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The map label for this gene is mnmG

Identifier: 78780152

GI number: 78780152

Start: 1658945

End: 1660933

Strand: Direct

Name: mnmG

Synonym: PMT9312_1767

Alternate gene names: 78780152

Gene position: 1658945-1660933 (Clockwise)

Preceding gene: 78780151

Following gene: 78780153

Centisome position: 97.06

GC content: 33.08

Gene sequence:

>1989_bases
ATGCAAGATCATCACTCAACAAATGAATCTTTTGACATTGTCGTCATTGGAGGAGGACATGCGGGATGTGAAGCAGCTAT
AACATCAGCAAAATTAGGATTTTCTACAGCCTTATTCACAATCAATTTAGATAGGATTGCCTGGCAACCTTGTAACCCTG
CAGTTGGCGGGCCAGCAAAAAGTCAGTTAGTGCATGAAGTTGATGCATTAGGAGGAATCATTGGAAAATTAGCTGATAAA
ACAGCTATACAAAAAAGAATATTAAATGCAAGTAAAGGACCAGCTGTATGGGCATTAAGAGCTCAAACAGATAAAAGAGA
ATACTCAAAAAAGATGATCGAAATCCTTCAAAATACAGATAATTTATCTTTAAAAGAAGCAATGATTACTGAACTGGATA
TTGCAAAGACTGAAGAAATTGGATTGAACTCAAAAAAAATCGTAAAAAAAAGAATAAAGGGTGTCAGGACTTTCTTTGGT
AGTTATTATTCAGCAAGATCAGTTATCATCACAGCTGGTACGTTCTTAGAAGGAAGAATATGGATAGGAAATAAATCAAT
GTCAGCTGGTAGATCGGGCGAACAAGCAGCAAAAGGTCTTACTAAAAATTTGCACGAAATTGGTATCAAAACAGAACGTT
TAAAAACAGGAACTCCAGCAAGAGTTGATAAAAGAAGTATAATTTTTGATGAATTAGATGCTCAACCAAGTACTGCAGCA
GATAAATATTTTTCGTTTGACCCAAATATAAAAAATAATATGCCCCAAGTTAGTTGTCACATAACAAGAACAACTACCAA
AACACATCAACTAATTCGAGACAATTTACATTTAACTCCCATTTACGGCGGTTTTATTGATAGTAAGGGGCCAAGATATT
GTCCATCAATTGAAGATAAAATCGTTAAATTTGCTGATAAAGAATCACATCAAATTTTCTTAGAACCAGAAGGAATTAAT
ACCCCTGAAATATATGTACAAGGATTTTCTACAGGTTTACCCGAAAATATTCAATTAGAACTTTTAAGAACCTTACCTGG
ATTAAGTGAATGTAAAATGTTGCGACCAGCATATGCTGTCGAGTACGACTATATACCTGCAACACAGCTCCAAACATCAC
TAGAAACGAAAGAAATTGAATATTTATTTAGCGCTGGACAAATTAATGGAACTACTGGTTATGAAGAAGCAGCAGCACAA
GGATTAGTTGCAGGAGTCAATGCGACAAGAAAACTAAACGAAAAAGACCCAATAATCTTCACTAGAGAAAGCAGTTATAT
AGGAACAATGATCAATGATTTAATTACCAAAGATCTCAAAGAACCATACAGAGTTCTCACTAGTAGGAGTGAATATAGGT
TAACTCTTAGAGGAGATAATGCAGATAGAAGATTAACCCCATTAGGTTATCAAATAGGGCTAATTGATGAGAAAAGATGG
TGGGCCTATCAAGAAAAAATGAACCTCCTCGAGGAAGAAAAATTAAGATTAAATAACACCCGTTTAAAAAATACCGATGA
AATATCAAAAAACATAGAATTAGACACGGGATCAAAGATCAAAGGCTCAACAACTTTGAAAGAACTCTTAAAAAGACCAA
ACTTTCATTATTCAGATCTAATTAAATATAATTTGACTGAAAAAAATCTAGGTTCTTCAATACAGGAAGGTGTTGAAATA
GATATTAAATACGAGGGTTACCTTAAAAGACAAAAAAACAACATTGAACAAATAAATCGTCAAAGCTGTAAATCTCTACC
TCAAGAAATAAATTATGAAAAGATAGATACATTATCTTTAGAAGCTAGAGAAAATTTGAATAAGATAAAACCAAAAAATT
TTGGTGATGCTTCAAAAATTCCTGGAGTAAGCAAAGCTGATTTAACTGCATTACTTGTTTGGCTAAAAATAAGAGAAATA
AAGAAAGAAAAGGCAAATATTTTTGTCAAAAAAAGTTATCATCTTAAAAGTAATCCGTCAGAGCACTGA

Upstream 100 bases:

>100_bases
GTCACTAAACATAGAAATGGACCCGTAGGAACTGTTAAATTATTATTTGAACCTCAATTTACGAGATTTAGAAATTTAGC
TAATTAAATCGATCCGAATA

Downstream 100 bases:

>100_bases
ATAATAAACTTTTTAACTCACCAAAAATTTTATGGGAAGAAAAAGCCTCTACTTTTTTAGTGAAAAATTCATTACCAAAA
ATATCAGGTCCATGGAAATT

Product: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA

Products: NA

Alternate protein names: Glucose-inhibited division protein A

Number of amino acids: Translated: 662; Mature: 662

Protein sequence:

>662_residues
MQDHHSTNESFDIVVIGGGHAGCEAAITSAKLGFSTALFTINLDRIAWQPCNPAVGGPAKSQLVHEVDALGGIIGKLADK
TAIQKRILNASKGPAVWALRAQTDKREYSKKMIEILQNTDNLSLKEAMITELDIAKTEEIGLNSKKIVKKRIKGVRTFFG
SYYSARSVIITAGTFLEGRIWIGNKSMSAGRSGEQAAKGLTKNLHEIGIKTERLKTGTPARVDKRSIIFDELDAQPSTAA
DKYFSFDPNIKNNMPQVSCHITRTTTKTHQLIRDNLHLTPIYGGFIDSKGPRYCPSIEDKIVKFADKESHQIFLEPEGIN
TPEIYVQGFSTGLPENIQLELLRTLPGLSECKMLRPAYAVEYDYIPATQLQTSLETKEIEYLFSAGQINGTTGYEEAAAQ
GLVAGVNATRKLNEKDPIIFTRESSYIGTMINDLITKDLKEPYRVLTSRSEYRLTLRGDNADRRLTPLGYQIGLIDEKRW
WAYQEKMNLLEEEKLRLNNTRLKNTDEISKNIELDTGSKIKGSTTLKELLKRPNFHYSDLIKYNLTEKNLGSSIQEGVEI
DIKYEGYLKRQKNNIEQINRQSCKSLPQEINYEKIDTLSLEARENLNKIKPKNFGDASKIPGVSKADLTALLVWLKIREI
KKEKANIFVKKSYHLKSNPSEH

Sequences:

>Translated_662_residues
MQDHHSTNESFDIVVIGGGHAGCEAAITSAKLGFSTALFTINLDRIAWQPCNPAVGGPAKSQLVHEVDALGGIIGKLADK
TAIQKRILNASKGPAVWALRAQTDKREYSKKMIEILQNTDNLSLKEAMITELDIAKTEEIGLNSKKIVKKRIKGVRTFFG
SYYSARSVIITAGTFLEGRIWIGNKSMSAGRSGEQAAKGLTKNLHEIGIKTERLKTGTPARVDKRSIIFDELDAQPSTAA
DKYFSFDPNIKNNMPQVSCHITRTTTKTHQLIRDNLHLTPIYGGFIDSKGPRYCPSIEDKIVKFADKESHQIFLEPEGIN
TPEIYVQGFSTGLPENIQLELLRTLPGLSECKMLRPAYAVEYDYIPATQLQTSLETKEIEYLFSAGQINGTTGYEEAAAQ
GLVAGVNATRKLNEKDPIIFTRESSYIGTMINDLITKDLKEPYRVLTSRSEYRLTLRGDNADRRLTPLGYQIGLIDEKRW
WAYQEKMNLLEEEKLRLNNTRLKNTDEISKNIELDTGSKIKGSTTLKELLKRPNFHYSDLIKYNLTEKNLGSSIQEGVEI
DIKYEGYLKRQKNNIEQINRQSCKSLPQEINYEKIDTLSLEARENLNKIKPKNFGDASKIPGVSKADLTALLVWLKIREI
KKEKANIFVKKSYHLKSNPSEH
>Mature_662_residues
MQDHHSTNESFDIVVIGGGHAGCEAAITSAKLGFSTALFTINLDRIAWQPCNPAVGGPAKSQLVHEVDALGGIIGKLADK
TAIQKRILNASKGPAVWALRAQTDKREYSKKMIEILQNTDNLSLKEAMITELDIAKTEEIGLNSKKIVKKRIKGVRTFFG
SYYSARSVIITAGTFLEGRIWIGNKSMSAGRSGEQAAKGLTKNLHEIGIKTERLKTGTPARVDKRSIIFDELDAQPSTAA
DKYFSFDPNIKNNMPQVSCHITRTTTKTHQLIRDNLHLTPIYGGFIDSKGPRYCPSIEDKIVKFADKESHQIFLEPEGIN
TPEIYVQGFSTGLPENIQLELLRTLPGLSECKMLRPAYAVEYDYIPATQLQTSLETKEIEYLFSAGQINGTTGYEEAAAQ
GLVAGVNATRKLNEKDPIIFTRESSYIGTMINDLITKDLKEPYRVLTSRSEYRLTLRGDNADRRLTPLGYQIGLIDEKRW
WAYQEKMNLLEEEKLRLNNTRLKNTDEISKNIELDTGSKIKGSTTLKELLKRPNFHYSDLIKYNLTEKNLGSSIQEGVEI
DIKYEGYLKRQKNNIEQINRQSCKSLPQEINYEKIDTLSLEARENLNKIKPKNFGDASKIPGVSKADLTALLVWLKIREI
KKEKANIFVKKSYHLKSNPSEH

Specific function: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34

COG id: COG0445

COG function: function code D; NAD/FAD-utilizing enzyme apparently involved in cell division

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MnmG family

Homologues:

Organism=Homo sapiens, GI74024895, Length=648, Percent_Identity=38.4259259259259, Blast_Score=412, Evalue=1e-115,
Organism=Homo sapiens, GI19882217, Length=673, Percent_Identity=36.998514115899, Blast_Score=398, Evalue=1e-110,
Organism=Homo sapiens, GI183227703, Length=688, Percent_Identity=36.1918604651163, Blast_Score=392, Evalue=1e-109,
Organism=Escherichia coli, GI2367273, Length=638, Percent_Identity=43.4169278996865, Blast_Score=536, Evalue=1e-153,
Organism=Caenorhabditis elegans, GI17534255, Length=634, Percent_Identity=36.5930599369085, Blast_Score=397, Evalue=1e-110,
Organism=Saccharomyces cerevisiae, GI6321202, Length=629, Percent_Identity=41.0174880763116, Blast_Score=452, Evalue=1e-128,
Organism=Drosophila melanogaster, GI24658174, Length=659, Percent_Identity=37.9362670713202, Blast_Score=395, Evalue=1e-110,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MNMG_PROM9 (Q317W7)

Other databases:

- EMBL:   CP000111
- RefSeq:   YP_398264.1
- ProteinModelPortal:   Q317W7
- SMR:   Q317W7
- STRING:   Q317W7
- GeneID:   3766593
- GenomeReviews:   CP000111_GR
- KEGG:   pmi:PMT9312_1767
- eggNOG:   COG0445
- HOGENOM:   HBG284774
- OMA:   GIQFRVL
- ProtClustDB:   PRK05192
- BioCyc:   PMAR74546:PMT9312_1767-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00129
- InterPro:   IPR004416
- InterPro:   IPR002218
- InterPro:   IPR020595
- TIGRFAMs:   TIGR00136

Pfam domain/function: PF01134 GIDA

EC number: NA

Molecular weight: Translated: 74421; Mature: 74421

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: PS01280 GIDA_1; PS01281 GIDA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDHHSTNESFDIVVIGGGHAGCEAAITSAKLGFSTALFTINLDRIAWQPCNPAVGGPAK
CCCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCEEEEEEEEEHHEEECCCCCCCCCCHH
SQLVHEVDALGGIIGKLADKTAIQKRILNASKGPAVWALRAQTDKREYSKKMIEILQNTD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCC
NLSLKEAMITELDIAKTEEIGLNSKKIVKKRIKGVRTFFGSYYSARSVIITAGTFLEGRI
CCCHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCEEEEEE
WIGNKSMSAGRSGEQAAKGLTKNLHEIGIKTERLKTGTPARVDKRSIIFDELDAQPSTAA
EECCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCEEHHHCCCCCCCCH
DKYFSFDPNIKNNMPQVSCHITRTTTKTHQLIRDNLHLTPIYGGFIDSKGPRYCPSIEDK
HCEEECCCCCCCCCCEEEEEEEECCHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHH
IVKFADKESHQIFLEPEGINTPEIYVQGFSTGLPENIQLELLRTLPGLSECKMLRPAYAV
HHHHCCCCCCEEEECCCCCCCCEEEEEECCCCCCCCHHHHHHHHCCCHHHHHHCCCHHEE
EYDYIPATQLQTSLETKEIEYLFSAGQINGTTGYEEAAAQGLVAGVNATRKLNEKDPIIF
EECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCHHHCCCCCCCEEE
TRESSYIGTMINDLITKDLKEPYRVLTSRSEYRLTLRGDNADRRLTPLGYQIGLIDEKRW
EECCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEECCCCEEEEEECCHHH
WAYQEKMNLLEEEKLRLNNTRLKNTDEISKNIELDTGSKIKGSTTLKELLKRPNFHYSDL
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCEECCCCCCCCCCHHHHHHHHCCCCCHHHH
IKYNLTEKNLGSSIQEGVEIDIKYEGYLKRQKNNIEQINRQSCKSLPQEINYEKIDTLSL
EEECCCHHHCCHHHHCCCEEEEEECCHHHHHHCCHHHHHHHHHHHHHHHCCCCHHCEEEH
EARENLNKIKPKNFGDASKIPGVSKADLTALLVWLKIREIKKEKANIFVKKSYHLKSNPS
HHHHHHHHCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCC
EH
CC
>Mature Secondary Structure
MQDHHSTNESFDIVVIGGGHAGCEAAITSAKLGFSTALFTINLDRIAWQPCNPAVGGPAK
CCCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCEEEEEEEEEHHEEECCCCCCCCCCHH
SQLVHEVDALGGIIGKLADKTAIQKRILNASKGPAVWALRAQTDKREYSKKMIEILQNTD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCC
NLSLKEAMITELDIAKTEEIGLNSKKIVKKRIKGVRTFFGSYYSARSVIITAGTFLEGRI
CCCHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCEEEEEE
WIGNKSMSAGRSGEQAAKGLTKNLHEIGIKTERLKTGTPARVDKRSIIFDELDAQPSTAA
EECCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCEEHHHCCCCCCCCH
DKYFSFDPNIKNNMPQVSCHITRTTTKTHQLIRDNLHLTPIYGGFIDSKGPRYCPSIEDK
HCEEECCCCCCCCCCEEEEEEEECCHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHH
IVKFADKESHQIFLEPEGINTPEIYVQGFSTGLPENIQLELLRTLPGLSECKMLRPAYAV
HHHHCCCCCCEEEECCCCCCCCEEEEEECCCCCCCCHHHHHHHHCCCHHHHHHCCCHHEE
EYDYIPATQLQTSLETKEIEYLFSAGQINGTTGYEEAAAQGLVAGVNATRKLNEKDPIIF
EECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCHHHCCCCCCCEEE
TRESSYIGTMINDLITKDLKEPYRVLTSRSEYRLTLRGDNADRRLTPLGYQIGLIDEKRW
EECCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEECCCCEEEEEECCHHH
WAYQEKMNLLEEEKLRLNNTRLKNTDEISKNIELDTGSKIKGSTTLKELLKRPNFHYSDL
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCEECCCCCCCCCCHHHHHHHHCCCCCHHHH
IKYNLTEKNLGSSIQEGVEIDIKYEGYLKRQKNNIEQINRQSCKSLPQEINYEKIDTLSL
EEECCCHHHCCHHHHCCCEEEEEECCHHHHHHCCHHHHHHHHHHHHHHHCCCCHHCEEEH
EARENLNKIKPKNFGDASKIPGVSKADLTALLVWLKIREIKKEKANIFVKKSYHLKSNPS
HHHHHHHHCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCC
EH
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA