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The map label for this gene is amtB [C]

Identifier: 82701650

GI number: 82701650

Start: 585829

End: 587052

Strand: Reverse

Name: amtB [C]

Synonym: Nmul_A0516

Alternate gene names: 82701650

Gene position: 587052-585829 (Counterclockwise)

Preceding gene: 82701651

Following gene: 82701642

Centisome position: 18.44

GC content: 55.07

Gene sequence:

>1224_bases
ATGAAAAAAAGTCTCTGCATGACGTTGTGTGGCACAGCCGGTTTTTTTCTGTTGTATTTAAGTGCCTGGGCGAGCGAGGG
GGGCACTGCGCCCCAGCTTAACGAGGCACGACAGGTAGCTCAATACAATTATGTAATCCATATCCTCGCCATGTTGCTGG
TGGGTTTCGGCTTTCTCATGGTATTTGTCAAAAGATATGGATTTGGAGCCACGACCGGAACATATCTGGTAGTCGCTGTC
GGTCTTCCGCTTTACATTCTGCTTCGCGCAAACGGCGTATTCGCCCACGAAATTGCTCCGAACACGGTGCAGGCACTGCT
CTTTGCTGAATTCGCGGTAGCGTCCGGGTTGATCGCCATGGGCGCGGTCCTCGGTCGTCTCCGCGTTTTCCAATACGCAC
TGCTGGCGCTGCTCCTGATTCCTGCTTATCTCTTGAACGAATGGCTGGTGCTGGATAATGGAATGGGTATGACCGAGGGA
TTTCAGGATACTGCGGGATCGATCATCATACATGCGTTCGGTGCATATTTTGGCTTGGGGTTATCCCTTGCGCTGACCAC
GGCGCGACAACGAAGCCAGCCGATTGAGTCGGATGCGACTTCTGATCGATTCGCAATGCTGGGTTCAATGGTCCTGTGGC
TTTTCTGGCCCAGTTTCGCCACCGCCATCGTTCCCTTCGAGCAGATGCCGCAGACAGTGGTCAACACTGTACTCGCTCTG
TGCGGCGCCACGATCACCACATATTTCTTGAGCACATATTTCCATAAAGGCAAAACCTCGATGGTCGATATGGCGAATGC
CGCGCTGGCCGGCGGAGTAGCGATCGGTTCCACCTGCAATATCGTGTCGCCGACAGGTGCTTTTGCGATCGGCCTGCTTG
CCGGCGCGGTCAGCGTCATCGGGTTCGTGTTCATTCAACCCGCACTTGAGAGACGCTTCAAGATCGTCGACACCTGTGGC
GTCCATAATCTGCACGGAATGCCGGGATTGCTGGGTGCATTCGTTGCTGTCCTGGTCGTGCCCGGCATAGCAGTTGCCCA
ATTCATCGGCATCGCCTTCAGTGTCGTGTTCGCTCTGATAGCAGGACTCGCGGCTGGCGCGCTCATCAGGGCCACCGGCA
CAACCCGTCTGGCTTACGAGGATAGTGAGGAATTCACCCACACCGAAGGACCGGAAGCTACGGAAATCGAGGCCATAGTG
CTGGAAGGCGAGACTTCAACTTAA

Upstream 100 bases:

>100_bases
TCCGTTTACTTTATTGAAATATCCCTATTGTACTTGAGGCTATCGAGGTTCACACTGTGCCTGGGCAAGTCAGATAACCG
TAAACAATATGGAGGGAAAA

Downstream 100 bases:

>100_bases
AAGGGCGGTGGCCTGAGCCAAAATCAAGGAGTCGGAGTCGACTGATTTCTGAAAGTCAATCGGCTCCGACCCCATTGATC
CTCTACTTCTTCGGCATATA

Product: Rh-like protein/ammonium transporter

Products: NH3 [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MKKSLCMTLCGTAGFFLLYLSAWASEGGTAPQLNEARQVAQYNYVIHILAMLLVGFGFLMVFVKRYGFGATTGTYLVVAV
GLPLYILLRANGVFAHEIAPNTVQALLFAEFAVASGLIAMGAVLGRLRVFQYALLALLLIPAYLLNEWLVLDNGMGMTEG
FQDTAGSIIIHAFGAYFGLGLSLALTTARQRSQPIESDATSDRFAMLGSMVLWLFWPSFATAIVPFEQMPQTVVNTVLAL
CGATITTYFLSTYFHKGKTSMVDMANAALAGGVAIGSTCNIVSPTGAFAIGLLAGAVSVIGFVFIQPALERRFKIVDTCG
VHNLHGMPGLLGAFVAVLVVPGIAVAQFIGIAFSVVFALIAGLAAGALIRATGTTRLAYEDSEEFTHTEGPEATEIEAIV
LEGETST

Sequences:

>Translated_407_residues
MKKSLCMTLCGTAGFFLLYLSAWASEGGTAPQLNEARQVAQYNYVIHILAMLLVGFGFLMVFVKRYGFGATTGTYLVVAV
GLPLYILLRANGVFAHEIAPNTVQALLFAEFAVASGLIAMGAVLGRLRVFQYALLALLLIPAYLLNEWLVLDNGMGMTEG
FQDTAGSIIIHAFGAYFGLGLSLALTTARQRSQPIESDATSDRFAMLGSMVLWLFWPSFATAIVPFEQMPQTVVNTVLAL
CGATITTYFLSTYFHKGKTSMVDMANAALAGGVAIGSTCNIVSPTGAFAIGLLAGAVSVIGFVFIQPALERRFKIVDTCG
VHNLHGMPGLLGAFVAVLVVPGIAVAQFIGIAFSVVFALIAGLAAGALIRATGTTRLAYEDSEEFTHTEGPEATEIEAIV
LEGETST
>Mature_407_residues
MKKSLCMTLCGTAGFFLLYLSAWASEGGTAPQLNEARQVAQYNYVIHILAMLLVGFGFLMVFVKRYGFGATTGTYLVVAV
GLPLYILLRANGVFAHEIAPNTVQALLFAEFAVASGLIAMGAVLGRLRVFQYALLALLLIPAYLLNEWLVLDNGMGMTEG
FQDTAGSIIIHAFGAYFGLGLSLALTTARQRSQPIESDATSDRFAMLGSMVLWLFWPSFATAIVPFEQMPQTVVNTVLAL
CGATITTYFLSTYFHKGKTSMVDMANAALAGGVAIGSTCNIVSPTGAFAIGLLAGAVSVIGFVFIQPALERRFKIVDTCG
VHNLHGMPGLLGAFVAVLVVPGIAVAQFIGIAFSVVFALIAGLAAGALIRATGTTRLAYEDSEEFTHTEGPEATEIEAIV
LEGETST

Specific function: Involved In The Uptake Of Ammonia (Probable). [C]

COG id: COG0004

COG function: function code P; Ammonia permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ammonium transporter (TC 2.A.49) family [H]

Homologues:

Organism=Homo sapiens, GI224548945, Length=330, Percent_Identity=41.5151515151515, Blast_Score=212, Evalue=4e-55,
Organism=Homo sapiens, GI156627565, Length=355, Percent_Identity=36.3380281690141, Blast_Score=198, Evalue=7e-51,
Organism=Homo sapiens, GI7706683, Length=313, Percent_Identity=36.741214057508, Blast_Score=182, Evalue=3e-46,
Organism=Homo sapiens, GI20336225, Length=317, Percent_Identity=29.3375394321767, Blast_Score=96, Evalue=9e-20,
Organism=Homo sapiens, GI301129227, Length=313, Percent_Identity=28.4345047923323, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI189095266, Length=278, Percent_Identity=31.294964028777, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI301129223, Length=277, Percent_Identity=29.6028880866426, Blast_Score=89, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17563228, Length=322, Percent_Identity=41.6149068322981, Blast_Score=219, Evalue=3e-57,
Organism=Caenorhabditis elegans, GI17563230, Length=325, Percent_Identity=36.6153846153846, Blast_Score=183, Evalue=1e-46,
Organism=Drosophila melanogaster, GI21355411, Length=420, Percent_Identity=32.1428571428571, Blast_Score=199, Evalue=4e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001905
- InterPro:   IPR018047 [H]

Pfam domain/function: PF00909 Ammonium_transp [H]

EC number: NA

Molecular weight: Translated: 43086; Mature: 43086

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKSLCMTLCGTAGFFLLYLSAWASEGGTAPQLNEARQVAQYNYVIHILAMLLVGFGFLM
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFVKRYGFGATTGTYLVVAVGLPLYILLRANGVFAHEIAPNTVQALLFAEFAVASGLIAM
HHHHHHCCCCCCHHHHHHHHHHHHEEEHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHH
GAVLGRLRVFQYALLALLLIPAYLLNEWLVLDNGMGMTEGFQDTAGSIIIHAFGAYFGLG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHH
LSLALTTARQRSQPIESDATSDRFAMLGSMVLWLFWPSFATAIVPFEQMPQTVVNTVLAL
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
CGATITTYFLSTYFHKGKTSMVDMANAALAGGVAIGSTCNIVSPTGAFAIGLLAGAVSVI
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEECCCCCCCCCCHHHHHHHHHHHHHHH
GFVFIQPALERRFKIVDTCGVHNLHGMPGLLGAFVAVLVVPGIAVAQFIGIAFSVVFALI
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGLAAGALIRATGTTRLAYEDSEEFTHTEGPEATEIEAIVLEGETST
HHHHHCHHEEECCCEEEEECCCCCCCCCCCCCCCCEEEEEEECCCCC
>Mature Secondary Structure
MKKSLCMTLCGTAGFFLLYLSAWASEGGTAPQLNEARQVAQYNYVIHILAMLLVGFGFLM
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFVKRYGFGATTGTYLVVAVGLPLYILLRANGVFAHEIAPNTVQALLFAEFAVASGLIAM
HHHHHHCCCCCCHHHHHHHHHHHHEEEHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHH
GAVLGRLRVFQYALLALLLIPAYLLNEWLVLDNGMGMTEGFQDTAGSIIIHAFGAYFGLG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHH
LSLALTTARQRSQPIESDATSDRFAMLGSMVLWLFWPSFATAIVPFEQMPQTVVNTVLAL
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
CGATITTYFLSTYFHKGKTSMVDMANAALAGGVAIGSTCNIVSPTGAFAIGLLAGAVSVI
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEECCCCCCCCCCHHHHHHHHHHHHHHH
GFVFIQPALERRFKIVDTCGVHNLHGMPGLLGAFVAVLVVPGIAVAQFIGIAFSVVFALI
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGLAAGALIRATGTTRLAYEDSEEFTHTEGPEATEIEAIVLEGETST
HHHHHCHHEEECCCEEEEECCCCCCCCCCCCCCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NH3 [Periplasm] [C]

Specific reaction: NH3 [Periplasm] = NH3 [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]