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The map label for this gene is ybgR [H]

Identifier: 82543172

GI number: 82543172

Start: 627534

End: 628475

Strand: Reverse

Name: ybgR [H]

Synonym: SBO_0607

Alternate gene names: 82543172

Gene position: 628475-627534 (Counterclockwise)

Preceding gene: 82543173

Following gene: 82543159

Centisome position: 13.9

GC content: 53.18

Gene sequence:

>942_bases
ATGGCGCACTCACACTCACACACGTCCTCACACCTGCCAGAAGATAATAATGCTCGTCGCTTGTTGTATGCTTTCGGCGT
GACTGCCGGGTTTATGCTGGTAGAAGTCGTTGGTGGTTTTCTTTCTGGTTCTCTGGCATTGCTGGCCGATGCGGGTCATA
TGTTGACCGATACTGCCGCCCTGCTTTTCGCCCTACTCGCCGTGCAATTTTCACGTCGTCCTCCCACCATTCGCCACACT
TTCGGTTGGCTAAGACTGACCACGCTCGCGGCGTTTGTGAATGCCATCGCCCTCGTGGTAATTACCATTTTGATTGTCTG
GGAGGCGATAGAACGCTTCCGCACGCCGCGTCCGGTCGAGGGCGGCATGATGATGGCAATTGCCGTGGCTGGGTTGCTGG
CAAATATACTTTCTTTCTGGTTACTTCATCACGGCAGCGAAGAGAAAAACCTCAACGTACGAGCAGCGGCATTGCATGTG
CTCGGGGACCTGTTGGGTTCGGTTGGGGCTATTATTGCCGCGTTGATTATTATCTGGACCGGCTGGACACCTGCTGACCC
CATTCTCTCGATAGTGGTGTCGCTTCTGGTTCTGCGTAGCGCGTGGCGACTGTTGAAAGATAGCGTGAATGAATTACTTG
AAGGTGCACCGGTATCGCTGGATATCGCTGAACTGAAGCGTCGTATGTGCCGGGAAATCCCGGAAGTCCGCAATGTGCAC
CATGTACATGTATGGATGGTAGGTGAGAAGCCGGTGATGACGCTGCATGTGCAGGTGATCCCGCCACACGCTCACGATGC
CTTGTTGGATCAGATCCAACACTACCTGATGGATCACTATCAGATTGAGCACGCCACCATTCAGATGGAATATCAACCTT
GTCATGGGCCAGACTGCCACCTGAATGAAGGGGTGTCTGGCCATTCACATCATCACCATTAA

Upstream 100 bases:

>100_bases
CCAATAATGGGAGAGCGGAGTCTCTCCCTTTTAATTTTTCACTTCTAAAAGCAGTATGATGTCATAAAGTTAAGTGAGAA
TAATTAAGGGATGACTCGTC

Downstream 100 bases:

>100_bases
TGGGACAGCGCGCATGAGCCTCTTTCACGTGCGCTGTTGATCCACATCCGACTGCCGTTGAGCGCAATAAAGGTCAGGAT
GATGTACTCCAGAGACATGG

Product: zinc transporter ZitB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MAHSHSHTSSHLPEDNNARRLLYAFGVTAGFMLVEVVGGFLSGSLALLADAGHMLTDTAALLFALLAVQFSRRPPTIRHT
FGWLRLTTLAAFVNAIALVVITILIVWEAIERFRTPRPVEGGMMMAIAVAGLLANILSFWLLHHGSEEKNLNVRAAALHV
LGDLLGSVGAIIAALIIIWTGWTPADPILSIVVSLLVLRSAWRLLKDSVNELLEGAPVSLDIAELKRRMCREIPEVRNVH
HVHVWMVGEKPVMTLHVQVIPPHAHDALLDQIQHYLMDHYQIEHATIQMEYQPCHGPDCHLNEGVSGHSHHHH

Sequences:

>Translated_313_residues
MAHSHSHTSSHLPEDNNARRLLYAFGVTAGFMLVEVVGGFLSGSLALLADAGHMLTDTAALLFALLAVQFSRRPPTIRHT
FGWLRLTTLAAFVNAIALVVITILIVWEAIERFRTPRPVEGGMMMAIAVAGLLANILSFWLLHHGSEEKNLNVRAAALHV
LGDLLGSVGAIIAALIIIWTGWTPADPILSIVVSLLVLRSAWRLLKDSVNELLEGAPVSLDIAELKRRMCREIPEVRNVH
HVHVWMVGEKPVMTLHVQVIPPHAHDALLDQIQHYLMDHYQIEHATIQMEYQPCHGPDCHLNEGVSGHSHHHH
>Mature_312_residues
AHSHSHTSSHLPEDNNARRLLYAFGVTAGFMLVEVVGGFLSGSLALLADAGHMLTDTAALLFALLAVQFSRRPPTIRHTF
GWLRLTTLAAFVNAIALVVITILIVWEAIERFRTPRPVEGGMMMAIAVAGLLANILSFWLLHHGSEEKNLNVRAAALHVL
GDLLGSVGAIIAALIIIWTGWTPADPILSIVVSLLVLRSAWRLLKDSVNELLEGAPVSLDIAELKRRMCREIPEVRNVHH
VHVWMVGEKPVMTLHVQVIPPHAHDALLDQIQHYLMDHYQIEHATIQMEYQPCHGPDCHLNEGVSGHSHHHH

Specific function: Involved in zinc efflux across the cytoplasmic membrane, thus reducing zinc accumulation in the cytoplasm and rendering bacteria more resistant to zinc. It may contribute to zinc homeostasis at low concentrations of zinc, whereas zntA is required for grow

COG id: COG1230

COG function: function code P; Co/Zn/Cd efflux system component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily [H]

Homologues:

Organism=Homo sapiens, GI52352805, Length=320, Percent_Identity=32.5, Blast_Score=161, Evalue=6e-40,
Organism=Homo sapiens, GI289803013, Length=320, Percent_Identity=32.5, Blast_Score=146, Evalue=2e-35,
Organism=Homo sapiens, GI289803009, Length=320, Percent_Identity=32.5, Blast_Score=146, Evalue=2e-35,
Organism=Homo sapiens, GI289803007, Length=320, Percent_Identity=32.5, Blast_Score=146, Evalue=2e-35,
Organism=Homo sapiens, GI289803003, Length=320, Percent_Identity=32.5, Blast_Score=146, Evalue=2e-35,
Organism=Homo sapiens, GI21359890, Length=289, Percent_Identity=32.1799307958478, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI64762489, Length=320, Percent_Identity=32.5, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI21361112, Length=309, Percent_Identity=33.3333333333333, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI20070323, Length=348, Percent_Identity=25.2873563218391, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI14210520, Length=231, Percent_Identity=29.004329004329, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI52352803, Length=132, Percent_Identity=43.9393939393939, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI52351208, Length=162, Percent_Identity=29.0123456790123, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI222080086, Length=129, Percent_Identity=27.1317829457364, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI40255009, Length=129, Percent_Identity=27.1317829457364, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1786966, Length=313, Percent_Identity=99.3610223642172, Blast_Score=626, Evalue=0.0,
Organism=Escherichia coli, GI1790349, Length=276, Percent_Identity=23.9130434782609, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193210990, Length=321, Percent_Identity=33.3333333333333, Blast_Score=167, Evalue=9e-42,
Organism=Caenorhabditis elegans, GI17555794, Length=312, Percent_Identity=32.6923076923077, Blast_Score=152, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17555796, Length=310, Percent_Identity=32.258064516129, Blast_Score=148, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI32564488, Length=303, Percent_Identity=31.3531353135314, Blast_Score=134, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI17550440, Length=129, Percent_Identity=31.7829457364341, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17550442, Length=129, Percent_Identity=31.7829457364341, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6320411, Length=179, Percent_Identity=35.7541899441341, Blast_Score=93, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6323899, Length=132, Percent_Identity=36.3636363636364, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6324892, Length=120, Percent_Identity=37.5, Blast_Score=87, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24656728, Length=346, Percent_Identity=29.4797687861272, Blast_Score=131, Evalue=7e-31,
Organism=Drosophila melanogaster, GI24656724, Length=346, Percent_Identity=29.4797687861272, Blast_Score=131, Evalue=7e-31,
Organism=Drosophila melanogaster, GI24656720, Length=346, Percent_Identity=29.4797687861272, Blast_Score=131, Evalue=7e-31,
Organism=Drosophila melanogaster, GI24656715, Length=346, Percent_Identity=29.4797687861272, Blast_Score=131, Evalue=7e-31,
Organism=Drosophila melanogaster, GI21357035, Length=346, Percent_Identity=29.4797687861272, Blast_Score=131, Evalue=7e-31,
Organism=Drosophila melanogaster, GI24583858, Length=321, Percent_Identity=28.9719626168224, Blast_Score=117, Evalue=7e-27,
Organism=Drosophila melanogaster, GI24585900, Length=125, Percent_Identity=32.8, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24585898, Length=125, Percent_Identity=32.8, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24585896, Length=125, Percent_Identity=32.8, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI19921672, Length=125, Percent_Identity=32.8, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24584409, Length=157, Percent_Identity=31.2101910828025, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28574430, Length=157, Percent_Identity=31.2101910828025, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24645863, Length=127, Percent_Identity=30.7086614173228, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24667550, Length=290, Percent_Identity=23.7931034482759, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24667546, Length=290, Percent_Identity=23.7931034482759, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002524 [H]

Pfam domain/function: PF01545 Cation_efflux [H]

EC number: NA

Molecular weight: Translated: 34621; Mature: 34490

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS00511 CRF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHSHSHTSSHLPEDNNARRLLYAFGVTAGFMLVEVVGGFLSGSLALLADAGHMLTDTAA
CCCCCCCCHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHH
LLFALLAVQFSRRPPTIRHTFGWLRLTTLAAFVNAIALVVITILIVWEAIERFRTPRPVE
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GGMMMAIAVAGLLANILSFWLLHHGSEEKNLNVRAAALHVLGDLLGSVGAIIAALIIIWT
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GWTPADPILSIVVSLLVLRSAWRLLKDSVNELLEGAPVSLDIAELKRRMCREIPEVRNVH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHCCCE
HVHVWMVGEKPVMTLHVQVIPPHAHDALLDQIQHYLMDHYQIEHATIQMEYQPCHGPDCH
EEEEEEECCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHEEEEEEEEEEECCCCCCCCC
LNEGVSGHSHHHH
CCCCCCCCCCCCC
>Mature Secondary Structure 
AHSHSHTSSHLPEDNNARRLLYAFGVTAGFMLVEVVGGFLSGSLALLADAGHMLTDTAA
CCCCCCCHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHH
LLFALLAVQFSRRPPTIRHTFGWLRLTTLAAFVNAIALVVITILIVWEAIERFRTPRPVE
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GGMMMAIAVAGLLANILSFWLLHHGSEEKNLNVRAAALHVLGDLLGSVGAIIAALIIIWT
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GWTPADPILSIVVSLLVLRSAWRLLKDSVNELLEGAPVSLDIAELKRRMCREIPEVRNVH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHCCCE
HVHVWMVGEKPVMTLHVQVIPPHAHDALLDQIQHYLMDHYQIEHATIQMEYQPCHGPDCH
EEEEEEECCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHEEEEEEEEEEECCCCCCCCC
LNEGVSGHSHHHH
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 11443104 [H]