Click here to switch to the map view.

The map label for this gene is queC [H]

Identifier: 78780169

GI number: 78780169

Start: 1676771

End: 1677445

Strand: Direct

Name: queC [H]

Synonym: PMT9312_1784

Alternate gene names: 78780169

Gene position: 1676771-1677445 (Clockwise)

Preceding gene: 78780168

Following gene: 78780170

Centisome position: 98.1

GC content: 32.15

Gene sequence:

>675_bases
ATGACTCTTAAAAATAAATCAATAGTAGTTTTGTTATCGGGAGGATTAGATTCCTCTACTGTGACTAGTATCGCAAAAAA
ATCCGAAGCTAAAATTTTTGGCCTTTCATTTGACTACGGTCAACGCCATAAAAAAGAATTACACTCTGCATCAACTATTG
CAAAACACTTTGATATCCAAGAATTTAAAATCATTAAACTTGACTTATCTTTATGGGGAGGCTCTTCATTAACTGATACT
AAGAAAAATATTCCTACAGAGGGAGTTCAAACTAATAAAATTCCTAATACTTATGTTCCTGGGAGAAATACTATATTCAT
TTCCGTCGCACTAAGTTACGCAGAAGCAATAGATGCTGATTTTATAGGCTTAGGAGTTAATGCACTTGATTATTCTGGTT
ATCCAGATTGCAGACCTGACTACATTAAAAAATTTCAAGAATTAGCAGATCTTGCCAACAAAAGAGGAAGAGAAAATAAC
CCAATAAAACTTTGGACGCCTTTATTAGATTTAAATAAAGAACAAATTATTCAATTAGCTATGGATAATCATGTCCCTTT
AGATAAAACATGGAGTTGTTATTCAGGTGATGCAAAACCATGCGGAAAGTGTGATAGTTGCAGAATTAGGAATACCGCTT
ATAAAAAATGGCTCAATAATAAAAATAAAAAATGA

Upstream 100 bases:

>100_bases
TAAAGATGGGTTTTCTCTTGCTATTGATTTCGTAAAAAATAACCCCGATTGGAAATTGAGCCTTCAAACTCACAAATACT
TGAAAATTAAATGAAATTAT

Downstream 100 bases:

>100_bases
AAATAAAAACAATACTTTTAAAAAGATGGGTAGATCCAGAACTAATTACGTACCATCTAACAAAAAAATTTGGAGATAAA
GGATTAGCTTGGTTAGACAG

Product: ExsB

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC [H]

Number of amino acids: Translated: 224; Mature: 223

Protein sequence:

>224_residues
MTLKNKSIVVLLSGGLDSSTVTSIAKKSEAKIFGLSFDYGQRHKKELHSASTIAKHFDIQEFKIIKLDLSLWGGSSLTDT
KKNIPTEGVQTNKIPNTYVPGRNTIFISVALSYAEAIDADFIGLGVNALDYSGYPDCRPDYIKKFQELADLANKRGRENN
PIKLWTPLLDLNKEQIIQLAMDNHVPLDKTWSCYSGDAKPCGKCDSCRIRNTAYKKWLNNKNKK

Sequences:

>Translated_224_residues
MTLKNKSIVVLLSGGLDSSTVTSIAKKSEAKIFGLSFDYGQRHKKELHSASTIAKHFDIQEFKIIKLDLSLWGGSSLTDT
KKNIPTEGVQTNKIPNTYVPGRNTIFISVALSYAEAIDADFIGLGVNALDYSGYPDCRPDYIKKFQELADLANKRGRENN
PIKLWTPLLDLNKEQIIQLAMDNHVPLDKTWSCYSGDAKPCGKCDSCRIRNTAYKKWLNNKNKK
>Mature_223_residues
TLKNKSIVVLLSGGLDSSTVTSIAKKSEAKIFGLSFDYGQRHKKELHSASTIAKHFDIQEFKIIKLDLSLWGGSSLTDTK
KNIPTEGVQTNKIPNTYVPGRNTIFISVALSYAEAIDADFIGLGVNALDYSGYPDCRPDYIKKFQELADLANKRGRENNP
IKLWTPLLDLNKEQIIQLAMDNHVPLDKTWSCYSGDAKPCGKCDSCRIRNTAYKKWLNNKNKK

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) [H]

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family [H]

Homologues:

Organism=Escherichia coli, GI1786648, Length=222, Percent_Identity=33.3333333333333, Blast_Score=124, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018317
- InterPro:   IPR014729 [H]

Pfam domain/function: PF06508 ExsB [H]

EC number: NA

Molecular weight: Translated: 25075; Mature: 24944

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLKNKSIVVLLSGGLDSSTVTSIAKKSEAKIFGLSFDYGQRHKKELHSASTIAKHFDIQ
CCCCCCEEEEEEECCCCHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCC
EFKIIKLDLSLWGGSSLTDTKKNIPTEGVQTNKIPNTYVPGRNTIFISVALSYAEAIDAD
CEEEEEEEEEECCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEEEHHHHHHCCC
FIGLGVNALDYSGYPDCRPDYIKKFQELADLANKRGRENNPIKLWTPLLDLNKEQIIQLA
EEECCCEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHCCHHHHHHHH
MDNHVPLDKTWSCYSGDAKPCGKCDSCRIRNTAYKKWLNNKNKK
HCCCCCCCCCCCCCCCCCCCCCCCCCCEECHHHHHHHHCCCCCC
>Mature Secondary Structure 
TLKNKSIVVLLSGGLDSSTVTSIAKKSEAKIFGLSFDYGQRHKKELHSASTIAKHFDIQ
CCCCCEEEEEEECCCCHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCC
EFKIIKLDLSLWGGSSLTDTKKNIPTEGVQTNKIPNTYVPGRNTIFISVALSYAEAIDAD
CEEEEEEEEEECCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEEEHHHHHHCCC
FIGLGVNALDYSGYPDCRPDYIKKFQELADLANKRGRENNPIKLWTPLLDLNKEQIIQLA
EEECCCEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHCCHHHHHHHH
MDNHVPLDKTWSCYSGDAKPCGKCDSCRIRNTAYKKWLNNKNKK
HCCCCCCCCCCCCCCCCCCCCCCCCCCEECHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA