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The map label for this gene is melC2 [H]

Identifier: 82701661

GI number: 82701661

Start: 602454

End: 603491

Strand: Reverse

Name: melC2 [H]

Synonym: Nmul_A0527

Alternate gene names: 82701661

Gene position: 603491-602454 (Counterclockwise)

Preceding gene: 82701666

Following gene: 82701660

Centisome position: 18.95

GC content: 54.14

Gene sequence:

>1038_bases
ATGTACTATAGTTATTGTGTGCAAGGCGTATTGGCATCGAGCGAGAGTCATATTGCGCCGGTTGTTTTCCTTGAACCCTT
TGTCAGGAGCAAAAAAATGGACCATTCGCATAAGACCGGCGCGCACCTCCACCCTAAAACCTTCGATGAAGTTATCGCTC
TCGGCTTTCCCCTGGACAAGCTGGAGTTGCTTAAGGATATCCATAAGAAACTGGTAAAACCCCTGCTGGGCGGAGCAGCC
GCCTTTGCGCCCAAACCGCCGGGCGCACCGGTCACCCGCCAGAATCAGGCGGACCTTTCGCCCGAAAAACGGGAAGCATT
CCGCAATGCGGTTGTTCGTCTGGTGGAGGAAGGCAAATACCTCGAACTGGTCCAGTTTCATAGGGATATGTCGCACGACA
TGCATGGCATGATGGGCGAGACAGGCCTTTATCGTTTTCTGGGCTGGCATCGCCGTTATCTCGTCGAGTTCGAGCGGGAA
TTGCAGCGTGTTGACGCTGTTCTCCGTCCCGGTGCAACTGAAAAACTCGCGGTCCCTTATTGGCGCTGGGAAGATCCCTT
CCCCGCCTGGCTGAACGGTTTTCTGCCTGCAAACGATCCGGATACGGGAACACCCCCACCCTCACGCAAAAATGCTTCAC
CACCGCAAAAAGCCAACGCGACGGATGTGGATATCATCGTTAACCAGTTCTCCATCCAGAATACCGGTCTGAACAATGAA
AATGACTATACGAAATTCACTTACGGGCTCGAGGGCTGGGGCCGGAGACCGGATGGAACGAGCCTTCCCGGCCATAATCA
CGGTCATGCCTGGGTGGGTGGCATCATGAACAATACGATGTCATCACCCACGGATCCGGTTTTCTGGCTCCATCATGCCG
AAGTGGATCGTTTGTGGCATATCTGGCAACAGGCCAACTCATCGGCGGAACCTAACCTGAGCGGGTCTGACCGCATCATG
GACCCATGGGGGGAATCATACGATGACCTGGTGGATACGGAAGACCTGGGTTACGTCTACGACTCGACTTCGTTATAA

Upstream 100 bases:

>100_bases
TTGAAGCGAAATGCCTTTGGGCACAGAGCTCTCGATCGAGCTCAAGCTCAAGCGCAGACAGATATAGTCGGACTGTGTAA
AATCGAGCGGATCAATCGCC

Downstream 100 bases:

>100_bases
AAAGAGGTTGCATTTTCATTGCCGCGATGCTTTTTTCGGCACCCGCAAAAACCAATAATATTCGATTTCTCCCTGGAGGC
CGCCACATGAAGTCCAAAAG

Product: tyrosinase

Products: NA

Alternate protein names: Monophenol monooxygenase [H]

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MYYSYCVQGVLASSESHIAPVVFLEPFVRSKKMDHSHKTGAHLHPKTFDEVIALGFPLDKLELLKDIHKKLVKPLLGGAA
AFAPKPPGAPVTRQNQADLSPEKREAFRNAVVRLVEEGKYLELVQFHRDMSHDMHGMMGETGLYRFLGWHRRYLVEFERE
LQRVDAVLRPGATEKLAVPYWRWEDPFPAWLNGFLPANDPDTGTPPPSRKNASPPQKANATDVDIIVNQFSIQNTGLNNE
NDYTKFTYGLEGWGRRPDGTSLPGHNHGHAWVGGIMNNTMSSPTDPVFWLHHAEVDRLWHIWQQANSSAEPNLSGSDRIM
DPWGESYDDLVDTEDLGYVYDSTSL

Sequences:

>Translated_345_residues
MYYSYCVQGVLASSESHIAPVVFLEPFVRSKKMDHSHKTGAHLHPKTFDEVIALGFPLDKLELLKDIHKKLVKPLLGGAA
AFAPKPPGAPVTRQNQADLSPEKREAFRNAVVRLVEEGKYLELVQFHRDMSHDMHGMMGETGLYRFLGWHRRYLVEFERE
LQRVDAVLRPGATEKLAVPYWRWEDPFPAWLNGFLPANDPDTGTPPPSRKNASPPQKANATDVDIIVNQFSIQNTGLNNE
NDYTKFTYGLEGWGRRPDGTSLPGHNHGHAWVGGIMNNTMSSPTDPVFWLHHAEVDRLWHIWQQANSSAEPNLSGSDRIM
DPWGESYDDLVDTEDLGYVYDSTSL
>Mature_345_residues
MYYSYCVQGVLASSESHIAPVVFLEPFVRSKKMDHSHKTGAHLHPKTFDEVIALGFPLDKLELLKDIHKKLVKPLLGGAA
AFAPKPPGAPVTRQNQADLSPEKREAFRNAVVRLVEEGKYLELVQFHRDMSHDMHGMMGETGLYRFLGWHRRYLVEFERE
LQRVDAVLRPGATEKLAVPYWRWEDPFPAWLNGFLPANDPDTGTPPPSRKNASPPQKANATDVDIIVNQFSIQNTGLNNE
NDYTKFTYGLEGWGRRPDGTSLPGHNHGHAWVGGIMNNTMSSPTDPVFWLHHAEVDRLWHIWQQANSSAEPNLSGSDRIM
DPWGESYDDLVDTEDLGYVYDSTSL

Specific function: This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tyrosinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008922
- InterPro:   IPR002227 [H]

Pfam domain/function: PF00264 Tyrosinase [H]

EC number: =1.14.18.1 [H]

Molecular weight: Translated: 38997; Mature: 38997

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS00498 TYROSINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYYSYCVQGVLASSESHIAPVVFLEPFVRSKKMDHSHKTGAHLHPKTFDEVIALGFPLDK
CCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCHHH
LELLKDIHKKLVKPLLGGAAAFAPKPPGAPVTRQNQADLSPEKREAFRNAVVRLVEEGKY
HHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCH
LELVQFHRDMSHDMHGMMGETGLYRFLGWHRRYLVEFERELQRVDAVLRPGATEKLAVPY
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCE
WRWEDPFPAWLNGFLPANDPDTGTPPPSRKNASPPQKANATDVDIIVNQFSIQNTGLNNE
ECCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEHHEECCCCCCCC
NDYTKFTYGLEGWGRRPDGTSLPGHNHGHAWVGGIMNNTMSSPTDPVFWLHHAEVDRLWH
CCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHH
IWQQANSSAEPNLSGSDRIMDPWGESYDDLVDTEDLGYVYDSTSL
HHHHHCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCEEECCCCC
>Mature Secondary Structure
MYYSYCVQGVLASSESHIAPVVFLEPFVRSKKMDHSHKTGAHLHPKTFDEVIALGFPLDK
CCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCHHH
LELLKDIHKKLVKPLLGGAAAFAPKPPGAPVTRQNQADLSPEKREAFRNAVVRLVEEGKY
HHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCH
LELVQFHRDMSHDMHGMMGETGLYRFLGWHRRYLVEFERELQRVDAVLRPGATEKLAVPY
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCE
WRWEDPFPAWLNGFLPANDPDTGTPPPSRKNASPPQKANATDVDIIVNQFSIQNTGLNNE
ECCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEHHEECCCCCCCC
NDYTKFTYGLEGWGRRPDGTSLPGHNHGHAWVGGIMNNTMSSPTDPVFWLHHAEVDRLWH
CCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHH
IWQQANSSAEPNLSGSDRIMDPWGESYDDLVDTEDLGYVYDSTSL
HHHHHCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3002431; 2846043; 1901488 [H]