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The map label for this gene is rnr [C]

Identifier: 78779317

GI number: 78779317

Start: 868491

End: 869675

Strand: Direct

Name: rnr [C]

Synonym: PMT9312_0933

Alternate gene names: 78779317

Gene position: 868491-869675 (Clockwise)

Preceding gene: 78779316

Following gene: 78779318

Centisome position: 50.81

GC content: 22.62

Gene sequence:

>1185_bases
TTGAAAGATTTAACTAATTTAAAAACATATATTATTGACTCTGAAAATCCACATGAAGTCGATGATGCTATTTCCTTAGA
AATAAAAAATGGAAATACAAAAAAACTATGGATACACATTAGTAATCCATGCAAGTTTTTTTTGCATGACTCTAATGTTG
ATCTCGATGCAAGATTGAAAAATAGCAGTTTATATTTGACAGATCAATATGTTCCAATGCTACCTAAGAATATTCTTGAA
AAGGCAAATCTAGCTCAAAATAAAATTTCAGAAACTATTAGTGGAGCAATAGAATTCAACGACGATGGTTCAATTCATAA
TTATGAAATAACTGAAGCAAAAATAAAACCAAAATATCAATTAACATATGAAGATGCAAATGAAATATTAGAATTAGAAC
CTAAAGAAGAAATAGAATTAATTGAGATAAAAAATTTATTAGAAAAAAGTATTTCATTCAGAAAAAAACAAGGAGCAATT
ATATTTGAAAGTCCTAATAGTAAAATTAAATTATATAAGGATAAAATTATACTAAAAAAACTAGATAAAACAATATCACA
ATCTATAGTTTCAGAATCAATGATATTAATGGGTTATGTAACAAGTTTATTTATAGATAAATATAATTTAGCAGCTGCTT
TTAGGATCCAAAAGTTAAATTGCAAACCACATGAAATACTTAATAGATACAATGATAGTGAAATTAAATATATAATATTA
AAACAATATATGGGAAGAAGTTATATAACAACTAAGCCCGGTATCCATGAATCACTAGGCCTTAAAATGTATGTACAATG
TACTTCACCATTAAGAAGATATCTTGATTTAATTATACAAAGACAAGTATATAATAAAATCAATGATTACGAACTTCTAA
GTATAAAATCAGTCTCTGAAATTATTGATTATTCAAAGAATAGACAATCAGAGAATAATAATATATTTAAAAATGATAAA
TTTAAGTATTTAAAATTATTTTTTATGAATGAAAAAAAACCTTTTTATAAAATAATATTTGTTAAGTGGATCAATCATAA
AAGAAATATTGCTTTGGTTTATTTTCCAGATTATTCACTAGAAATACTTATTACTCTTTTTGTATCAATAGAAATATATA
GTAATAAAATATATAAAGTCAAATATATTATAAATGATAGTAATCTTTTAGAATTTATTTATTAA

Upstream 100 bases:

>100_bases
TGTAAAAAGAGCCCGAATTGTAGCTCTCTTACCCTTTGTAAATCCTGAAGGATAATTTCATATTGAATATAGTTAGCTCT
ATAATTAATTTTTCAAATAT

Downstream 100 bases:

>100_bases
TAATATAATAAATATAATAGGTTGTTATTAGTTTAAAAAATATCTGTTAGTATTAATAAAAAAGCTTTATGACTTTTGTC
ATTACTACACCTTTATACTA

Product: putative ribonuclease II

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MKDLTNLKTYIIDSENPHEVDDAISLEIKNGNTKKLWIHISNPCKFFLHDSNVDLDARLKNSSLYLTDQYVPMLPKNILE
KANLAQNKISETISGAIEFNDDGSIHNYEITEAKIKPKYQLTYEDANEILELEPKEEIELIEIKNLLEKSISFRKKQGAI
IFESPNSKIKLYKDKIILKKLDKTISQSIVSESMILMGYVTSLFIDKYNLAAAFRIQKLNCKPHEILNRYNDSEIKYIIL
KQYMGRSYITTKPGIHESLGLKMYVQCTSPLRRYLDLIIQRQVYNKINDYELLSIKSVSEIIDYSKNRQSENNNIFKNDK
FKYLKLFFMNEKKPFYKIIFVKWINHKRNIALVYFPDYSLEILITLFVSIEIYSNKIYKVKYIINDSNLLEFIY

Sequences:

>Translated_394_residues
MKDLTNLKTYIIDSENPHEVDDAISLEIKNGNTKKLWIHISNPCKFFLHDSNVDLDARLKNSSLYLTDQYVPMLPKNILE
KANLAQNKISETISGAIEFNDDGSIHNYEITEAKIKPKYQLTYEDANEILELEPKEEIELIEIKNLLEKSISFRKKQGAI
IFESPNSKIKLYKDKIILKKLDKTISQSIVSESMILMGYVTSLFIDKYNLAAAFRIQKLNCKPHEILNRYNDSEIKYIIL
KQYMGRSYITTKPGIHESLGLKMYVQCTSPLRRYLDLIIQRQVYNKINDYELLSIKSVSEIIDYSKNRQSENNNIFKNDK
FKYLKLFFMNEKKPFYKIIFVKWINHKRNIALVYFPDYSLEILITLFVSIEIYSNKIYKVKYIINDSNLLEFIY
>Mature_394_residues
MKDLTNLKTYIIDSENPHEVDDAISLEIKNGNTKKLWIHISNPCKFFLHDSNVDLDARLKNSSLYLTDQYVPMLPKNILE
KANLAQNKISETISGAIEFNDDGSIHNYEITEAKIKPKYQLTYEDANEILELEPKEEIELIEIKNLLEKSISFRKKQGAI
IFESPNSKIKLYKDKIILKKLDKTISQSIVSESMILMGYVTSLFIDKYNLAAAFRIQKLNCKPHEILNRYNDSEIKYIIL
KQYMGRSYITTKPGIHESLGLKMYVQCTSPLRRYLDLIIQRQVYNKINDYELLSIKSVSEIIDYSKNRQSENNNIFKNDK
FKYLKLFFMNEKKPFYKIIFVKWINHKRNIALVYFPDYSLEILITLFVSIEIYSNKIYKVKYIINDSNLLEFIY

Specific function: 3'-5'Exoribonuclease That Participates In An Essential Cell Function. Acts Nonspecifically On Poly(A), Poly(U) And Ribosomal RNAs. Required For The Expression Of VIrulence Genes In Enteroinvasive Strains Of E.Coli. [C]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribonuclease II (RNB) family [H]

Homologues:

Organism=Escherichia coli, GI87082383, Length=322, Percent_Identity=24.8447204968944, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1787542, Length=320, Percent_Identity=23.4375, Blast_Score=83, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6323943, Length=333, Percent_Identity=29.1291291291291, Blast_Score=102, Evalue=8e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001900
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00773 RNB [H]

EC number: 3.1.13.1

Molecular weight: Translated: 46412; Mature: 46412

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: PS01175 RIBONUCLEASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDLTNLKTYIIDSENPHEVDDAISLEIKNGNTKKLWIHISNPCKFFLHDSNVDLDARLK
CCCCCCCEEEEECCCCCCCCCCEEEEEEECCCCEEEEEEECCCEEEEEECCCCCEEEEEE
NSSLYLTDQYVPMLPKNILEKANLAQNKISETISGAIEFNDDGSIHNYEITEAKIKPKYQ
CCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCCEEEEEEEEEEECCEEE
LTYEDANEILELEPKEEIELIEIKNLLEKSISFRKKQGAIIFESPNSKIKLYKDKIILKK
EEECCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCEEEEHHHHHHHH
LDKTISQSIVSESMILMGYVTSLFIDKYNLAAAFRIQKLNCKPHEILNRYNDSEIKYIIL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCHHHHHHCCCCCCEEEEEE
KQYMGRSYITTKPGIHESLGLKMYVQCTSPLRRYLDLIIQRQVYNKINDYELLSIKSVSE
EHHCCCEEEECCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHH
IIDYSKNRQSENNNIFKNDKFKYLKLFFMNEKKPFYKIIFVKWINHKRNIALVYFPDYSL
HHHCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCEEEEEEEEEECCCCCEEEEEECCCCH
EILITLFVSIEIYSNKIYKVKYIINDSNLLEFIY
HEEEEEHEEEEEECCEEEEEEEEECCCCEEEECC
>Mature Secondary Structure
MKDLTNLKTYIIDSENPHEVDDAISLEIKNGNTKKLWIHISNPCKFFLHDSNVDLDARLK
CCCCCCCEEEEECCCCCCCCCCEEEEEEECCCCEEEEEEECCCEEEEEECCCCCEEEEEE
NSSLYLTDQYVPMLPKNILEKANLAQNKISETISGAIEFNDDGSIHNYEITEAKIKPKYQ
CCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCCEEEEEEEEEEECCEEE
LTYEDANEILELEPKEEIELIEIKNLLEKSISFRKKQGAIIFESPNSKIKLYKDKIILKK
EEECCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCEEEEHHHHHHHH
LDKTISQSIVSESMILMGYVTSLFIDKYNLAAAFRIQKLNCKPHEILNRYNDSEIKYIIL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCHHHHHHCCCCCCEEEEEE
KQYMGRSYITTKPGIHESLGLKMYVQCTSPLRRYLDLIIQRQVYNKINDYELLSIKSVSE
EHHCCCEEEECCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHH
IIDYSKNRQSENNNIFKNDKFKYLKLFFMNEKKPFYKIIFVKWINHKRNIALVYFPDYSL
HHHCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCEEEEEEEEEECCCCCEEEEEECCCCH
EILITLFVSIEIYSNKIYKVKYIINDSNLLEFIY
HEEEEEHEEEEEECCEEEEEEEEECCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]