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The map label for this gene is atpA1

Identifier: 82701442

GI number: 82701442

Start: 330098

End: 331639

Strand: Direct

Name: atpA1

Synonym: Nmul_A0308

Alternate gene names: 82701442

Gene position: 330098-331639 (Clockwise)

Preceding gene: 82701441

Following gene: 82701443

Centisome position: 10.37

GC content: 55.32

Gene sequence:

>1542_bases
ATGCATTTAAATCCATCCGAGATCAGTGAACTGATCAAAAGCAGAATTGAAGGGCTTGAAGCAACCGCCGAAGTCCGGAC
ACAAGGCACGGTGGTTTCCGTGACCGACGGCATCGTGCGCATCCATGGACTGTCTGATGTGATGCAGGGCGAAATGCTTG
AGTTCCCGGGTAATACCTTCGGTCTTGCGCTCAATCTGGAGCGCGATTCAGTGGGCGCGGTTGTTCTGGGTGAGTATGAG
CACATTACCGAGGGCGATACCGTCAAGTGCACGGGCCGCATTCTGGAAGTTCCGGTAGGAGAGGAACTGATCGGCCGTGT
AGTCAACGCGCTGGGGCAGCCCATCGACGGCAAGGGGCCGATAACAACCAAGCACTCCGAGCCGATAGAAAAGATTGCAC
CGGGCGTGGTGTGGCGTCAATCGGTGAATCAGCCGGTGCAGACCGGGCTGAAGGCGATCGACGCAATGGTTCCCATCGGG
CGCGGCCAGCGTGAACTGATCATTGGAGATCGTCAAACGGGAAAAACGGCAGTAGCTGTGGATGCAATCATCAACCAGAA
GGGTGAGAACATGATTTGCATCTACGTTGCGATCGGTCAGAAAGCGTCGTCGATCAGTAACGTAGTGCGGAAGCTGGAAG
AGCATGGGGCGATGGAATATACCATCGTCGTGGCTGCCACCGCTTCGGAGTCGGCCGCGATGCAGTTTATCGCCCCTTAT
TCCGGTTGCACGATGGGCGAGTATTTCCGCGATACCGGCAGGGACGCGCTGATTGTTTATGACGATTTGACCAAGCAAGC
ATGGGCTTATCGGCAGATTTCCCTGTTGTTGCGCCGCCCTCCTGGCCGGGAAGCCTATCCTGGAGATGTGTTTTATTTGC
ACTCGCGGCTGCTGGAACGCGCAGCGCGTGTCAGCGCGGCCTATGTGGAAAAAGAGACGAATGGCGCAGTCAAAGGCAAG
ACGGGTTCGCTGACAGCCTTGCCTGTGATCGAAACCCAGGCGGGTGACGTGACTGCATTCGTTCCCACCAACGTTATCTC
CATTACTGATGGCCAGATTTTTCTGGAATCCGACCTGTTCAATGCAGGTATCCGGCCAGCTATCAACGCCGGTATTTCAG
TCTCTCGTGTAGGGGGCGCCGCGCAGACCAAAGTCATCAAGAAACTGGGTGGCGGCGTGCGTCTCGCATTGGCGCAATAC
CGGGAACTTGCCGCATTTGCCCAGTTCGCCTCCGACCTCGATGAAGCGACACGCAAGCAGCTTGAGCGCGGCAAGATGGT
GACGGAACTGATGAAGCAGCCTCAGTACTCAACCCTGAGCGTATCCGAAATGGCGCTTACCCTGTTTGCCGTCAACAAAG
GATACCTGGATGATGTGGAAGTAAGCCGCGCGTTGGCCTTTGAATCTGCACTCAGAGGTTTCATTCGTAGCAAGTATGGG
GCAATTCTGGACAAGATAGAGACCACCAAGGATCTGGATGCGGAAACCGAGAAGGAACTCGATGCGGCAATCCAGGATTT
CAAGAAAAACGGAACATACTGA

Upstream 100 bases:

>100_bases
CGTGATAGTCGAAATAGGCGATGAGGTGCTTGACGCCTCCGTGCGAGGAAAACTGGAAGCCATGGCTGTTGCACTTAAAA
GCTAGGAGTTAACTGAAAAA

Downstream 100 bases:

>100_bases
CCGATGGCAGGCAGCAGGGAAATACGCAACAAGATCAAAAGCGTAAAGAACACGCAGAAGATCACGCGCGCGATGGAAAT
GGTGGCTGCATCCAAGATGC

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha 1; F-ATPase subunit alpha 1

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MHLNPSEISELIKSRIEGLEATAEVRTQGTVVSVTDGIVRIHGLSDVMQGEMLEFPGNTFGLALNLERDSVGAVVLGEYE
HITEGDTVKCTGRILEVPVGEELIGRVVNALGQPIDGKGPITTKHSEPIEKIAPGVVWRQSVNQPVQTGLKAIDAMVPIG
RGQRELIIGDRQTGKTAVAVDAIINQKGENMICIYVAIGQKASSISNVVRKLEEHGAMEYTIVVAATASESAAMQFIAPY
SGCTMGEYFRDTGRDALIVYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAARVSAAYVEKETNGAVKGK
TGSLTALPVIETQAGDVTAFVPTNVISITDGQIFLESDLFNAGIRPAINAGISVSRVGGAAQTKVIKKLGGGVRLALAQY
RELAAFAQFASDLDEATRKQLERGKMVTELMKQPQYSTLSVSEMALTLFAVNKGYLDDVEVSRALAFESALRGFIRSKYG
AILDKIETTKDLDAETEKELDAAIQDFKKNGTY

Sequences:

>Translated_513_residues
MHLNPSEISELIKSRIEGLEATAEVRTQGTVVSVTDGIVRIHGLSDVMQGEMLEFPGNTFGLALNLERDSVGAVVLGEYE
HITEGDTVKCTGRILEVPVGEELIGRVVNALGQPIDGKGPITTKHSEPIEKIAPGVVWRQSVNQPVQTGLKAIDAMVPIG
RGQRELIIGDRQTGKTAVAVDAIINQKGENMICIYVAIGQKASSISNVVRKLEEHGAMEYTIVVAATASESAAMQFIAPY
SGCTMGEYFRDTGRDALIVYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAARVSAAYVEKETNGAVKGK
TGSLTALPVIETQAGDVTAFVPTNVISITDGQIFLESDLFNAGIRPAINAGISVSRVGGAAQTKVIKKLGGGVRLALAQY
RELAAFAQFASDLDEATRKQLERGKMVTELMKQPQYSTLSVSEMALTLFAVNKGYLDDVEVSRALAFESALRGFIRSKYG
AILDKIETTKDLDAETEKELDAAIQDFKKNGTY
>Mature_513_residues
MHLNPSEISELIKSRIEGLEATAEVRTQGTVVSVTDGIVRIHGLSDVMQGEMLEFPGNTFGLALNLERDSVGAVVLGEYE
HITEGDTVKCTGRILEVPVGEELIGRVVNALGQPIDGKGPITTKHSEPIEKIAPGVVWRQSVNQPVQTGLKAIDAMVPIG
RGQRELIIGDRQTGKTAVAVDAIINQKGENMICIYVAIGQKASSISNVVRKLEEHGAMEYTIVVAATASESAAMQFIAPY
SGCTMGEYFRDTGRDALIVYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAARVSAAYVEKETNGAVKGK
TGSLTALPVIETQAGDVTAFVPTNVISITDGQIFLESDLFNAGIRPAINAGISVSRVGGAAQTKVIKKLGGGVRLALAQY
RELAAFAQFASDLDEATRKQLERGKMVTELMKQPQYSTLSVSEMALTLFAVNKGYLDDVEVSRALAFESALRGFIRSKYG
AILDKIETTKDLDAETEKELDAAIQDFKKNGTY

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI50345984, Length=510, Percent_Identity=56.2745098039216, Blast_Score=582, Evalue=1e-166,
Organism=Homo sapiens, GI4757810, Length=510, Percent_Identity=56.2745098039216, Blast_Score=582, Evalue=1e-166,
Organism=Homo sapiens, GI19913428, Length=312, Percent_Identity=28.525641025641, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI19913426, Length=315, Percent_Identity=27.6190476190476, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI32189394, Length=428, Percent_Identity=24.7663551401869, Blast_Score=113, Evalue=5e-25,
Organism=Homo sapiens, GI19913424, Length=334, Percent_Identity=26.9461077844311, Blast_Score=87, Evalue=5e-17,
Organism=Escherichia coli, GI1790172, Length=513, Percent_Identity=68.8109161793372, Blast_Score=738, Evalue=0.0,
Organism=Escherichia coli, GI1790170, Length=422, Percent_Identity=24.6445497630332, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI1788251, Length=283, Percent_Identity=27.5618374558304, Blast_Score=100, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI71988063, Length=510, Percent_Identity=55.8823529411765, Blast_Score=573, Evalue=1e-164,
Organism=Caenorhabditis elegans, GI71988080, Length=510, Percent_Identity=55.8823529411765, Blast_Score=572, Evalue=1e-163,
Organism=Caenorhabditis elegans, GI71988074, Length=510, Percent_Identity=51.9607843137255, Blast_Score=520, Evalue=1e-148,
Organism=Caenorhabditis elegans, GI17510931, Length=381, Percent_Identity=27.5590551181102, Blast_Score=122, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17570191, Length=306, Percent_Identity=29.0849673202614, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI25144756, Length=476, Percent_Identity=23.9495798319328, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17565854, Length=263, Percent_Identity=28.8973384030418, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=62, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6319370, Length=511, Percent_Identity=55.1859099804305, Blast_Score=567, Evalue=1e-162,
Organism=Saccharomyces cerevisiae, GI6319603, Length=318, Percent_Identity=29.874213836478, Blast_Score=127, Evalue=6e-30,
Organism=Saccharomyces cerevisiae, GI6322581, Length=423, Percent_Identity=25.2955082742317, Blast_Score=122, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6320016, Length=240, Percent_Identity=26.6666666666667, Blast_Score=63, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24658560, Length=510, Percent_Identity=55.4901960784314, Blast_Score=566, Evalue=1e-161,
Organism=Drosophila melanogaster, GI281361666, Length=306, Percent_Identity=28.4313725490196, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24646341, Length=306, Percent_Identity=28.4313725490196, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI17136796, Length=306, Percent_Identity=28.4313725490196, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24638766, Length=387, Percent_Identity=24.2894056847545, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24583988, Length=344, Percent_Identity=27.0348837209302, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24583986, Length=344, Percent_Identity=27.0348837209302, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24583984, Length=344, Percent_Identity=27.0348837209302, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24583992, Length=343, Percent_Identity=27.1137026239067, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI28574560, Length=321, Percent_Identity=23.98753894081, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI20129479, Length=410, Percent_Identity=26.3414634146341, Blast_Score=85, Evalue=1e-16,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPA1_NITMU (Q2YCA5)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_411008.1
- ProteinModelPortal:   Q2YCA5
- SMR:   Q2YCA5
- STRING:   Q2YCA5
- GeneID:   3785341
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A0308
- eggNOG:   COG0056
- HOGENOM:   HBG565875
- OMA:   EMALTLW
- PhylomeDB:   Q2YCA5
- ProtClustDB:   PRK09281
- BioCyc:   NMUL323848:NMUL_A0308-MONOMER
- HAMAP:   MF_01346
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF3
- TIGRFAMs:   TIGR00962

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 55513; Mature: 55513

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHLNPSEISELIKSRIEGLEATAEVRTQGTVVSVTDGIVRIHGLSDVMQGEMLEFPGNTF
CCCCHHHHHHHHHHHHHCCHHHHHHHCCCCEEEEECCEEEEECHHHHHCCCCEECCCCEE
GLALNLERDSVGAVVLGEYEHITEGDTVKCTGRILEVPVGEELIGRVVNALGQPIDGKGP
EEEEEECCCCCCEEEEECCCCCCCCCEEEEECEEEECCCCHHHHHHHHHHHCCCCCCCCC
ITTKHSEPIEKIAPGVVWRQSVNQPVQTGLKAIDAMVPIGRGQRELIIGDRQTGKTAVAV
CCCCCCCCHHHHCCCHHHHHHCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHEEH
DAIINQKGENMICIYVAIGQKASSISNVVRKLEEHGAMEYTIVVAATASESAAMQFIAPY
HHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEEEECCCHHHEEEECCC
SGCTMGEYFRDTGRDALIVYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLER
CCCCHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AARVSAAYVEKETNGAVKGKTGSLTALPVIETQAGDVTAFVPTNVISITDGQIFLESDLF
HHHHHHHHHHHCCCCCEECCCCCEEEEEEEEECCCCEEEEECCCEEEEECCEEEEECCHH
NAGIRPAINAGISVSRVGGAAQTKVIKKLGGGVRLALAQYRELAAFAQFASDLDEATRKQ
CCCCCHHHHCCEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LERGKMVTELMKQPQYSTLSVSEMALTLFAVNKGYLDDVEVSRALAFESALRGFIRSKYG
HHHHHHHHHHHHCCCCCEEEHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AILDKIETTKDLDAETEKELDAAIQDFKKNGTY
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MHLNPSEISELIKSRIEGLEATAEVRTQGTVVSVTDGIVRIHGLSDVMQGEMLEFPGNTF
CCCCHHHHHHHHHHHHHCCHHHHHHHCCCCEEEEECCEEEEECHHHHHCCCCEECCCCEE
GLALNLERDSVGAVVLGEYEHITEGDTVKCTGRILEVPVGEELIGRVVNALGQPIDGKGP
EEEEEECCCCCCEEEEECCCCCCCCCEEEEECEEEECCCCHHHHHHHHHHHCCCCCCCCC
ITTKHSEPIEKIAPGVVWRQSVNQPVQTGLKAIDAMVPIGRGQRELIIGDRQTGKTAVAV
CCCCCCCCHHHHCCCHHHHHHCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHEEH
DAIINQKGENMICIYVAIGQKASSISNVVRKLEEHGAMEYTIVVAATASESAAMQFIAPY
HHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEEEECCCHHHEEEECCC
SGCTMGEYFRDTGRDALIVYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLER
CCCCHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AARVSAAYVEKETNGAVKGKTGSLTALPVIETQAGDVTAFVPTNVISITDGQIFLESDLF
HHHHHHHHHHHCCCCCEECCCCCEEEEEEEEECCCCEEEEECCCEEEEECCEEEEECCHH
NAGIRPAINAGISVSRVGGAAQTKVIKKLGGGVRLALAQYRELAAFAQFASDLDEATRKQ
CCCCCHHHHCCEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LERGKMVTELMKQPQYSTLSVSEMALTLFAVNKGYLDDVEVSRALAFESALRGFIRSKYG
HHHHHHHHHHHHCCCCCEEEHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AILDKIETTKDLDAETEKELDAAIQDFKKNGTY
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA