Click here to switch to the map view.

The map label for this gene is frlB [H]

Identifier: 82545728

GI number: 82545728

Start: 3343293

End: 3344336

Strand: Direct

Name: frlB [H]

Synonym: SBO_3359

Alternate gene names: 82545728

Gene position: 3343293-3344336 (Clockwise)

Preceding gene: 82545727

Following gene: 82545729

Centisome position: 73.97

GC content: 54.31

Gene sequence:

>1044_bases
ATGTTATCTGGAGAAAATAAAATGTTGGATATTGATAAAAGCACCGTGGACTTTCTGGTCACCGAAAATATGGTTCAGGA
AGTGGAAAAAGTTCTCAGCCATGACGTTCCGCTGGTGCACGCCATCGTGGAAGAGATGGTGAAGCGCGACATTGATCGTA
TTTATTTCGTTGCCTGCGGCTCGCCACTCAACGCGGCGCAAGCGGCGAAACATCTGGCGGATCGCTTTTCCGATCTTCAG
GTCTACGCCATTTCCGGCTGGGAGTTCTGCGATAACACCCCGTATCGCCTCGACGATCGTTGCGCGGTGATTGGCGTTTC
TGACTACGGTAAAACGGAAGAGGTAATCAAAGCGCTGGAGCTGGGCCGGGCCTGCGGCGCACTCACTGCGGCGTTCACCA
AACGCGCGGACAGCCCGATTACCTCGGCGGCGGAATTTAGCATTGATTATCAGGCCGACTGTATCTGGGAAATTCACCTG
CTGCTCTGCTACAGCGTGGTGCTGGAGATGATCACCCGCCTCGCGCCGAACGCGGAAATCGGCAAGATCAAAAACGATCT
CAAGCAGTTGCCGAATGCGCTCGGTCATCTGGTACGCACCTGGGAAGAAAAAGGCCGCCAGCTTGGTGAACTGGCCAGCC
AGTGGCCGATGATTTATACCGTTGCTGCGGGTCCGCTGCGTCCGCTGGGTTACAAAGAAGGCATTGTAACGCTGATGGAA
TTTACCTGGACGCACGGCTGCGTGATTGAGAGCGGAGAGTTCCGCCATGGCCCGCTGGAGATTGTCGAACCGGGCGTTCC
GTTCCTGTTCCTGCTCGGCAATGATGAAAGTCGCCACACCACCGAACGCGCCATTAACTTTGTTAAACAGCGTACTGACA
ACGTGATCGTCATCGATTACGCCGAAATTTCGCAAGGGCTGCACCCGTGGCTGGCACCGTTCCTGATGTTCGTGCCAATG
GAGTGGCTCTGCTACTACCTGTCTATTTACAAAGATCACAACCCGGATGAACGCCGCTATTACGGTGGTCTGGTGGAATA
TTAA

Upstream 100 bases:

>100_bases
CGATTCCCGGCCTTATCTGCGCCGTCATCGTTATTGCTACTGGTCTGCCTGCTTACGCCTTCTGGGCGAAGCGTAGCCGC
CAGCTCAACGCTTTGTCGTA

Downstream 100 bases:

>100_bases
TCCCTCGCCCGGCCCGGCAACGGGCCGGATTTACGCAAGGAGTTACCCGATGAAAACAGGTATGTTTACCTGCGGCCACC
AGCGGCTGCCTATTGAACAC

Product: fructoselysine-6-P-deglycase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MLSGENKMLDIDKSTVDFLVTENMVQEVEKVLSHDVPLVHAIVEEMVKRDIDRIYFVACGSPLNAAQAAKHLADRFSDLQ
VYAISGWEFCDNTPYRLDDRCAVIGVSDYGKTEEVIKALELGRACGALTAAFTKRADSPITSAAEFSIDYQADCIWEIHL
LLCYSVVLEMITRLAPNAEIGKIKNDLKQLPNALGHLVRTWEEKGRQLGELASQWPMIYTVAAGPLRPLGYKEGIVTLME
FTWTHGCVIESGEFRHGPLEIVEPGVPFLFLLGNDESRHTTERAINFVKQRTDNVIVIDYAEISQGLHPWLAPFLMFVPM
EWLCYYLSIYKDHNPDERRYYGGLVEY

Sequences:

>Translated_347_residues
MLSGENKMLDIDKSTVDFLVTENMVQEVEKVLSHDVPLVHAIVEEMVKRDIDRIYFVACGSPLNAAQAAKHLADRFSDLQ
VYAISGWEFCDNTPYRLDDRCAVIGVSDYGKTEEVIKALELGRACGALTAAFTKRADSPITSAAEFSIDYQADCIWEIHL
LLCYSVVLEMITRLAPNAEIGKIKNDLKQLPNALGHLVRTWEEKGRQLGELASQWPMIYTVAAGPLRPLGYKEGIVTLME
FTWTHGCVIESGEFRHGPLEIVEPGVPFLFLLGNDESRHTTERAINFVKQRTDNVIVIDYAEISQGLHPWLAPFLMFVPM
EWLCYYLSIYKDHNPDERRYYGGLVEY
>Mature_347_residues
MLSGENKMLDIDKSTVDFLVTENMVQEVEKVLSHDVPLVHAIVEEMVKRDIDRIYFVACGSPLNAAQAAKHLADRFSDLQ
VYAISGWEFCDNTPYRLDDRCAVIGVSDYGKTEEVIKALELGRACGALTAAFTKRADSPITSAAEFSIDYQADCIWEIHL
LLCYSVVLEMITRLAPNAEIGKIKNDLKQLPNALGHLVRTWEEKGRQLGELASQWPMIYTVAAGPLRPLGYKEGIVTLME
FTWTHGCVIESGEFRHGPLEIVEPGVPFLFLLGNDESRHTTERAINFVKQRTDNVIVIDYAEISQGLHPWLAPFLMFVPM
EWLCYYLSIYKDHNPDERRYYGGLVEY

Specific function: Catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine [H]

COG id: COG2222

COG function: function code M; Predicted phosphosugar isomerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI205277386, Length=311, Percent_Identity=22.8295819935691, Blast_Score=76, Evalue=4e-14,
Organism=Escherichia coli, GI87082251, Length=340, Percent_Identity=99.7058823529412, Blast_Score=706, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17532899, Length=311, Percent_Identity=24.1157556270096, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17532897, Length=311, Percent_Identity=24.1157556270096, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 39299; Mature: 39299

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSGENKMLDIDKSTVDFLVTENMVQEVEKVLSHDVPLVHAIVEEMVKRDIDRIYFVACG
CCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEEEEEEC
SPLNAAQAAKHLADRFSDLQVYAISGWEFCDNTPYRLDDRCAVIGVSDYGKTEEVIKALE
CCCCHHHHHHHHHHHHCCEEEEEEECCHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHH
LGRACGALTAAFTKRADSPITSAAEFSIDYQADCIWEIHLLLCYSVVLEMITRLAPNAEI
HHHHHHHHHHHHHHHCCCCCCCHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHH
GKIKNDLKQLPNALGHLVRTWEEKGRQLGELASQWPMIYTVAAGPLRPLGYKEGIVTLME
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHH
FTWTHGCVIESGEFRHGPLEIVEPGVPFLFLLGNDESRHTTERAINFVKQRTDNVIVIDY
HHCCCCEEEECCCCCCCCHHEECCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEH
AEISQGLHPWLAPFLMFVPMEWLCYYLSIYKDHNPDERRYYGGLVEY
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCC
>Mature Secondary Structure
MLSGENKMLDIDKSTVDFLVTENMVQEVEKVLSHDVPLVHAIVEEMVKRDIDRIYFVACG
CCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEEEEEEC
SPLNAAQAAKHLADRFSDLQVYAISGWEFCDNTPYRLDDRCAVIGVSDYGKTEEVIKALE
CCCCHHHHHHHHHHHHCCEEEEEEECCHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHH
LGRACGALTAAFTKRADSPITSAAEFSIDYQADCIWEIHLLLCYSVVLEMITRLAPNAEI
HHHHHHHHHHHHHHHCCCCCCCHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHH
GKIKNDLKQLPNALGHLVRTWEEKGRQLGELASQWPMIYTVAAGPLRPLGYKEGIVTLME
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHH
FTWTHGCVIESGEFRHGPLEIVEPGVPFLFLLGNDESRHTTERAINFVKQRTDNVIVIDY
HHCCCCEEEECCCCCCCCHHEECCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEH
AEISQGLHPWLAPFLMFVPMEWLCYYLSIYKDHNPDERRYYGGLVEY
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]