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The map label for this gene is ppx [H]

Identifier: 78778842

GI number: 78778842

Start: 431799

End: 433394

Strand: Direct

Name: ppx [H]

Synonym: PMT9312_0457

Alternate gene names: 78778842

Gene position: 431799-433394 (Clockwise)

Preceding gene: 78778839

Following gene: 78778848

Centisome position: 25.26

GC content: 31.45

Gene sequence:

>1596_bases
ATGATACAGAAACAAGATTTAAGATATTTTCAAGAAAAGCAAATTTTAGTAGCTTCTATCGATATTGGAACTAACTCTAC
ACATCTCTTGGTAGCAGAAATTAATCTAGAATTAAAATCATTTTCAATAAAATTCACTGATAAATCAACCACTCGTCTTG
GAGAAAGAAATGAAGAGGGTAATCTTACTGAAGAATCAATCCAAAGAGCATTAGTTACTCTTAAGCGATTTAAGGAATAT
TGTAAAAGTAATGGAGTAAAACAAATAGTAACAGCAGCAACAAGTGCAGTTAGGGAAGCTCCAAACGGTCAAGATTTTAT
TAGAAGAGTTCTTGATGAGACTGAGATTCAAATAGAATTGATAAGTGGTTCTGAGGAAGCCAGATTAATTTACCTTGGTG
TTCTTTCTGGTATGGCTTTTGAAGACCAATCTTATGTAATCATAGATATTGGTGGAGGATCTACAGAATTAATACTTGCA
GATAAAAAAGATGCAATAGCTCTTACCAGCTCGAGAGTTGGTGCGGTAAGACTTAAGAATGATTTTTTAAATAAAGAGCC
TATAAATGTAGAAAGATCAAAGTTTCTAACAACTTTTATTCAAGGTTCTTTAGAACCATCCGTTCGAAAAATAAAGAGTA
GATCTAAGGGAGATAAGCCTTTATCTATGATTGCAACAAGTGGCACTGCCACTTCATTAGGAAATTTGATTTCAGATGAT
TTAGGAGAATCTAAACAAAAGTTGCATGGTTATAAATTTAAAAGGGAAAATTTACAGAATGTATTGGAAAAATTAATTAA
AATGCCAGTTTCGGAAATTAAGAAAATACCTTCATTAAGTGAGAGAAGAGCAGAAATAATTATTCCAGGCGCATTGATAT
TAAATACCGCAATGGGTATGTTGAACTTTAATGAATTAGCTATAAGTGAGAGGGCGCTTAGAGAGGGTTTAGTTGTTGAT
TGGATGCTTCGTAAAGGGATAATAAAAAACGAGTTCAATATACAAAGCAATATTAGAAAAACAACTATAGTTCATCAGGC
CAGAAAGTTTGGAGTAGATAATACAAGGGCTGAGAAAGTTATCGATATTGCTTTTCAAATCTATGATCAGACTAAAAATA
TCTTTCATAACAATAATGACTCTAAAGCTAAAGAACTTCTTTGGGCAGCTTCTAATCTTTATAATTGCGGGAAATACGTA
AATGTTGGTTCATATCACAAACACTCTTGGTACTTAATAAAAAATTGTGAGTTGTTGGGATATTCTGAAGCAGAAACAAA
TATTATTGCTTCGATAGCTAGATACCATAGAAAGACTCTACCCAAGAAAAGACATGAGTCTTGGCAAAATTTAATATCCA
AAGAAGATAAAACATTAGTTCTTGAAATGTCATTAATATTAAGACTAGCAGCATCTCTTGATCAAAGACCTGATAATGTA
ATTTCTTCAGTTCAAATAAAATTGCAGGAAAATATTCTTACATTTGAACTTTTACCTTTAAATAGAAACCATGATCTTCT
ACTTGAAAAATGGAACTTAGGATTATGCCGTAATGTAATAAAAGAACTAAAGAATTTGGATTTAAAAGTTATTTAG

Upstream 100 bases:

>100_bases
TTAAATAATCTTACTAGGATTAAGTGATTCCTATTATTTAATAATCAATCTTGAGTATATTTATTAATGGATTCAAGATA
TCTGCATCTTATAAACAGAA

Downstream 100 bases:

>100_bases
TTTTTTTTAATAACTTCTTGTTTTGGAGTTTGATTCTGAAAAGACTCTGAAAATAAATTGAAAATTAAGGATGAGGCGAC
TAGTCCGAGAAAGCCTGAAA

Product: putative exopolyphosphatase

Products: NA

Alternate protein names: ExopolyPase; Metaphosphatase [H]

Number of amino acids: Translated: 531; Mature: 531

Protein sequence:

>531_residues
MIQKQDLRYFQEKQILVASIDIGTNSTHLLVAEINLELKSFSIKFTDKSTTRLGERNEEGNLTEESIQRALVTLKRFKEY
CKSNGVKQIVTAATSAVREAPNGQDFIRRVLDETEIQIELISGSEEARLIYLGVLSGMAFEDQSYVIIDIGGGSTELILA
DKKDAIALTSSRVGAVRLKNDFLNKEPINVERSKFLTTFIQGSLEPSVRKIKSRSKGDKPLSMIATSGTATSLGNLISDD
LGESKQKLHGYKFKRENLQNVLEKLIKMPVSEIKKIPSLSERRAEIIIPGALILNTAMGMLNFNELAISERALREGLVVD
WMLRKGIIKNEFNIQSNIRKTTIVHQARKFGVDNTRAEKVIDIAFQIYDQTKNIFHNNNDSKAKELLWAASNLYNCGKYV
NVGSYHKHSWYLIKNCELLGYSEAETNIIASIARYHRKTLPKKRHESWQNLISKEDKTLVLEMSLILRLAASLDQRPDNV
ISSVQIKLQENILTFELLPLNRNHDLLLEKWNLGLCRNVIKELKNLDLKVI

Sequences:

>Translated_531_residues
MIQKQDLRYFQEKQILVASIDIGTNSTHLLVAEINLELKSFSIKFTDKSTTRLGERNEEGNLTEESIQRALVTLKRFKEY
CKSNGVKQIVTAATSAVREAPNGQDFIRRVLDETEIQIELISGSEEARLIYLGVLSGMAFEDQSYVIIDIGGGSTELILA
DKKDAIALTSSRVGAVRLKNDFLNKEPINVERSKFLTTFIQGSLEPSVRKIKSRSKGDKPLSMIATSGTATSLGNLISDD
LGESKQKLHGYKFKRENLQNVLEKLIKMPVSEIKKIPSLSERRAEIIIPGALILNTAMGMLNFNELAISERALREGLVVD
WMLRKGIIKNEFNIQSNIRKTTIVHQARKFGVDNTRAEKVIDIAFQIYDQTKNIFHNNNDSKAKELLWAASNLYNCGKYV
NVGSYHKHSWYLIKNCELLGYSEAETNIIASIARYHRKTLPKKRHESWQNLISKEDKTLVLEMSLILRLAASLDQRPDNV
ISSVQIKLQENILTFELLPLNRNHDLLLEKWNLGLCRNVIKELKNLDLKVI
>Mature_531_residues
MIQKQDLRYFQEKQILVASIDIGTNSTHLLVAEINLELKSFSIKFTDKSTTRLGERNEEGNLTEESIQRALVTLKRFKEY
CKSNGVKQIVTAATSAVREAPNGQDFIRRVLDETEIQIELISGSEEARLIYLGVLSGMAFEDQSYVIIDIGGGSTELILA
DKKDAIALTSSRVGAVRLKNDFLNKEPINVERSKFLTTFIQGSLEPSVRKIKSRSKGDKPLSMIATSGTATSLGNLISDD
LGESKQKLHGYKFKRENLQNVLEKLIKMPVSEIKKIPSLSERRAEIIIPGALILNTAMGMLNFNELAISERALREGLVVD
WMLRKGIIKNEFNIQSNIRKTTIVHQARKFGVDNTRAEKVIDIAFQIYDQTKNIFHNNNDSKAKELLWAASNLYNCGKYV
NVGSYHKHSWYLIKNCELLGYSEAETNIIASIARYHRKTLPKKRHESWQNLISKEDKTLVLEMSLILRLAASLDQRPDNV
ISSVQIKLQENILTFELLPLNRNHDLLLEKWNLGLCRNVIKELKNLDLKVI

Specific function: Degradation of inorganic polyphosphates. Orthophosphate is released progressively from the ends of polyphosphate [H]

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gppA/ppx family [H]

Homologues:

Organism=Escherichia coli, GI1788848, Length=430, Percent_Identity=26.7441860465116, Blast_Score=159, Evalue=4e-40,
Organism=Escherichia coli, GI48994966, Length=420, Percent_Identity=27.8571428571429, Blast_Score=140, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022371
- InterPro:   IPR003695 [H]

Pfam domain/function: PF02541 Ppx-GppA [H]

EC number: =3.6.1.11 [H]

Molecular weight: Translated: 60213; Mature: 60213

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQKQDLRYFQEKQILVASIDIGTNSTHLLVAEINLELKSFSIKFTDKSTTRLGERNEEG
CCCHHHHHHHHHCCEEEEEEECCCCCCEEEEEEEEEEEEEEEEEECCCHHHHCCCCCCCC
NLTEESIQRALVTLKRFKEYCKSNGVKQIVTAATSAVREAPNGQDFIRRVLDETEIQIEL
CCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEEEEE
ISGSEEARLIYLGVLSGMAFEDQSYVIIDIGGGSTELILADKKDAIALTSSRVGAVRLKN
ECCCCCCEEEEEEECCCCEECCCCEEEEEECCCCEEEEEECCCCCEEEECCCCCEEEEEH
DFLNKEPINVERSKFLTTFIQGSLEPSVRKIKSRSKGDKPLSMIATSGTATSLGNLISDD
HCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHH
LGESKQKLHGYKFKRENLQNVLEKLIKMPVSEIKKIPSLSERRAEIIIPGALILNTAMGM
CCHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCEEEECHHHHHHHHHHH
LNFNELAISERALREGLVVDWMLRKGIIKNEFNIQSNIRKTTIVHQARKFGVDNTRAEKV
CCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCHHHCCHHHHHHHHHHHCCCCCHHHHHH
IDIAFQIYDQTKNIFHNNNDSKAKELLWAASNLYNCGKYVNVGSYHKHSWYLIKNCELLG
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCEEEC
YSEAETNIIASIARYHRKTLPKKRHESWQNLISKEDKTLVLEMSLILRLAASLDQRPDNV
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHCCCCCHH
ISSVQIKLQENILTFELLPLNRNHDLLLEKWNLGLCRNVIKELKNLDLKVI
HHHHHEEEECCEEEEEEEECCCCCCEEEEECCCHHHHHHHHHHHCCCEEEC
>Mature Secondary Structure
MIQKQDLRYFQEKQILVASIDIGTNSTHLLVAEINLELKSFSIKFTDKSTTRLGERNEEG
CCCHHHHHHHHHCCEEEEEEECCCCCCEEEEEEEEEEEEEEEEEECCCHHHHCCCCCCCC
NLTEESIQRALVTLKRFKEYCKSNGVKQIVTAATSAVREAPNGQDFIRRVLDETEIQIEL
CCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEEEEE
ISGSEEARLIYLGVLSGMAFEDQSYVIIDIGGGSTELILADKKDAIALTSSRVGAVRLKN
ECCCCCCEEEEEEECCCCEECCCCEEEEEECCCCEEEEEECCCCCEEEECCCCCEEEEEH
DFLNKEPINVERSKFLTTFIQGSLEPSVRKIKSRSKGDKPLSMIATSGTATSLGNLISDD
HCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHH
LGESKQKLHGYKFKRENLQNVLEKLIKMPVSEIKKIPSLSERRAEIIIPGALILNTAMGM
CCHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCEEEECHHHHHHHHHHH
LNFNELAISERALREGLVVDWMLRKGIIKNEFNIQSNIRKTTIVHQARKFGVDNTRAEKV
CCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCHHHCCHHHHHHHHHHHCCCCCHHHHHH
IDIAFQIYDQTKNIFHNNNDSKAKELLWAASNLYNCGKYVNVGSYHKHSWYLIKNCELLG
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCEEEC
YSEAETNIIASIARYHRKTLPKKRHESWQNLISKEDKTLVLEMSLILRLAASLDQRPDNV
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHCCCCCHH
ISSVQIKLQENILTFELLPLNRNHDLLLEKWNLGLCRNVIKELKNLDLKVI
HHHHHEEEECCEEEEEEEECCCCCCEEEEECCCHHHHHHHHHHHCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]