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The map label for this gene is prmA

Identifier: 78484787

GI number: 78484787

Start: 494862

End: 495746

Strand: Reverse

Name: prmA

Synonym: Tcr_0442

Alternate gene names: 78484787

Gene position: 495746-494862 (Counterclockwise)

Preceding gene: 78484788

Following gene: 78484786

Centisome position: 20.42

GC content: 46.21

Gene sequence:

>885_bases
ATGGCCTGGATTCAAATCAACACCACTGTTTCAGAAGCGCTTGCGGAACCATTATCGGATGCTTTTATGGAAGTGAACGC
TGCGTCTGTAACGTTTGCAGACGCAAAAGATCAACCTATTTTCGAACCAGAAATTGGCACAACGCCCATTTGGAGTCAAA
CCAAGGTCATTGGTTTATTTGATGCTGAAGCCGACATTCCCGCCGTAATTAATCAATTAGCGACCTTAATACCGGACGTG
CCAGCTGAGCGCTATAACATTGAAGCACTCGAAGATAAAGATTGGATTCGTGCCTGGATGGATCAGTTCCAACCTATGCA
GTTTGGCTCGCGTTTATGGATTGTGCCCAGCTGGTGTGACACTCCTGACCCCAAAGCGGTTAACCTCATGCTGGATCCTG
GCATGGCCTTTGGAACGGGCACTCACCCGACAACGGCTTTATGCCTTACTTGGCTTGACCAAAACCCTCCTACCGATTTA
ACGGTTATTGATTATGGCTGTGGCTCAGGTGTATTGGCGCTTGCCGCTGAAAAGTTAGGCGCAAAGCATGTAAAAGGAAC
GGACATTGATCCACAAGCGATTATTGCCAGTCAGCAAAATGCCGACAGAAATAACGCCAACATTGAATTCAAACTGGTGA
AAGAATTTCAATCCGAACCCGTTGACCTATTAATAGCCAACATTCTTGCAGGCCCGCTCAAAGCGCTTGCACCAGAATTC
ATTCGTTTGATGAAACCCAATGCTACGCTGATTTTATCGGGCCTATTAACCAACCAGGCAGCGGACTTGATTGCCTTTTA
TCAGCAACAAGGGTTTGAGTTTTTAGCTCAGAATGACTTGGATGAATGGTCTCAGCTGAGCTTTACTAAACAAGTGACCT
CTTAA

Upstream 100 bases:

>100_bases
CGTTTAGACTCGAGTTTTCACACAAACCCACTGACATCAACCACGTTGAGCCTATAATGCAATTTATCGGCCACGTGGTT
TTTACGTTTAAAGGACCCAT

Downstream 100 bases:

>100_bases
GTACTTCAACATGATGACGTTATTTGACTCTAGTACCCCCACGATTGCCCTGGCACCCATGGCAGGCATTACCGATCGGG
TTTATCGTGACATTTGTCGA

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MAWIQINTTVSEALAEPLSDAFMEVNAASVTFADAKDQPIFEPEIGTTPIWSQTKVIGLFDAEADIPAVINQLATLIPDV
PAERYNIEALEDKDWIRAWMDQFQPMQFGSRLWIVPSWCDTPDPKAVNLMLDPGMAFGTGTHPTTALCLTWLDQNPPTDL
TVIDYGCGSGVLALAAEKLGAKHVKGTDIDPQAIIASQQNADRNNANIEFKLVKEFQSEPVDLLIANILAGPLKALAPEF
IRLMKPNATLILSGLLTNQAADLIAFYQQQGFEFLAQNDLDEWSQLSFTKQVTS

Sequences:

>Translated_294_residues
MAWIQINTTVSEALAEPLSDAFMEVNAASVTFADAKDQPIFEPEIGTTPIWSQTKVIGLFDAEADIPAVINQLATLIPDV
PAERYNIEALEDKDWIRAWMDQFQPMQFGSRLWIVPSWCDTPDPKAVNLMLDPGMAFGTGTHPTTALCLTWLDQNPPTDL
TVIDYGCGSGVLALAAEKLGAKHVKGTDIDPQAIIASQQNADRNNANIEFKLVKEFQSEPVDLLIANILAGPLKALAPEF
IRLMKPNATLILSGLLTNQAADLIAFYQQQGFEFLAQNDLDEWSQLSFTKQVTS
>Mature_293_residues
AWIQINTTVSEALAEPLSDAFMEVNAASVTFADAKDQPIFEPEIGTTPIWSQTKVIGLFDAEADIPAVINQLATLIPDVP
AERYNIEALEDKDWIRAWMDQFQPMQFGSRLWIVPSWCDTPDPKAVNLMLDPGMAFGTGTHPTTALCLTWLDQNPPTDLT
VIDYGCGSGVLALAAEKLGAKHVKGTDIDPQAIIASQQNADRNNANIEFKLVKEFQSEPVDLLIANILAGPLKALAPEFI
RLMKPNATLILSGLLTNQAADLIAFYQQQGFEFLAQNDLDEWSQLSFTKQVTS

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=241, Percent_Identity=56.8464730290456, Blast_Score=249, Evalue=1e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_THICR (Q31II5)

Other databases:

- EMBL:   CP000109
- RefSeq:   YP_390712.1
- ProteinModelPortal:   Q31II5
- SMR:   Q31II5
- STRING:   Q31II5
- GeneID:   3761469
- GenomeReviews:   CP000109_GR
- KEGG:   tcx:Tcr_0442
- NMPDR:   fig|317025.3.peg.620
- eggNOG:   COG2264
- HOGENOM:   HBG584653
- OMA:   EREEWCR
- PhylomeDB:   Q31II5
- BioCyc:   TCRU317025:TCR_0442-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498
- TIGRFAMs:   TIGR00406

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 32277; Mature: 32146

Theoretical pI: Translated: 4.00; Mature: 4.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWIQINTTVSEALAEPLSDAFMEVNAASVTFADAKDQPIFEPEIGTTPIWSQTKVIGLF
CEEEEECCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEE
DAEADIPAVINQLATLIPDVPAERYNIEALEDKDWIRAWMDQFQPMQFGSRLWIVPSWCD
CCCCCHHHHHHHHHHHCCCCCCCCCCEEEECCHHHHHHHHHHCCCHHCCCEEEEEECCCC
TPDPKAVNLMLDPGMAFGTGTHPTTALCLTWLDQNPPTDLTVIDYGCGSGVLALAAEKLG
CCCCCEEEEEECCCCCCCCCCCCHHHHHEEECCCCCCCCEEEEECCCCCCHHHHHHHHHC
AKHVKGTDIDPQAIIASQQNADRNNANIEFKLVKEFQSEPVDLLIANILAGPLKALAPEF
CCCCCCCCCCHHHEEECCCCCCCCCCCEEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHH
IRLMKPNATLILSGLLTNQAADLIAFYQQQGFEFLAQNDLDEWSQLSFTKQVTS
HHHHCCCHHEEEEHHHHHHHHHHHHHHHHHCHHHHHHCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
AWIQINTTVSEALAEPLSDAFMEVNAASVTFADAKDQPIFEPEIGTTPIWSQTKVIGLF
EEEEECCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEE
DAEADIPAVINQLATLIPDVPAERYNIEALEDKDWIRAWMDQFQPMQFGSRLWIVPSWCD
CCCCCHHHHHHHHHHHCCCCCCCCCCEEEECCHHHHHHHHHHCCCHHCCCEEEEEECCCC
TPDPKAVNLMLDPGMAFGTGTHPTTALCLTWLDQNPPTDLTVIDYGCGSGVLALAAEKLG
CCCCCEEEEEECCCCCCCCCCCCHHHHHEEECCCCCCCCEEEEECCCCCCHHHHHHHHHC
AKHVKGTDIDPQAIIASQQNADRNNANIEFKLVKEFQSEPVDLLIANILAGPLKALAPEF
CCCCCCCCCCHHHEEECCCCCCCCCCCEEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHH
IRLMKPNATLILSGLLTNQAADLIAFYQQQGFEFLAQNDLDEWSQLSFTKQVTS
HHHHCCCHHEEEEHHHHHHHHHHHHHHHHHCHHHHHHCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA