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The map label for this gene is clpB [H]

Identifier: 78779482

GI number: 78779482

Start: 1011296

End: 1013824

Strand: Reverse

Name: clpB [H]

Synonym: PMT9312_1099

Alternate gene names: 78779482

Gene position: 1013824-1011296 (Counterclockwise)

Preceding gene: 78779483

Following gene: 78779481

Centisome position: 59.32

GC content: 36.3

Gene sequence:

>2529_bases
ATGTTTGAAAGGTTTACAGAAAAGGCTATAAAAGTCATTATGCTTGCCCAAGAGGAAGCGAGAAGACTTGGTCATAATTT
CGTTGGAACAGAACAGATTTTATTAGGTCTAATTGGTGAGGGTACAGGAGTTGCGGCAAAGGTTCTTAAATCACTAGGTG
TCAATTTAAAAGATTCAAGAATAGAAGTAGAAAAAATAATTGGTAGAGGTTCAGGATTTGTAGCTGTAGAAATACCCTTT
ACCCCTAGGGCGAAAAGAGTCTTAGAATTATCTCTTGAAGAAGCGCGTCAATTGGGTCATAATTATATAGGGACTGAACA
TCTTTTACTGGGTTTAATAAGAGAAGGTGAGGGCGTAGCTGCAAGGGTGCTAGAAAATCTAAGTATTGATCTCACTAAAG
TGAGAACTCAAGTCATAAGGATGCTTGGTGAAACAGCTGAAGTCGGAAGTGGAGCTAATTCAAGCAAGGGTAATTTAAAA
ACGGCAACTCTTGATGAATTTGGAACAAATTTAACAAAGCTTGCTAGTGAATCAAAACTCGATCCAGTAGTTGGCCGTTA
TGCAGAAATAGATCGCGTAGTCCAAATATTAGGTAGAAGGACTAAAAATAATCCCGTTCTTATCGGTGAACCTGGCGTAG
GTAAAACTGCTATTGCAGAGGGTTTAGCTCAAAGAATACAGCTAGGAGATATTCCTGACATACTTGAAGATAAAAGAGTT
TTAACTCTTGATATAGGACTCTTGGTCGCTGGAACAAAATATAGAGGAGAATTTGAGGAAAGATTGAAAAAGATAATGGA
AGAAATTAAATCTGCCGGTAATGTAATACTTGTTATAGATGAAGTGCATACTTTAATTGGTGCTGGAGCTGCTGAAGGTG
CTATAGATGCAGCAAATATTCTGAAGCCAGCCTTAGCCCGAGGAGAACTCCAATGTATTGGAGCAACAACACTCGATGAA
TATAGAAAACATATTGAAAGAGATGCCGCTCTAGAGAGAAGATTCCAACCTGTAATGGTTGGTGAACCATCTATTGAAGA
TACGATCGAAATCTTAAAAGGTCTTCGAGAACGTTATGAACAACATCATCGCTTAAAAATTACTGATGAAGCTTTAGAAG
CTGCAGCGCACCTAGGAGATCGATATATATCCGATAGGTTCTTGCCCGATAAAGCTATAGACCTTATCGATGAGGCAGGA
AGTAGAGTACGTTTAATAAACTCTAAACTTCCACCTGAAGCAAAACAAATAGACAAAGAACTGAGACAAATTCAAAAACA
AAAGGAAGAATCTGTCAGAGATCAAAATTTTGATCAAGCTGGCCAATTAAGAGAAAAGGAGATCGAATTATCTGCAAAAA
TTAAAGAGGTTCTTGAAAATAAAAAAGAATCTACAACTGAGGATGAATCTAGTGTTGATACAAACTCAGTAAAAAATGAT
TCAAAACTTTTACAAAACCCTATGGTTAATGAAGAGGACGTAGCACATATTGTTGCATCTTGGACTGGTGTACCTGTTCA
AAAATTAACTGAAACTGAATCAGTCAAGCTACTCAATATGGAGGAAACACTTCACCAAAGGCTAATTGGACAAGATGAAG
CTGTAAAAGCTGTTTCTAGAGCTATCAGAAGAGCAAGAGTTGGTTTAAAAAATCCAAATAGGCCCATCGCAAGTTTTATC
TTTTCAGGACCTACTGGTGTAGGAAAAACTGAATTGACTAAATCATTAGCTTCCTACTTCTTCGGTAGCGAAGAAGCCAT
GATTAGATTAGATATGTCAGAATTTATGGAAAGACATACTGTTAGTAAACTTATAGGTTCCCCTCCGGGATATGTCGGTT
TTAATGAAGGTGGTCAACTTACTGAGGCGGTTAGAAGAAGACCTTATACCGTTGTTTTATTTGATGAAGTAGAGAAAGCT
CATCCAGATGTATTCAATTTGTTATTACAACTTCTTGAGGACGGTAGACTAACAGATTCCAAAGGTAGAACTGTAGATTT
TAAAAATACTTTGCTAATAATGACTTCTAATATTGGTTCAAAAGTGATTGAGAAAGGTGGAGGCGGCTTAGGATTTGAGT
TTTCTGGTGATTCTGTTGAAGATAGTCAATACAATAGAATTAAATCTTTAGTTAATGAAGAACTAAAGCAATACTTCAGA
CCTGAATTTTTAAATAGACTTGATGAAATAATTGTATTCAGGCAACTATCTAAAAACGAGGTTAAAGAAATTGCTGAAAT
TATGTTACAAGAGGTTTTTGCAAGACTAGAAGATAAGGGCATTAAATTAAGCGTAACTGATGCTTTCAAAGAAAGACTTG
TTGAAGAAGGCTATAATCCTTCATATGGAGCACGACCCTTAAGAAGAGCTGTTATGCGATTATTAGAGGATAGTTTGGCT
GAAGAAGTTCTTTCAGGAAGAATAAAAGATGGAGACAAGGCTTTAGTTGATATAGACGATAATAAAAAAGTTACAATCAA
TATTTCTTCTGAAGAGTCTTCTCAAGAGTTAGCAAGTGCTAACTTTTAG

Upstream 100 bases:

>100_bases
TTAATTCAATAAAATATACTTTTGGGTATTCACAAAAGCTCATTCTGAACACAAAATTGACATATTACTGGTAGGTTATT
AGTAGGATTTTAATCTTCTA

Downstream 100 bases:

>100_bases
GCATTAAAACAAATATGCAGTTAATTTCTCCAGAAATTGTATTTAGGGGGAAAGATGCTTGGGAAAAAGCTTTACCTCAA
ATTACTAAATTAACCAAAAG

Product: Clp protease ATP-binding subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 842; Mature: 842

Protein sequence:

>842_residues
MFERFTEKAIKVIMLAQEEARRLGHNFVGTEQILLGLIGEGTGVAAKVLKSLGVNLKDSRIEVEKIIGRGSGFVAVEIPF
TPRAKRVLELSLEEARQLGHNYIGTEHLLLGLIREGEGVAARVLENLSIDLTKVRTQVIRMLGETAEVGSGANSSKGNLK
TATLDEFGTNLTKLASESKLDPVVGRYAEIDRVVQILGRRTKNNPVLIGEPGVGKTAIAEGLAQRIQLGDIPDILEDKRV
LTLDIGLLVAGTKYRGEFEERLKKIMEEIKSAGNVILVIDEVHTLIGAGAAEGAIDAANILKPALARGELQCIGATTLDE
YRKHIERDAALERRFQPVMVGEPSIEDTIEILKGLRERYEQHHRLKITDEALEAAAHLGDRYISDRFLPDKAIDLIDEAG
SRVRLINSKLPPEAKQIDKELRQIQKQKEESVRDQNFDQAGQLREKEIELSAKIKEVLENKKESTTEDESSVDTNSVKND
SKLLQNPMVNEEDVAHIVASWTGVPVQKLTETESVKLLNMEETLHQRLIGQDEAVKAVSRAIRRARVGLKNPNRPIASFI
FSGPTGVGKTELTKSLASYFFGSEEAMIRLDMSEFMERHTVSKLIGSPPGYVGFNEGGQLTEAVRRRPYTVVLFDEVEKA
HPDVFNLLLQLLEDGRLTDSKGRTVDFKNTLLIMTSNIGSKVIEKGGGGLGFEFSGDSVEDSQYNRIKSLVNEELKQYFR
PEFLNRLDEIIVFRQLSKNEVKEIAEIMLQEVFARLEDKGIKLSVTDAFKERLVEEGYNPSYGARPLRRAVMRLLEDSLA
EEVLSGRIKDGDKALVDIDDNKKVTINISSEESSQELASANF

Sequences:

>Translated_842_residues
MFERFTEKAIKVIMLAQEEARRLGHNFVGTEQILLGLIGEGTGVAAKVLKSLGVNLKDSRIEVEKIIGRGSGFVAVEIPF
TPRAKRVLELSLEEARQLGHNYIGTEHLLLGLIREGEGVAARVLENLSIDLTKVRTQVIRMLGETAEVGSGANSSKGNLK
TATLDEFGTNLTKLASESKLDPVVGRYAEIDRVVQILGRRTKNNPVLIGEPGVGKTAIAEGLAQRIQLGDIPDILEDKRV
LTLDIGLLVAGTKYRGEFEERLKKIMEEIKSAGNVILVIDEVHTLIGAGAAEGAIDAANILKPALARGELQCIGATTLDE
YRKHIERDAALERRFQPVMVGEPSIEDTIEILKGLRERYEQHHRLKITDEALEAAAHLGDRYISDRFLPDKAIDLIDEAG
SRVRLINSKLPPEAKQIDKELRQIQKQKEESVRDQNFDQAGQLREKEIELSAKIKEVLENKKESTTEDESSVDTNSVKND
SKLLQNPMVNEEDVAHIVASWTGVPVQKLTETESVKLLNMEETLHQRLIGQDEAVKAVSRAIRRARVGLKNPNRPIASFI
FSGPTGVGKTELTKSLASYFFGSEEAMIRLDMSEFMERHTVSKLIGSPPGYVGFNEGGQLTEAVRRRPYTVVLFDEVEKA
HPDVFNLLLQLLEDGRLTDSKGRTVDFKNTLLIMTSNIGSKVIEKGGGGLGFEFSGDSVEDSQYNRIKSLVNEELKQYFR
PEFLNRLDEIIVFRQLSKNEVKEIAEIMLQEVFARLEDKGIKLSVTDAFKERLVEEGYNPSYGARPLRRAVMRLLEDSLA
EEVLSGRIKDGDKALVDIDDNKKVTINISSEESSQELASANF
>Mature_842_residues
MFERFTEKAIKVIMLAQEEARRLGHNFVGTEQILLGLIGEGTGVAAKVLKSLGVNLKDSRIEVEKIIGRGSGFVAVEIPF
TPRAKRVLELSLEEARQLGHNYIGTEHLLLGLIREGEGVAARVLENLSIDLTKVRTQVIRMLGETAEVGSGANSSKGNLK
TATLDEFGTNLTKLASESKLDPVVGRYAEIDRVVQILGRRTKNNPVLIGEPGVGKTAIAEGLAQRIQLGDIPDILEDKRV
LTLDIGLLVAGTKYRGEFEERLKKIMEEIKSAGNVILVIDEVHTLIGAGAAEGAIDAANILKPALARGELQCIGATTLDE
YRKHIERDAALERRFQPVMVGEPSIEDTIEILKGLRERYEQHHRLKITDEALEAAAHLGDRYISDRFLPDKAIDLIDEAG
SRVRLINSKLPPEAKQIDKELRQIQKQKEESVRDQNFDQAGQLREKEIELSAKIKEVLENKKESTTEDESSVDTNSVKND
SKLLQNPMVNEEDVAHIVASWTGVPVQKLTETESVKLLNMEETLHQRLIGQDEAVKAVSRAIRRARVGLKNPNRPIASFI
FSGPTGVGKTELTKSLASYFFGSEEAMIRLDMSEFMERHTVSKLIGSPPGYVGFNEGGQLTEAVRRRPYTVVLFDEVEKA
HPDVFNLLLQLLEDGRLTDSKGRTVDFKNTLLIMTSNIGSKVIEKGGGGLGFEFSGDSVEDSQYNRIKSLVNEELKQYFR
PEFLNRLDEIIVFRQLSKNEVKEIAEIMLQEVFARLEDKGIKLSVTDAFKERLVEEGYNPSYGARPLRRAVMRLLEDSLA
EEVLSGRIKDGDKALVDIDDNKKVTINISSEESSQELASANF

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=324, Percent_Identity=37.962962962963, Blast_Score=204, Evalue=4e-52,
Organism=Escherichia coli, GI1788943, Length=880, Percent_Identity=46.0227272727273, Blast_Score=746, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=823, Percent_Identity=36.9380315917375, Blast_Score=499, Evalue=1e-142,
Organism=Saccharomyces cerevisiae, GI6320464, Length=709, Percent_Identity=48.0959097320169, Blast_Score=635, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=899, Percent_Identity=36.5962180200222, Blast_Score=545, Evalue=1e-155,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150
- InterPro:   IPR001943 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 93574; Mature: 93574

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: PS50151 UVR ; PS00036 BZIP_BASIC ; PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFERFTEKAIKVIMLAQEEARRLGHNFVGTEQILLGLIGEGTGVAAKVLKSLGVNLKDSR
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHH
IEVEKIIGRGSGFVAVEIPFTPRAKRVLELSLEEARQLGHNYIGTEHLLLGLIREGEGVA
HHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHH
ARVLENLSIDLTKVRTQVIRMLGETAEVGSGANSSKGNLKTATLDEFGTNLTKLASESKL
HHHHHHCCCHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCEEEEHHHHCCHHHHHHHHCCC
DPVVGRYAEIDRVVQILGRRTKNNPVLIGEPGVGKTAIAEGLAQRIQLGDIPDILEDKRV
CHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCHHHCCCEE
LTLDIGLLVAGTKYRGEFEERLKKIMEEIKSAGNVILVIDEVHTLIGAGAAEGAIDAANI
EEEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHCCCCCCCCCHHHHH
LKPALARGELQCIGATTLDEYRKHIERDAALERRFQPVMVGEPSIEDTIEILKGLRERYE
HHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHH
QHHRLKITDEALEAAAHLGDRYISDRFLPDKAIDLIDEAGSRVRLINSKLPPEAKQIDKE
HHCCEEECHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEECCCCCCHHHHHHHH
LRQIQKQKEESVRDQNFDQAGQLREKEIELSAKIKEVLENKKESTTEDESSVDTNSVKND
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCH
SKLLQNPMVNEEDVAHIVASWTGVPVQKLTETESVKLLNMEETLHQRLIGQDEAVKAVSR
HHHHHCCCCCHHHHHHHHHHCCCCCHHHHCCCCCEEEECHHHHHHHHHCCCHHHHHHHHH
AIRRARVGLKNPNRPIASFIFSGPTGVGKTELTKSLASYFFGSEEAMIRLDMSEFMERHT
HHHHHHCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHH
VSKLIGSPPGYVGFNEGGQLTEAVRRRPYTVVLFDEVEKAHPDVFNLLLQLLEDGRLTDS
HHHHHCCCCCCCCCCCCCHHHHHHHHCCCEEEEECCHHHHCCHHHHHHHHHHHCCCCCCC
KGRTVDFKNTLLIMTSNIGSKVIEKGGGGLGFEFSGDSVEDSQYNRIKSLVNEELKQYFR
CCCEEEECCEEEEEECCCCHHHHHCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHC
PEFLNRLDEIIVFRQLSKNEVKEIAEIMLQEVFARLEDKGIKLSVTDAFKERLVEEGYNP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCCC
SYGARPLRRAVMRLLEDSLAEEVLSGRIKDGDKALVDIDDNKKVTINISSEESSQELASA
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEEEEECCCCHHHHHHCC
NF
CC
>Mature Secondary Structure
MFERFTEKAIKVIMLAQEEARRLGHNFVGTEQILLGLIGEGTGVAAKVLKSLGVNLKDSR
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHH
IEVEKIIGRGSGFVAVEIPFTPRAKRVLELSLEEARQLGHNYIGTEHLLLGLIREGEGVA
HHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHH
ARVLENLSIDLTKVRTQVIRMLGETAEVGSGANSSKGNLKTATLDEFGTNLTKLASESKL
HHHHHHCCCHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCEEEEHHHHCCHHHHHHHHCCC
DPVVGRYAEIDRVVQILGRRTKNNPVLIGEPGVGKTAIAEGLAQRIQLGDIPDILEDKRV
CHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCHHHCCCEE
LTLDIGLLVAGTKYRGEFEERLKKIMEEIKSAGNVILVIDEVHTLIGAGAAEGAIDAANI
EEEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHCCCCCCCCCHHHHH
LKPALARGELQCIGATTLDEYRKHIERDAALERRFQPVMVGEPSIEDTIEILKGLRERYE
HHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHH
QHHRLKITDEALEAAAHLGDRYISDRFLPDKAIDLIDEAGSRVRLINSKLPPEAKQIDKE
HHCCEEECHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEECCCCCCHHHHHHHH
LRQIQKQKEESVRDQNFDQAGQLREKEIELSAKIKEVLENKKESTTEDESSVDTNSVKND
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCH
SKLLQNPMVNEEDVAHIVASWTGVPVQKLTETESVKLLNMEETLHQRLIGQDEAVKAVSR
HHHHHCCCCCHHHHHHHHHHCCCCCHHHHCCCCCEEEECHHHHHHHHHCCCHHHHHHHHH
AIRRARVGLKNPNRPIASFIFSGPTGVGKTELTKSLASYFFGSEEAMIRLDMSEFMERHT
HHHHHHCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHH
VSKLIGSPPGYVGFNEGGQLTEAVRRRPYTVVLFDEVEKAHPDVFNLLLQLLEDGRLTDS
HHHHHCCCCCCCCCCCCCHHHHHHHHCCCEEEEECCHHHHCCHHHHHHHHHHHCCCCCCC
KGRTVDFKNTLLIMTSNIGSKVIEKGGGGLGFEFSGDSVEDSQYNRIKSLVNEELKQYFR
CCCEEEECCEEEEEECCCCHHHHHCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHC
PEFLNRLDEIIVFRQLSKNEVKEIAEIMLQEVFARLEDKGIKLSVTDAFKERLVEEGYNP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCCC
SYGARPLRRAVMRLLEDSLAEEVLSGRIKDGDKALVDIDDNKKVTINISSEESSQELASA
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEEEEECCCCHHHHHHCC
NF
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]