Click here to switch to the map view.

The map label for this gene is cyaD [H]

Identifier: 78779566

GI number: 78779566

Start: 1101022

End: 1101975

Strand: Direct

Name: cyaD [H]

Synonym: PMT9312_1183

Alternate gene names: 78779566

Gene position: 1101022-1101975 (Clockwise)

Preceding gene: 78779565

Following gene: 78779569

Centisome position: 64.42

GC content: 32.18

Gene sequence:

>954_bases
ATGGACTTTGACAACGAAGCAATACTTTATAAGCCAGCCTCACTTTGGATAAGAGGATTAATTTGGGCAATTGTTGGTAG
TTTTAGTTTTGGATTTATATATGCTTGCTTTGCAAGAATGGATGAGGTCGTAATAGCAAAAGGCGAATTACAAGCTTTAG
GAGCTGAAAGGCCAATAAGAGCACCAATATCAGGAATAGTAAGCGAAATTTTTATAAAAGAAGGTGATTCAGTTGAAAAG
GATTCTAAGCTTTTAAGATTTGATAGTAATGTTCTACATGCAAAAAAAGAGGGTCTTGAAGCAAAGTTAGGGGAATTAGA
GTCTAGTATTCAATCAGAAAAGGAGATTCTAAAAGAGATATCAATTCTTGCTGATGCTGGGGGGATTCAAAAACTTCAAT
ACTTACAACAAAAAAATAAAGTAAGCGAACTAGGTTATGAAAAAAAACAAGTAGAAGCCGAAATTAAGGAGCTAAATTTT
GATAAATCAAAAACACTTTTAGTTTCACCAGTAAAAGGAAAAGTTTTTAATCTGATTTCAGTAAGTAAAGGATTTGCAGC
TAATCAAGGCGAAACACTTTTAAAAATAGTTCCAAGTGGGGACACCGAAGCAAAAATATTTCTCAAAAACTCAGATATTG
GTTTCGTTAAAAGTAATATGAAAGCAAAAATAAGAGTAGATGCATTTCCCTTTACCCAATTTGGTTCAATTGAGGGTATT
CTTAAATCTATTGGTGATGAAGTCATTCGTTCAAATCAACAGAATCAAAGTTCTCTTTTCCCCGCCTATGTAAGTTTAGA
AAAACAGTATCTTGAAAAAAATGGTGAGAAATTTTTTGTTAGATCTGGTCAAAGTGTTTCTGTTAATTTAATTGTTAGAG
ATAAAAGAATAATAAGTCTTTTAACTGATGCTATAGATAAAGCTATTGATTCGCTGAGGGGCATTAAAAGTTAA

Upstream 100 bases:

>100_bases
GGTAATCATGAAAATTTAATGAAGGAGAATGGGAAATATGCTGCATTAATTAAAAAAAAATATACATAAAAAGAGATAAA
TTCAACGATTAAATTTGGAA

Downstream 100 bases:

>100_bases
ATTTCTAATTTAGAAATAAGCATTTTGATAATCTCTAATAATAAAGTTGTTAATATTATCTTTAACTTCTATATGACTAT
AGTTACCTACTCCATCAAAA

Product: leukotoxin secretion protein-like

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MDFDNEAILYKPASLWIRGLIWAIVGSFSFGFIYACFARMDEVVIAKGELQALGAERPIRAPISGIVSEIFIKEGDSVEK
DSKLLRFDSNVLHAKKEGLEAKLGELESSIQSEKEILKEISILADAGGIQKLQYLQQKNKVSELGYEKKQVEAEIKELNF
DKSKTLLVSPVKGKVFNLISVSKGFAANQGETLLKIVPSGDTEAKIFLKNSDIGFVKSNMKAKIRVDAFPFTQFGSIEGI
LKSIGDEVIRSNQQNQSSLFPAYVSLEKQYLEKNGEKFFVRSGQSVSVNLIVRDKRIISLLTDAIDKAIDSLRGIKS

Sequences:

>Translated_317_residues
MDFDNEAILYKPASLWIRGLIWAIVGSFSFGFIYACFARMDEVVIAKGELQALGAERPIRAPISGIVSEIFIKEGDSVEK
DSKLLRFDSNVLHAKKEGLEAKLGELESSIQSEKEILKEISILADAGGIQKLQYLQQKNKVSELGYEKKQVEAEIKELNF
DKSKTLLVSPVKGKVFNLISVSKGFAANQGETLLKIVPSGDTEAKIFLKNSDIGFVKSNMKAKIRVDAFPFTQFGSIEGI
LKSIGDEVIRSNQQNQSSLFPAYVSLEKQYLEKNGEKFFVRSGQSVSVNLIVRDKRIISLLTDAIDKAIDSLRGIKS
>Mature_317_residues
MDFDNEAILYKPASLWIRGLIWAIVGSFSFGFIYACFARMDEVVIAKGELQALGAERPIRAPISGIVSEIFIKEGDSVEK
DSKLLRFDSNVLHAKKEGLEAKLGELESSIQSEKEILKEISILADAGGIQKLQYLQQKNKVSELGYEKKQVEAEIKELNF
DKSKTLLVSPVKGKVFNLISVSKGFAANQGETLLKIVPSGDTEAKIFLKNSDIGFVKSNMKAKIRVDAFPFTQFGSIEGI
LKSIGDEVIRSNQQNQSSLFPAYVSLEKQYLEKNGEKFFVRSGQSVSVNLIVRDKRIISLLTDAIDKAIDSLRGIKS

Specific function: CyaD is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 35149; Mature: 35149

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFDNEAILYKPASLWIRGLIWAIVGSFSFGFIYACFARMDEVVIAKGELQALGAERPIR
CCCCCCEEEECCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHEEEECCHHHHCCCCCCCC
APISGIVSEIFIKEGDSVEKDSKLLRFDSNVLHAKKEGLEAKLGELESSIQSEKEILKEI
CHHHHHHHHHHHCCCCCCCCCCHHHHCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
SILADAGGIQKLQYLQQKNKVSELGYEKKQVEAEIKELNFDKSKTLLVSPVKGKVFNLIS
HHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHH
VSKGFAANQGETLLKIVPSGDTEAKIFLKNSDIGFVKSNMKAKIRVDAFPFTQFGSIEGI
HCCCCCCCCCCEEEEEECCCCCCEEEEEECCCCCEEECCCEEEEEEEECCCCCCCCHHHH
LKSIGDEVIRSNQQNQSSLFPAYVSLEKQYLEKNGEKFFVRSGQSVSVNLIVRDKRIISL
HHHHHHHHHHCCCCCCHHHCHHHHHHHHHHHHCCCCEEEEECCCEEEEEEEEECHHHHHH
LTDAIDKAIDSLRGIKS
HHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDFDNEAILYKPASLWIRGLIWAIVGSFSFGFIYACFARMDEVVIAKGELQALGAERPIR
CCCCCCEEEECCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHEEEECCHHHHCCCCCCCC
APISGIVSEIFIKEGDSVEKDSKLLRFDSNVLHAKKEGLEAKLGELESSIQSEKEILKEI
CHHHHHHHHHHHCCCCCCCCCCHHHHCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
SILADAGGIQKLQYLQQKNKVSELGYEKKQVEAEIKELNFDKSKTLLVSPVKGKVFNLIS
HHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHH
VSKGFAANQGETLLKIVPSGDTEAKIFLKNSDIGFVKSNMKAKIRVDAFPFTQFGSIEGI
HCCCCCCCCCCEEEEEECCCCCCEEEEEECCCCCEEECCCEEEEEEEECCCCCCCCHHHH
LKSIGDEVIRSNQQNQSSLFPAYVSLEKQYLEKNGEKFFVRSGQSVSVNLIVRDKRIISL
HHHHHHHHHHCCCCCCHHHCHHHHHHHHHHHHCCCCEEEEECCCEEEEEEEEECHHHHHH
LTDAIDKAIDSLRGIKS
HHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2905265; 12910271 [H]