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The map label for this gene is nreC [H]

Identifier: 82701861

GI number: 82701861

Start: 848727

End: 849380

Strand: Direct

Name: nreC [H]

Synonym: Nmul_A0728

Alternate gene names: 82701861

Gene position: 848727-849380 (Clockwise)

Preceding gene: 82701860

Following gene: 82701862

Centisome position: 26.65

GC content: 52.45

Gene sequence:

>654_bases
ATGGCAGCTTCGAAAGCACAGGTAATGCTGGTGGACGATCATGCCATGTTGCGGCACGGCATGGCAATGCTTATCAATCT
TGAGCCAGATATGGAGGTATTTGCAGAGGCCGGTGACGGCGACGAAGCGCTCGCCACGCTCAAGGCAGGACATCATGCCG
ATATCGTTTTAATGGATGTATCCCTCAAGACTCTCTCCGGTTTTGAGGTCATAAAAAGCATACACACCCTGCTCCCCGCA
CTACCCGTACTCGTCGTCTCCATGCACGATGAAGGCGTGTATGCGGAACGCGCTTTGCGGGCCGGGGCGCGCGGCTACGT
GATGAAGCAGGAGCCGGGTGAAGTGCTGGTAACCGCTATCCACGAGGTATTAAAGGGAAATATTTATTTGAGCAAGCCCA
TGCATGCCAAGCTGTTGAATCGGGTCGCAGGCGGAAATTCGGAGCCAGAGCCTTTGATTAACAGCCTGACCCCCAGTGAG
TTTGAGGTACTGCATTTGATCGGATCCGGACATAGCAGTCAGGAAATCGCCAAATTGCTTAGCCGCAGTATTAAAACTAT
CGAAACGCACCGCTTCAACATTCGTACCAAATTGAACTTGAAAGACGGCGCCGATTTGATACGTTATGCCACCCACTGGA
GCGAAGCCCAATAG

Upstream 100 bases:

>100_bases
TCGCGCCCGGCAGCTTGGCGCAATACTGGAATTCGTGTCGCATCCCGAAGGCGGAGTGGAAGTGCGGCTCGAAATGCGAA
TGATGTAGGAGTTTTCCGGG

Downstream 100 bases:

>100_bases
CGGCATTGACAGGGCGTTTTAGGGGGCGGGGGACTTACCGGACTTTCGCCATATAAACTTGCATAAGGGTTTCCCTTAGT
AAAAAACCAGGGTTTCCCCA

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: Nitrogen regulation protein C [H]

Number of amino acids: Translated: 217; Mature: 216

Protein sequence:

>217_residues
MAASKAQVMLVDDHAMLRHGMAMLINLEPDMEVFAEAGDGDEALATLKAGHHADIVLMDVSLKTLSGFEVIKSIHTLLPA
LPVLVVSMHDEGVYAERALRAGARGYVMKQEPGEVLVTAIHEVLKGNIYLSKPMHAKLLNRVAGGNSEPEPLINSLTPSE
FEVLHLIGSGHSSQEIAKLLSRSIKTIETHRFNIRTKLNLKDGADLIRYATHWSEAQ

Sequences:

>Translated_217_residues
MAASKAQVMLVDDHAMLRHGMAMLINLEPDMEVFAEAGDGDEALATLKAGHHADIVLMDVSLKTLSGFEVIKSIHTLLPA
LPVLVVSMHDEGVYAERALRAGARGYVMKQEPGEVLVTAIHEVLKGNIYLSKPMHAKLLNRVAGGNSEPEPLINSLTPSE
FEVLHLIGSGHSSQEIAKLLSRSIKTIETHRFNIRTKLNLKDGADLIRYATHWSEAQ
>Mature_216_residues
AASKAQVMLVDDHAMLRHGMAMLINLEPDMEVFAEAGDGDEALATLKAGHHADIVLMDVSLKTLSGFEVIKSIHTLLPAL
PVLVVSMHDEGVYAERALRAGARGYVMKQEPGEVLVTAIHEVLKGNIYLSKPMHAKLLNRVAGGNSEPEPLINSLTPSEF
EVLHLIGSGHSSQEIAKLLSRSIKTIETHRFNIRTKLNLKDGADLIRYATHWSEAQ

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. Phosphorylated nreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nit

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790102, Length=201, Percent_Identity=35.8208955223881, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1788521, Length=201, Percent_Identity=35.3233830845771, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI1788222, Length=206, Percent_Identity=27.6699029126214, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1787473, Length=187, Percent_Identity=32.0855614973262, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1786747, Length=209, Percent_Identity=27.7511961722488, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788712, Length=205, Percent_Identity=27.8048780487805, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788546, Length=207, Percent_Identity=28.0193236714976, Blast_Score=64, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23714; Mature: 23583

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAASKAQVMLVDDHAMLRHGMAMLINLEPDMEVFAEAGDGDEALATLKAGHHADIVLMDV
CCCCCCEEEEECCHHHHHCCEEEEEECCCCHHHHEECCCCHHHHHHHHCCCCCCEEEEEE
SLKTLSGFEVIKSIHTLLPALPVLVVSMHDEGVYAERALRAGARGYVMKQEPGEVLVTAI
CHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHCCCCCEEEECCCCHHHHHHH
HEVLKGNIYLSKPMHAKLLNRVAGGNSEPEPLINSLTPSEFEVLHLIGSGHSSQEIAKLL
HHHHCCCEEEECCHHHHHHHHHHCCCCCCCHHHHCCCCCCEEEEEEECCCCCHHHHHHHH
SRSIKTIETHRFNIRTKLNLKDGADLIRYATHWSEAQ
HHHHHHHHHEEEEEEEEEECCCCHHHHHHHHHCCCCC
>Mature Secondary Structure 
AASKAQVMLVDDHAMLRHGMAMLINLEPDMEVFAEAGDGDEALATLKAGHHADIVLMDV
CCCCCEEEEECCHHHHHCCEEEEEECCCCHHHHEECCCCHHHHHHHHCCCCCCEEEEEE
SLKTLSGFEVIKSIHTLLPALPVLVVSMHDEGVYAERALRAGARGYVMKQEPGEVLVTAI
CHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHCCCCCEEEECCCCHHHHHHH
HEVLKGNIYLSKPMHAKLLNRVAGGNSEPEPLINSLTPSEFEVLHLIGSGHSSQEIAKLL
HHHHCCCEEEECCHHHHHHHHHHCCCCCCCHHHHCCCCCCEEEEEEECCCCCHHHHHHHH
SRSIKTIETHRFNIRTKLNLKDGADLIRYATHWSEAQ
HHHHHHHHHEEEEEEEEEECCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12426351 [H]