Click here to switch to the map view.

The map label for this gene is ftsK2 [H]

Identifier: 82701310

GI number: 82701310

Start: 185213

End: 187543

Strand: Direct

Name: ftsK2 [H]

Synonym: Nmul_A0176

Alternate gene names: 82701310

Gene position: 185213-187543 (Clockwise)

Preceding gene: 82701309

Following gene: 82701312

Centisome position: 5.82

GC content: 57.49

Gene sequence:

>2331_bases
ATGAGCTTCGTCAACAAGCCAATGGCAAAAAAAATCAGTCCCGACCCTTTGCCGCCCAGGGTCGTTCGGCTCCTGCGGGA
GTCGGCGAGTCTTGCCTTGCTGGGGGTGGCGCTCTATCTGGTGCTGATATTTTATGGATATGAGCGCGCCGATCCCGGGT
GGTCGCACAGTGGCGACGGGCCCGCCCAGAATCCTGGGGGCATGGTAGGGGCTTGGCTGTCCGACCTGATGCTGTACTTG
CTGGGTGTTTCCGCCTGGTGGTCAGTGCTGTTTTTCCTTTTCCTGGTATGGTGGATGTATCGCCGCATCGATGGAAGCAT
ATTCGACCGTCGTCCGTGGTTTGTTTCGATGATCGGCTTTCTGCTGTTACTCGTTGCGAGCAGTGGGATGGAAGCACTGC
GTTTCTACTCCCTCAAGGTGGTTTTGCCGCAGATGCCGGGAGGAGTGCTGGGTTTCCTGCTTAGTAAGAGCCTGTCCCAG
GTACTGGGCTTTACTGGCGCAACGTTGGCACTCCTGATATTGATTGCAATCGGTTTCAGTTTATTTACAGGGTTATCCTG
GTTGCGCCTGATCGAGCAGATAGGCGCCTCGATAGAAGGTTTTTTCCTGCTTGTCTGGCGCAGTATAGAAAGCGTCTTCC
TGTTTATCGGCCGTGGCTGGCGGAGCAGGCAGGACCGTCATGTAGGTGCCGTTTCCGCCATCAGGCGTGAAGAGCTGGTG
GAAGTGGAAAAAAAGCGCTTGCTGGAACACCCGCCTTTACACATTGAACAACCGGTTGTCGCGCTTCCCAAGCCGCGCAA
GGTGACCCGGCAAAAGCAGGCTCCCCTTTCTTCTGACCTGCCTGATCCCACTTTGCCGCCGTTGCGCCTGCTCGATGAGC
CGCCAAAGAAAGAAGTGGAAACTCTGTCGACGGAAACACTCGAATTCACTTCCCGCCTGATCGAGCGGAAACTGATGGAT
TTCGGTGTAGAGGTCAAGGTGGTGGCGGCATATCCCGGTCCCGTCATTACACGCTACGAGATTGAGCCTGCCGTCGGGGT
GAAGGGTAACCAGATCCTCAATCTGGTCAAAGACCTGGCGCGATCCTTATCAGTGGTAAGCATCCGTGTCGTCGAGACCA
TTCCGGGGAAGACCTGTATGGGTCTGGAAATCCCCAATCCCAAGCGGCAAGTCGTACGCTTGTCTGAAATTCTCAGTTCA
CAGGCTTATGCCGATATGGGATCGCCCCTGACCATTGCCCTCGGCAAGGATATAGGCGGGCATCCGGTAGTGGCCGATCT
GGCCAAGATGCCGCATTTGCTCGTTGCGGGAACGACCGGCTCGGGCAAATCCGTGGCAATCAATGCGATGTTACTTAGCC
TGCTCTACAAAGCTACGCCCGAGCAGGTGCGTCTCATTCTGGTGGACCCGAAGATGCTTGAATTGTCGGTATATGAGGGC
ATTCCACACCTGTTGGCTCCCGTAGTTACCGACATGCGTCAGGCAGCCAGCGCCCTGCGCTGGGGTGTGGCCGAAATGGA
ACGGCGCTACAAGCTGATGTCAGCGCTTGGGGTCCGTAATCTGGGGGGCTATAACCAGAAAATCCGTGAGGCGATCAAGA
GTGAGAAACCCATCCTCAATCCGCTGAGCCTCACCCCGGAAGCACGGGAACCGCTGGAGGAGATGCCGGTGATTGTCGTG
GTGATAGACGAGCTGGCGGATCTGATGATGGTCGTGGGCAAGAAAGTGGAGGAGTTGATTGCCCGGCTTGCCCAGAAGGC
CCGGGCGGCGGGAGTCCATCTGCTTCTCGCCACTCAGCGGCCTTCCGTGGATGTGATCACAGGACTTATCAAAGCCAATA
TTCCCACACGGGTAGCTTTTCAGGTATCAAGCAAGGTGGACTCGCGCACAATCCTGGACCAGATGGGAGCGGAGGCCTTG
CTCGGGCAGGGCGACATGCTTTATCTGCCCCCCGGAAGCGGATATCCGCAACGGGTTCACGGCGCTTTCGTCGCCGATCA
GGAAGTGCATCGGGTGGTGGAGTATCTCAAGGAACACGGTGAGCCGCGGTATGTGGACGGTGTGCTTGATGCATCGGATG
AGGAAGGCGGCGGGAGCGGAAATGGCGGGGTAGGGGGACAGGAAGGCGGCGAGAGCGATCCGCTTTACGATGAAGCCGTC
GCCATCGTGCTCAGATCTCGACGCGCTTCCATCTCCCTGGTGCAGCGGCACCTGCGCATCGGTTACAACCGGGCTGCGCG
GTTGATTGAAGAAATGGAGCGCGCCGGTCTGGTCTCGGCCATGCAAAGCAACGGCAACCGGGAGATTCTGGTTCCGGCGG
GGAATGAATAA

Upstream 100 bases:

>100_bases
GAAACCCTCCTGTTGCTTATTCCGCTGGAGTGGTTTTATTTTTAACCCCCCATCCAACTCTTATATAATCCATGTTGTTA
CCGTTCCTGCTGCTATATCC

Downstream 100 bases:

>100_bases
AAGGATACCGGCGAGGACGATGTTGGCAAAGGAATCAAGGCGAACGCAGAATGGGGCGGAGGCGATCAGCCGTAATCCGT
TTTTACTGATGGGTTGCGCT

Product: cell division FtsK/SpoIIIE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 776; Mature: 775

Protein sequence:

>776_residues
MSFVNKPMAKKISPDPLPPRVVRLLRESASLALLGVALYLVLIFYGYERADPGWSHSGDGPAQNPGGMVGAWLSDLMLYL
LGVSAWWSVLFFLFLVWWMYRRIDGSIFDRRPWFVSMIGFLLLLVASSGMEALRFYSLKVVLPQMPGGVLGFLLSKSLSQ
VLGFTGATLALLILIAIGFSLFTGLSWLRLIEQIGASIEGFFLLVWRSIESVFLFIGRGWRSRQDRHVGAVSAIRREELV
EVEKKRLLEHPPLHIEQPVVALPKPRKVTRQKQAPLSSDLPDPTLPPLRLLDEPPKKEVETLSTETLEFTSRLIERKLMD
FGVEVKVVAAYPGPVITRYEIEPAVGVKGNQILNLVKDLARSLSVVSIRVVETIPGKTCMGLEIPNPKRQVVRLSEILSS
QAYADMGSPLTIALGKDIGGHPVVADLAKMPHLLVAGTTGSGKSVAINAMLLSLLYKATPEQVRLILVDPKMLELSVYEG
IPHLLAPVVTDMRQAASALRWGVAEMERRYKLMSALGVRNLGGYNQKIREAIKSEKPILNPLSLTPEAREPLEEMPVIVV
VIDELADLMMVVGKKVEELIARLAQKARAAGVHLLLATQRPSVDVITGLIKANIPTRVAFQVSSKVDSRTILDQMGAEAL
LGQGDMLYLPPGSGYPQRVHGAFVADQEVHRVVEYLKEHGEPRYVDGVLDASDEEGGGSGNGGVGGQEGGESDPLYDEAV
AIVLRSRRASISLVQRHLRIGYNRAARLIEEMERAGLVSAMQSNGNREILVPAGNE

Sequences:

>Translated_776_residues
MSFVNKPMAKKISPDPLPPRVVRLLRESASLALLGVALYLVLIFYGYERADPGWSHSGDGPAQNPGGMVGAWLSDLMLYL
LGVSAWWSVLFFLFLVWWMYRRIDGSIFDRRPWFVSMIGFLLLLVASSGMEALRFYSLKVVLPQMPGGVLGFLLSKSLSQ
VLGFTGATLALLILIAIGFSLFTGLSWLRLIEQIGASIEGFFLLVWRSIESVFLFIGRGWRSRQDRHVGAVSAIRREELV
EVEKKRLLEHPPLHIEQPVVALPKPRKVTRQKQAPLSSDLPDPTLPPLRLLDEPPKKEVETLSTETLEFTSRLIERKLMD
FGVEVKVVAAYPGPVITRYEIEPAVGVKGNQILNLVKDLARSLSVVSIRVVETIPGKTCMGLEIPNPKRQVVRLSEILSS
QAYADMGSPLTIALGKDIGGHPVVADLAKMPHLLVAGTTGSGKSVAINAMLLSLLYKATPEQVRLILVDPKMLELSVYEG
IPHLLAPVVTDMRQAASALRWGVAEMERRYKLMSALGVRNLGGYNQKIREAIKSEKPILNPLSLTPEAREPLEEMPVIVV
VIDELADLMMVVGKKVEELIARLAQKARAAGVHLLLATQRPSVDVITGLIKANIPTRVAFQVSSKVDSRTILDQMGAEAL
LGQGDMLYLPPGSGYPQRVHGAFVADQEVHRVVEYLKEHGEPRYVDGVLDASDEEGGGSGNGGVGGQEGGESDPLYDEAV
AIVLRSRRASISLVQRHLRIGYNRAARLIEEMERAGLVSAMQSNGNREILVPAGNE
>Mature_775_residues
SFVNKPMAKKISPDPLPPRVVRLLRESASLALLGVALYLVLIFYGYERADPGWSHSGDGPAQNPGGMVGAWLSDLMLYLL
GVSAWWSVLFFLFLVWWMYRRIDGSIFDRRPWFVSMIGFLLLLVASSGMEALRFYSLKVVLPQMPGGVLGFLLSKSLSQV
LGFTGATLALLILIAIGFSLFTGLSWLRLIEQIGASIEGFFLLVWRSIESVFLFIGRGWRSRQDRHVGAVSAIRREELVE
VEKKRLLEHPPLHIEQPVVALPKPRKVTRQKQAPLSSDLPDPTLPPLRLLDEPPKKEVETLSTETLEFTSRLIERKLMDF
GVEVKVVAAYPGPVITRYEIEPAVGVKGNQILNLVKDLARSLSVVSIRVVETIPGKTCMGLEIPNPKRQVVRLSEILSSQ
AYADMGSPLTIALGKDIGGHPVVADLAKMPHLLVAGTTGSGKSVAINAMLLSLLYKATPEQVRLILVDPKMLELSVYEGI
PHLLAPVVTDMRQAASALRWGVAEMERRYKLMSALGVRNLGGYNQKIREAIKSEKPILNPLSLTPEAREPLEEMPVIVVV
IDELADLMMVVGKKVEELIARLAQKARAAGVHLLLATQRPSVDVITGLIKANIPTRVAFQVSSKVDSRTILDQMGAEALL
GQGDMLYLPPGSGYPQRVHGAFVADQEVHRVVEYLKEHGEPRYVDGVLDASDEEGGGSGNGGVGGQEGGESDPLYDEAVA
IVLRSRRASISLVQRHLRIGYNRAARLIEEMERAGLVSAMQSNGNREILVPAGNE

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=496, Percent_Identity=65.3225806451613, Blast_Score=610, Evalue=1e-175,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 85157; Mature: 85026

Theoretical pI: Translated: 9.11; Mature: 9.11

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFVNKPMAKKISPDPLPPRVVRLLRESASLALLGVALYLVLIFYGYERADPGWSHSGDG
CCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
PAQNPGGMVGAWLSDLMLYLLGVSAWWSVLFFLFLVWWMYRRIDGSIFDRRPWFVSMIGF
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
LLLLVASSGMEALRFYSLKVVLPQMPGGVLGFLLSKSLSQVLGFTGATLALLILIAIGFS
HHHHHHHCCHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LFTGLSWLRLIEQIGASIEGFFLLVWRSIESVFLFIGRGWRSRQDRHVGAVSAIRREELV
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
EVEKKRLLEHPPLHIEQPVVALPKPRKVTRQKQAPLSSDLPDPTLPPLRLLDEPPKKEVE
HHHHHHHHCCCCCCCCCCCEECCCCHHHHHHHCCCCCCCCCCCCCCCHHHCCCCCHHHHH
TLSTETLEFTSRLIERKLMDFGVEVKVVAAYPGPVITRYEIEPAVGVKGNQILNLVKDLA
HHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHH
RSLSVVSIRVVETIPGKTCMGLEIPNPKRQVVRLSEILSSQAYADMGSPLTIALGKDIGG
HHHHHHEEEEEEECCCCEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCC
HPVVADLAKMPHLLVAGTTGSGKSVAINAMLLSLLYKATPEQVRLILVDPKMLELSVYEG
CHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEHHHHHC
IPHLLAPVVTDMRQAASALRWGVAEMERRYKLMSALGVRNLGGYNQKIREAIKSEKPILN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCC
PLSLTPEAREPLEEMPVIVVVIDELADLMMVVGKKVEELIARLAQKARAAGVHLLLATQR
CCCCCCHHHCHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCC
PSVDVITGLIKANIPTRVAFQVSSKVDSRTILDQMGAEALLGQGDMLYLPPGSGYPQRVH
CCHHHHHHHHHCCCCCEEEEEEHHCCHHHHHHHHHCHHHHHCCCCEEEECCCCCCCHHHH
GAFVADQEVHRVVEYLKEHGEPRYVDGVLDASDEEGGGSGNGGVGGQEGGESDPLYDEAV
HHHHCHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
AIVLRSRRASISLVQRHLRIGYNRAARLIEEMERAGLVSAMQSNGNREILVPAGNE
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCC
>Mature Secondary Structure 
SFVNKPMAKKISPDPLPPRVVRLLRESASLALLGVALYLVLIFYGYERADPGWSHSGDG
CCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
PAQNPGGMVGAWLSDLMLYLLGVSAWWSVLFFLFLVWWMYRRIDGSIFDRRPWFVSMIGF
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
LLLLVASSGMEALRFYSLKVVLPQMPGGVLGFLLSKSLSQVLGFTGATLALLILIAIGFS
HHHHHHHCCHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LFTGLSWLRLIEQIGASIEGFFLLVWRSIESVFLFIGRGWRSRQDRHVGAVSAIRREELV
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
EVEKKRLLEHPPLHIEQPVVALPKPRKVTRQKQAPLSSDLPDPTLPPLRLLDEPPKKEVE
HHHHHHHHCCCCCCCCCCCEECCCCHHHHHHHCCCCCCCCCCCCCCCHHHCCCCCHHHHH
TLSTETLEFTSRLIERKLMDFGVEVKVVAAYPGPVITRYEIEPAVGVKGNQILNLVKDLA
HHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHH
RSLSVVSIRVVETIPGKTCMGLEIPNPKRQVVRLSEILSSQAYADMGSPLTIALGKDIGG
HHHHHHEEEEEEECCCCEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCC
HPVVADLAKMPHLLVAGTTGSGKSVAINAMLLSLLYKATPEQVRLILVDPKMLELSVYEG
CHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEHHHHHC
IPHLLAPVVTDMRQAASALRWGVAEMERRYKLMSALGVRNLGGYNQKIREAIKSEKPILN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCC
PLSLTPEAREPLEEMPVIVVVIDELADLMMVVGKKVEELIARLAQKARAAGVHLLLATQR
CCCCCCHHHCHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCC
PSVDVITGLIKANIPTRVAFQVSSKVDSRTILDQMGAEALLGQGDMLYLPPGSGYPQRVH
CCHHHHHHHHHCCCCCEEEEEEHHCCHHHHHHHHHCHHHHHCCCCEEEECCCCCCCHHHH
GAFVADQEVHRVVEYLKEHGEPRYVDGVLDASDEEGGGSGNGGVGGQEGGESDPLYDEAV
HHHHCHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
AIVLRSRRASISLVQRHLRIGYNRAARLIEEMERAGLVSAMQSNGNREILVPAGNE
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]