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The map label for this gene is aroE [H]

Identifier: 82701672

GI number: 82701672

Start: 620577

End: 621410

Strand: Direct

Name: aroE [H]

Synonym: Nmul_A0538

Alternate gene names: 82701672

Gene position: 620577-621410 (Clockwise)

Preceding gene: 82701671

Following gene: 82701673

Centisome position: 19.49

GC content: 59.59

Gene sequence:

>834_bases
GTGGTCATGAGTGATCTTTATGCCGTCATCGGTAATCCTGTTGCTCATAGCAAGTCGCCCCTGATTCATGCCGGGTTTGC
ACGTCAAAGCGGACAGGATGTGCGTTATGAAGCGATACTTGCGCCATTGGATGGGTTCGTGGAAACGGTAGCTGCCTTCA
GGCAGCGTGGCGGCAAAGGGGCGAACGTAACCGTGCCATTCAAGCTGGAAGCCCACACGCTATCAAGCTGCCTCACGGAG
CGGGCAAAGGCCGCGGGCGCAGTGAACACGCTTGTATTCGGGGCAGATGACATCCTGGGAGATAACACGGATGGCGCGGG
GCTGGTGCGGGACGTGGCCGTCAATCTCGGTTATGCGCTCGATGACCGGCGCGTTTTGCTCATGGGCGCGGGTGGAGCAG
CCCGGGGGGTAATCAGGCCCTTGCTCGAGCATGAGCCTGCCGCGCTGGTGATTGCCAATCGCACCCCCCAAAAAGCGGAT
GATCTGCAGCGGTTGTTTGCATCCTCGGGGAACGTTCTTTCCGCAGCGTACGAGGATCTTCGCGGGCAGGAATTCGACCT
TGTCATCAATGCCACTTCCGCCAGCCTGCAGGGCGACCTGCCGCCTCTGCCAAAAGGTATTTTCGCCGGCGCTTCGTTGG
CCTACGATATGATGTACGGCAAGGGACTTACTTCTTTTCTGCAATTCGCGCAGCAGCAGGGGGCAGCGCGGCTGGCCGAT
GGAATCGGCATGCTGGTGGAACAGGCGGCCGAATCCTTCTTTCTCTGGCGCGGGATACGGCCGGAAACGGAACCGGTCAT
CGGAATGTTAAGGTCAAGCCTCGGCAGTCCGTAG

Upstream 100 bases:

>100_bases
GTACCGGTTTGCGCGCAGGTATTGCTCGCAACGGCATGTCTCCCCGTTTCTTCCTCCCGGTCGCTCCAATCGGAGTCTGA
TTCCGTGATTTACATCATGA

Downstream 100 bases:

>100_bases
ATTGATAGGCGGAGCAGCGATAGCGTCATCCGCTGGTGAGGGTGGCGCAACTGCGCGACCTGGAAACAACAGTGGGAATA
ATAAGAATGTTTTTCAAGCG

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MVMSDLYAVIGNPVAHSKSPLIHAGFARQSGQDVRYEAILAPLDGFVETVAAFRQRGGKGANVTVPFKLEAHTLSSCLTE
RAKAAGAVNTLVFGADDILGDNTDGAGLVRDVAVNLGYALDDRRVLLMGAGGAARGVIRPLLEHEPAALVIANRTPQKAD
DLQRLFASSGNVLSAAYEDLRGQEFDLVINATSASLQGDLPPLPKGIFAGASLAYDMMYGKGLTSFLQFAQQQGAARLAD
GIGMLVEQAAESFFLWRGIRPETEPVIGMLRSSLGSP

Sequences:

>Translated_277_residues
MVMSDLYAVIGNPVAHSKSPLIHAGFARQSGQDVRYEAILAPLDGFVETVAAFRQRGGKGANVTVPFKLEAHTLSSCLTE
RAKAAGAVNTLVFGADDILGDNTDGAGLVRDVAVNLGYALDDRRVLLMGAGGAARGVIRPLLEHEPAALVIANRTPQKAD
DLQRLFASSGNVLSAAYEDLRGQEFDLVINATSASLQGDLPPLPKGIFAGASLAYDMMYGKGLTSFLQFAQQQGAARLAD
GIGMLVEQAAESFFLWRGIRPETEPVIGMLRSSLGSP
>Mature_277_residues
MVMSDLYAVIGNPVAHSKSPLIHAGFARQSGQDVRYEAILAPLDGFVETVAAFRQRGGKGANVTVPFKLEAHTLSSCLTE
RAKAAGAVNTLVFGADDILGDNTDGAGLVRDVAVNLGYALDDRRVLLMGAGGAARGVIRPLLEHEPAALVIANRTPQKAD
DLQRLFASSGNVLSAAYEDLRGQEFDLVINATSASLQGDLPPLPKGIFAGASLAYDMMYGKGLTSFLQFAQQQGAARLAD
GIGMLVEQAAESFFLWRGIRPETEPVIGMLRSSLGSP

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789675, Length=273, Percent_Identity=49.8168498168498, Blast_Score=261, Evalue=3e-71,
Organism=Escherichia coli, GI1787983, Length=279, Percent_Identity=29.3906810035842, Blast_Score=85, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6320332, Length=276, Percent_Identity=27.536231884058, Blast_Score=79, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 29228; Mature: 29228

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVMSDLYAVIGNPVAHSKSPLIHAGFARQSGQDVRYEAILAPLDGFVETVAAFRQRGGKG
CCHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
ANVTVPFKLEAHTLSSCLTERAKAAGAVNTLVFGADDILGDNTDGAGLVRDVAVNLGYAL
CEEEEEEEECHHHHHHHHHHHHHHHCHHHHEEECCHHHCCCCCCCCHHHHHHHHHCCEEE
DDRRVLLMGAGGAARGVIRPLLEHEPAALVIANRTPQKADDLQRLFASSGNVLSAAYEDL
CCCEEEEEECCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHH
RGQEFDLVINATSASLQGDLPPLPKGIFAGASLAYDMMYGKGLTSFLQFAQQQGAARLAD
CCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHH
GIGMLVEQAAESFFLWRGIRPETEPVIGMLRSSLGSP
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVMSDLYAVIGNPVAHSKSPLIHAGFARQSGQDVRYEAILAPLDGFVETVAAFRQRGGKG
CCHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
ANVTVPFKLEAHTLSSCLTERAKAAGAVNTLVFGADDILGDNTDGAGLVRDVAVNLGYAL
CEEEEEEEECHHHHHHHHHHHHHHHCHHHHEEECCHHHCCCCCCCCHHHHHHHHHCCEEE
DDRRVLLMGAGGAARGVIRPLLEHEPAALVIANRTPQKADDLQRLFASSGNVLSAAYEDL
CCCEEEEEECCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHH
RGQEFDLVINATSASLQGDLPPLPKGIFAGASLAYDMMYGKGLTSFLQFAQQQGAARLAD
CCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHH
GIGMLVEQAAESFFLWRGIRPETEPVIGMLRSSLGSP
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA