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The map label for this gene is mrdB [H]

Identifier: 78780057

GI number: 78780057

Start: 1561523

End: 1562791

Strand: Reverse

Name: mrdB [H]

Synonym: PMT9312_1672

Alternate gene names: 78780057

Gene position: 1562791-1561523 (Counterclockwise)

Preceding gene: 78780058

Following gene: 78780056

Centisome position: 91.43

GC content: 29.71

Gene sequence:

>1269_bases
ATGTTTAGGAGAATTTCTTTATTAAATAACAGAGGATTTTTACAAAAAAAAGATAACTTTAATAGAGGTTTTTTATTTTC
TCCAATACTTATAATTCCTCTGTTTTTAGTTATTATTTCGGGTTTATTAATAAAAAGTATTCAGGGTGATTTTTTAGTAT
CGAACTATTTAGGTCATATCCTAACTGGTTTTTTAGGTTATTTTTTAGCATTTTTTATTTCTTATATACCGTTAGAGAGA
ATTAGAAAGTATTTGGTTCCATTTTATTTTTGTACTTTAATATCCTTATTACTAATTTATTTTTTTGGGATTTCAGTTTC
TGGAGCTCAAAGATGGCTAAACTTTGGCATCTTTTCTTTTCAGCCTTCAGAAGTAGCTAAACTTAGTACTGTGTTAACTC
TTGCTTTAGTACTCGACAAAAAAATAATTTTAACAATAAGAGATTTAGTATTGCCCTTATTAGTAGTAGTTATTCCTTGG
TTATTAATTTTCTTTCAACCGGACTTAGGTACCTCTTTAGTTTTACTTGTTTTGACAGGTGTGATGCTCTATTGGTCGCA
TATGCCCATAGAGTGGATTTTGATATTAGTGTTTTGTATTATCACTGCTGCATTTTATCTAACCTTACCAACTCTTCTTA
TTTTCTGGATTCCATTTATAGGATATCTTGCTTATAGATCTTCGAAAAAGAAAATTATTTTTTCTGCTCTCGCTATTTCG
TTACATTTATTAGTGGCAAAATTGACACCAATTTTGTGGCAATATGGCTTAAAAGAATATCAAAAAGATAGATTAGTTTT
ATTTTTAGATCCAAATAGAGATCCATTAGGTGGCGGATATCATTTGATACAGAGTCAAATTGCAATTGGTTCTGGAGGAT
TATTTGGGACGGGTTTGCTACAAGGTAAGCTGACTAATTTGCAATTTATACCGGAACAACATACTGATTTTATATTCAGT
GCTCTAGGCGAAGAATTGGGTTTTGTAGGGTGCATGATAGTTTTATTTTTGTTCTTTTTTTTGATTAAAAAACTTATTAA
TACTGCAACAATTGCTAGGACTAATTTTGAATCTCTAATTGTTATTGGAATAGCCTCAACTTTTTTATTTCAAATAATAA
TTAACTTATTTATGACTATTGGATTAGGACCAGTGACTGGGATTCCCCTTCCTTTTATGAGCTATGGTCGAACGTCATTG
GTGACTAATTTTATATCTATTGGATTTGTTTTATCTATATTGAAACGTTCTAGATCACTAAGAAATTGA

Upstream 100 bases:

>100_bases
AGGTATACCAATCTCAATAAGCCAACCCAATAAAGAAAGTTCTGTTGTATTTAGTAATTTAGCTCAATTAATTAAGAATC
AATTCGTTAATAGTTAATTG

Downstream 100 bases:

>100_bases
TGAAATCACAAATAACTATAAAAAAAATTCAAGACCTTTTGATTAAAGGAGTTCAAACTATACATGTGGATGATGATTCA
TCCAGAAGAATGTGGTGGGC

Product: rod shape determining protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MFRRISLLNNRGFLQKKDNFNRGFLFSPILIIPLFLVIISGLLIKSIQGDFLVSNYLGHILTGFLGYFLAFFISYIPLER
IRKYLVPFYFCTLISLLLIYFFGISVSGAQRWLNFGIFSFQPSEVAKLSTVLTLALVLDKKIILTIRDLVLPLLVVVIPW
LLIFFQPDLGTSLVLLVLTGVMLYWSHMPIEWILILVFCIITAAFYLTLPTLLIFWIPFIGYLAYRSSKKKIIFSALAIS
LHLLVAKLTPILWQYGLKEYQKDRLVLFLDPNRDPLGGGYHLIQSQIAIGSGGLFGTGLLQGKLTNLQFIPEQHTDFIFS
ALGEELGFVGCMIVLFLFFFLIKKLINTATIARTNFESLIVIGIASTFLFQIIINLFMTIGLGPVTGIPLPFMSYGRTSL
VTNFISIGFVLSILKRSRSLRN

Sequences:

>Translated_422_residues
MFRRISLLNNRGFLQKKDNFNRGFLFSPILIIPLFLVIISGLLIKSIQGDFLVSNYLGHILTGFLGYFLAFFISYIPLER
IRKYLVPFYFCTLISLLLIYFFGISVSGAQRWLNFGIFSFQPSEVAKLSTVLTLALVLDKKIILTIRDLVLPLLVVVIPW
LLIFFQPDLGTSLVLLVLTGVMLYWSHMPIEWILILVFCIITAAFYLTLPTLLIFWIPFIGYLAYRSSKKKIIFSALAIS
LHLLVAKLTPILWQYGLKEYQKDRLVLFLDPNRDPLGGGYHLIQSQIAIGSGGLFGTGLLQGKLTNLQFIPEQHTDFIFS
ALGEELGFVGCMIVLFLFFFLIKKLINTATIARTNFESLIVIGIASTFLFQIIINLFMTIGLGPVTGIPLPFMSYGRTSL
VTNFISIGFVLSILKRSRSLRN
>Mature_422_residues
MFRRISLLNNRGFLQKKDNFNRGFLFSPILIIPLFLVIISGLLIKSIQGDFLVSNYLGHILTGFLGYFLAFFISYIPLER
IRKYLVPFYFCTLISLLLIYFFGISVSGAQRWLNFGIFSFQPSEVAKLSTVLTLALVLDKKIILTIRDLVLPLLVVVIPW
LLIFFQPDLGTSLVLLVLTGVMLYWSHMPIEWILILVFCIITAAFYLTLPTLLIFWIPFIGYLAYRSSKKKIIFSALAIS
LHLLVAKLTPILWQYGLKEYQKDRLVLFLDPNRDPLGGGYHLIQSQIAIGSGGLFGTGLLQGKLTNLQFIPEQHTDFIFS
ALGEELGFVGCMIVLFLFFFLIKKLINTATIARTNFESLIVIGIASTFLFQIIINLFMTIGLGPVTGIPLPFMSYGRTSL
VTNFISIGFVLSILKRSRSLRN

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=416, Percent_Identity=33.4134615384615, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI1786277, Length=360, Percent_Identity=28.8888888888889, Blast_Score=141, Evalue=6e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 47773; Mature: 47773

Theoretical pI: Translated: 10.25; Mature: 10.25

Prosite motif: PS00012 PHOSPHOPANTETHEINE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CC
>Mature Secondary Structure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CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]