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The map label for this gene is folE2

Identifier: 82701371

GI number: 82701371

Start: 252177

End: 252968

Strand: Direct

Name: folE2

Synonym: Nmul_A0237

Alternate gene names: 82701371

Gene position: 252177-252968 (Clockwise)

Preceding gene: 82701370

Following gene: 82701372

Centisome position: 7.92

GC content: 50.13

Gene sequence:

>792_bases
ATGAACAAAATGCTCATTGCAGATGTGCAAAGTGTGGCCGATACGAGACGCATTGCCATCGACAAGGCGGGGATCAGGGC
CATCCGCCATCCGGTAAGGATAATGGATAAGGCGGGCGTTCAGCATACAGTGGCCGTATTCAACATGTATGTAAACCTGG
CGCATCACCTCAAAGGCGTGCACATGTCTCGTTTTGTCGAGATGTTGAATGAGCATGATTCGGTAATCTCGGTGGAAACG
TTTGAAAAGCTGCTGATTTCGATGGTGAAGAAGCTCGAGGCGGAATCCGGCGATATCGAAATGCGCTTTCCGTATTTCAT
CGGCAAAACCGCTCCGGTTTCCGGCATAAAGAGTCTGATGGACTATGACGTTACCTTCATCGGACAAACCAGGAACGGAG
AATCCCGCTTCACTTTGAAAGTGGTCGTGCCCGTAACCAGCCTTTGCCCATGCTCCAAAGAGGTATCGGACGATGGAGCG
CACAACCAGCGATCCCATATATCCATATCAATCCGGGCGAATCATTTCGTATGGATAGAAGATCTGATCCGCATCGCGGA
AGACCAGGCCTCCTGTGAGCTCTATGGATTGCTCAAACGCTCGGACGAAAAGTATGTCACCGAGAAGGCCTACGGTAATC
CCAAGTTCGTCGAGGATGCAGTGCGGGATATCGCATCAGTGCTCGATCGGGACGAGCGGATAGACGCTTATACAGTGGAA
GCGGAAAATTTCGAATCCATTCATAATCATTCCGCATATGCGCTGATCGAGTGCGACAAATTGAAGAATTGA

Upstream 100 bases:

>100_bases
GGGATCGTACACGCCATAAGAGCGAGATTCCCGAAGTAAACCGCCCGCTTTTGCATCGCATGCCTTTGATATGCGATGTT
CTTCCTTGCAATGGTACACG

Downstream 100 bases:

>100_bases
CTCCCTCCCGTCTCGATCTGTTTCCCTGCCTCCGGCTGCTTCCCGTTCCCCCTTTCCGGGATAAGATGGAGTAATAAGCG
CAATCCTGCGCTCAAACTGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MNKMLIADVQSVADTRRIAIDKAGIRAIRHPVRIMDKAGVQHTVAVFNMYVNLAHHLKGVHMSRFVEMLNEHDSVISVET
FEKLLISMVKKLEAESGDIEMRFPYFIGKTAPVSGIKSLMDYDVTFIGQTRNGESRFTLKVVVPVTSLCPCSKEVSDDGA
HNQRSHISISIRANHFVWIEDLIRIAEDQASCELYGLLKRSDEKYVTEKAYGNPKFVEDAVRDIASVLDRDERIDAYTVE
AENFESIHNHSAYALIECDKLKN

Sequences:

>Translated_263_residues
MNKMLIADVQSVADTRRIAIDKAGIRAIRHPVRIMDKAGVQHTVAVFNMYVNLAHHLKGVHMSRFVEMLNEHDSVISVET
FEKLLISMVKKLEAESGDIEMRFPYFIGKTAPVSGIKSLMDYDVTFIGQTRNGESRFTLKVVVPVTSLCPCSKEVSDDGA
HNQRSHISISIRANHFVWIEDLIRIAEDQASCELYGLLKRSDEKYVTEKAYGNPKFVEDAVRDIASVLDRDERIDAYTVE
AENFESIHNHSAYALIECDKLKN
>Mature_263_residues
MNKMLIADVQSVADTRRIAIDKAGIRAIRHPVRIMDKAGVQHTVAVFNMYVNLAHHLKGVHMSRFVEMLNEHDSVISVET
FEKLLISMVKKLEAESGDIEMRFPYFIGKTAPVSGIKSLMDYDVTFIGQTRNGESRFTLKVVVPVTSLCPCSKEVSDDGA
HNQRSHISISIRANHFVWIEDLIRIAEDQASCELYGLLKRSDEKYVTEKAYGNPKFVEDAVRDIASVLDRDERIDAYTVE
AENFESIHNHSAYALIECDKLKN

Specific function: Converts GTP to 7,8-dihydroneopterin triphosphate

COG id: COG1469

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase IV family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCH4_NITMU (Q2YCH6)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_410937.1
- ProteinModelPortal:   Q2YCH6
- SMR:   Q2YCH6
- STRING:   Q2YCH6
- GeneID:   3786319
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A0237
- eggNOG:   COG1469
- HOGENOM:   HBG626871
- OMA:   SLMDYEV
- BioCyc:   NMUL323848:NMUL_A0237-MONOMER
- HAMAP:   MF_01527_B
- InterPro:   IPR022838
- InterPro:   IPR003801
- InterPro:   IPR002042
- Gene3D:   G3DSA:3.10.270.10

Pfam domain/function: PF02649 DUF198

EC number: =3.5.4.16

Molecular weight: Translated: 29773; Mature: 29773

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKMLIADVQSVADTRRIAIDKAGIRAIRHPVRIMDKAGVQHTVAVFNMYVNLAHHLKGV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCC
HMSRFVEMLNEHDSVISVETFEKLLISMVKKLEAESGDIEMRFPYFIGKTAPVSGIKSLM
HHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHCCCCCCEEEECCCEECCCCCHHHHHHHH
DYDVTFIGQTRNGESRFTLKVVVPVTSLCPCSKEVSDDGAHNQRSHISISIRANHFVWIE
HCCEEEEEECCCCCCEEEEEEEEECHHCCCCCCCCCCCCCCCCCCEEEEEEECCEEEEHH
DLIRIAEDQASCELYGLLKRSDEKYVTEKAYGNPKFVEDAVRDIASVLDRDERIDAYTVE
HHHHHHCCCCCHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEC
AENFESIHNHSAYALIECDKLKN
CHHHHHHHCCCCEEEEEECCCCC
>Mature Secondary Structure
MNKMLIADVQSVADTRRIAIDKAGIRAIRHPVRIMDKAGVQHTVAVFNMYVNLAHHLKGV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCC
HMSRFVEMLNEHDSVISVETFEKLLISMVKKLEAESGDIEMRFPYFIGKTAPVSGIKSLM
HHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHCCCCCCEEEECCCEECCCCCHHHHHHHH
DYDVTFIGQTRNGESRFTLKVVVPVTSLCPCSKEVSDDGAHNQRSHISISIRANHFVWIE
HCCEEEEEECCCCCCEEEEEEEEECHHCCCCCCCCCCCCCCCCCCEEEEEEECCEEEEHH
DLIRIAEDQASCELYGLLKRSDEKYVTEKAYGNPKFVEDAVRDIASVLDRDERIDAYTVE
HHHHHHCCCCCHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEC
AENFESIHNHSAYALIECDKLKN
CHHHHHHHCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA