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The map label for this gene is kdsC [H]

Identifier: 82701223

GI number: 82701223

Start: 90742

End: 91266

Strand: Reverse

Name: kdsC [H]

Synonym: Nmul_A0088

Alternate gene names: 82701223

Gene position: 91266-90742 (Counterclockwise)

Preceding gene: 82701224

Following gene: 82701222

Centisome position: 2.87

GC content: 56.57

Gene sequence:

>525_bases
ATGCAACACATATACGAAAAGGCAAGAAAGATCACGATGGTTATCTTCGATGTGGATGGCGTGCTCACGGACGGGAGCCT
CTATCTCACGGACGGAGGTGAGGAAATCAAAGCGTTCAACAGCCAGGATGGCCATGGCCTGAAAATGCTCAAGGCCACGG
GAGTCAAGGTGGCGCTTATCACTGGCCGTCAGTCCCGCTGTGTGGATTTGAAGGCAAAGGACTGGGGCGTTACCCTCGTC
TATCAAGGCGCAAAAAACAAGCTTCCCGCATTCGAGGCCTTGCTTGAGGACCAGCACCTGGATGCCTCCGCCTGTGCATA
CGTGGGAGATGATCTGATCGATCTGCCGATCCTGCTGCGCTGCGGTCTTGCCATCTCTGTACCTGCCGCCCCTGCCCTCG
TGAAAAAGCACGCGCACTATATCACCCGTCTGGAAGGAGGGCGAGGGGCGGCGCGCGAGATCTGCGAAATGATAATGCAG
GCGCAGGACACGCTGGACGCGCATCTTGCGACTTATCTCACATGA

Upstream 100 bases:

>100_bases
CATCTCCTACTTCTCACCGAGTTTCGGCATTCATACGCATGCAGGGTGCTCCAGAGTTTTTACAAGTTCATTCGATCCGA
CTGTTTCAACCCATAGCAAA

Downstream 100 bases:

>100_bases
TGGGTCACCTTCGCTTCGGATTCCTTTTCGTTATAGTAGCCCTGTTTGCATCATTGCTAACCCTGCTGAATCAGGACGGG
CCCACACCTTTGCTTGCGCC

Product: phosphatase kdsC

Products: NA

Alternate protein names: KDO 8-P phosphatase [H]

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MQHIYEKARKITMVIFDVDGVLTDGSLYLTDGGEEIKAFNSQDGHGLKMLKATGVKVALITGRQSRCVDLKAKDWGVTLV
YQGAKNKLPAFEALLEDQHLDASACAYVGDDLIDLPILLRCGLAISVPAAPALVKKHAHYITRLEGGRGAAREICEMIMQ
AQDTLDAHLATYLT

Sequences:

>Translated_174_residues
MQHIYEKARKITMVIFDVDGVLTDGSLYLTDGGEEIKAFNSQDGHGLKMLKATGVKVALITGRQSRCVDLKAKDWGVTLV
YQGAKNKLPAFEALLEDQHLDASACAYVGDDLIDLPILLRCGLAISVPAAPALVKKHAHYITRLEGGRGAAREICEMIMQ
AQDTLDAHLATYLT
>Mature_174_residues
MQHIYEKARKITMVIFDVDGVLTDGSLYLTDGGEEIKAFNSQDGHGLKMLKATGVKVALITGRQSRCVDLKAKDWGVTLV
YQGAKNKLPAFEALLEDQHLDASACAYVGDDLIDLPILLRCGLAISVPAAPALVKKHAHYITRLEGGRGAAREICEMIMQ
AQDTLDAHLATYLT

Specific function: Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate [H]

COG id: COG1778

COG function: function code R; Low specificity phosphatase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsC family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=153, Percent_Identity=29.4117647058824, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI2367202, Length=163, Percent_Identity=45.398773006135, Blast_Score=154, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006549
- InterPro:   IPR010023 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: =3.1.3.45 [H]

Molecular weight: Translated: 18925; Mature: 18925

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQHIYEKARKITMVIFDVDGVLTDGSLYLTDGGEEIKAFNSQDGHGLKMLKATGVKVALI
CCHHHHHHHEEEEEEEECCCEEECCEEEEECCCHHHEECCCCCCCCEEEEEECCEEEEEE
TGRQSRCVDLKAKDWGVTLVYQGAKNKLPAFEALLEDQHLDASACAYVGDDLIDLPILLR
ECCCCCEEEEEECCCCEEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHH
CGLAISVPAAPALVKKHAHYITRLEGGRGAAREICEMIMQAQDTLDAHLATYLT
CCCEEECCCCHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQHIYEKARKITMVIFDVDGVLTDGSLYLTDGGEEIKAFNSQDGHGLKMLKATGVKVALI
CCHHHHHHHEEEEEEEECCCEEECCEEEEECCCHHHEECCCCCCCCEEEEEECCEEEEEE
TGRQSRCVDLKAKDWGVTLVYQGAKNKLPAFEALLEDQHLDASACAYVGDDLIDLPILLR
ECCCCCEEEEEECCCCEEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHH
CGLAISVPAAPALVKKHAHYITRLEGGRGAAREICEMIMQAQDTLDAHLATYLT
CCCEEECCCCHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]