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The map label for this gene is fur [H]

Identifier: 82701609

GI number: 82701609

Start: 531400

End: 531849

Strand: Reverse

Name: fur [H]

Synonym: Nmul_A0475

Alternate gene names: 82701609

Gene position: 531849-531400 (Counterclockwise)

Preceding gene: 82701615

Following gene: 82701608

Centisome position: 16.7

GC content: 51.78

Gene sequence:

>450_bases
ATGAGTAATCCGAGCAATCTTAAGACCATGGGCTTGAAGGCTACGCTGCCGCGCCTTAGAATACTGAGTCTGTTCGAAAG
CAGTCCTGTCCGGCATCTCTCTGCGGAGGATGTTTACAGAACGCTCATCAGCGAAGGCGATGATATCGGTCTGGCCACGG
TCTACCGGGTACTGACCCAGTTTGAACAGGCCGGGTTGCTCGAGCGCCACCATTTTGAAGGCGGCAAGGCAGTGTTTGAG
CTTGCCAGCGACGCCCATCATGACCATCTGGTCTGCCTGCAATGCGGCAGGGTGGAAGAATTTTATGACGCCGAAATCGA
GAAGCGTCAGATTAAAATTGCCCGTGAACGCGGATTTGCCATACACGAGCACTCGCTTTCACTTTACGCGGATTGCATCA
AGCCCTCATGTCCATATCGAAAAGGGGATGAAAAGGATAGTAAAAGTTAA

Upstream 100 bases:

>100_bases
AGCCAACGTGATAATTCTTGCGCGCATCGCGGCGACGTAGGTTTCCAAAGCAAACTTAACGTTATATGATACAGCAAATA
ACTTGACGATTGGATGCACT

Downstream 100 bases:

>100_bases
GCTTTTCATCCCTTCATGGAGCGCAGAGTCAAGTATCGTGACATTTATGGCCCGGTACGGCGATTGTATGCGCATGTTCT
TCAGAAGCAGGGTCTTGAGA

Product: ferric uptake regulator family protein

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 149; Mature: 148

Protein sequence:

>149_residues
MSNPSNLKTMGLKATLPRLRILSLFESSPVRHLSAEDVYRTLISEGDDIGLATVYRVLTQFEQAGLLERHHFEGGKAVFE
LASDAHHDHLVCLQCGRVEEFYDAEIEKRQIKIARERGFAIHEHSLSLYADCIKPSCPYRKGDEKDSKS

Sequences:

>Translated_149_residues
MSNPSNLKTMGLKATLPRLRILSLFESSPVRHLSAEDVYRTLISEGDDIGLATVYRVLTQFEQAGLLERHHFEGGKAVFE
LASDAHHDHLVCLQCGRVEEFYDAEIEKRQIKIARERGFAIHEHSLSLYADCIKPSCPYRKGDEKDSKS
>Mature_148_residues
SNPSNLKTMGLKATLPRLRILSLFESSPVRHLSAEDVYRTLISEGDDIGLATVYRVLTQFEQAGLLERHHFEGGKAVFEL
ASDAHHDHLVCLQCGRVEEFYDAEIEKRQIKIARERGFAIHEHSLSLYADCIKPSCPYRKGDEKDSKS

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. Regulator for biosynthesis of the siderophore alcaligin E [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=135, Percent_Identity=54.8148148148148, Blast_Score=155, Evalue=8e-40,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 16886; Mature: 16755

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNPSNLKTMGLKATLPRLRILSLFESSPVRHLSAEDVYRTLISEGDDIGLATVYRVLTQ
CCCCCCCCHHCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHH
FEQAGLLERHHFEGGKAVFELASDAHHDHLVCLQCGRVEEFYDAEIEKRQIKIARERGFA
HHHCCHHHHHHCCCCHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCE
IHEHSLSLYADCIKPSCPYRKGDEKDSKS
EEHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SNPSNLKTMGLKATLPRLRILSLFESSPVRHLSAEDVYRTLISEGDDIGLATVYRVLTQ
CCCCCCCHHCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHH
FEQAGLLERHHFEGGKAVFELASDAHHDHLVCLQCGRVEEFYDAEIEKRQIKIARERGFA
HHHCCHHHHHHCCCCHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCE
IHEHSLSLYADCIKPSCPYRKGDEKDSKS
EEHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA