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The map label for this gene is mtgA

Identifier: 82701673

GI number: 82701673

Start: 621497

End: 622189

Strand: Direct

Name: mtgA

Synonym: Nmul_A0539

Alternate gene names: 82701673

Gene position: 621497-622189 (Clockwise)

Preceding gene: 82701672

Following gene: 82701674

Centisome position: 19.52

GC content: 50.51

Gene sequence:

>693_bases
ATGTTTTTCAAGCGCTGGTTCTGGCGGATATTCCTGTTTTTCATTGCCGTCATATTTGTCTATCAATTCTGGATTTTCAG
TCAGATTGTCTACTGGAACTATTTCAATCCTTCTTCCAGCGCTTTCATGCAAACCCGGCTGGAAACACTGCGGGAAAAAA
ATACGAAGGCTGCACTGCGTACCCGCTGGATTCCTTACGAACAGATTTCTCCGCATCTCAAGCGGGCAATCATTGCAGCC
GAGGATGCGAAATTTCTGGAGCATGAAGGATTCGATTTCGACGCTATCCAGAAGGCGTACGAGAAAAACCTGAAAAAAGG
CAGGCTGATCATGGGCGGCTCCACCATCAGCCAGCAACTGGCAAAAAACCTGTTTCTTTCCGGTGACAAGACCCCATGGC
GTAAACTCCAGGAAGCATTCATCACGCTGATGCTCGAGAAGGTGATGTCCAAACGCCGTATCCTGGAGATTTATCTGAAT
GTGATCGAATGGGGCAATGTGGTGTTTGGAGCCGAGGCCGCGGCTCGTCATTATTATGGTATTTCCGCTTCTTCTGTTTC
AAGGGAGCAGGCGGCCCGGCTCGCTGCCATGGTTCCCAGTCCCCGGTTCTATGACGAAAATCGGAATACCCCCTGGCTGT
CGAAGAAAACGCGCATGATTCTGGGCCGCATGGCGTCGGCTTCCATTCCCTGA

Upstream 100 bases:

>100_bases
TCGGCAGTCCGTAGATTGATAGGCGGAGCAGCGATAGCGTCATCCGCTGGTGAGGGTGGCGCAACTGCGCGACCTGGAAA
CAACAGTGGGAATAATAAGA

Downstream 100 bases:

>100_bases
GATAAAATAGCAGAGGTCGAGGTGGCCGCTGCGCTCTGTCCTGTCAGCCCGGAGCCGCGTTGTGGGAGAAGTCTCCTCCC
CGTCGGCTGTCGGCTGCCGG

Product: monofunctional biosynthetic peptidoglycan transglycosylase

Products: NA

Alternate protein names: Monofunctional TGase

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MFFKRWFWRIFLFFIAVIFVYQFWIFSQIVYWNYFNPSSSAFMQTRLETLREKNTKAALRTRWIPYEQISPHLKRAIIAA
EDAKFLEHEGFDFDAIQKAYEKNLKKGRLIMGGSTISQQLAKNLFLSGDKTPWRKLQEAFITLMLEKVMSKRRILEIYLN
VIEWGNVVFGAEAAARHYYGISASSVSREQAARLAAMVPSPRFYDENRNTPWLSKKTRMILGRMASASIP

Sequences:

>Translated_230_residues
MFFKRWFWRIFLFFIAVIFVYQFWIFSQIVYWNYFNPSSSAFMQTRLETLREKNTKAALRTRWIPYEQISPHLKRAIIAA
EDAKFLEHEGFDFDAIQKAYEKNLKKGRLIMGGSTISQQLAKNLFLSGDKTPWRKLQEAFITLMLEKVMSKRRILEIYLN
VIEWGNVVFGAEAAARHYYGISASSVSREQAARLAAMVPSPRFYDENRNTPWLSKKTRMILGRMASASIP
>Mature_230_residues
MFFKRWFWRIFLFFIAVIFVYQFWIFSQIVYWNYFNPSSSAFMQTRLETLREKNTKAALRTRWIPYEQISPHLKRAIIAA
EDAKFLEHEGFDFDAIQKAYEKNLKKGRLIMGGSTISQQLAKNLFLSGDKTPWRKLQEAFITLMLEKVMSKRRILEIYLN
VIEWGNVVFGAEAAARHYYGISASSVSREQAARLAAMVPSPRFYDENRNTPWLSKKTRMILGRMASASIP

Specific function: Cell wall formation

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 51 family

Homologues:

Organism=Escherichia coli, GI1789601, Length=218, Percent_Identity=38.9908256880734, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI87082258, Length=165, Percent_Identity=35.7575757575758, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1786343, Length=151, Percent_Identity=37.0860927152318, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1788867, Length=162, Percent_Identity=33.3333333333333, Blast_Score=78, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTGA_NITMU (Q2YBM4)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_411239.1
- ProteinModelPortal:   Q2YBM4
- SMR:   Q2YBM4
- STRING:   Q2YBM4
- GeneID:   3784722
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A0539
- eggNOG:   COG0744
- HOGENOM:   HBG685698
- OMA:   RISIHLK
- PhylomeDB:   Q2YBM4
- ProtClustDB:   PRK00056
- BioCyc:   NMUL323848:NMUL_A0539-MONOMER
- HAMAP:   MF_00766
- InterPro:   IPR001264
- InterPro:   IPR011812
- TIGRFAMs:   TIGR02070

Pfam domain/function: PF00912 Transgly

EC number: 2.4.2.- [C]

Molecular weight: Translated: 27020; Mature: 27020

Theoretical pI: Translated: 10.66; Mature: 10.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x117a9334)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFKRWFWRIFLFFIAVIFVYQFWIFSQIVYWNYFNPSSSAFMQTRLETLREKNTKAALR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHH
TRWIPYEQISPHLKRAIIAAEDAKFLEHEGFDFDAIQKAYEKNLKKGRLIMGGSTISQQL
HHCCCHHHHCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCEEEECCHHHHHHH
AKNLFLSGDKTPWRKLQEAFITLMLEKVMSKRRILEIYLNVIEWGNVVFGAEAAARHYYG
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECHHHHHHHHCC
ISASSVSREQAARLAAMVPSPRFYDENRNTPWLSKKTRMILGRMASASIP
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCH
>Mature Secondary Structure
MFFKRWFWRIFLFFIAVIFVYQFWIFSQIVYWNYFNPSSSAFMQTRLETLREKNTKAALR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHH
TRWIPYEQISPHLKRAIIAAEDAKFLEHEGFDFDAIQKAYEKNLKKGRLIMGGSTISQQL
HHCCCHHHHCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCEEEECCHHHHHHH
AKNLFLSGDKTPWRKLQEAFITLMLEKVMSKRRILEIYLNVIEWGNVVFGAEAAARHYYG
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECHHHHHHHHCC
ISASSVSREQAARLAAMVPSPRFYDENRNTPWLSKKTRMILGRMASASIP
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA