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The map label for this gene is surA

Identifier: 82701654

GI number: 82701654

Start: 590375

End: 591697

Strand: Reverse

Name: surA

Synonym: Nmul_A0520

Alternate gene names: 82701654

Gene position: 591697-590375 (Counterclockwise)

Preceding gene: 82701655

Following gene: 82701653

Centisome position: 18.58

GC content: 56.08

Gene sequence:

>1323_bases
ATGGGCACGAAATTGTCGTCGCGTTCCCCCTTTTCCCTTCCCTTTTTAACGCTGCTTGCCGGAATGGCCATTGCCCAGCA
ACCGGCGCATTCGGGGGTGGAAACCATCGACCATATCGTTGCGGTCGTGAATGAGAATGTGATCACCCGGCATGAACTGG
ATGAAATGCTCGGCGCCATGCTGAAACAATTGCAAAAGCAAGGCGTACAGCCTCCCCCGCCAGCCGTGCTGGAAAAACAG
CTTCTGGAGCGAATAATCCTGAACCGCGTGCAACTGCAACTTGCGAATGAAACCGGACTGACCGTGAGCGACGCGGAACT
CGACCAGACTTTGCGTCGTATCGCGCAGGAAAACAAGATGTCCCTGCAGGAGTTCGACAGGGCGCTGGCGGAAGACGGGG
TCAGCTTCAGCAAGTTCCGTGACGAGATTCGCGATGAAATCATCCTGGTCAGACTGAAAGAGCGTGAGGTAAGCAACCGC
GTCAGCGTGACCGAAGGGGAAGTCGATCATTTTCTGGAAACGCAGGAAGATTCGCCCAGCCAGAGCGACGAATATCGCAT
TGCTCATATTCTGATACAGGTCTCCGAAGGAGCCGACCCTTTGAAACGCGATGCGGCACGGCAACGGGCAGAAAGCGCCT
TGGCAAAATTGAAGGCAGGAACCGAATTTGCCCAGGTAGCCGCGGAATTCTCGGATGCGCCTGATGCGATGGAAGGCGGC
CTGCTCAATTGGCGTCCTGCTGCCCAGCTCACAAAAAAGTTTGCCGAAATACTGACCCCAATGAAACCGGGGGAAATCAC
CGGGATAATTCCGAGCCCGAATGGATTTCATATCCTCAAACTGGTCGAACGCCGCAACCAGGATACGGTGACCACTATGA
TAGACCAGACACATGCACGCCATATTCTGATAAAAATCAGCGAGCTCACCTCGGAGGCCGATGCTCACCGCCGTGTAACC
GAATTGAAGGAACGCCTGGATAATGGCAGCAAGTTCGAGGAACTGGCGAAGCTTCATTCGGAAGACGCCAGCGCCCCCAC
CGGGGGTGATCTCGGCTGGATCTCGCCGGGCGATACGGTGCCGGAATTTGAACAGGCCATGAGCGCTCTCAAACCGGGAG
AAATCAGCAGTCCTGTCCAATCTCCCTTTGGATGGCATCTCATTCAAGTCATCGAGCGCCGCACCCAGGACGTAAGTCAG
GAGCGCAAACGCCAGTCTGCACGCCAGGCGATCCGTGCCCGCAAAGCTGAGACGGCATTCCAGGAATGGTTGCAGCGCCT
GCGGGACCGGGCGTATGTCGAGTATCGGCTGGAAGAAGGCTAA

Upstream 100 bases:

>100_bases
CAGGGAAGCGGCTTGATAGAAGGGCCATAGCACCTCGCATCTATCACTGTTCGCACGTCACGATCACGCTATCTCTCCCC
TATTCCAGAAGCTTATTCAC

Downstream 100 bases:

>100_bases
GGGTCTGTTAACATTTGTAAGAGACGGGGGCCGAAGTTGAATAATCCCAAGCTCGCGCTCACCGCAGGGGAACCCGCCGG
CATCGGTCCCGACCTGTGCG

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase surA; PPIase surA; Rotamase surA

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MGTKLSSRSPFSLPFLTLLAGMAIAQQPAHSGVETIDHIVAVVNENVITRHELDEMLGAMLKQLQKQGVQPPPPAVLEKQ
LLERIILNRVQLQLANETGLTVSDAELDQTLRRIAQENKMSLQEFDRALAEDGVSFSKFRDEIRDEIILVRLKEREVSNR
VSVTEGEVDHFLETQEDSPSQSDEYRIAHILIQVSEGADPLKRDAARQRAESALAKLKAGTEFAQVAAEFSDAPDAMEGG
LLNWRPAAQLTKKFAEILTPMKPGEITGIIPSPNGFHILKLVERRNQDTVTTMIDQTHARHILIKISELTSEADAHRRVT
ELKERLDNGSKFEELAKLHSEDASAPTGGDLGWISPGDTVPEFEQAMSALKPGEISSPVQSPFGWHLIQVIERRTQDVSQ
ERKRQSARQAIRARKAETAFQEWLQRLRDRAYVEYRLEEG

Sequences:

>Translated_440_residues
MGTKLSSRSPFSLPFLTLLAGMAIAQQPAHSGVETIDHIVAVVNENVITRHELDEMLGAMLKQLQKQGVQPPPPAVLEKQ
LLERIILNRVQLQLANETGLTVSDAELDQTLRRIAQENKMSLQEFDRALAEDGVSFSKFRDEIRDEIILVRLKEREVSNR
VSVTEGEVDHFLETQEDSPSQSDEYRIAHILIQVSEGADPLKRDAARQRAESALAKLKAGTEFAQVAAEFSDAPDAMEGG
LLNWRPAAQLTKKFAEILTPMKPGEITGIIPSPNGFHILKLVERRNQDTVTTMIDQTHARHILIKISELTSEADAHRRVT
ELKERLDNGSKFEELAKLHSEDASAPTGGDLGWISPGDTVPEFEQAMSALKPGEISSPVQSPFGWHLIQVIERRTQDVSQ
ERKRQSARQAIRARKAETAFQEWLQRLRDRAYVEYRLEEG
>Mature_439_residues
GTKLSSRSPFSLPFLTLLAGMAIAQQPAHSGVETIDHIVAVVNENVITRHELDEMLGAMLKQLQKQGVQPPPPAVLEKQL
LERIILNRVQLQLANETGLTVSDAELDQTLRRIAQENKMSLQEFDRALAEDGVSFSKFRDEIRDEIILVRLKEREVSNRV
SVTEGEVDHFLETQEDSPSQSDEYRIAHILIQVSEGADPLKRDAARQRAESALAKLKAGTEFAQVAAEFSDAPDAMEGGL
LNWRPAAQLTKKFAEILTPMKPGEITGIIPSPNGFHILKLVERRNQDTVTTMIDQTHARHILIKISELTSEADAHRRVTE
LKERLDNGSKFEELAKLHSEDASAPTGGDLGWISPGDTVPEFEQAMSALKPGEISSPVQSPFGWHLIQVIERRTQDVSQE
RKRQSARQAIRARKAETAFQEWLQRLRDRAYVEYRLEEG

Specific function: Chaperone involved in the correct folding and assembly of outer membrane proteins. It recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasm. Note=Is capable of associating with the outer membrane (By similarity)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PpiC domains

Homologues:

Organism=Escherichia coli, GI1786238, Length=420, Percent_Identity=31.1904761904762, Blast_Score=219, Evalue=3e-58,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): SURA_NITMU (Q2YBP3)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_411220.1
- HSSP:   P24327
- ProteinModelPortal:   Q2YBP3
- SMR:   Q2YBP3
- STRING:   Q2YBP3
- GeneID:   3784509
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A0520
- eggNOG:   COG0760
- HOGENOM:   HBG391483
- OMA:   RHILIKT
- PhylomeDB:   Q2YBP3
- ProtClustDB:   CLSK585520
- BioCyc:   NMUL323848:NMUL_A0520-MONOMER
- HAMAP:   MF_01183
- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR023034
- InterPro:   IPR015391
- InterPro:   IPR008880
- Gene3D:   G3DSA:1.10.3120.10

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N; SSF109998 Trigger_fac_C_bac

EC number: =5.2.1.8

Molecular weight: Translated: 49334; Mature: 49203

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: PS01096 PPIC_PPIASE_1; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTKLSSRSPFSLPFLTLLAGMAIAQQPAHSGVETIDHIVAVVNENVITRHELDEMLGAM
CCCCCCCCCCCCCHHHHHHHHHHHHHCHHHCHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
LKQLQKQGVQPPPPAVLEKQLLERIILNRVQLQLANETGLTVSDAELDQTLRRIAQENKM
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEECHHHHHHHHHHHHHHHCC
SLQEFDRALAEDGVSFSKFRDEIRDEIILVRLKEREVSNRVSVTEGEVDHFLETQEDSPS
CHHHHHHHHHHCCCCHHHHHHHHHHHEEEEEEHHHHHHCCCCCCCCHHHHHHHCCCCCCC
QSDEYRIAHILIQVSEGADPLKRDAARQRAESALAKLKAGTEFAQVAAEFSDAPDAMEGG
CCCCCEEHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHCC
LLNWRPAAQLTKKFAEILTPMKPGEITGIIPSPNGFHILKLVERRNQDTVTTMIDQTHAR
CCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHH
HILIKISELTSEADAHRRVTELKERLDNGSKFEELAKLHSEDASAPTGGDLGWISPGDTV
HHEEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
PEFEQAMSALKPGEISSPVQSPFGWHLIQVIERRTQDVSQERKRQSARQAIRARKAETAF
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QEWLQRLRDRAYVEYRLEEG
HHHHHHHHHHHEEHEEECCC
>Mature Secondary Structure 
GTKLSSRSPFSLPFLTLLAGMAIAQQPAHSGVETIDHIVAVVNENVITRHELDEMLGAM
CCCCCCCCCCCCHHHHHHHHHHHHHCHHHCHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
LKQLQKQGVQPPPPAVLEKQLLERIILNRVQLQLANETGLTVSDAELDQTLRRIAQENKM
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEECHHHHHHHHHHHHHHHCC
SLQEFDRALAEDGVSFSKFRDEIRDEIILVRLKEREVSNRVSVTEGEVDHFLETQEDSPS
CHHHHHHHHHHCCCCHHHHHHHHHHHEEEEEEHHHHHHCCCCCCCCHHHHHHHCCCCCCC
QSDEYRIAHILIQVSEGADPLKRDAARQRAESALAKLKAGTEFAQVAAEFSDAPDAMEGG
CCCCCEEHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHCC
LLNWRPAAQLTKKFAEILTPMKPGEITGIIPSPNGFHILKLVERRNQDTVTTMIDQTHAR
CCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHH
HILIKISELTSEADAHRRVTELKERLDNGSKFEELAKLHSEDASAPTGGDLGWISPGDTV
HHEEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
PEFEQAMSALKPGEISSPVQSPFGWHLIQVIERRTQDVSQERKRQSARQAIRARKAETAF
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QEWLQRLRDRAYVEYRLEEG
HHHHHHHHHHHEEHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA