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The map label for this gene is atpH

Identifier: 82701441

GI number: 82701441

Start: 329546

End: 330082

Strand: Direct

Name: atpH

Synonym: Nmul_A0307

Alternate gene names: 82701441

Gene position: 329546-330082 (Clockwise)

Preceding gene: 82701440

Following gene: 82701442

Centisome position: 10.35

GC content: 51.58

Gene sequence:

>537_bases
ATGGCCGAAACTCGCACGATTGCCCGGCCTTATGCGGAGGCAGTCTTCAAACTTGCAAAAAACCAGAATGATCTCGCCCG
CTGGGCAGACACATTGCAGTTGGCGGCCGCTGTCGCGGCCGACGAAAATGTCCGTTCATTGATCGGCAACCCCAAGATAT
CTTCCCGAAAACTGGGCGAGCTTTTTTTGAGCGTTTGCGGGAACAGGCTCAATGAAGAAGGTCGCAATTTCATCTTACTG
CTGGCGGAAAACGGCAGGCTTGAAATTTTGCCCGAGGTAAATGAGTTGTATGAGCAACTCAAGACCCGTCATGAAGGCGT
GCTGGATGCCAAAGTTATTTCTGCTTTTGCCATGAGCGATGCTCAATTGAAGGATCTGGTGACTGATCTCGAGGCCAAGT
TCAAGCGCAAGATAGAGGCAAAAGTGAGCGTCGACGCGGATTTGATAGGCGGCGTGATAGTCGAAATAGGCGATGAGGTG
CTTGACGCCTCCGTGCGAGGAAAACTGGAAGCCATGGCTGTTGCACTTAAAAGCTAG

Upstream 100 bases:

>100_bases
GGGCCTGGCGTTGGCGGGGGCTGCCAAGATCCTCCGGCGCGAGGTGGATGAAAAAGCCCACGCCGAACTGCTTGCATCCC
TCAAGGCGGAGCTCTAGCCG

Downstream 100 bases:

>100_bases
GAGTTAACTGAAAAAATGCATTTAAATCCATCCGAGATCAGTGAACTGATCAAAAGCAGAATTGAAGGGCTTGAAGCAAC
CGCCGAAGTCCGGACACAAG

Product: ATP synthase F1 subunit delta

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F(1) sector subunit delta; F-type ATPase subunit delta; F-ATPase subunit delta

Number of amino acids: Translated: 178; Mature: 177

Protein sequence:

>178_residues
MAETRTIARPYAEAVFKLAKNQNDLARWADTLQLAAAVAADENVRSLIGNPKISSRKLGELFLSVCGNRLNEEGRNFILL
LAENGRLEILPEVNELYEQLKTRHEGVLDAKVISAFAMSDAQLKDLVTDLEAKFKRKIEAKVSVDADLIGGVIVEIGDEV
LDASVRGKLEAMAVALKS

Sequences:

>Translated_178_residues
MAETRTIARPYAEAVFKLAKNQNDLARWADTLQLAAAVAADENVRSLIGNPKISSRKLGELFLSVCGNRLNEEGRNFILL
LAENGRLEILPEVNELYEQLKTRHEGVLDAKVISAFAMSDAQLKDLVTDLEAKFKRKIEAKVSVDADLIGGVIVEIGDEV
LDASVRGKLEAMAVALKS
>Mature_177_residues
AETRTIARPYAEAVFKLAKNQNDLARWADTLQLAAAVAADENVRSLIGNPKISSRKLGELFLSVCGNRLNEEGRNFILLL
AENGRLEILPEVNELYEQLKTRHEGVLDAKVISAFAMSDAQLKDLVTDLEAKFKRKIEAKVSVDADLIGGVIVEIGDEVL
DASVRGKLEAMAVALKS

Specific function: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction

COG id: COG0712

COG function: function code C; F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase delta chain family

Homologues:

Organism=Homo sapiens, GI4502303, Length=172, Percent_Identity=30.8139534883721, Blast_Score=70, Evalue=7e-13,
Organism=Escherichia coli, GI1790173, Length=178, Percent_Identity=39.8876404494382, Blast_Score=136, Evalue=8e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATPD_NITMU (Q2YCA6)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_411007.1
- ProteinModelPortal:   Q2YCA6
- SMR:   Q2YCA6
- STRING:   Q2YCA6
- GeneID:   3785340
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A0307
- eggNOG:   COG0712
- HOGENOM:   HBG668108
- OMA:   FIAICGE
- PhylomeDB:   Q2YCA6
- ProtClustDB:   CLSK585214
- BioCyc:   NMUL323848:NMUL_A0307-MONOMER
- HAMAP:   MF_01416
- InterPro:   IPR000711
- Gene3D:   G3DSA:1.10.520.20
- PANTHER:   PTHR11910
- PRINTS:   PR00125
- TIGRFAMs:   TIGR01145

Pfam domain/function: PF00213 OSCP; SSF47928 ATPsynt_OSCP

EC number: 3.6.3.14

Molecular weight: Translated: 19477; Mature: 19345

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00389 ATPASE_DELTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAETRTIARPYAEAVFKLAKNQNDLARWADTLQLAAAVAADENVRSLIGNPKISSRKLGE
CCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHH
LFLSVCGNRLNEEGRNFILLLAENGRLEILPEVNELYEQLKTRHEGVLDAKVISAFAMSD
HHHHHHHHHHCCCCCCEEEEEECCCCEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHCH
AQLKDLVTDLEAKFKRKIEAKVSVDADLIGGVIVEIGDEVLDASVRGKLEAMAVALKS
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AETRTIARPYAEAVFKLAKNQNDLARWADTLQLAAAVAADENVRSLIGNPKISSRKLGE
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHH
LFLSVCGNRLNEEGRNFILLLAENGRLEILPEVNELYEQLKTRHEGVLDAKVISAFAMSD
HHHHHHHHHHCCCCCCEEEEEECCCCEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHCH
AQLKDLVTDLEAKFKRKIEAKVSVDADLIGGVIVEIGDEVLDASVRGKLEAMAVALKS
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA