAAAGAATGATCTGGATGCGGTTCTTCATCG
CGGATTTTTCGAGTTCGTGA

Downstream 100 bases:

>100_bases
TCTGGAATTTCAGGCATACTTTTTCTCAGCAGCAATTCTTCCGCGCTTTTTCCAGCAAGGGTCGTGGACGGCAGTGGCTG
TTTGCCCTCACTTGATCTTC

Product: ABC transporter-like protein

Products: ADP; phosphate; iron (III) hydroxamate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MILQTRNLTLQHPGTILCRDLNLTVNPGECWAILGRNGCGKTTLIHALGGLHPPKGGQDAGQDPSVTMAGKALGQWSRRE
LARNLGILLQDEPGEFWGTVHEYVLLGRHPHAASLVGWQAVDLEMTARAIEQMELAGLADRLLVTLSGGERQRARIALLL
AQSPKCYLLDEPLQHLDLRHQLGTMILFSELAKRGSSIAMVLHDIGWAVKFCNHALLLFDDGHAMSGSIDEVLKRDNLEA
LYHCNLEEFIAGRQHHFFPQAVPSV

Sequences:

>Translated_265_residues
MILQTRNLTLQHPGTILCRDLNLTVNPGECWAILGRNGCGKTTLIHALGGLHPPKGGQDAGQDPSVTMAGKALGQWSRRE
LARNLGILLQDEPGEFWGTVHEYVLLGRHPHAASLVGWQAVDLEMTARAIEQMELAGLADRLLVTLSGGERQRARIALLL
AQSPKCYLLDEPLQHLDLRHQLGTMILFSELAKRGSSIAMVLHDIGWAVKFCNHALLLFDDGHAMSGSIDEVLKRDNLEA
LYHCNLEEFIAGRQHHFFPQAVPSV
>Mature_265_residues
MILQTRNLTLQHPGTILCRDLNLTVNPGECWAILGRNGCGKTTLIHALGGLHPPKGGQDAGQDPSVTMAGKALGQWSRRE
LARNLGILLQDEPGEFWGTVHEYVLLGRHPHAASLVGWQAVDLEMTARAIEQMELAGLADRLLVTLSGGERQRARIALLL
AQSPKCYLLDEPLQHLDLRHQLGTMILFSELAKRGSSIAMVLHDIGWAVKFCNHALLLFDDGHAMSGSIDEVLKRDNLEA
LYHCNLEEFIAGRQHHFFPQAVPSV

Specific function: Provides the ATPase subunit for at least 2 ABC transporter complexes; YfiYZ/YfhA/YusV involved in import of the iron-hydroxamate siderophores schizokinen, arthrobactin and corprogen (Probable), and FeuABC/YusV involved in import of the catecholate siderop

COG id: COG1120

COG function: function code PH; ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI11967969, Length=196, Percent_Identity=29.5918367346939, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI105990541, Length=231, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI9665248, Length=237, Percent_Identity=27.4261603375527, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI45446740, Length=261, Percent_Identity=25.2873563218391, Blast_Score=64, Evalue=1e-10,
Organism=Homo sapiens, GI47078218, Length=261, Percent_Identity=25.2873563218391, Blast_Score=64, Evalue=1e-10,
Organism=Escherichia coli, GI1786345, Length=238, Percent_Identity=36.9747899159664, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1786803, Length=243, Percent_Identity=34.9794238683128, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI1790739, Length=260, Percent_Identity=35.3846153846154, Blast_Score=137, Evalue=9e-34,
Organism=Escherichia coli, GI1786563, Length=225, Percent_Identity=33.3333333333333, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1789891, Length=231, Percent_Identity=30.3030303030303, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788225, Length=253, Percent_Identity=28.4584980237154, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1790525, Length=223, Percent_Identity=28.2511210762332, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI87081791, Length=238, Percent_Identity=29.4117647058824, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788002, Length=237, Percent_Identity=29.957805907173, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87081834, Length=206, Percent_Identity=32.0388349514563, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87081709, Length=227, Percent_Identity=26.431718061674, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI48994997, Length=246, Percent_Identity=30.0813008130081, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1789873, Length=209, Percent_Identity=28.7081339712919, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1787029, Length=249, Percent_Identity=28.1124497991968, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI48994883, Length=211, Percent_Identity=27.0142180094787, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1790544, Length=238, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1786398, Length=274, Percent_Identity=26.2773722627737, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1787089, Length=210, Percent_Identity=30, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1786253, Length=216, Percent_Identity=30.0925925925926, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1788761, Length=272, Percent_Identity=27.9411764705882, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786975, Length=225, Percent_Identity=28.4444444444444, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788210, Length=230, Percent_Identity=27.8260869565217, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790190, Length=254, Percent_Identity=23.6220472440945, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787712, Length=243, Percent_Identity=27.5720164609054, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787500, Length=232, Percent_Identity=28.8793103448276, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788897, Length=221, Percent_Identity=25.3393665158371, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1786703, Length=218, Percent_Identity=30.7339449541284, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1786872, Length=197, Percent_Identity=27.4111675126904, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1788472, Length=220, Percent_Identity=23.1818181818182, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787164, Length=218, Percent_Identity=27.5229357798165, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786319, Length=214, Percent_Identity=25.7009345794392, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1787105, Length=198, Percent_Identity=31.8181818181818, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI71984940, Length=160, Percent_Identity=35.625, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17567269, Length=189, Percent_Identity=32.8042328042328, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17567265, Length=185, Percent_Identity=31.8918918918919, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17555800, Length=188, Percent_Identity=29.7872340425532, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI115535101, Length=188, Percent_Identity=32.4468085106383, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17558664, Length=201, Percent_Identity=26.865671641791, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI25146777, Length=226, Percent_Identity=23.8938053097345, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24659289, Length=260, Percent_Identity=27.6923076923077, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24653245, Length=242, Percent_Identity=28.099173553719, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281363262, Length=243, Percent_Identity=27.9835390946502, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24661270, Length=190, Percent_Identity=27.8947368421053, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21355589, Length=190, Percent_Identity=27.8947368421053, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 29203; Mature: 29203

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILQTRNLTLQHPGTILCRDLNLTVNPGECWAILGRNGCGKTTLIHALGGLHPPKGGQDA
CEEECCCEEEECCCEEEEEECEEEECCCCEEEEECCCCCCHHHHHHHHCCCCCCCCCCCC
GQDPSVTMAGKALGQWSRRELARNLGILLQDEPGEFWGTVHEYVLLGRHPHAASLVGWQA
CCCCCEEEHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHCCCCCCCHHHCCEEE
VDLEMTARAIEQMELAGLADRLLVTLSGGERQRARIALLLAQSPKCYLLDEPLQHLDLRH
ECHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEEECCCCEEEECCHHHHHHHHH
QLGTMILFSELAKRGSSIAMVLHDIGWAVKFCNHALLLFDDGHAMSGSIDEVLKRDNLEA
HHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHCCCCE
LYHCNLEEFIAGRQHHFFPQAVPSV
EEECCHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MILQTRNLTLQHPGTILCRDLNLTVNPGECWAILGRNGCGKTTLIHALGGLHPPKGGQDA
CEEECCCEEEECCCEEEEEECEEEECCCCEEEEECCCCCCHHHHHHHHCCCCCCCCCCCC
GQDPSVTMAGKALGQWSRRELARNLGILLQDEPGEFWGTVHEYVLLGRHPHAASLVGWQA
CCCCCEEEHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHCCCCCCCHHHCCEEE
VDLEMTARAIEQMELAGLADRLLVTLSGGERQRARIALLLAQSPKCYLLDEPLQHLDLRH
ECHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEEECCCCEEEECCHHHHHHHHH
QLGTMILFSELAKRGSSIAMVLHDIGWAVKFCNHALLLFDDGHAMSGSIDEVLKRDNLEA
HHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHCCCCE
LYHCNLEEFIAGRQHHFFPQAVPSV
EEECCHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron (III) hydroxamate [Periplasm]; H2O [C]

Specific reaction: ATP + iron (III) hydroxamate [Periplasm] + H2O = ADP + phosphate + iron (III) hydroxamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]