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The map label for this gene is frlA [H]

Identifier: 82545727

GI number: 82545727

Start: 3341905

End: 3343293

Strand: Direct

Name: frlA [H]

Synonym: SBO_3358

Alternate gene names: 82545727

Gene position: 3341905-3343293 (Clockwise)

Preceding gene: 82545726

Following gene: 82545728

Centisome position: 73.94

GC content: 54.21

Gene sequence:

>1389_bases
ATGACTGCAAACTCTCCCCTACAACGTGTTGGACAAGAAAAAGGTATCGCTATGGGAAGCCAGGAACTCCAACGCAAGCT
CGGATTTTGGGCCGTTCTTGCAATCGCCGTCGGGACAACCGTCGGCTCCGGTATTTTTGTATCTGTGGGTGAAGTGGCAA
AAGCAGCGGGCACGCCGTGGCTTACGGTGCTCACGTTTGTCATTGGCGGGTTAATTGTGATCCCGCAAATGTGCGTCTAT
GCGGAACTATCCACCGCTTATCCGGAAAATGGCGCAGATTATGTTTATCTGAAAAATGCCGGAAGCCGACCGCTGGCTTT
CCTCTCCGGCTGGGCCAGCTTCTGGGCCAACGATGCGCCGTCATTGTCGATTATGGCGCTGGCGATTGTCAGCAATCTTG
GCTTTTTAACGCCTATCGATCCGTTGCCCGGTAAATTTATCGCCGCCGGATTAATTATCGCCTTTATGTTGCTACACCTG
CGCTCCGTTGAAGGCGGCGCAGCGTTTCAGACGCTAATTACCATCGCCAAAATTATCCCGTTCACTATCGTCATTGGCCT
TGGGATCTTCTGGTTTAAAGCGGAGAATTTTGCCGCCCCTACCACCACTGCGATTGGCGCAACGGGCAGCTTTATGGCGC
TGCTGGCGGGGATCTCTGCCACCAGTTGGTCGTATACCGGCATGGCCTCTATCTGTTATATGACCGGCGAAATTAAAAAC
CCCGGAAAAACCATGCCACGAGCGCTGATTGGTTCCTGTCTGCTGGTTCTGGTGCTCTACACCCTGCTGGCGCTGGTGAT
TTCCGACCTGATGCCCTTCGACAAACTCGCCAATTCTGAAACGCCGATTTCCGACGCCCTGACCTGGATCCCCGCACTCG
GCAGCACCGCTGGGATCTTTGTTGCCATCACGGCGATGATCGTCATTCTTGGTTCGCTTTCCAGCTGCGTGATGTACCAG
CCGCGGCTGGAATACGCGATGGCGAAAGACAACCTGTTCTTTAAATGCTTCGGCCATGTGCATCCGAAATACAACACGCC
GGATGTCTCCATCATCCTGCAAGGGGCGCTGGGGCTCTTCTTCATCTTCGTTTCCGATCTCACCAGCCTGCTGGGTTATT
TCACCCTGGTGATGTGTTTCAAAAATACCCTCACCTTCGGCTCCATCATCTGGTGTCGTAAACGCGACGATTACAAACCG
CTGTGGCGTACTCCTGCTTTCGGGCTGATGACCACCCTCGCCATTGCGTCAAGCCTCATTCTGGTCGCCTCAACCTTTGT
CTGGGCACCGATTCCCGGCCTTATCTGCGCCGTCATCGTTATTGCTACTGGTCTGCCTGCTTACGCCTTCTGGGCGAAGC
GTAGCCGCCAGCTCAACGCTTTGTCGTAA

Upstream 100 bases:

>100_bases
AGCCACAGCGCGATCCTGTGCGAAATTTTGTGATCTTCCTCCGCATTACATAACATCATATGTTATTATATTCATCATGC
ATTGTCATGTTACCTTTTAA

Downstream 100 bases:

>100_bases
TGTTATCTGGAGAAAATAAAATGTTGGATATTGATAAAAGCACCGTGGACTTTCTGGTCACCGAAAATATGGTTCAGGAA
GTGGAAAAAGTTCTCAGCCA

Product: fructoselysine transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 462; Mature: 461

Protein sequence:

>462_residues
MTANSPLQRVGQEKGIAMGSQELQRKLGFWAVLAIAVGTTVGSGIFVSVGEVAKAAGTPWLTVLTFVIGGLIVIPQMCVY
AELSTAYPENGADYVYLKNAGSRPLAFLSGWASFWANDAPSLSIMALAIVSNLGFLTPIDPLPGKFIAAGLIIAFMLLHL
RSVEGGAAFQTLITIAKIIPFTIVIGLGIFWFKAENFAAPTTTAIGATGSFMALLAGISATSWSYTGMASICYMTGEIKN
PGKTMPRALIGSCLLVLVLYTLLALVISDLMPFDKLANSETPISDALTWIPALGSTAGIFVAITAMIVILGSLSSCVMYQ
PRLEYAMAKDNLFFKCFGHVHPKYNTPDVSIILQGALGLFFIFVSDLTSLLGYFTLVMCFKNTLTFGSIIWCRKRDDYKP
LWRTPAFGLMTTLAIASSLILVASTFVWAPIPGLICAVIVIATGLPAYAFWAKRSRQLNALS

Sequences:

>Translated_462_residues
MTANSPLQRVGQEKGIAMGSQELQRKLGFWAVLAIAVGTTVGSGIFVSVGEVAKAAGTPWLTVLTFVIGGLIVIPQMCVY
AELSTAYPENGADYVYLKNAGSRPLAFLSGWASFWANDAPSLSIMALAIVSNLGFLTPIDPLPGKFIAAGLIIAFMLLHL
RSVEGGAAFQTLITIAKIIPFTIVIGLGIFWFKAENFAAPTTTAIGATGSFMALLAGISATSWSYTGMASICYMTGEIKN
PGKTMPRALIGSCLLVLVLYTLLALVISDLMPFDKLANSETPISDALTWIPALGSTAGIFVAITAMIVILGSLSSCVMYQ
PRLEYAMAKDNLFFKCFGHVHPKYNTPDVSIILQGALGLFFIFVSDLTSLLGYFTLVMCFKNTLTFGSIIWCRKRDDYKP
LWRTPAFGLMTTLAIASSLILVASTFVWAPIPGLICAVIVIATGLPAYAFWAKRSRQLNALS
>Mature_461_residues
TANSPLQRVGQEKGIAMGSQELQRKLGFWAVLAIAVGTTVGSGIFVSVGEVAKAAGTPWLTVLTFVIGGLIVIPQMCVYA
ELSTAYPENGADYVYLKNAGSRPLAFLSGWASFWANDAPSLSIMALAIVSNLGFLTPIDPLPGKFIAAGLIIAFMLLHLR
SVEGGAAFQTLITIAKIIPFTIVIGLGIFWFKAENFAAPTTTAIGATGSFMALLAGISATSWSYTGMASICYMTGEIKNP
GKTMPRALIGSCLLVLVLYTLLALVISDLMPFDKLANSETPISDALTWIPALGSTAGIFVAITAMIVILGSLSSCVMYQP
RLEYAMAKDNLFFKCFGHVHPKYNTPDVSIILQGALGLFFIFVSDLTSLLGYFTLVMCFKNTLTFGSIIWCRKRDDYKPL
WRTPAFGLMTTLAIASSLILVASTFVWAPIPGLICAVIVIATGLPAYAFWAKRSRQLNALS

Specific function: May be involved in fructoselysine transport [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI187423910, Length=454, Percent_Identity=26.431718061674, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI7657591, Length=454, Percent_Identity=26.431718061674, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI115648063, Length=409, Percent_Identity=22.9828850855746, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI115648022, Length=409, Percent_Identity=22.9828850855746, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI71979932, Length=477, Percent_Identity=26.4150943396226, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI186910308, Length=444, Percent_Identity=24.3243243243243, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI186910306, Length=444, Percent_Identity=24.3243243243243, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI186910304, Length=444, Percent_Identity=24.3243243243243, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI33286428, Length=466, Percent_Identity=24.4635193133047, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI7657683, Length=476, Percent_Identity=25, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI110347453, Length=368, Percent_Identity=26.6304347826087, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI181337167, Length=351, Percent_Identity=23.9316239316239, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI4507047, Length=166, Percent_Identity=27.710843373494, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI258614003, Length=182, Percent_Identity=27.4725274725275, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI258614005, Length=174, Percent_Identity=27.5862068965517, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI9790235, Length=468, Percent_Identity=22.6495726495727, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI114326544, Length=192, Percent_Identity=23.4375, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI114326550, Length=192, Percent_Identity=23.4375, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI87082250, Length=445, Percent_Identity=99.1011235955056, Blast_Score=879, Evalue=0.0,
Organism=Escherichia coli, GI2367353, Length=349, Percent_Identity=28.9398280802292, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI87082023, Length=396, Percent_Identity=26.5151515151515, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790575, Length=324, Percent_Identity=27.1604938271605, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1788480, Length=272, Percent_Identity=27.2058823529412, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI87081869, Length=412, Percent_Identity=23.3009708737864, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI87081708, Length=369, Percent_Identity=23.5772357723577, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI48994972, Length=321, Percent_Identity=28.3489096573209, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71995382, Length=389, Percent_Identity=26.9922879177378, Blast_Score=115, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI71995388, Length=389, Percent_Identity=26.9922879177378, Blast_Score=115, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI71982608, Length=418, Percent_Identity=25.1196172248804, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71982612, Length=418, Percent_Identity=25.1196172248804, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71993915, Length=388, Percent_Identity=24.7422680412371, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI32566699, Length=375, Percent_Identity=24.2666666666667, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71990446, Length=426, Percent_Identity=24.4131455399061, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17532491, Length=421, Percent_Identity=22.8028503562945, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17531343, Length=415, Percent_Identity=23.1325301204819, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17540018, Length=425, Percent_Identity=24.9411764705882, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI32566695, Length=392, Percent_Identity=23.2142857142857, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI193208714, Length=391, Percent_Identity=23.2736572890026, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71982623, Length=283, Percent_Identity=25.4416961130742, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17533459, Length=399, Percent_Identity=23.0576441102757, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17568033, Length=363, Percent_Identity=24.7933884297521, Blast_Score=73, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6321492, Length=356, Percent_Identity=23.5955056179775, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24667468, Length=402, Percent_Identity=26.1194029850746, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24641995, Length=383, Percent_Identity=26.1096605744125, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24641993, Length=383, Percent_Identity=26.1096605744125, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI21357367, Length=443, Percent_Identity=25.7336343115124, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24651635, Length=366, Percent_Identity=25.4098360655738, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24651633, Length=366, Percent_Identity=25.4098360655738, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI221331183, Length=402, Percent_Identity=24.8756218905473, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI17647653, Length=402, Percent_Identity=24.8756218905473, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24664379, Length=402, Percent_Identity=24.8756218905473, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24666159, Length=450, Percent_Identity=23.3333333333333, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI221512776, Length=450, Percent_Identity=23.3333333333333, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI45550968, Length=462, Percent_Identity=24.8917748917749, Blast_Score=92, Evalue=9e-19,
Organism=Drosophila melanogaster, GI19921172, Length=462, Percent_Identity=24.8917748917749, Blast_Score=92, Evalue=9e-19,
Organism=Drosophila melanogaster, GI281366235, Length=406, Percent_Identity=25.3694581280788, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI116007820, Length=406, Percent_Identity=25.3694581280788, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI116007818, Length=413, Percent_Identity=25.6658595641646, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI85725152, Length=413, Percent_Identity=25.6658595641646, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24668806, Length=412, Percent_Identity=22.3300970873786, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21356285, Length=412, Percent_Identity=22.3300970873786, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24668802, Length=412, Percent_Identity=22.3300970873786, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI161077963, Length=364, Percent_Identity=22.8021978021978, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 49431; Mature: 49300

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTANSPLQRVGQEKGIAMGSQELQRKLGFWAVLAIAVGTTVGSGIFVSVGEVAKAAGTPW
CCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHCCCHH
LTVLTFVIGGLIVIPQMCVYAELSTAYPENGADYVYLKNAGSRPLAFLSGWASFWANDAP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCC
SLSIMALAIVSNLGFLTPIDPLPGKFIAAGLIIAFMLLHLRSVEGGAAFQTLITIAKIIP
CHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
FTIVIGLGIFWFKAENFAAPTTTAIGATGSFMALLAGISATSWSYTGMASICYMTGEIKN
HHHHHHHHHHHEECCCCCCCCCHHHCCCHHHHHHHHCCCCCCCCCCCHHHHHHEECCCCC
PGKTMPRALIGSCLLVLVLYTLLALVISDLMPFDKLANSETPISDALTWIPALGSTAGIF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHCCCCHHHH
VAITAMIVILGSLSSCVMYQPRLEYAMAKDNLFFKCFGHVHPKYNTPDVSIILQGALGLF
HHHHHHHHHHHHHHHHHEECCHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHH
FIFVSDLTSLLGYFTLVMCFKNTLTFGSIIWCRKRDDYKPLWRTPAFGLMTTLAIASSLI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHH
LVASTFVWAPIPGLICAVIVIATGLPAYAFWAKRSRQLNALS
HHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TANSPLQRVGQEKGIAMGSQELQRKLGFWAVLAIAVGTTVGSGIFVSVGEVAKAAGTPW
CCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHCCCHH
LTVLTFVIGGLIVIPQMCVYAELSTAYPENGADYVYLKNAGSRPLAFLSGWASFWANDAP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCC
SLSIMALAIVSNLGFLTPIDPLPGKFIAAGLIIAFMLLHLRSVEGGAAFQTLITIAKIIP
CHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
FTIVIGLGIFWFKAENFAAPTTTAIGATGSFMALLAGISATSWSYTGMASICYMTGEIKN
HHHHHHHHHHHEECCCCCCCCCHHHCCCHHHHHHHHCCCCCCCCCCCHHHHHHEECCCCC
PGKTMPRALIGSCLLVLVLYTLLALVISDLMPFDKLANSETPISDALTWIPALGSTAGIF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHCCCCHHHH
VAITAMIVILGSLSSCVMYQPRLEYAMAKDNLFFKCFGHVHPKYNTPDVSIILQGALGLF
HHHHHHHHHHHHHHHHHEECCHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHH
FIFVSDLTSLLGYFTLVMCFKNTLTFGSIIWCRKRDDYKPLWRTPAFGLMTTLAIASSLI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHH
LVASTFVWAPIPGLICAVIVIATGLPAYAFWAKRSRQLNALS
HHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]