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The map label for this gene is macB [H]

Identifier: 78779271

GI number: 78779271

Start: 819129

End: 820325

Strand: Reverse

Name: macB [H]

Synonym: PMT9312_0887

Alternate gene names: 78779271

Gene position: 820325-819129 (Counterclockwise)

Preceding gene: 78779272

Following gene: 78779270

Centisome position: 47.99

GC content: 32.33

Gene sequence:

>1197_bases
ATGGCGACCAAAACATTAGTCTCAAACAAATTAAGAAGTTCGTTGACTATGCTAGGAATAATTATAGGAAATGCTTCTGT
AATTACACTTGTTGGGCTTGGGAGAGGTGCTCAAACATTAGCAAAAAATCAATTAAGTAATTTAGGAGCAAATGTATTAT
TTATTGTTCCTGGAAATAATGACACAAGAAGAAGAGGTATTTCATTTCCTAAAAACCTAGTATTAGAAGATGCAGTAGCA
ATAAGTAATCAAGTCCCAACAGTTAAAAAAGTTGCTCCTCAAATCTCTGCTAACGAAATAGTGCAATCAAATTCTAAAAG
TCTAAATATATCAATTGCAGGAGTTACTCCTGAATTTCTTGAAGTTAGAAGCTTTGAAGTAGATAAGGGAAGATTTTTAT
CAAAAAGTGATGTTAATAGTGCAAGAAGTTATGTAGTAATAGGTCCTGATCTTAAAGACGAATTTTTCAAAGATAAATCT
TCATCACTTGGGGAAAAGATTAGAATTAAGGATCATACATATGAAATAATTGGAATTTTAAAACCCAAAGGGGCTGTATT
CGGAAGTAATCAAGACAAAAATGCTTATATTCCATTGACTACTATGGTTAATAGGATTACAGGGAAGGACCCTACATATG
GTGTAAGTTTAAGCTTCATAAGTGTTGAAGCAAAAAATAAAAATGCAACCAGCGCAGCAAAATTTCAAATTACTAACTTA
TTAAGGCAAAGACATAAAATAATAAGAGATGATGATTTTGCAGTTAGATCACAAGAAGATGCATTAAACATAGTAACTAA
TATTACGAGTGGACTAACGTTTCTCTTAGCAGGTATTGGTGCAGTATCTTTAGTAGTTGGAGGTATAGGAATAATGAATA
TTATGCTTGTTTCTGTTAGCGAAAGAACTGAAGAAATAGGTCTTAGAAAGGCAATTGGTGCCAAACAGTCGGATATTTTA
ATTCAATTTTTAATTGAGGCATTGATTTTATCTACAATTGGAGGATTAATAGGAACAACAACTGGATTATCAGGTGTTTT
CATATTATCTCTGATTACACCACTGCCTGCATCTGTAGGTATTACAACTACTTTATCCACAATGATTATTTCAGGATCAA
TAGGTTTGATTTTTGGTGTTTTACCCGCAAAAAGAGCTTCTAAATTAGATCCGATTGTTGCCTTAAGAAGCTTATAA

Upstream 100 bases:

>100_bases
AACGAAGGTGTAATTTATATGGGACAAATTGAAGATGATGAAGAAGCTATAGATAAATATAAATATGTCTAGGAATATCT
CAATAAAGGAAGCCCTAGGC

Downstream 100 bases:

>100_bases
ATAGAATTTATAATCATGTTCAATTTTTATAAATTAATTGAGATATTGGTATGTCTTCAATCAATAATAATATCAACCCT
AATTCCTATTTATATTCCAC

Product: putative ABC transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MATKTLVSNKLRSSLTMLGIIIGNASVITLVGLGRGAQTLAKNQLSNLGANVLFIVPGNNDTRRRGISFPKNLVLEDAVA
ISNQVPTVKKVAPQISANEIVQSNSKSLNISIAGVTPEFLEVRSFEVDKGRFLSKSDVNSARSYVVIGPDLKDEFFKDKS
SSLGEKIRIKDHTYEIIGILKPKGAVFGSNQDKNAYIPLTTMVNRITGKDPTYGVSLSFISVEAKNKNATSAAKFQITNL
LRQRHKIIRDDDFAVRSQEDALNIVTNITSGLTFLLAGIGAVSLVVGGIGIMNIMLVSVSERTEEIGLRKAIGAKQSDIL
IQFLIEALILSTIGGLIGTTTGLSGVFILSLITPLPASVGITTTLSTMIISGSIGLIFGVLPAKRASKLDPIVALRSL

Sequences:

