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The map label for this gene is recG [H]

Identifier: 82702013

GI number: 82702013

Start: 1004546

End: 1006624

Strand: Reverse

Name: recG [H]

Synonym: Nmul_A0884

Alternate gene names: 82702013

Gene position: 1006624-1004546 (Counterclockwise)

Preceding gene: 82702014

Following gene: 82702012

Centisome position: 31.61

GC content: 56.81

Gene sequence:

>2079_bases
ATGCAGTCGCTCGCCACCTCTCCCATCAGCGGGACAATCAGGGACAAGCTCCTCAAACTCGGCATTACCGATGCTTCAAG
CCTGATACTGCATTTGCCGTTTCGCTATGAGGACGAGACGCACCTCTACCCCATCAGTGATGTACCTGCGGATCGAACAG
TGCAGGTCGAAGGCACGATCATCCGAAGCGAAGTCATGTACCGGCCACGGCGGCAATTGGTATGCCAGGTGGAGGATGGA
ACAGGTGTTTTGTTCATGCGCTTCCTGAATTTTTACGGGAGTCAGATAAAAGCATATTCAGTGGGTACGCGGGTGCGCTT
GCTGGGAGAGGCCCGTCCCGGCTTTTTCGGTGTTGAAATGGTTCATCCCAAATGCCGGATTTTGCGCGGGAATGAACCCC
TGCCGGACGCTCTCACTCCGATTTACCCCTCTACGGCGGGACTTCCTTCCGAAGCACTGCGCAAACTGATTTCCCGGGTC
CTGCAAACAGGAGAGGGCGGAAACCAGGAGGGAACTCTCTGCGAAACGCTGCCAGAGTCCATACGCAAACGCTGCCAGCT
TCAGGGTTTCAAGGACAGTGTGCTATTCCTGCACCAACCCCCACCAAATGCGTCGCCTGCTCTATTGCGGGAGCGCACTC
ATCCCGCTTGGCAGCGGATCAAATTCGATGAATTGCTGGCGCAGCAATTGTCGATGCGGGTCCATTATCAGCAGCGGCGC
AACGGCAGCGCCCCTGTTTTGATAGCAAAAAACGATTTGACCAGAGCGCTGCTGAAGTTGCTGCCTTTCGATCTCACTCA
AGCCCAGAAGAAGGCTTTCGCCGAAATCAGCCGCGATCTGACGGAGCCCCATCCCATGCAACGCCTGTTGCAGGGTGACG
TGGGGAGCGGCAAAACGATCGTTGCCACACTGGCTGTGCTGCAATCGATTGAAAATAATTTTCAGGCAGCACTGATGGCG
CCGACCGAGATTCTTGCGGAGCAGCATTATCGGAAACTCTCCACATGGCTTGCCCCCCTGCTGGAGCCGCGTGGGCTGCG
GATTGCGTGGCTCGGCGGCAATCAGAAAAAGAAGGAACGGGAAACCACGCTTGCCGATATTGCTGCCGGCAACGCCCTGC
TTGCCATCGGGACACATGCATTGTTCCAGAACCAAGTGGAGTTTGACAGGCTGGGACTTGTGGTTATTGACGAACAACAT
CGCTTTGGTGTTCACCAGCGGCTGGCATTGCGAGAAAAAGGAGCCGGAGCGTACGCCATGCCACATCAGTTGATGATGAG
CGCAACACCCATTCCACGCACCCTTTCGATGAGCTATTACGCTGATCTGGATGTGTCCGTAATAGACGAAATGCCGCCCG
GACGCGCACCGGTGGTAACCAAGCTTGTCGCCGACGCCCGTCGCGACGAGGTAACGGCGCGCGTACGGGAAGCCTGCCGT
GAGGGAAAGCAGGCCTACTGGGTATGTCCGTTGATCCAGGAGTCTGAGGCATTGCAGCTCAAGACCGCGCTGGAAACCCA
CCAGGGGCTGACCGGGACTTTTCCGGAATTGAGAATCGGCCTGGTGCATGGCAGGCTTTCATTTCAGGAGAAATCCGATG
TGATGGAAGCATTTGCGCGAGGTGAAATCCATCTCCTCGTAGCGACAACAGTGATCGAAGTGGGCGTGGATGTGCCCAAT
GCGTCACTGATGGTGATCGAGCATGCAGAACGCATGGGCCTTGCGCAACTGCACCAACTACGCGGACGGATCGGACGAGG
GGCGGCCGGTAGCGTATGCATATTGATGTATCAGCCCCCTCTCTCCCCAAACGCGCGCGAGCGGCTCAAGATTATTTTTG
AAAACACGGATGGCTTTGAAATAGCCCGCCAGGATCTGCAACTGCGGGGGCCCGGCGAATTCCTGGGTGCGCGTCAGAGC
GGCCTGCCCATGCTGCGCTTCGCTGATCTGGAACGGGATAAAGACCTGCTCGATACGGCACGGACGATCGCCGTGGAATT
GCTGCGTGATTATCCGGAAGCGGCGAAACGCCATCTCCATCGCTGGCTGGGAAGGAAAAGCGAATACCTGAGGGCATAA

Upstream 100 bases:

>100_bases
CACTGGTGGAGATCGATGCGGTGCTGGTGGTGCCCGCGTGAGGACTGAGGGGTGATACAGGAACCCGCGCGCTAGTCCAA
AGGATGCATTTCCACGACGG

Downstream 100 bases:

>100_bases
AAAGAATGATCTGGATGCGGTTCTTCATCGCGGATTTTTCGAGTTCGTGAATGATTCTACAAACAAGAAATCTGACCCTG
CAGCATCCTGGCACGATCCT

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 692; Mature: 692

Protein sequence:

>692_residues
MQSLATSPISGTIRDKLLKLGITDASSLILHLPFRYEDETHLYPISDVPADRTVQVEGTIIRSEVMYRPRRQLVCQVEDG
TGVLFMRFLNFYGSQIKAYSVGTRVRLLGEARPGFFGVEMVHPKCRILRGNEPLPDALTPIYPSTAGLPSEALRKLISRV
LQTGEGGNQEGTLCETLPESIRKRCQLQGFKDSVLFLHQPPPNASPALLRERTHPAWQRIKFDELLAQQLSMRVHYQQRR
NGSAPVLIAKNDLTRALLKLLPFDLTQAQKKAFAEISRDLTEPHPMQRLLQGDVGSGKTIVATLAVLQSIENNFQAALMA
PTEILAEQHYRKLSTWLAPLLEPRGLRIAWLGGNQKKKERETTLADIAAGNALLAIGTHALFQNQVEFDRLGLVVIDEQH
RFGVHQRLALREKGAGAYAMPHQLMMSATPIPRTLSMSYYADLDVSVIDEMPPGRAPVVTKLVADARRDEVTARVREACR
EGKQAYWVCPLIQESEALQLKTALETHQGLTGTFPELRIGLVHGRLSFQEKSDVMEAFARGEIHLLVATTVIEVGVDVPN
ASLMVIEHAERMGLAQLHQLRGRIGRGAAGSVCILMYQPPLSPNARERLKIIFENTDGFEIARQDLQLRGPGEFLGARQS
GLPMLRFADLERDKDLLDTARTIAVELLRDYPEAAKRHLHRWLGRKSEYLRA

Sequences:

>Translated_692_residues
MQSLATSPISGTIRDKLLKLGITDASSLILHLPFRYEDETHLYPISDVPADRTVQVEGTIIRSEVMYRPRRQLVCQVEDG
TGVLFMRFLNFYGSQIKAYSVGTRVRLLGEARPGFFGVEMVHPKCRILRGNEPLPDALTPIYPSTAGLPSEALRKLISRV
LQTGEGGNQEGTLCETLPESIRKRCQLQGFKDSVLFLHQPPPNASPALLRERTHPAWQRIKFDELLAQQLSMRVHYQQRR
NGSAPVLIAKNDLTRALLKLLPFDLTQAQKKAFAEISRDLTEPHPMQRLLQGDVGSGKTIVATLAVLQSIENNFQAALMA
PTEILAEQHYRKLSTWLAPLLEPRGLRIAWLGGNQKKKERETTLADIAAGNALLAIGTHALFQNQVEFDRLGLVVIDEQH
RFGVHQRLALREKGAGAYAMPHQLMMSATPIPRTLSMSYYADLDVSVIDEMPPGRAPVVTKLVADARRDEVTARVREACR
EGKQAYWVCPLIQESEALQLKTALETHQGLTGTFPELRIGLVHGRLSFQEKSDVMEAFARGEIHLLVATTVIEVGVDVPN
ASLMVIEHAERMGLAQLHQLRGRIGRGAAGSVCILMYQPPLSPNARERLKIIFENTDGFEIARQDLQLRGPGEFLGARQS
GLPMLRFADLERDKDLLDTARTIAVELLRDYPEAAKRHLHRWLGRKSEYLRA
>Mature_692_residues
MQSLATSPISGTIRDKLLKLGITDASSLILHLPFRYEDETHLYPISDVPADRTVQVEGTIIRSEVMYRPRRQLVCQVEDG
TGVLFMRFLNFYGSQIKAYSVGTRVRLLGEARPGFFGVEMVHPKCRILRGNEPLPDALTPIYPSTAGLPSEALRKLISRV
LQTGEGGNQEGTLCETLPESIRKRCQLQGFKDSVLFLHQPPPNASPALLRERTHPAWQRIKFDELLAQQLSMRVHYQQRR
NGSAPVLIAKNDLTRALLKLLPFDLTQAQKKAFAEISRDLTEPHPMQRLLQGDVGSGKTIVATLAVLQSIENNFQAALMA
PTEILAEQHYRKLSTWLAPLLEPRGLRIAWLGGNQKKKERETTLADIAAGNALLAIGTHALFQNQVEFDRLGLVVIDEQH
RFGVHQRLALREKGAGAYAMPHQLMMSATPIPRTLSMSYYADLDVSVIDEMPPGRAPVVTKLVADARRDEVTARVREACR
EGKQAYWVCPLIQESEALQLKTALETHQGLTGTFPELRIGLVHGRLSFQEKSDVMEAFARGEIHLLVATTVIEVGVDVPN
ASLMVIEHAERMGLAQLHQLRGRIGRGAAGSVCILMYQPPLSPNARERLKIIFENTDGFEIARQDLQLRGPGEFLGARQS
GLPMLRFADLERDKDLLDTARTIAVELLRDYPEAAKRHLHRWLGRKSEYLRA

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=695, Percent_Identity=47.6258992805755, Blast_Score=610, Evalue=1e-176,
Organism=Escherichia coli, GI1787357, Length=390, Percent_Identity=37.9487179487179, Blast_Score=227, Evalue=2e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 77408; Mature: 77408

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSLATSPISGTIRDKLLKLGITDASSLILHLPFRYEDETHLYPISDVPADRTVQVEGTI
CCCCCCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCEEEECCCCCCCCEEEEECEE
IRSEVMYRPRRQLVCQVEDGTGVLFMRFLNFYGSQIKAYSVGTRVRLLGEARPGFFGVEM
EHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEECCCEEEEEECCCCCEEEEEE
VHPKCRILRGNEPLPDALTPIYPSTAGLPSEALRKLISRVLQTGEGGNQEGTLCETLPES
ECCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
IRKRCQLQGFKDSVLFLHQPPPNASPALLRERTHPAWQRIKFDELLAQQLSMRVHYQQRR
HHHHHHCCCCCCCEEEEECCCCCCCHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHC
NGSAPVLIAKNDLTRALLKLLPFDLTQAQKKAFAEISRDLTEPHPMQRLLQGDVGSGKTI
CCCCCEEEECCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCHHH
VATLAVLQSIENNFQAALMAPTEILAEQHYRKLSTWLAPLLEPRGLRIAWLGGNQKKKER
HHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHH
ETTLADIAAGNALLAIGTHALFQNQVEFDRLGLVVIDEQHRFGVHQRLALREKGAGAYAM
HHHHHHHHCCCEEEEEHHHHHHHCCCCHHHCCEEEEECCHHCCHHHHHHHHHCCCCCCCC
PHQLMMSATPIPRTLSMSYYADLDVSVIDEMPPGRAPVVTKLVADARRDEVTARVREACR
CHHHHHCCCCCCCEEEEEEEECCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EGKQAYWVCPLIQESEALQLKTALETHQGLTGTFPELRIGLVHGRLSFQEKSDVMEAFAR
CCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCHHEEEEEECCCCCHHHHHHHHHHHC
GEIHLLVATTVIEVGVDVPNASLMVIEHAERMGLAQLHQLRGRIGRGAAGSVCILMYQPP
CCEEEEEEEHHHHHCCCCCCCCEEEEECHHHCCHHHHHHHHHHCCCCCCCCEEEEEECCC
LSPNARERLKIIFENTDGFEIARQDLQLRGPGEFLGARQSGLPMLRFADLERDKDLLDTA
CCCCHHHEEEEEEECCCCHHHHHHCCCCCCCHHHHCCCCCCCCEEEECCCCCCHHHHHHH
RTIAVELLRDYPEAAKRHLHRWLGRKSEYLRA
HHHHHHHHHHCHHHHHHHHHHHHCCCHHHHCC
>Mature Secondary Structure
MQSLATSPISGTIRDKLLKLGITDASSLILHLPFRYEDETHLYPISDVPADRTVQVEGTI
CCCCCCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCEEEECCCCCCCCEEEEECEE
IRSEVMYRPRRQLVCQVEDGTGVLFMRFLNFYGSQIKAYSVGTRVRLLGEARPGFFGVEM
EHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEECCCEEEEEECCCCCEEEEEE
VHPKCRILRGNEPLPDALTPIYPSTAGLPSEALRKLISRVLQTGEGGNQEGTLCETLPES
ECCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
IRKRCQLQGFKDSVLFLHQPPPNASPALLRERTHPAWQRIKFDELLAQQLSMRVHYQQRR
HHHHHHCCCCCCCEEEEECCCCCCCHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHC
NGSAPVLIAKNDLTRALLKLLPFDLTQAQKKAFAEISRDLTEPHPMQRLLQGDVGSGKTI
CCCCCEEEECCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCHHH
VATLAVLQSIENNFQAALMAPTEILAEQHYRKLSTWLAPLLEPRGLRIAWLGGNQKKKER
HHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHH
ETTLADIAAGNALLAIGTHALFQNQVEFDRLGLVVIDEQHRFGVHQRLALREKGAGAYAM
HHHHHHHHCCCEEEEEHHHHHHHCCCCHHHCCEEEEECCHHCCHHHHHHHHHCCCCCCCC
PHQLMMSATPIPRTLSMSYYADLDVSVIDEMPPGRAPVVTKLVADARRDEVTARVREACR
CHHHHHCCCCCCCEEEEEEEECCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EGKQAYWVCPLIQESEALQLKTALETHQGLTGTFPELRIGLVHGRLSFQEKSDVMEAFAR
CCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCHHEEEEEECCCCCHHHHHHHHHHHC
GEIHLLVATTVIEVGVDVPNASLMVIEHAERMGLAQLHQLRGRIGRGAAGSVCILMYQPP
CCEEEEEEEHHHHHCCCCCCCCEEEEECHHHCCHHHHHHHHHHCCCCCCCCEEEEEECCC
LSPNARERLKIIFENTDGFEIARQDLQLRGPGEFLGARQSGLPMLRFADLERDKDLLDTA
CCCCHHHEEEEEEECCCCHHHHHHCCCCCCCHHHHCCCCCCCCEEEECCCCCCHHHHHHH
RTIAVELLRDYPEAAKRHLHRWLGRKSEYLRA
HHHHHHHHHHCHHHHHHHHHHHHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]