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The map label for this gene is fabG [C]

Identifier: 78779843

GI number: 78779843

Start: 1369920

End: 1370849

Strand: Direct

Name: fabG [C]

Synonym: PMT9312_1459

Alternate gene names: 78779843

Gene position: 1369920-1370849 (Clockwise)

Preceding gene: 78779840

Following gene: 78779845

Centisome position: 80.15

GC content: 34.84

Gene sequence:

>930_bases
ATGACTGCCACTATTTCTAGACCTACGATTTCTAATTGGGAAACATCTGATATTCCTAATCTTAATGGAAAAACTGCACT
TATTACTGGTGCAAATAGTGGCCTTGGATATTACACGGCAAAGGCCTTAGCCGAAAAAAATGCCCATGTAATCCTGGCAT
GTAGATCACTTGAAAAAGCTAATAAATCTATTCAAAAGCTTAGAGCTTCAAATCCTGAAGGAATATTTTCTCCACTTGAA
TTAGATTTATCAGATTTAAATAATGTTGTTGAAATTCAACCCAAAATTTTTGATGATTTTGAAAATCTGGATTTACTAAT
CAATAATGCAGGCATAATGCACCCGCCTAAAACACTTAGTGCTCAGGGATATGAAATACAATTTGCAGTTAATCATTTAG
CTCATATGCTTTTGACCCTAAAGCTTCTTCCAATTATTGAAAAAAAAGAGGAGTCGAGAATAGTAACGGTTACTTCTGGT
GCACAATTTTTTGGCAAAGTTGGCTGGAAAAATCTGAAAGCAGAGAACTATTACAACAAATGGGAATCTTACTCCAATAG
CAAATTGGCAAATGTAATGTTCGCATTGGAACTAAATGAAAACTTAAAGCCCAAAAATATACTTTCTTTAGCTGCTCACC
CAGGGATAGCAAAAACAAATCTTTTTACTGCTCAAAAACCTAAACCTAGTCCAATCGAAACATTCTCCATGGAATTATTT
AGCCCTATTTTTCAATCCGCTGAGATGGGTGCCTTACCTCAACTTTTTGCAGCTACTTCTCCAGAGGCAAGAGGCGGAGA
TCATTATGGTCCTAAATTTAATTTCAGAGGTTATCCAAAACTATCGCCTACTTCTCCTGTTGCCATTAATAAAAAAGAAA
GAAAAAATTTATGGGAAAAAAGCCTTCAAATACTGAGTAATTTCTTATAA

Upstream 100 bases:

>100_bases
TTAGAGGTTAAATTTAGCTCACGATACTGAATTCAATTATTTACAGTAATTAGGTAATTAAGTTTTAATTAAATCTCTAA
ACAATTTGCAGGATTACTAA

Downstream 100 bases:

>100_bases
ATTTTTCATTTTTACTAACTTTAGAAAATACTTCAATATATGTAACTCACTCTCTGAGAGTTTCATAAATTCTATTAAGA
CATCATAATTTTTTTCATCA

Product: short-chain dehydrogenase/reductase

Products: protochlorophyllide; NADPH; H+

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MTATISRPTISNWETSDIPNLNGKTALITGANSGLGYYTAKALAEKNAHVILACRSLEKANKSIQKLRASNPEGIFSPLE
LDLSDLNNVVEIQPKIFDDFENLDLLINNAGIMHPPKTLSAQGYEIQFAVNHLAHMLLTLKLLPIIEKKEESRIVTVTSG
AQFFGKVGWKNLKAENYYNKWESYSNSKLANVMFALELNENLKPKNILSLAAHPGIAKTNLFTAQKPKPSPIETFSMELF
SPIFQSAEMGALPQLFAATSPEARGGDHYGPKFNFRGYPKLSPTSPVAINKKERKNLWEKSLQILSNFL

Sequences:

>Translated_309_residues
MTATISRPTISNWETSDIPNLNGKTALITGANSGLGYYTAKALAEKNAHVILACRSLEKANKSIQKLRASNPEGIFSPLE
LDLSDLNNVVEIQPKIFDDFENLDLLINNAGIMHPPKTLSAQGYEIQFAVNHLAHMLLTLKLLPIIEKKEESRIVTVTSG
AQFFGKVGWKNLKAENYYNKWESYSNSKLANVMFALELNENLKPKNILSLAAHPGIAKTNLFTAQKPKPSPIETFSMELF
SPIFQSAEMGALPQLFAATSPEARGGDHYGPKFNFRGYPKLSPTSPVAINKKERKNLWEKSLQILSNFL
>Mature_308_residues
TATISRPTISNWETSDIPNLNGKTALITGANSGLGYYTAKALAEKNAHVILACRSLEKANKSIQKLRASNPEGIFSPLEL
DLSDLNNVVEIQPKIFDDFENLDLLINNAGIMHPPKTLSAQGYEIQFAVNHLAHMLLTLKLLPIIEKKEESRIVTVTSGA
QFFGKVGWKNLKAENYYNKWESYSNSKLANVMFALELNENLKPKNILSLAAHPGIAKTNLFTAQKPKPSPIETFSMELFS
PIFQSAEMGALPQLFAATSPEARGGDHYGPKFNFRGYPKLSPTSPVAINKKERKNLWEKSLQILSNFL

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI225579078, Length=289, Percent_Identity=34.9480968858132, Blast_Score=154, Evalue=7e-38,
Organism=Homo sapiens, GI166795268, Length=307, Percent_Identity=32.2475570032573, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI186928839, Length=304, Percent_Identity=32.2368421052632, Blast_Score=152, Evalue=3e-37,
Organism=Homo sapiens, GI10190746, Length=314, Percent_Identity=35.031847133758, Blast_Score=149, Evalue=3e-36,
Organism=Homo sapiens, GI7706523, Length=299, Percent_Identity=29.7658862876254, Blast_Score=132, Evalue=3e-31,
Organism=Homo sapiens, GI146231950, Length=212, Percent_Identity=38.6792452830189, Blast_Score=121, Evalue=8e-28,
Organism=Homo sapiens, GI19923931, Length=254, Percent_Identity=32.6771653543307, Blast_Score=114, Evalue=8e-26,
Organism=Homo sapiens, GI193804850, Length=288, Percent_Identity=28.8194444444444, Blast_Score=107, Evalue=1e-23,
Organism=Escherichia coli, GI1787335, Length=207, Percent_Identity=26.0869565217391, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17558006, Length=295, Percent_Identity=28.135593220339, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17532791, Length=307, Percent_Identity=28.9902280130293, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17532805, Length=310, Percent_Identity=28.3870967741935, Blast_Score=111, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI193207620, Length=306, Percent_Identity=29.0849673202614, Blast_Score=111, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17505416, Length=213, Percent_Identity=31.924882629108, Blast_Score=104, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI71992402, Length=254, Percent_Identity=28.740157480315, Blast_Score=100, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI72001364, Length=293, Percent_Identity=28.3276450511945, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17535059, Length=253, Percent_Identity=28.8537549407115, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI32565532, Length=208, Percent_Identity=29.8076923076923, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17508895, Length=177, Percent_Identity=31.0734463276836, Blast_Score=71, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI115533174, Length=299, Percent_Identity=27.4247491638796, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115533172, Length=296, Percent_Identity=27.027027027027, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17558996, Length=218, Percent_Identity=27.9816513761468, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6324820, Length=320, Percent_Identity=28.75, Blast_Score=109, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6322227, Length=263, Percent_Identity=22.8136882129278, Blast_Score=65, Evalue=9e-12,
Organism=Drosophila melanogaster, GI22024069, Length=291, Percent_Identity=36.426116838488, Blast_Score=144, Evalue=5e-35,
Organism=Drosophila melanogaster, GI45554248, Length=289, Percent_Identity=33.2179930795848, Blast_Score=142, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24640117, Length=289, Percent_Identity=33.2179930795848, Blast_Score=142, Evalue=2e-34,
Organism=Drosophila melanogaster, GI28573296, Length=247, Percent_Identity=36.4372469635627, Blast_Score=142, Evalue=3e-34,
Organism=Drosophila melanogaster, GI19921754, Length=281, Percent_Identity=35.9430604982206, Blast_Score=142, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24586328, Length=294, Percent_Identity=31.6326530612245, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI20129347, Length=255, Percent_Identity=32.156862745098, Blast_Score=130, Evalue=8e-31,
Organism=Drosophila melanogaster, GI161076371, Length=245, Percent_Identity=33.0612244897959, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24656154, Length=256, Percent_Identity=34.375, Blast_Score=115, Evalue=3e-26,
Organism=Drosophila melanogaster, GI19922628, Length=256, Percent_Identity=34.375, Blast_Score=115, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24647946, Length=288, Percent_Identity=29.5138888888889, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI45553409, Length=286, Percent_Identity=30.0699300699301, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24647948, Length=286, Percent_Identity=30.0699300699301, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24647931, Length=307, Percent_Identity=25.0814332247557, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21358495, Length=206, Percent_Identity=29.6116504854369, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24643142, Length=204, Percent_Identity=31.8627450980392, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.3.1.33

Molecular weight: Translated: 34276; Mature: 34145

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATISRPTISNWETSDIPNLNGKTALITGANSGLGYYTAKALAEKNAHVILACRSLEKA
CCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCEEEEEEHHHHHH
NKSIQKLRASNPEGIFSPLELDLSDLNNVVEIQPKIFDDFENLDLLINNAGIMHPPKTLS
HHHHHHHHCCCCCCCCCCCEECHHHCCCEEEECCHHHCCCCCCEEEEECCCCCCCCCCCC
AQGYEIQFAVNHLAHMLLTLKLLPIIEKKEESRIVTVTSGAQFFGKVGWKNLKAENYYNK
CCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHCCCCCCCCHHHHHH
WESYSNSKLANVMFALELNENLKPKNILSLAAHPGIAKTNLFTAQKPKPSPIETFSMELF
HHHCCCCCCEEEEEEEEECCCCCHHHHHHHHCCCCCCCCCEEECCCCCCCCHHHHHHHHH
SPIFQSAEMGALPQLFAATSPEARGGDHYGPKFNFRGYPKLSPTSPVAINKKERKNLWEK
HHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECHHHHHHHHHH
SLQILSNFL
HHHHHHHCC
>Mature Secondary Structure 
TATISRPTISNWETSDIPNLNGKTALITGANSGLGYYTAKALAEKNAHVILACRSLEKA
CCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCEEEEEEHHHHHH
NKSIQKLRASNPEGIFSPLELDLSDLNNVVEIQPKIFDDFENLDLLINNAGIMHPPKTLS
HHHHHHHHCCCCCCCCCCCEECHHHCCCEEEECCHHHCCCCCCEEEEECCCCCCCCCCCC
AQGYEIQFAVNHLAHMLLTLKLLPIIEKKEESRIVTVTSGAQFFGKVGWKNLKAENYYNK
CCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHCCCCCCCCHHHHHH
WESYSNSKLANVMFALELNENLKPKNILSLAAHPGIAKTNLFTAQKPKPSPIETFSMELF
HHHCCCCCCEEEEEEEEECCCCCHHHHHHHHCCCCCCCCCEEECCCCCCCCHHHHHHHHH
SPIFQSAEMGALPQLFAATSPEARGGDHYGPKFNFRGYPKLSPTSPVAINKKERKNLWEK
HHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECHHHHHHHHHH
SLQILSNFL
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: chlorophyllide a; NADP+

Specific reaction: chlorophyllide a + NADP+ = protochlorophyllide + NADPH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8383668 [H]