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The map label for this gene is dapB [H]

Identifier: 78779352

GI number: 78779352

Start: 899652

End: 900500

Strand: Reverse

Name: dapB [H]

Synonym: PMT9312_0968

Alternate gene names: 78779352

Gene position: 900500-899652 (Counterclockwise)

Preceding gene: 78779354

Following gene: 78779351

Centisome position: 52.69

GC content: 34.75

Gene sequence:

>849_bases
ATGACTGAAAATTCTAAAAAACCCATACCAGTACTAGTCTCCGGAGCTTTAGGCAGAATGGGAAGCGAAGTTGTTAATTC
TGTATTAAATTCAACTGATTGTGAACTTGTTGCAGCAATTGACATAAACGAAAAGAACAATGGATCGAATATTGCTGAAT
TATTGAAAGTAAAAAGTTGTGATGTTTTTCTTTCAAATGATTTTGAGGGGACTTTGTGTTCTGTTAGTCAAAATTACAGA
AATGAAAATATCAAACCAGTCTTGGTTGATTTCACACATCCTGAATCTGTTTATGAAAATACAAGATCAGCTATCGCATA
TGGTATTTCACCAGTAGTCGGAACAACAGGTCTTACTCCTTCTCAAATAAAAGACTTGTCTGTTTTTGCTCAGAAAGCAT
CTGTGGGTTGTGCAATAATACCTAATTTTTCAGTAGGTATGGTTCTTCTTCAGCAAGCAGCATCAGTTGCCGCAAGGTTT
TATGACAATATTGAATTAATAGAGATGCACCATAATCAAAAAGCAGATTCTCCAAGCGGAACATGTATAAAAACTGCAGA
AATGATTGAAGAATATCCAAAGAAATTTAATCAGAGTTTAGTAAATGAGTCTGAGTCATTGAAGGGTGTGCGAGGAGGGC
TTAGGGATTCAGGAATAAATATACATTCGGTACGATTACCAGGATTATTAGCCCATCAATTAGTAATTATGGGATCCCCT
GGTGAAACTTACACAATTAAGCATGACACTATTGATAGAAAAGCATATATGCCAGGTGTTTTACAGGCGGTAAAAAAAAT
AGGTAATTATGAATCTCTAGTTTACGGACTTGAAAAATTGATTTTTTAA

Upstream 100 bases:

>100_bases
ATTTTATTTAAGTATTTCTACCAGCCTACGAATGAAATGACGTTATTGTGTGCAATATAAATAGCGTGTAACAACCTTTT
AAAAAAAAAATTTTTCAAAA

Downstream 100 bases:

>100_bases
AATGCTAATTCCAATTAATTCAAATCAAATCTCGAAACTTATTCCTGCAGTTGGTACTGGGAGTCAATTTAAATATACAT
TGGGTAATCCAAGAAAAATT

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR [H]

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MTENSKKPIPVLVSGALGRMGSEVVNSVLNSTDCELVAAIDINEKNNGSNIAELLKVKSCDVFLSNDFEGTLCSVSQNYR
NENIKPVLVDFTHPESVYENTRSAIAYGISPVVGTTGLTPSQIKDLSVFAQKASVGCAIIPNFSVGMVLLQQAASVAARF
YDNIELIEMHHNQKADSPSGTCIKTAEMIEEYPKKFNQSLVNESESLKGVRGGLRDSGINIHSVRLPGLLAHQLVIMGSP
GETYTIKHDTIDRKAYMPGVLQAVKKIGNYESLVYGLEKLIF

Sequences:

>Translated_282_residues
MTENSKKPIPVLVSGALGRMGSEVVNSVLNSTDCELVAAIDINEKNNGSNIAELLKVKSCDVFLSNDFEGTLCSVSQNYR
NENIKPVLVDFTHPESVYENTRSAIAYGISPVVGTTGLTPSQIKDLSVFAQKASVGCAIIPNFSVGMVLLQQAASVAARF
YDNIELIEMHHNQKADSPSGTCIKTAEMIEEYPKKFNQSLVNESESLKGVRGGLRDSGINIHSVRLPGLLAHQLVIMGSP
GETYTIKHDTIDRKAYMPGVLQAVKKIGNYESLVYGLEKLIF
>Mature_281_residues
TENSKKPIPVLVSGALGRMGSEVVNSVLNSTDCELVAAIDINEKNNGSNIAELLKVKSCDVFLSNDFEGTLCSVSQNYRN
ENIKPVLVDFTHPESVYENTRSAIAYGISPVVGTTGLTPSQIKDLSVFAQKASVGCAIIPNFSVGMVLLQQAASVAARFY
DNIELIEMHHNQKADSPSGTCIKTAEMIEEYPKKFNQSLVNESESLKGVRGGLRDSGINIHSVRLPGLLAHQLVIMGSPG
ETYTIKHDTIDRKAYMPGVLQAVKKIGNYESLVYGLEKLIF

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786214, Length=280, Percent_Identity=26.4285714285714, Blast_Score=81, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040 [H]

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N [H]

EC number: =1.3.1.26 [H]

Molecular weight: Translated: 30609; Mature: 30478

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTENSKKPIPVLVSGALGRMGSEVVNSVLNSTDCELVAAIDINEKNNGSNIAELLKVKSC
CCCCCCCCCCEEECCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHCC
DVFLSNDFEGTLCSVSQNYRNENIKPVLVDFTHPESVYENTRSAIAYGISPVVGTTGLTP
EEEECCCCCCEEEHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCHHCCCCCCCH
SQIKDLSVFAQKASVGCAIIPNFSVGMVLLQQAASVAARFYDNIELIEMHHNQKADSPSG
HHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCC
TCIKTAEMIEEYPKKFNQSLVNESESLKGVRGGLRDSGINIHSVRLPGLLAHQLVIMGSP
CEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEEEEEECCCCEEEEEEEECCC
GETYTIKHDTIDRKAYMPGVLQAVKKIGNYESLVYGLEKLIF
CCEEEEECCCCCHHHCCHHHHHHHHHHCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TENSKKPIPVLVSGALGRMGSEVVNSVLNSTDCELVAAIDINEKNNGSNIAELLKVKSC
CCCCCCCCCEEECCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHCC
DVFLSNDFEGTLCSVSQNYRNENIKPVLVDFTHPESVYENTRSAIAYGISPVVGTTGLTP
EEEECCCCCCEEEHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCHHCCCCCCCH
SQIKDLSVFAQKASVGCAIIPNFSVGMVLLQQAASVAARFYDNIELIEMHHNQKADSPSG
HHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCC
TCIKTAEMIEEYPKKFNQSLVNESESLKGVRGGLRDSGINIHSVRLPGLLAHQLVIMGSP
CEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEEEEEECCCCEEEEEEEECCC
GETYTIKHDTIDRKAYMPGVLQAVKKIGNYESLVYGLEKLIF
CCEEEEECCCCCHHHCCHHHHHHHHHHCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917642 [H]