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The map label for this gene is regA [H]

Identifier: 82701142

GI number: 82701142

Start: 8891

End: 9454

Strand: Reverse

Name: regA [H]

Synonym: Nmul_A0007

Alternate gene names: 82701142

Gene position: 9454-8891 (Counterclockwise)

Preceding gene: 82701143

Following gene: NA

Centisome position: 0.3

GC content: 57.8

Gene sequence:

>564_bases
ATGACAACAACGTTACCCATGACAGAAGTGGATGATCGTCCCGCCTTGCTGATTGTGGATGATGACCAGACCTTTTGTAC
GGTTCTTGCCAATGCAATGACCAAACGCGGATTCACCGTCACCTGCGCGCATAACGTGGATCAGGCACTGGAGCTTGCGG
AGGCCTGCGCCCCGGAGTATGCCGTTGTCGATCTCAGACTGCCCGGTCCTTCCGGATTATCCCTGGTCGAAAAGCTGAAA
GCACTCGATCCCGGCACGCGTATCGTCATGCTGACAGGCTACGCCAGCATCGCTACCGCGGTCGAAGCCATCAAACTCGG
CGCCACCCACTATCTCGCGAAGCCGGTCGACGTTCATGAAATCATGGCGGCGTTCGAGCGCACGACCGGGGATGCAGACG
TGCAGATCAGCGCTCACCCCCTGTCCGTGGGGCGGCTTGAGTGGGAGTATATTCAGCGCGTACTCAACGAGAACAAGGGG
AACGTTTCTGTAACGGCGCGCGTCCTTAACATGCACCGGCGGACATTGCAGCGGAAGCTCACCAAGTATCCCGCGAAAAC
ATGA

Upstream 100 bases:

>100_bases
CAAATGCAAACATCGAACGCTTTGGCGGCAAGGTACGCCTGACCAATCGTGAAGGCGGCGCCTGTACCCAAGTCATACTT
CCTCTGATACAGCCATCGAT

Downstream 100 bases:

>100_bases
GCCGCTCCTTTCATTCTGCCACATCCCGAGAAAGTGTATGCTAACTTACATGAAGATTCAGCAAGAAATAAAAGAATCCA
TTCAAATTATGTAGCCATCC

Product: two component Fis family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MTTTLPMTEVDDRPALLIVDDDQTFCTVLANAMTKRGFTVTCAHNVDQALELAEACAPEYAVVDLRLPGPSGLSLVEKLK
ALDPGTRIVMLTGYASIATAVEAIKLGATHYLAKPVDVHEIMAAFERTTGDADVQISAHPLSVGRLEWEYIQRVLNENKG
NVSVTARVLNMHRRTLQRKLTKYPAKT

Sequences:

>Translated_187_residues
MTTTLPMTEVDDRPALLIVDDDQTFCTVLANAMTKRGFTVTCAHNVDQALELAEACAPEYAVVDLRLPGPSGLSLVEKLK
ALDPGTRIVMLTGYASIATAVEAIKLGATHYLAKPVDVHEIMAAFERTTGDADVQISAHPLSVGRLEWEYIQRVLNENKG
NVSVTARVLNMHRRTLQRKLTKYPAKT
>Mature_186_residues
TTTLPMTEVDDRPALLIVDDDQTFCTVLANAMTKRGFTVTCAHNVDQALELAEACAPEYAVVDLRLPGPSGLSLVEKLKA
LDPGTRIVMLTGYASIATAVEAIKLGATHYLAKPVDVHEIMAAFERTTGDADVQISAHPLSVGRLEWEYIQRVLNENKGN
VSVTARVLNMHRRTLQRKLTKYPAKT

Specific function: Member of the two-component regulatory system regB/regA. Involved in transactivating anaerobic expression of the photosynthetic apparatus. It is a transcriptional regulator that is responsible for activating expression of the puf, puh, and puc operons in

COG id: COG4567

COG function: function code TK; Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=116, Percent_Identity=35.3448275862069, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1788550, Length=112, Percent_Identity=33.0357142857143, Blast_Score=78, Evalue=3e-16,
Organism=Escherichia coli, GI1790299, Length=115, Percent_Identity=33.9130434782609, Blast_Score=75, Evalue=2e-15,
Organism=Escherichia coli, GI1789809, Length=108, Percent_Identity=30.5555555555556, Blast_Score=63, Evalue=9e-12,
Organism=Escherichia coli, GI1786784, Length=108, Percent_Identity=32.4074074074074, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1787375, Length=132, Percent_Identity=31.0606060606061, Blast_Score=61, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR002197
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 20475; Mature: 20344

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTLPMTEVDDRPALLIVDDDQTFCTVLANAMTKRGFTVTCAHNVDQALELAEACAPEY
CCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHCCCCE
AVVDLRLPGPSGLSLVEKLKALDPGTRIVMLTGYASIATAVEAIKLGATHYLAKPVDVHE
EEEEEECCCCCCHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHCCHHHHCCCCCHHH
IMAAFERTTGDADVQISAHPLSVGRLEWEYIQRVLNENKGNVSVTARVLNMHRRTLQRKL
HHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHH
TKYPAKT
HHCCCCC
>Mature Secondary Structure 
TTTLPMTEVDDRPALLIVDDDQTFCTVLANAMTKRGFTVTCAHNVDQALELAEACAPEY
CCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHCCCCE
AVVDLRLPGPSGLSLVEKLKALDPGTRIVMLTGYASIATAVEAIKLGATHYLAKPVDVHE
EEEEEECCCCCCHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHCCHHHHCCCCCHHH
IMAAFERTTGDADVQISAHPLSVGRLEWEYIQRVLNENKGNVSVTARVLNMHRRTLQRKL
HHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHH
TKYPAKT
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA