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The map label for this gene is rfbB [C]

Identifier: 82701561

GI number: 82701561

Start: 474046

End: 474975

Strand: Reverse

Name: rfbB [C]

Synonym: Nmul_A0427

Alternate gene names: 82701561

Gene position: 474975-474046 (Counterclockwise)

Preceding gene: 82701562

Following gene: 82701560

Centisome position: 14.92

GC content: 54.95

Gene sequence:

>930_bases
ATGTCCAGCGAGATTGCCATTGTCTATGGCGCCAGCGGTTTTCTGGGCAGTCACGTTGCCGACGCGCTCTCCGACTCGGG
CTATCGGGTGCGCCTGTTCGACCGCTCTCCATCGCGCTACCAGCGCGCGGATCAGGAGATGATCATTGGCGATATCATGG
ATCTTGAGCAGGTGAAGGAAGCGGCTCATGGTGCTGACGTGGTTTACAACTTTGCCGCCATTGCAGATATTGACGAAGCA
CAGGAAAAACCCATCGCTACGGCGACCATCAATGTGCTGGGTAACATGCATACACTGGAAGCAGCGCGTCTTGCCGGCGC
CCGGCGCTTTGTCTTCGCGAGCACGATTTACGTCTATTCCGAATCGGGTTCCTTTTACCGGGCCAGCAAGCAGGCAGCGG
AACGTTTCATCGAAACCTACCACGAGCGTTATGGCCTGGAGTATAGTATTTTGCGCTATGGCTCGCTCTATGGCCGACGC
GCCGACGCGAGAAACGGCATCTACCGCATGCTGTACGAGGCGCTGGAACAGCACTCGATTACTTATCACGGCAGTGGAGA
AGCAATTCGGGAATATATTCATGTGGAAGATGCGGCGCGCATGAGCGTACAAGTGCTGGCACCGGAGTTTGCGAATCGTC
ACCTGATCCTGACAGGGCAGGAGCGGTTGCACATCAAGGATGTAATGACAATGATTTCAGAAATTATGCCCTGGAAAGTC
GATCTGCGTTTCGACGAGGCCCGTGCGGGGCATCATTACGAAGTAACGCCTTATGCTTATCAGCCGCGGATCGGCCGCAA
GCTGGTTCTGAACGAGCATGTCGATCTGGGCCAGGGGCTGCTGGATTGCCTTCAGGATATTCATCAGAGCATGCACCATT
CGGGTGAAAATGAGGAGATCATACCGCTGGCGTCGGATAATAAGGCATGA

Upstream 100 bases:

>100_bases
TTGCAAAGGAATCGCGTCAGCGTATGGAACTGGAAGCCGCGGAAAATCTGGTGCGCGGATTGATCGAAGCCGGTGTAATG
GAAAAAGGTTAAAACAGCAG

Downstream 100 bases:

>100_bases
AGACTGCTGCATGGCAAGCGATCATTTTCGATTTCGACGGGGTCGTGGTCGAATCAGGAGAAATCAAGACACAGGCGTTT
GCCAACCTCTACCAGGAATA

Product: NAD-dependent epimerase/dehydratase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MSSEIAIVYGASGFLGSHVADALSDSGYRVRLFDRSPSRYQRADQEMIIGDIMDLEQVKEAAHGADVVYNFAAIADIDEA
QEKPIATATINVLGNMHTLEAARLAGARRFVFASTIYVYSESGSFYRASKQAAERFIETYHERYGLEYSILRYGSLYGRR
ADARNGIYRMLYEALEQHSITYHGSGEAIREYIHVEDAARMSVQVLAPEFANRHLILTGQERLHIKDVMTMISEIMPWKV
DLRFDEARAGHHYEVTPYAYQPRIGRKLVLNEHVDLGQGLLDCLQDIHQSMHHSGENEEIIPLASDNKA

Sequences:

>Translated_309_residues
MSSEIAIVYGASGFLGSHVADALSDSGYRVRLFDRSPSRYQRADQEMIIGDIMDLEQVKEAAHGADVVYNFAAIADIDEA
QEKPIATATINVLGNMHTLEAARLAGARRFVFASTIYVYSESGSFYRASKQAAERFIETYHERYGLEYSILRYGSLYGRR
ADARNGIYRMLYEALEQHSITYHGSGEAIREYIHVEDAARMSVQVLAPEFANRHLILTGQERLHIKDVMTMISEIMPWKV
DLRFDEARAGHHYEVTPYAYQPRIGRKLVLNEHVDLGQGLLDCLQDIHQSMHHSGENEEIIPLASDNKA
>Mature_308_residues
SSEIAIVYGASGFLGSHVADALSDSGYRVRLFDRSPSRYQRADQEMIIGDIMDLEQVKEAAHGADVVYNFAAIADIDEAQ
EKPIATATINVLGNMHTLEAARLAGARRFVFASTIYVYSESGSFYRASKQAAERFIETYHERYGLEYSILRYGSLYGRRA
DARNGIYRMLYEALEQHSITYHGSGEAIREYIHVEDAARMSVQVLAPEFANRHLILTGQERLHIKDVMTMISEIMPWKVD
LRFDEARAGHHYEVTPYAYQPRIGRKLVLNEHVDLGQGLLDCLQDIHQSMHHSGENEEIIPLASDNKA

Specific function: DTDP-L-RHAMNOSE BIOSYNTHESIS WITHIN THE O ANTIGEN BIOSYNTHESIS PATHWAY OF LIPOPOLYSACCHARIDE BIOSYNTHESIS. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI42516563, Length=231, Percent_Identity=25.5411255411255, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI7657641, Length=229, Percent_Identity=25.764192139738, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1788353, Length=279, Percent_Identity=25.8064516129032, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI48994969, Length=268, Percent_Identity=25.7462686567164, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 34935; Mature: 34804

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSEIAIVYGASGFLGSHVADALSDSGYRVRLFDRSPSRYQRADQEMIIGDIMDLEQVKE
CCCCEEEEEECCCHHHHHHHHHHCCCCCEEEEEECCCHHHHHCCHHHHHHHHHHHHHHHH
AAHGADVVYNFAAIADIDEAQEKPIATATINVLGNMHTLEAARLAGARRFVFASTIYVYS
HHCCHHHHHHHHHHHCCHHHHCCCCCEEEHHHHCCHHHHHHHHHHCCHHEEEEEEEEEEE
ESGSFYRASKQAAERFIETYHERYGLEYSILRYGSLYGRRADARNGIYRMLYEALEQHSI
CCCCEEHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCE
TYHGSGEAIREYIHVEDAARMSVQVLAPEFANRHLILTGQERLHIKDVMTMISEIMPWKV
EEECCHHHHHHHHHHHHHHHHEEEEECHHHCCCEEEEECCCHHHHHHHHHHHHHHCCEEE
DLRFDEARAGHHYEVTPYAYQPRIGRKLVLNEHVDLGQGLLDCLQDIHQSMHHSGENEEI
EEEECCCCCCCCEECCCCEECCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCEE
IPLASDNKA
EEECCCCCC
>Mature Secondary Structure 
SSEIAIVYGASGFLGSHVADALSDSGYRVRLFDRSPSRYQRADQEMIIGDIMDLEQVKE
CCCEEEEEECCCHHHHHHHHHHCCCCCEEEEEECCCHHHHHCCHHHHHHHHHHHHHHHH
AAHGADVVYNFAAIADIDEAQEKPIATATINVLGNMHTLEAARLAGARRFVFASTIYVYS
HHCCHHHHHHHHHHHCCHHHHCCCCCEEEHHHHCCHHHHHHHHHHCCHHEEEEEEEEEEE
ESGSFYRASKQAAERFIETYHERYGLEYSILRYGSLYGRRADARNGIYRMLYEALEQHSI
CCCCEEHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCE
TYHGSGEAIREYIHVEDAARMSVQVLAPEFANRHLILTGQERLHIKDVMTMISEIMPWKV
EEECCHHHHHHHHHHHHHHHHEEEEECHHHCCCEEEEECCCHHHHHHHHHHHHHHCCEEE
DLRFDEARAGHHYEVTPYAYQPRIGRKLVLNEHVDLGQGLLDCLQDIHQSMHHSGENEEI
EEEECCCCCCCCEECCCCEECCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCEE
IPLASDNKA
EEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]