Click here to switch to the map view.

The map label for this gene is pmrD [H]

Identifier: 82544741

GI number: 82544741

Start: 2285442

End: 2285738

Strand: Reverse

Name: pmrD [H]

Synonym: SBO_2296

Alternate gene names: 82544741

Gene position: 2285738-2285442 (Counterclockwise)

Preceding gene: 82544742

Following gene: 82544734

Centisome position: 50.57

GC content: 46.46

Gene sequence:

>297_bases
GTGAAAACTCTTAGCAAACAGGATAATGCAATGGAATGGCTGGTCAAAAAATCGTGCTGCAATAAACAAGATAACAGACA
TGTACTTATGCTCTGCGATGCTGGCGGCGCGATAAAAATGATCGCCGAAGTGAAGAGTGACTTCGCCGTGAAAGTGGGGG
ATTTACTCTCGCCTTTGCAGAATGCGCTTTATTGTATTAATCGTGAAAAGCTGCATACGGTGAAAGTCCTCTCGGCAAGC
AGTTATAGCCCCGATGAGTGGGAACGGCAGTGTACAGCGGCAGGGAAAACTCAGTAA

Upstream 100 bases:

>100_bases
TGGGTGCAACGTCAGCAATAATTAACCCTCCGTTTCACTTCTCATTTCTGCCATTCCATTGCCGTTGATAAAGAGTTTAT
CTGTTAATCTGTAAATTGAT

Downstream 100 bases:

>100_bases
CGTTGTTTTGTCGTGGGCAGGAAAATCAGCATCAACCCGCTCATAATACAGGCTACTCCCAGTAGTGCTTTCAGCGAAAA
AGTCCCTTCCCAGCCGGGAA

Product: polymyxin resistance protein B

Products: NA

Alternate protein names: BasR post-transcriptional activator; Polymyxin resistance protein pmrD [H]

Number of amino acids: Translated: 98; Mature: 98

Protein sequence:

>98_residues
MKTLSKQDNAMEWLVKKSCCNKQDNRHVLMLCDAGGAIKMIAEVKSDFAVKVGDLLSPLQNALYCINREKLHTVKVLSAS
SYSPDEWERQCTAAGKTQ

Sequences:

>Translated_98_residues
MKTLSKQDNAMEWLVKKSCCNKQDNRHVLMLCDAGGAIKMIAEVKSDFAVKVGDLLSPLQNALYCINREKLHTVKVLSAS
SYSPDEWERQCTAAGKTQ
>Mature_98_residues
MKTLSKQDNAMEWLVKKSCCNKQDNRHVLMLCDAGGAIKMIAEVKSDFAVKVGDLLSPLQNALYCINREKLHTVKVLSAS
SYSPDEWERQCTAAGKTQ

Specific function: Interacts with phosphorylated BasR protein to mediate transcriptional induction of BasR-activated genes to induce polymyxin resistance in some natural isolates [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pmrD family [H]

Homologues:

Organism=Escherichia coli, GI87082076, Length=88, Percent_Identity=97.7272727272727, Blast_Score=181, Evalue=6e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020146
- ProDom:   PD028730 [H]

Pfam domain/function: PF11183 PmrD [H]

EC number: NA

Molecular weight: Translated: 10933; Mature: 10933

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.1 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
9.2 %Cys+Met (Translated Protein)
5.1 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
9.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLSKQDNAMEWLVKKSCCNKQDNRHVLMLCDAGGAIKMIAEVKSDFAVKVGDLLSPLQ
CCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHCHHHHHHHHHHHHH
NALYCINREKLHTVKVLSASSYSPDEWERQCTAAGKTQ
HHHHHHCCCCHHEEEEEECCCCCCHHHHHHHCCCCCCC
>Mature Secondary Structure
MKTLSKQDNAMEWLVKKSCCNKQDNRHVLMLCDAGGAIKMIAEVKSDFAVKVGDLLSPLQ
CCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHCHHHHHHHHHHHHH
NALYCINREKLHTVKVLSASSYSPDEWERQCTAAGKTQ
HHHHHHCCCCHHEEEEEECCCCCCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8626063; 9205837; 9278503 [H]