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The map label for this gene is narQ [H]

Identifier: 82701860

GI number: 82701860

Start: 847284

End: 848714

Strand: Direct

Name: narQ [H]

Synonym: Nmul_A0727

Alternate gene names: 82701860

Gene position: 847284-848714 (Clockwise)

Preceding gene: 82701858

Following gene: 82701861

Centisome position: 26.61

GC content: 53.04

Gene sequence:

>1431_bases
ATGATCAGCCGGGATAAAAGGCACTTCAACTCCGTCCATTCCCCTGTGGATGAACATGCTGACGCAAGTCAGGCGCTTCG
CGAGCGCCTGAAAGAAATCACCTGTCTCTATGAAATTCGCCGGGGCATGGGGCCGGAATTATCGGTGGAGAACGTTTGCC
GGCAGATTTTCGAGCACTTGATACACGCGATGCAATTTCCGGAAATTGCTACCGCCATGATCGAGCTCGACGGCAGACGC
TTCATTTCCCAGAATCACGACGAAGGTGCCACGCATGAGCTGCAATCGACGATTAACGTCAACGCCCATCCTTGTGGCCA
GCTACGGGTCTTCTATCCGGAAGATAAACCTTTCCTGGTGCCGGAAGAACAGCGGCTCATCGACGCGATCGCAACTGATC
TGGGAAGGTGGTTTGAGCGCAAACAGATCGACGAGGCGTTGCGCGAGCGTCTGAAAGAAATCACTTGCCTCTACGAGATT
CGCCATGGCATGGGAGTGGAATTATCGGTGGACAACGTCTGCCAGCAGATTTTCGAGCACCTGATACCCGCGATGCAATT
TCCGGAAATTGCTACCGCCATGATCGAACTCGATGGCAAGCGCTTCACTTCCAAGAACCACGGTCAGGGTCTTACGCACG
AACTGAAATCGACGATCAGCGCCAACAACCATTCCTGCGGCCAGTTGCGTGTCTTCTATCCCGAAGACAAACCTTTCCTG
GTGCCGGAAGAACAGCGGCTCATCGACGCGGTTGCGACTGATCTGGGGAGATGGTTTGAGCGCAAACATCTCGAGCAAAC
CCTGGTTTCCATAGCGGAAGAACATCAGCGTTCGATCGGCCAGGATTTACACGACAATCTCGGGCAGCAGATTGCAGCGA
TTGGCTATCAGGCCAAAGCGCTGCAGAAAAAAATATCCTCGTTGGGGAGTACGGATGCCGCAACCGTCGCTGCTTCCATC
GCGACTCAAGCACAGATCGCCGTGATGCAATGCAAGCAGCTTGCGCAGGGGCTGCTCCCATTTGAACTGGAGACCCATGG
CCTGGTGGCCGCACTGCGGGCATTTGCATCCAGAATCGCAATCACTTACAAGATTACTTGTGATTTTATATGCAAAAATG
AAGTTCTCATCAAGGATAAGGATCTTGCGCTTAATATTTACCGGATTGCCCAAGAGGCCACCAATAACGCAATACGCCAC
GGGAGCGCACAGCATGTGACAATTTCGCTGGATTCCGAGGAAGAAATGCTCTCTCTGTCGATACGCGATGATGGCGGCGG
CTTTGCCGGTTTTAACACAAAAGAGGGAGCGACTCCAGGAATGGGTATTAAAATCATGCAATATCGCGCCCGGCAGCTTG
GCGCAATACTGGAATTCGTGTCGCATCCCGAAGGCGGAGTGGAAGTGCGGCTCGAAATGCGAATGATGTAG

Upstream 100 bases:

>100_bases
ACGAAGGGTATGACTGATATAAACTAGGCAAAGTATTCAAATTCATGGCATGGAACGGCCGAGGTGAGAGACTGAAGTGA
TCGAACTATGAAAGCCTTCA

Downstream 100 bases:

>100_bases
GAGTTTTCCGGGATGGCAGCTTCGAAAGCACAGGTAATGCTGGTGGACGATCATGCCATGTTGCGGCACGGCATGGCAAT
GCTTATCAATCTTGAGCCAG

Product: putative signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 476; Mature: 476

Protein sequence:

>476_residues
MISRDKRHFNSVHSPVDEHADASQALRERLKEITCLYEIRRGMGPELSVENVCRQIFEHLIHAMQFPEIATAMIELDGRR
FISQNHDEGATHELQSTINVNAHPCGQLRVFYPEDKPFLVPEEQRLIDAIATDLGRWFERKQIDEALRERLKEITCLYEI
RHGMGVELSVDNVCQQIFEHLIPAMQFPEIATAMIELDGKRFTSKNHGQGLTHELKSTISANNHSCGQLRVFYPEDKPFL
VPEEQRLIDAVATDLGRWFERKHLEQTLVSIAEEHQRSIGQDLHDNLGQQIAAIGYQAKALQKKISSLGSTDAATVAASI
ATQAQIAVMQCKQLAQGLLPFELETHGLVAALRAFASRIAITYKITCDFICKNEVLIKDKDLALNIYRIAQEATNNAIRH
GSAQHVTISLDSEEEMLSLSIRDDGGGFAGFNTKEGATPGMGIKIMQYRARQLGAILEFVSHPEGGVEVRLEMRMM

Sequences:

>Translated_476_residues
MISRDKRHFNSVHSPVDEHADASQALRERLKEITCLYEIRRGMGPELSVENVCRQIFEHLIHAMQFPEIATAMIELDGRR
FISQNHDEGATHELQSTINVNAHPCGQLRVFYPEDKPFLVPEEQRLIDAIATDLGRWFERKQIDEALRERLKEITCLYEI
RHGMGVELSVDNVCQQIFEHLIPAMQFPEIATAMIELDGKRFTSKNHGQGLTHELKSTISANNHSCGQLRVFYPEDKPFL
VPEEQRLIDAVATDLGRWFERKHLEQTLVSIAEEHQRSIGQDLHDNLGQQIAAIGYQAKALQKKISSLGSTDAATVAASI
ATQAQIAVMQCKQLAQGLLPFELETHGLVAALRAFASRIAITYKITCDFICKNEVLIKDKDLALNIYRIAQEATNNAIRH
GSAQHVTISLDSEEEMLSLSIRDDGGGFAGFNTKEGATPGMGIKIMQYRARQLGAILEFVSHPEGGVEVRLEMRMM
>Mature_476_residues
MISRDKRHFNSVHSPVDEHADASQALRERLKEITCLYEIRRGMGPELSVENVCRQIFEHLIHAMQFPEIATAMIELDGRR
FISQNHDEGATHELQSTINVNAHPCGQLRVFYPEDKPFLVPEEQRLIDAIATDLGRWFERKQIDEALRERLKEITCLYEI
RHGMGVELSVDNVCQQIFEHLIPAMQFPEIATAMIELDGKRFTSKNHGQGLTHELKSTISANNHSCGQLRVFYPEDKPFL
VPEEQRLIDAVATDLGRWFERKHLEQTLVSIAEEHQRSIGQDLHDNLGQQIAAIGYQAKALQKKISSLGSTDAATVAASI
ATQAQIAVMQCKQLAQGLLPFELETHGLVAALRAFASRIAITYKITCDFICKNEVLIKDKDLALNIYRIAQEATNNAIRH
GSAQHVTISLDSEEEMLSLSIRDDGGGFAGFNTKEGATPGMGIKIMQYRARQLGAILEFVSHPEGGVEVRLEMRMM

Specific function: Acts as a sensor for nitrate/nitrite and transduces signal of nitrate/nitrite availability to the narL/narP proteins. NarQ probably activates narL and narP by phosphorylation. NarQ probably negatively regulates the narL protein by dephosphorylation [H]

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788812, Length=235, Percent_Identity=29.3617021276596, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87082311, Length=212, Percent_Identity=26.4150943396226, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR016380
- InterPro:   IPR011712
- InterPro:   IPR005467 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 53544; Mature: 53544

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISRDKRHFNSVHSPVDEHADASQALRERLKEITCLYEIRRGMGPELSVENVCRQIFEHL
CCCCCHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
IHAMQFPEIATAMIELDGRRFISQNHDEGATHELQSTINVNAHPCGQLRVFYPEDKPFLV
HHHHCCHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHCCCCCCCCCEEEECCCCCCCCC
PEEQRLIDAIATDLGRWFERKQIDEALRERLKEITCLYEIRHGMGVELSVDNVCQQIFEH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHH
LIPAMQFPEIATAMIELDGKRFTSKNHGQGLTHELKSTISANNHSCGQLRVFYPEDKPFL
HHHHCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCC
VPEEQRLIDAVATDLGRWFERKHLEQTLVSIAEEHQRSIGQDLHDNLGQQIAAIGYQAKA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQKKISSLGSTDAATVAASIATQAQIAVMQCKQLAQGLLPFELETHGLVAALRAFASRIA
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECHHHHHHHHHHHHHHEE
ITYKITCDFICKNEVLIKDKDLALNIYRIAQEATNNAIRHGSAQHVTISLDSEEEMLSLS
EEEEEEEEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEE
IRDDGGGFAGFNTKEGATPGMGIKIMQYRARQLGAILEFVSHPEGGVEVRLEMRMM
EECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECC
>Mature Secondary Structure
MISRDKRHFNSVHSPVDEHADASQALRERLKEITCLYEIRRGMGPELSVENVCRQIFEHL
CCCCCHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
IHAMQFPEIATAMIELDGRRFISQNHDEGATHELQSTINVNAHPCGQLRVFYPEDKPFLV
HHHHCCHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHCCCCCCCCCEEEECCCCCCCCC
PEEQRLIDAIATDLGRWFERKQIDEALRERLKEITCLYEIRHGMGVELSVDNVCQQIFEH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHH
LIPAMQFPEIATAMIELDGKRFTSKNHGQGLTHELKSTISANNHSCGQLRVFYPEDKPFL
HHHHCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCC
VPEEQRLIDAVATDLGRWFERKHLEQTLVSIAEEHQRSIGQDLHDNLGQQIAAIGYQAKA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQKKISSLGSTDAATVAASIATQAQIAVMQCKQLAQGLLPFELETHGLVAALRAFASRIA
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECHHHHHHHHHHHHHHEE
ITYKITCDFICKNEVLIKDKDLALNIYRIAQEATNNAIRHGSAQHVTISLDSEEEMLSLS
EEEEEEEEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEE
IRDDGGGFAGFNTKEGATPGMGIKIMQYRARQLGAILEFVSHPEGGVEVRLEMRMM
EECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1528845; 1508040; 9205837; 9278503 [H]