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The map label for this gene is mreB [H]

Identifier: 82701454

GI number: 82701454

Start: 345081

End: 346139

Strand: Reverse

Name: mreB [H]

Synonym: Nmul_A0320

Alternate gene names: 82701454

Gene position: 346139-345081 (Counterclockwise)

Preceding gene: 82701461

Following gene: 82701453

Centisome position: 10.87

GC content: 56.56

Gene sequence:

>1059_bases
ATGCTTAATTTTTTAAATAACAGTGTATTGAAGGGTTACTTTTCGACCGACATGGCGATAGATCTGGGGACGGCGAACAC
TCTGATCTACGTGCGCGGTCAAGGCATTGTCCTCAATGAACCCTCAGTGGTAGCGATACGCCAGGATGGGGGTCCCAACG
GCAAGAAAATCATCCAGCAGGTAGGGCTGGCTGCCAAGCAGATGCTCGGGCGCACGCCCGGCAACATCACGGCCATCCGG
CCAATGAAAGATGGCGTCATTGCGGATTTCACCGTTACGGAACAGATGCTGAAGCATTTCATCAGAAAGGTAAATCCTCC
GCGGCTGTTTTCCGCCAACCCGCGGATTGTCATCTGCGTACCCTGCGGTTCGACTCAGGTCGAGCGCCGCGCCATTCGCG
AAGCGGCTTATGGGGCGGGCGCCCGCAAGGTGGAATTGATCGAGGAGCCGGTGGCGGCTGCCATCGGCGCCAATCTGCCG
GTCGATGAAGCCACCGGCTCCATGGTGGTCGATATAGGGGGCGGCACGACCGAAGTCGGTGTGATCTCGCTGGGCGGCGT
CGTTTACTCGAGTTCGGTACGCGTCGGAGGAGACAAGTTTGACGAGGCCATCATCAACTACATACGCCGCAATTACGGGA
TGCTGATCGGTGAAGTAACCGCCGAATTGATCAAGAAGGAAATCGGCTCCGCATTTCCGGGATCGGAAGTACGCGAACTG
GAAGTCAAGGGCCGTAACCTGGCAGAAGGTATTCCACGCAGCTTTACCATTTCGAGCAATGAAGTGCTTGAAGCGCTGAC
CGAGCCGTTGAACAACATCGTAAGCGCTGTCAAATCCGCACTGGAGCATACCGCGCCTGAACTCGGAGCCGATATCGCCG
AAAAAGGCCTGGTGCTCACGGGCGGAGGCGCCCTGCTTCGCGACATCGACCGGCTGCTTATGGAAGAAACCGGACTTTCC
GTCATCATCGCAGAAGACCCGCTTACTGCCGTCGTGCGTGGATCAGGGATTGCACTGGAAAATATGGATCACCTGGTTGG
CATATTCGCCAGTGACTGA

Upstream 100 bases:

>100_bases
TCCTTTATAACCCTTATATTCAAATAGCTAATAGAGTATCATAGCCCGATTCTTTTCACCTGCTTTTAATTACTATCCTC
CGCGACGGACTCCGTAAATC

Downstream 100 bases:

>100_bases
TAACCTTTATAAATTGCGCTACTGCCAGCTCTCACTACCGCCTTCAATGCACCGCACCTTCCAGTCCCTGCAAATCGGGA
ACATAAAATCTCGCACATGA

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MLNFLNNSVLKGYFSTDMAIDLGTANTLIYVRGQGIVLNEPSVVAIRQDGGPNGKKIIQQVGLAAKQMLGRTPGNITAIR
PMKDGVIADFTVTEQMLKHFIRKVNPPRLFSANPRIVICVPCGSTQVERRAIREAAYGAGARKVELIEEPVAAAIGANLP
VDEATGSMVVDIGGGTTEVGVISLGGVVYSSSVRVGGDKFDEAIINYIRRNYGMLIGEVTAELIKKEIGSAFPGSEVREL
EVKGRNLAEGIPRSFTISSNEVLEALTEPLNNIVSAVKSALEHTAPELGADIAEKGLVLTGGGALLRDIDRLLMEETGLS
VIIAEDPLTAVVRGSGIALENMDHLVGIFASD

Sequences:

>Translated_352_residues
MLNFLNNSVLKGYFSTDMAIDLGTANTLIYVRGQGIVLNEPSVVAIRQDGGPNGKKIIQQVGLAAKQMLGRTPGNITAIR
PMKDGVIADFTVTEQMLKHFIRKVNPPRLFSANPRIVICVPCGSTQVERRAIREAAYGAGARKVELIEEPVAAAIGANLP
VDEATGSMVVDIGGGTTEVGVISLGGVVYSSSVRVGGDKFDEAIINYIRRNYGMLIGEVTAELIKKEIGSAFPGSEVREL
EVKGRNLAEGIPRSFTISSNEVLEALTEPLNNIVSAVKSALEHTAPELGADIAEKGLVLTGGGALLRDIDRLLMEETGLS
VIIAEDPLTAVVRGSGIALENMDHLVGIFASD
>Mature_352_residues
MLNFLNNSVLKGYFSTDMAIDLGTANTLIYVRGQGIVLNEPSVVAIRQDGGPNGKKIIQQVGLAAKQMLGRTPGNITAIR
PMKDGVIADFTVTEQMLKHFIRKVNPPRLFSANPRIVICVPCGSTQVERRAIREAAYGAGARKVELIEEPVAAAIGANLP
VDEATGSMVVDIGGGTTEVGVISLGGVVYSSSVRVGGDKFDEAIINYIRRNYGMLIGEVTAELIKKEIGSAFPGSEVREL
EVKGRNLAEGIPRSFTISSNEVLEALTEPLNNIVSAVKSALEHTAPELGADIAEKGLVLTGGGALLRDIDRLLMEETGLS
VIIAEDPLTAVVRGSGIALENMDHLVGIFASD

Specific function: Involved in formation of the rod shape of the cell. May act as a negative regulator of ftsI [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI87082236, Length=336, Percent_Identity=73.5119047619048, Blast_Score=491, Evalue=1e-140,
Organism=Escherichia coli, GI1788875, Length=235, Percent_Identity=28.5106382978723, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001023
- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 37290; Mature: 37290

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNFLNNSVLKGYFSTDMAIDLGTANTLIYVRGQGIVLNEPSVVAIRQDGGPNGKKIIQQ
CCCCCCCHHHHHEECCCEEEEECCCCEEEEEECCEEEECCCCEEEEECCCCCCHHHHHHH
VGLAAKQMLGRTPGNITAIRPMKDGVIADFTVTEQMLKHFIRKVNPPRLFSANPRIVICV
HHHHHHHHHCCCCCCEEEEEECCCCCEEEHHHHHHHHHHHHHHCCCCCEECCCCCEEEEE
PCGSTQVERRAIREAAYGAGARKVELIEEPVAAAIGANLPVDEATGSMVVDIGGGTTEVG
CCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCEEE
VISLGGVVYSSSVRVGGDKFDEAIINYIRRNYGMLIGEVTAELIKKEIGSAFPGSEVREL
EEEECCEEEECCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEE
EVKGRNLAEGIPRSFTISSNEVLEALTEPLNNIVSAVKSALEHTAPELGADIAEKGLVLT
EECCCHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCHHHHHCCEEEE
GGGALLRDIDRLLMEETGLSVIIAEDPLTAVVRGSGIALENMDHLVGIFASD
CCCHHHHHHHHHHHHHCCCEEEEECCCCEEEEECCCCEECCCCCEEEEEECC
>Mature Secondary Structure
MLNFLNNSVLKGYFSTDMAIDLGTANTLIYVRGQGIVLNEPSVVAIRQDGGPNGKKIIQQ
CCCCCCCHHHHHEECCCEEEEECCCCEEEEEECCEEEECCCCEEEEECCCCCCHHHHHHH
VGLAAKQMLGRTPGNITAIRPMKDGVIADFTVTEQMLKHFIRKVNPPRLFSANPRIVICV
HHHHHHHHHCCCCCCEEEEEECCCCCEEEHHHHHHHHHHHHHHCCCCCEECCCCCEEEEE
PCGSTQVERRAIREAAYGAGARKVELIEEPVAAAIGANLPVDEATGSMVVDIGGGTTEVG
CCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCEEE
VISLGGVVYSSSVRVGGDKFDEAIINYIRRNYGMLIGEVTAELIKKEIGSAFPGSEVREL
EEEECCEEEECCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEE
EVKGRNLAEGIPRSFTISSNEVLEALTEPLNNIVSAVKSALEHTAPELGADIAEKGLVLT
EECCCHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCHHHHHCCEEEE
GGGALLRDIDRLLMEETGLSVIIAEDPLTAVVRGSGIALENMDHLVGIFASD
CCCHHHHHHHHHHHHHCCCEEEEECCCCEEEEECCCCEECCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]