>Translated_398_residues
MATKTLVSNKLRSSLTMLGIIIGNASVITLVGLGRGAQTLAKNQLSNLGANVLFIVPGNNDTRRRGISFPKNLVLEDAVA
ISNQVPTVKKVAPQISANEIVQSNSKSLNISIAGVTPEFLEVRSFEVDKGRFLSKSDVNSARSYVVIGPDLKDEFFKDKS
SSLGEKIRIKDHTYEIIGILKPKGAVFGSNQDKNAYIPLTTMVNRITGKDPTYGVSLSFISVEAKNKNATSAAKFQITNL
LRQRHKIIRDDDFAVRSQEDALNIVTNITSGLTFLLAGIGAVSLVVGGIGIMNIMLVSVSERTEEIGLRKAIGAKQSDIL
IQFLIEALILSTIGGLIGTTTGLSGVFILSLITPLPASVGITTTLSTMIISGSIGLIFGVLPAKRASKLDPIVALRSL
>Mature_397_residues
ATKTLVSNKLRSSLTMLGIIIGNASVITLVGLGRGAQTLAKNQLSNLGANVLFIVPGNNDTRRRGISFPKNLVLEDAVAI
SNQVPTVKKVAPQISANEIVQSNSKSLNISIAGVTPEFLEVRSFEVDKGRFLSKSDVNSARSYVVIGPDLKDEFFKDKSS
SLGEKIRIKDHTYEIIGILKPKGAVFGSNQDKNAYIPLTTMVNRITGKDPTYGVSLSFISVEAKNKNATSAAKFQITNLL
RQRHKIIRDDDFAVRSQEDALNIVTNITSGLTFLLAGIGAVSLVVGGIGIMNIMLVSVSERTEEIGLRKAIGAKQSDILI
QFLIEALILSTIGGLIGTTTGLSGVFILSLITPLPASVGITTTLSTMIISGSIGLIFGVLPAKRASKLDPIVALRSL

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=397, Percent_Identity=34.7607052896725, Blast_Score=214, Evalue=1e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 42403; Mature: 42272

Theoretical pI: Translated: 10.58; Mature: 10.58

Prosite motif: PS00053 RIBOSOMAL_S8

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATKTLVSNKLRSSLTMLGIIIGNASVITLVGLGRGAQTLAKNQLSNLGANVLFIVPGNN
CCCHHHHHHHHHHHHHEEEHEECCCEEEEEEECCCCHHHHHHHHHHHCCCCEEEEEECCC
DTRRRGISFPKNLVLEDAVAISNQVPTVKKVAPQISANEIVQSNSKSLNISIAGVTPEFL
CHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHCCCCEEEEEEECCCHHHH
EVRSFEVDKGRFLSKSDVNSARSYVVIGPDLKDEFFKDKSSSLGEKIRIKDHTYEIIGIL
HHHCEECCCCCCCCCCCCCCCCCEEEECCCCHHHHHCCCCCCCCCEEEEECCCEEEEEEE
KPKGAVFGSNQDKNAYIPLTTMVNRITGKDPTYGVSLSFISVEAKNKNATSAAKFQITNL
CCCCCEECCCCCCCEEEEHHHHHHHHCCCCCCCEEEEEEEEEEECCCCCCHHHHHHHHHH
LRQRHKIIRDDDFAVRSQEDALNIVTNITSGLTFLLAGIGAVSLVVGGIGIMNIMLVSVS
HHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERTEEIGLRKAIGAKQSDILIQFLIEALILSTIGGLIGTTTGLSGVFILSLITPLPASVG
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCC
ITTTLSTMIISGSIGLIFGVLPAKRASKLDPIVALRSL
HHHHHHHHHHCCCHHHHHCCCCCHHHCCCCHHHHHHCC
>Mature Secondary Structure 
ATKTLVSNKLRSSLTMLGIIIGNASVITLVGLGRGAQTLAKNQLSNLGANVLFIVPGNN
CCHHHHHHHHHHHHHEEEHEECCCEEEEEEECCCCHHHHHHHHHHHCCCCEEEEEECCC
DTRRRGISFPKNLVLEDAVAISNQVPTVKKVAPQISANEIVQSNSKSLNISIAGVTPEFL
CHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHCCCCEEEEEEECCCHHHH
EVRSFEVDKGRFLSKSDVNSARSYVVIGPDLKDEFFKDKSSSLGEKIRIKDHTYEIIGIL
HHHCEECCCCCCCCCCCCCCCCCEEEECCCCHHHHHCCCCCCCCCEEEEECCCEEEEEEE
KPKGAVFGSNQDKNAYIPLTTMVNRITGKDPTYGVSLSFISVEAKNKNATSAAKFQITNL
CCCCCEECCCCCCCEEEEHHHHHHHHCCCCCCCEEEEEEEEEEECCCCCCHHHHHHHHHH
LRQRHKIIRDDDFAVRSQEDALNIVTNITSGLTFLLAGIGAVSLVVGGIGIMNIMLVSVS
HHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERTEEIGLRKAIGAKQSDILIQFLIEALILSTIGGLIGTTTGLSGVFILSLITPLPASVG
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCC
ITTTLSTMIISGSIGLIFGVLPAKRASKLDPIVALRSL
HHHHHHHHHHCCCHHHHHCCCCCHHHCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA