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The map label for this gene is apr [H]

Identifier: 82701974

GI number: 82701974

Start: 956922

End: 957863

Strand: Reverse

Name: apr [H]

Synonym: Nmul_A0844

Alternate gene names: 82701974

Gene position: 957863-956922 (Counterclockwise)

Preceding gene: 82701984

Following gene: 82701973

Centisome position: 30.08

GC content: 58.7

Gene sequence:

>942_bases
TTGCTCCCCACCGAACTCGTGAAACTCCCGGCGTTGATGCAACGCACCAGCGGCAGTCCGGAAGTCAGGATTGGACTCAT
CGACGGCCCTGTCTTCACCCAACACGCCGACCTCGTTCAGGGACAACTTATGGAGATTGGTGGACGCAACGCGGCGAGTT
GCACTCAGACAGATAGCGGAGCGTGCCTGCATGGCACCTTTGTCGCCGGTATTCTGGCTGCCAGACGCACTTCCTCCGCA
CCTGCCATCTGTCCCAACTGCACCTTGCTCATTCGCCCCATTTTTTCTGAGGCCACTTTCGGCCGTGAGCACATGCCCAG
CGCAACGCCTCAGGAGCTGGCAACGGCAATTTTTGACTGTATCAACGCGGGTGCGCGCGTCATCAACTTAAGCCTTGCCC
TGGCGCGACCTTCCACCAGGGGAGAGAAGGTATTGGATGAAGCCTTCACTCAGGCGCTAAAGCAGGGCGTATTGATCGTT
GCGGCAGCCGGCAATCAAGGCACTTTGGGCGGTTCCGTCATCACCCGCCACCCTTGGGTCATTCCTGTGGTGGCCTGCGA
TCTGCGTGGCCGTCCGATCAATGAATCGAACCTTGGCGGCAGTATCGGCATGCGGGGTTTGAGCGCCCCGGGCGAGAACA
TCACCAGTCTGGACTCTGGCGGCCAGGCCATTACCTTAAGCGGCACAAGTATGGCCGTGCCTTTTGTTACCGGCGCCATC
GCGCTGTTGTGGTCGGAATTTCCCGATGCAACGGTTGCACAGATCAAACTCGCCATCATGCGCCAACCCCAAACCTTCCG
CCAAGGCAGCTTCATGCAAGGCGGCTTCCTGTCTACCCGAAGCTACGGACCACGACGCGCTTCGATAGTGCCGCCCCTGC
TCGATGCAGAAGCAGCCTATCAAATGCTTTCTGCAATGAGTACAAGGAGGCAAACAGCATGA

Upstream 100 bases:

>100_bases
GTGAAGTTCCCAATCTGCTTTGACAGCTTGAATTCCATCACCTAAATTGAAGCAATTAACCTTCGTCGAAGGGTTATAAC
TTTGATTCAGGAGAACGCTT

Downstream 100 bases:

>100_bases
TCAAGGATGAGGGCAAGAGCGTCCCAGACAACAAGAGCAAACAGGCAACCTACCACGTCCGCCTGCCCGGCTTCATTACC
GATGAGGAAATCCGGCTGGG

Product: peptidase S8/S53 subtilisin kexin sedolisin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MLPTELVKLPALMQRTSGSPEVRIGLIDGPVFTQHADLVQGQLMEIGGRNAASCTQTDSGACLHGTFVAGILAARRTSSA
PAICPNCTLLIRPIFSEATFGREHMPSATPQELATAIFDCINAGARVINLSLALARPSTRGEKVLDEAFTQALKQGVLIV
AAAGNQGTLGGSVITRHPWVIPVVACDLRGRPINESNLGGSIGMRGLSAPGENITSLDSGGQAITLSGTSMAVPFVTGAI
ALLWSEFPDATVAQIKLAIMRQPQTFRQGSFMQGGFLSTRSYGPRRASIVPPLLDAEAAYQMLSAMSTRRQTA

Sequences:

>Translated_313_residues
MLPTELVKLPALMQRTSGSPEVRIGLIDGPVFTQHADLVQGQLMEIGGRNAASCTQTDSGACLHGTFVAGILAARRTSSA
PAICPNCTLLIRPIFSEATFGREHMPSATPQELATAIFDCINAGARVINLSLALARPSTRGEKVLDEAFTQALKQGVLIV
AAAGNQGTLGGSVITRHPWVIPVVACDLRGRPINESNLGGSIGMRGLSAPGENITSLDSGGQAITLSGTSMAVPFVTGAI
ALLWSEFPDATVAQIKLAIMRQPQTFRQGSFMQGGFLSTRSYGPRRASIVPPLLDAEAAYQMLSAMSTRRQTA
>Mature_313_residues
MLPTELVKLPALMQRTSGSPEVRIGLIDGPVFTQHADLVQGQLMEIGGRNAASCTQTDSGACLHGTFVAGILAARRTSSA
PAICPNCTLLIRPIFSEATFGREHMPSATPQELATAIFDCINAGARVINLSLALARPSTRGEKVLDEAFTQALKQGVLIV
AAAGNQGTLGGSVITRHPWVIPVVACDLRGRPINESNLGGSIGMRGLSAPGENITSLDSGGQAITLSGTSMAVPFVTGAI
ALLWSEFPDATVAQIKLAIMRQPQTFRQGSFMQGGFLSTRSYGPRRASIVPPLLDAEAAYQMLSAMSTRRQTA

Specific function: Subtilisin is an extracellular alkaline serine protease, it catalyzes the hydrolysis of proteins and peptide amides [H]

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500 [H]

Pfam domain/function: PF00082 Peptidase_S8 [H]

EC number: =3.4.21.62 [H]

Molecular weight: Translated: 32869; Mature: 32869

Theoretical pI: Translated: 8.62; Mature: 8.62

Prosite motif: PS00137 SUBTILASE_HIS ; PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPTELVKLPALMQRTSGSPEVRIGLIDGPVFTQHADLVQGQLMEIGGRNAASCTQTDSG
CCCHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
ACLHGTFVAGILAARRTSSAPAICPNCTLLIRPIFSEATFGREHMPSATPQELATAIFDC
CEEHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEHHHHHHCCHHHCCCCCHHHHHHHHHHH
INAGARVINLSLALARPSTRGEKVLDEAFTQALKQGVLIVAAAGNQGTLGGSVITRHPWV
HHCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCEEECCCCE
IPVVACDLRGRPINESNLGGSIGMRGLSAPGENITSLDSGGQAITLSGTSMAVPFVTGAI
EEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEHHHHHHHH
ALLWSEFPDATVAQIKLAIMRQPQTFRQGSFMQGGFLSTRSYGPRRASIVPPLLDAEAAY
HHHHHHCCCCHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
QMLSAMSTRRQTA
HHHHHHHHHHCCC
>Mature Secondary Structure
MLPTELVKLPALMQRTSGSPEVRIGLIDGPVFTQHADLVQGQLMEIGGRNAASCTQTDSG
CCCHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
ACLHGTFVAGILAARRTSSAPAICPNCTLLIRPIFSEATFGREHMPSATPQELATAIFDC
CEEHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEHHHHHHCCHHHCCCCCHHHHHHHHHHH
INAGARVINLSLALARPSTRGEKVLDEAFTQALKQGVLIVAAAGNQGTLGGSVITRHPWV
HHCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCEEECCCCE
IPVVACDLRGRPINESNLGGSIGMRGLSAPGENITSLDSGGQAITLSGTSMAVPFVTGAI
EEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEHHHHHHHH
ALLWSEFPDATVAQIKLAIMRQPQTFRQGSFMQGGFLSTRSYGPRRASIVPPLLDAEAAY
HHHHHHCCCCHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
QMLSAMSTRRQTA
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6420308; 9826175 [H]