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The map label for this gene is frzCD [H]

Identifier: 82701466

GI number: 82701466

Start: 359760

End: 361253

Strand: Direct

Name: frzCD [H]

Synonym: Nmul_A0332

Alternate gene names: 82701466

Gene position: 359760-361253 (Clockwise)

Preceding gene: 82701465

Following gene: 82701467

Centisome position: 11.3

GC content: 52.81

Gene sequence:

>1494_bases
ATGACCATCAGTGAAAAGATAATTGGAGGGTACGCCATCATACTGGCGCTTCTTGCACTCTCCACCGCTGTCGCATTCTA
TGCACTCGGCCAGACACAGGCGACCTACGATCATTTCCTGCGCGTAGACGAGCGACTGATGGAAAGTGCGAATGAACTTC
GGATTGCGGGATTTGCGCAACAAACCTATGTTCGGGGTATTTTGCTTTATCCAGACCTGCTGAAGACCAACCACGCACTC
CTCCAGGACAATGATCGCCGGTTCAAGCAAATCCTCGAAAAAATTCGACAGCTAAGGAGTGGAAACAAGGGGGATAGTCT
ACTCGACGAGCTCCAGTCCCTGCACCAACAACTGGAGGAGGCCCAGCAACAAGCCGTCCGGCTCTCGTTCGAGCAAAAAC
GCGAGGAAGCGCTCGCCTTCGTGACGAACACATTCCGCCCCCTCAGCCTTGTATTTATAGATAAGGCCAAGCATTTCTAT
GAGCAACAATCTGCAATTCTGGAAAGTAGAAAAATTGAAGCCTCGGATAAAGTAAGCTCCTATACCGCTGTATTGGTGGC
TGTTTCTTTATTTACTGTTTTGGTTGGACTAACAATCGGCATTCGCCTGAGTCGCATGATTACCGGGCGGCTCCGGGAGA
GCATCGCCCAACTTGCGTCGTCTTCAGCAGAGATTCTTTCCACCACGTCCCAGGTAGCCGCTGGCGCAGCCGAGACTGCA
GCCGCAGTAAGCGAGACAACCGCCACCGTGGAAGAGGTCAAGCAAACCGCATTGACTACGAGCCAGAAAGCCAAATATGT
GTCAGACAGCGCCCAGAAAGCTTCCAATATCTCCGAGGCTGGACGCAAATCGGTGGGGGAGGCTATTAGTGGAATGAATC
GGATTCAGGAGCAGATGGAATCCATAGCTGAGAGCATTATGCAGCTCTCCAAGCAGGGGCATGCCATCGGCGAGATCATT
GCCACAGTCAACGATCTGGCTGAGCAATCCAATTTATTGGCCGTGAATGCCGCTATTGAGGCGACGCGGGCTGGGGAGCA
AGGTAAGAGTTTTGGCGTAGTTGCTCGAGAGATAAGAAGTCTGGCGGATCAATCCAAACAAGCCACTGCCCAAGTGCGAA
CCATTCTGGGGGATATTCAGAAAGCGACTAATGCTGCGGTACTCGCCACTGAGCAGGGCAATAAAGCGGTAGAGGCGGGG
GTCAGGCAATCCACCGAAACGGATGAAGCAATCCGCCTGCTGTCCACCAGCATCAGTGAGGCAGCGCAAGCAGCTACCCA
AATCGCGGCATCAAGCAAGCAACAAATGGTCGGCATGGACCAGGTGGTGATGGCCATGACTAATATCCAGCAGGCGAGCG
AACAGAACGTGGCAGGTACCAAGCAGGCAGAATCAGCGGCACAAGGCTTGTATGAGATGGGGAATAAATTGAGTGTCCTC
GTAGGCAGCAAGAAAGACCGTTTCGTAGAGGAAGCGGGAAAAGTCCATGCCTGA

Upstream 100 bases:

>100_bases
TGGATGAAAGCATCGTTGTAGATGAGCAAGTAGTCGAGTAGAGAAGTATCGAAATGGGTGAAGACACTGAAATGACGAAA
CGAAGTTTTGAAAGGACAGC

Downstream 100 bases:

>100_bases
CAAAAGGGATGTGCTTTTGGAAAGGCTCCTTGCAATGTTTCGCATCGAGGCAGAGGCCCACCTGAAGGATATATCGTCGG
GACTGCTCGCCCTGGAGGGA

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 497; Mature: 496

Protein sequence:

>497_residues
MTISEKIIGGYAIILALLALSTAVAFYALGQTQATYDHFLRVDERLMESANELRIAGFAQQTYVRGILLYPDLLKTNHAL
LQDNDRRFKQILEKIRQLRSGNKGDSLLDELQSLHQQLEEAQQQAVRLSFEQKREEALAFVTNTFRPLSLVFIDKAKHFY
EQQSAILESRKIEASDKVSSYTAVLVAVSLFTVLVGLTIGIRLSRMITGRLRESIAQLASSSAEILSTTSQVAAGAAETA
AAVSETTATVEEVKQTALTTSQKAKYVSDSAQKASNISEAGRKSVGEAISGMNRIQEQMESIAESIMQLSKQGHAIGEII
ATVNDLAEQSNLLAVNAAIEATRAGEQGKSFGVVAREIRSLADQSKQATAQVRTILGDIQKATNAAVLATEQGNKAVEAG
VRQSTETDEAIRLLSTSISEAAQAATQIAASSKQQMVGMDQVVMAMTNIQQASEQNVAGTKQAESAAQGLYEMGNKLSVL
VGSKKDRFVEEAGKVHA

Sequences:

>Translated_497_residues
MTISEKIIGGYAIILALLALSTAVAFYALGQTQATYDHFLRVDERLMESANELRIAGFAQQTYVRGILLYPDLLKTNHAL
LQDNDRRFKQILEKIRQLRSGNKGDSLLDELQSLHQQLEEAQQQAVRLSFEQKREEALAFVTNTFRPLSLVFIDKAKHFY
EQQSAILESRKIEASDKVSSYTAVLVAVSLFTVLVGLTIGIRLSRMITGRLRESIAQLASSSAEILSTTSQVAAGAAETA
AAVSETTATVEEVKQTALTTSQKAKYVSDSAQKASNISEAGRKSVGEAISGMNRIQEQMESIAESIMQLSKQGHAIGEII
ATVNDLAEQSNLLAVNAAIEATRAGEQGKSFGVVAREIRSLADQSKQATAQVRTILGDIQKATNAAVLATEQGNKAVEAG
VRQSTETDEAIRLLSTSISEAAQAATQIAASSKQQMVGMDQVVMAMTNIQQASEQNVAGTKQAESAAQGLYEMGNKLSVL
VGSKKDRFVEEAGKVHA
>Mature_496_residues
TISEKIIGGYAIILALLALSTAVAFYALGQTQATYDHFLRVDERLMESANELRIAGFAQQTYVRGILLYPDLLKTNHALL
QDNDRRFKQILEKIRQLRSGNKGDSLLDELQSLHQQLEEAQQQAVRLSFEQKREEALAFVTNTFRPLSLVFIDKAKHFYE
QQSAILESRKIEASDKVSSYTAVLVAVSLFTVLVGLTIGIRLSRMITGRLRESIAQLASSSAEILSTTSQVAAGAAETAA
AVSETTATVEEVKQTALTTSQKAKYVSDSAQKASNISEAGRKSVGEAISGMNRIQEQMESIAESIMQLSKQGHAIGEIIA
TVNDLAEQSNLLAVNAAIEATRAGEQGKSFGVVAREIRSLADQSKQATAQVRTILGDIQKATNAAVLATEQGNKAVEAGV
RQSTETDEAIRLLSTSISEAAQAATQIAASSKQQMVGMDQVVMAMTNIQQASEQNVAGTKQAESAAQGLYEMGNKLSVLV
GSKKDRFVEEAGKVHA

Specific function: Methyl-accepting taxis protein necessary for the proper aggregation of cells to form fruiting bodies. Frz genes define a system of signal transduction analogous to the enterobacterial chemotaxis systems [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=241, Percent_Identity=31.1203319502075, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1787690, Length=274, Percent_Identity=29.5620437956204, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1788194, Length=264, Percent_Identity=32.1969696969697, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI2367378, Length=241, Percent_Identity=28.2157676348548, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI1789453, Length=215, Percent_Identity=31.1627906976744, Blast_Score=84, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004089 [H]

Pfam domain/function: PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 53587; Mature: 53456

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTISEKIIGGYAIILALLALSTAVAFYALGQTQATYDHFLRVDERLMESANELRIAGFAQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHH
QTYVRGILLYPDLLKTNHALLQDNDRRFKQILEKIRQLRSGNKGDSLLDELQSLHQQLEE
HHHHHHHHCCHHHHHCCCHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
AQQQAVRLSFEQKREEALAFVTNTFRPLSLVFIDKAKHFYEQQSAILESRKIEASDKVSS
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
YTAVLVAVSLFTVLVGLTIGIRLSRMITGRLRESIAQLASSSAEILSTTSQVAAGAAETA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCHHHHH
AAVSETTATVEEVKQTALTTSQKAKYVSDSAQKASNISEAGRKSVGEAISGMNRIQEQME
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIAESIMQLSKQGHAIGEIIATVNDLAEQSNLLAVNAAIEATRAGEQGKSFGVVAREIRS
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCEEEEHHHHHHHHCCCCCCHHHHHHHHHHH
LADQSKQATAQVRTILGDIQKATNAAVLATEQGNKAVEAGVRQSTETDEAIRLLSTSISE
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHH
AAQAATQIAASSKQQMVGMDQVVMAMTNIQQASEQNVAGTKQAESAAQGLYEMGNKLSVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEE
VGSKKDRFVEEAGKVHA
ECCCHHHHHHHHCCCCC
>Mature Secondary Structure 
TISEKIIGGYAIILALLALSTAVAFYALGQTQATYDHFLRVDERLMESANELRIAGFAQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHH
QTYVRGILLYPDLLKTNHALLQDNDRRFKQILEKIRQLRSGNKGDSLLDELQSLHQQLEE
HHHHHHHHCCHHHHHCCCHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
AQQQAVRLSFEQKREEALAFVTNTFRPLSLVFIDKAKHFYEQQSAILESRKIEASDKVSS
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
YTAVLVAVSLFTVLVGLTIGIRLSRMITGRLRESIAQLASSSAEILSTTSQVAAGAAETA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCHHHHH
AAVSETTATVEEVKQTALTTSQKAKYVSDSAQKASNISEAGRKSVGEAISGMNRIQEQME
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIAESIMQLSKQGHAIGEIIATVNDLAEQSNLLAVNAAIEATRAGEQGKSFGVVAREIRS
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCEEEEHHHHHHHHCCCCCCHHHHHHHHHHH
LADQSKQATAQVRTILGDIQKATNAAVLATEQGNKAVEAGVRQSTETDEAIRLLSTSISE
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHH
AAQAATQIAASSKQQMVGMDQVVMAMTNIQQASEQNVAGTKQAESAAQGLYEMGNKLSVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEE
VGSKKDRFVEEAGKVHA
ECCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2492105; 1624419 [H]