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The map label for this gene is regB [H]

Identifier: 82701143

GI number: 82701143

Start: 9451

End: 10716

Strand: Reverse

Name: regB [H]

Synonym: Nmul_A0008

Alternate gene names: 82701143

Gene position: 10716-9451 (Counterclockwise)

Preceding gene: 82701151

Following gene: 82701142

Centisome position: 0.34

GC content: 55.61

Gene sequence:

>1266_bases
ATGCTTGTAAATCCCGGCCAGCCACCCCTCCGCAAGAATCTGCAACGTTTATTCCTGCTCCGGAATATCGTCATCGCGGC
CCAGTGCCTGACCTTTGCACTGGCTTACTGGGGGCTCGAACTGGAATTGCCCTGGGCGGAAATGGTCGCGGTTGCGGTCT
TGCTGGGGGTGGTGAACCTGGCGACCTGGATACGTCTCCATCGGAAATGGCCGGTTTCCAGCATGGAGTTCTTTGCACAA
CTCCTGGTGGACGTCCTTGCTTTAAGCACGCTGCTTTATCTCAGCGGCGGCTCGACCAATCCATTTATCTCGCTATACCT
TCTGCCTCTGACTATTGCCGCGGCTGCGCTGCCATGGGCTTATACCTGGGTGATGGCTGCCATCACCATAAGTTGCTATA
CGCTGTTGCTGTTTTATTATGTGCCCCTGCCCCATAACCACGAAGAACATGGCAGCGAATTCATCATGCATGTGTCCGGG
ATGTGGCTGGCTTTCGTCCTGAGCACGGTATTGATCGCGTGGTTCGTTGTCAAGATGGGCATATCGATCCGCGAACGCGA
CAAGGACCTGGCGTTGGCGCGTGAGCAGGCATTGCGTAATGAGCAGATCATTGCGCTCGGAACGCTGGCCGCCGGCGCCG
CGCATGAACTGGGCACCCCGCTGGCAACCATGGCGATAGTCACGGGGGAATTGCAGGACGAATATATCGACGATACCGAA
TTTCAAGGCAATATCAGAATTCTGCGGGATCAGATCGCGCACTGCAAGCGCACCCTGACGCAATTGCTGGCGGATGCGGG
GCAGGCACGCGCCGAAGATGTCAGTGGCCAGACGGTCGATCTTTTTTTGCGCCAGGTTGTGGATAAATGGCAATTGATGC
GGCCCTCTGCCCAGTTTACCTATCGCGGCAGCGGAGTGCAGCCGGCTCCCCAGATTCTGAACACGCAATTGCTGAGCCAG
TCCATTTTGAATCTGTTGAATAATGCGGCGGACGCATCCTTGAAACACATCGAGATAGAAGTTACCTGGAGTCATCAGGA
GCTGCATCTGCAGATACTCGATTATGGAGAAGGACTGAGAGGAGAGGCGGCCCAGCGCGCCGGCCAGCCCTTTTTCACCA
CCAAAACAAAAGGACAGGGTTTCGGCATCGGCCTGTTTCTGGCAAATGCAAACATCGAACGCTTTGGCGGCAAGGTACGC
CTGACCAATCGTGAAGGCGGCGCCTGTACCCAAGTCATACTTCCTCTGATACAGCCATCGATATGA

Upstream 100 bases:

>100_bases
GGCAATATACGCTAATGTTCGGGGATAATATAGCGAAGCCTTGGAGAAGCCCAGGGAAGTTCTCAAGGCTCCCCCGTGCA
CGAGAGAATCCGCGACGAAA

Downstream 100 bases:

>100_bases
CAACAACGTTACCCATGACAGAAGTGGATGATCGTCCCGCCTTGCTGATTGTGGATGATGACCAGACCTTTTGTACGGTT
CTTGCCAATGCAATGACCAA

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: Protein prrB [H]

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MLVNPGQPPLRKNLQRLFLLRNIVIAAQCLTFALAYWGLELELPWAEMVAVAVLLGVVNLATWIRLHRKWPVSSMEFFAQ
LLVDVLALSTLLYLSGGSTNPFISLYLLPLTIAAAALPWAYTWVMAAITISCYTLLLFYYVPLPHNHEEHGSEFIMHVSG
MWLAFVLSTVLIAWFVVKMGISIRERDKDLALAREQALRNEQIIALGTLAAGAAHELGTPLATMAIVTGELQDEYIDDTE
FQGNIRILRDQIAHCKRTLTQLLADAGQARAEDVSGQTVDLFLRQVVDKWQLMRPSAQFTYRGSGVQPAPQILNTQLLSQ
SILNLLNNAADASLKHIEIEVTWSHQELHLQILDYGEGLRGEAAQRAGQPFFTTKTKGQGFGIGLFLANANIERFGGKVR
LTNREGGACTQVILPLIQPSI

Sequences:

>Translated_421_residues
MLVNPGQPPLRKNLQRLFLLRNIVIAAQCLTFALAYWGLELELPWAEMVAVAVLLGVVNLATWIRLHRKWPVSSMEFFAQ
LLVDVLALSTLLYLSGGSTNPFISLYLLPLTIAAAALPWAYTWVMAAITISCYTLLLFYYVPLPHNHEEHGSEFIMHVSG
MWLAFVLSTVLIAWFVVKMGISIRERDKDLALAREQALRNEQIIALGTLAAGAAHELGTPLATMAIVTGELQDEYIDDTE
FQGNIRILRDQIAHCKRTLTQLLADAGQARAEDVSGQTVDLFLRQVVDKWQLMRPSAQFTYRGSGVQPAPQILNTQLLSQ
SILNLLNNAADASLKHIEIEVTWSHQELHLQILDYGEGLRGEAAQRAGQPFFTTKTKGQGFGIGLFLANANIERFGGKVR
LTNREGGACTQVILPLIQPSI
>Mature_421_residues
MLVNPGQPPLRKNLQRLFLLRNIVIAAQCLTFALAYWGLELELPWAEMVAVAVLLGVVNLATWIRLHRKWPVSSMEFFAQ
LLVDVLALSTLLYLSGGSTNPFISLYLLPLTIAAAALPWAYTWVMAAITISCYTLLLFYYVPLPHNHEEHGSEFIMHVSG
MWLAFVLSTVLIAWFVVKMGISIRERDKDLALAREQALRNEQIIALGTLAAGAAHELGTPLATMAIVTGELQDEYIDDTE
FQGNIRILRDQIAHCKRTLTQLLADAGQARAEDVSGQTVDLFLRQVVDKWQLMRPSAQFTYRGSGVQPAPQILNTQLLSQ
SILNLLNNAADASLKHIEIEVTWSHQELHLQILDYGEGLRGEAAQRAGQPFFTTKTKGQGFGIGLFLANANIERFGGKVR
LTNREGGACTQVILPLIQPSI

Specific function: Member of the two-component regulatory system RegB/RegA. Involved in the positive regulation of photosynthesis gene expression in response to anaerobiosis. Also involved in positive regulation of the cbbI and cbbII Calvin cycle CO2 fixation operons, as we

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=258, Percent_Identity=26.3565891472868, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 46708; Mature: 46708

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVNPGQPPLRKNLQRLFLLRNIVIAAQCLTFALAYWGLELELPWAEMVAVAVLLGVVNL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCHHHHHHHHHHHHHHHH
ATWIRLHRKWPVSSMEFFAQLLVDVLALSTLLYLSGGSTNPFISLYLLPLTIAAAALPWA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
YTWVMAAITISCYTLLLFYYVPLPHNHEEHGSEFIMHVSGMWLAFVLSTVLIAWFVVKMG
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ISIRERDKDLALAREQALRNEQIIALGTLAAGAAHELGTPLATMAIVTGELQDEYIDDTE
CCHHHCCHHHHHHHHHHHCCCCEEEEECHHCCCHHHHCCHHHHHHHHHCCHHHHHCCCCC
FQGNIRILRDQIAHCKRTLTQLLADAGQARAEDVSGQTVDLFLRQVVDKWQLMRPSAQFT
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEE
YRGSGVQPAPQILNTQLLSQSILNLLNNAADASLKHIEIEVTWSHQELHLQILDYGEGLR
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCEEEEEEEECCCCCC
GEAAQRAGQPFFTTKTKGQGFGIGLFLANANIERFGGKVRLTNREGGACTQVILPLIQPS
CHHHHHCCCCCEEECCCCCCCEEEEEEECCCHHHCCCEEEEECCCCCHHHHHHHHHHCCC
I
C
>Mature Secondary Structure
MLVNPGQPPLRKNLQRLFLLRNIVIAAQCLTFALAYWGLELELPWAEMVAVAVLLGVVNL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCHHHHHHHHHHHHHHHH
ATWIRLHRKWPVSSMEFFAQLLVDVLALSTLLYLSGGSTNPFISLYLLPLTIAAAALPWA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
YTWVMAAITISCYTLLLFYYVPLPHNHEEHGSEFIMHVSGMWLAFVLSTVLIAWFVVKMG
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ISIRERDKDLALAREQALRNEQIIALGTLAAGAAHELGTPLATMAIVTGELQDEYIDDTE
CCHHHCCHHHHHHHHHHHCCCCEEEEECHHCCCHHHHCCHHHHHHHHHCCHHHHHCCCCC
FQGNIRILRDQIAHCKRTLTQLLADAGQARAEDVSGQTVDLFLRQVVDKWQLMRPSAQFT
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEE
YRGSGVQPAPQILNTQLLSQSILNLLNNAADASLKHIEIEVTWSHQELHLQILDYGEGLR
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCEEEEEEEECCCCCC
GEAAQRAGQPFFTTKTKGQGFGIGLFLANANIERFGGKVRLTNREGGACTQVILPLIQPS
CHHHHHCCCCCEEECCCCCCCEEEEEEECCCHHHCCCEEEEECCCCCHHHHHHHHHHCCC
I
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7751278; 10358089 [H]